The National MS Society has launched 40 new research awards to explore myelin repair, clues to MS progression, and wellness strategies to move closer to a world free of MS. The $19 million investment is part of a projected total of nearly $30 million in 2022 to support over 250 new research studies.
A study led by McGill University and the Massachusetts Institute of Technology (MIT) found that Ukrainians who engage in more analytic thinking are less likely to believe pro-Kremlin disinformation. Analytical thinking helps curtail belief in disinformation, according to the researchers.
A new study reveals that climate change and population growth are putting UK wastewater treatment works at extreme stress, with dynamic stressors linked to increased risk of pollution events. The research proposes using real-time data to mitigate disruption and improve resilience.
Researchers at Kyoto University have developed a new protocol for synthesizing dialkyl ethers using three catalysts that hydroxylate alkenes quickly and cheaply. This method enables the precise control of electrons and protons to convert unactivated alkenes into reactive carbocation equivalents under mild reaction conditions.
Scientists found that systems exhibiting anomalous diffusion with resetting can only reach equilibrium when fluctuations remain constant over long time intervals. This discovery has potential applications in optimizing industrial and biological processes, such as autonomous cleaning robots.
Researchers mapped specific gene variants to their effects on cardiac cells, revealing unique responses to different mutations. This study provides insights into the development of precision-targeted interventions for dilated cardiomyopathy and other genetic heart diseases.
Staff turnover affects both residents and their families, compromising the quality of care. Continuity of nursing home staff and leadership is essential for delivering personalized care, as frontline workers deliver 90% of care. Researchers emphasize the need to attract and retain well-trained staff who enjoy working with older adults.
Ballistics experts create first precise model of a football's flightpath, shedding light on what separates good passes from bad ones. The study found that the Magnus effect has little impact on a spinning football and that swerving is linked to the ball's orientation at the end of the pass.
Researchers found that higher suPAR levels were associated with increased risk of blood clot formation in COVID-19 patients. Combining suPAR and D-dimer may improve predicting who is at high or low risk of blood clots, enabling targeted therapies to prevent critical outcomes.
Researchers at Cedars-Sinai Cancer identified genetic signatures linked to patient response to immunotherapy in bladder and other cancers. High DDR1 expression is associated with 'cold' tumors, while high DDR2 is linked to 'hot' tumors.
Researchers found that orally administering gold nanoclusters to mice with colitis eliminated reactive oxygen species, increased antioxidant enzymes, and inhibited pro-inflammatory cytokines without side effects. The nanoclusters also showed benefits over natural enzymes used in traditional IBD treatments.
Researchers develop a new low-calorie sweetener that is as sweet as table sugar and feeds beneficial gut microbes. The mixture shows promise in improving gut health and has prebiotic effects on the human gut microbiome.
A new sample preparation method called 'water droplet-in-oil' (WinO) has been developed to improve efficiency in single-cell proteomics. The technique reduces sample loss and increases throughput by up to 10-fold compared to conventional methods.
Stabilized coacervate droplets can be steered using an electric field, allowing for controlled manipulation and delivery of biomolecules like enzymes. The technology has potential applications in drug delivery and other encapsulation technologies, as well as explaining the stability of biological condensates.
Researchers at the University of Tokyo have made a groundbreaking discovery about the development of the visual system in mice. By studying the neural networks in cortical and thalamic regions, they found that parallel pathways from the retinas form earlier than connections within cortical areas, challenging current understanding of co...
Researchers at Washington University in St. Louis developed a new imaging tool that uses optical coherence tomography (OCT) and machine learning to detect and classify cancerous tissue samples with high accuracy. The technique, which was tested on patients in a trial, showed a 93% diagnostic accuracy rate.
Researchers at Ohio State University have developed a new method to synthesize medicines using carbenes, reducing the need for explosive intermediates. This breakthrough could enable faster production of cyclopropanes, a key ingredient in COVID-19 treatments and other medications.
Researchers found that microbes detach from sinking plastic and attach to surrounding water, stopping their descent at a few meters below the surface. Microbial communities on floating plastic particles differ from those in deeper waters.
Researchers analyzed genomic data from 44 women with germline PTEN mutations who developed breast cancer and compared it to sporadic breast cancers. They found that PTEN and PIK3CA were the most frequently somatically mutated genes in PHTS-associated breast cancers, indicating that somatic mutations in PTEN drive these cancers.
Researchers generated rat sperm cells inside sterile mice using blastocyst complementation, achieving a proof-of-principle for producing gametes from one animal species in another. This breakthrough may speed up the production of transgenic rats for biomedical research and potentially support animal species conservation efforts.
Researchers optimized the ZZ SWAP network protocol, introducing a new technique to improve quantum error mitigation. This enables more efficient execution of quantum algorithms like QAOA, which can solve combinatorial optimization problems.
Patients struggle to understand key terms like 'metastatic' and 'carcinoma' found in breast pathology reports. A survey of 527 participants found that only 73% correctly defined 'benign', highlighting the need for educational tools to support patient comprehension.
A study of 168 COVID-19 patients with mild symptoms found that 88% completely recovered from smell or taste dysfunction within two years. For those who took longer to recover, it was over six months
Researchers at KAIST developed a novel fusion protein drug, αAβ-Gas6, which efficiently eliminates amyloid beta (Aβ) without causing inflammatory side effects. The study showed that αAβ-Gas6 promoted the robust uptake of Aβ without inflammation and neurotoxicity.
A new study from UC Davis links air pollution exposure to increased inflammation and decreased cardiac regulation in children. Elevated markers of interleukin-6 and lower cardiac autonomic regulation were found in blood samples of healthy children aged 9-11 who lived near areas with high levels of PM2.5 during wildfires.
The University of Cincinnati is conducting a study on a potential new treatment for pancreatic cancer using SapC-DOPG, a nanotechnology drug delivery system. The treatment has shown promise in reducing tumor growth by 50-80% in animal models and aims to develop an effective immunotherapy treatment.
Researchers identified lipopolysaccharide-responsive and beige-like anchor protein (LRBA) as a crucial regulator of aquaporin-2 water channels in the kidneys. The study found that LRBA interacts with PKA to facilitate AQP2 activation, maintaining water homeostasis and preventing polyuria.
A new study published in Nature Microbiology reveals high prevalence of antibiotic resistance genes in mothers and neonates from 7 LMICs. The researchers found that ARGs were present in neonates within hours of birth, indicating initial colonization with antibiotic-resistant bacteria.
A team of researchers at Mount Sinai discovered a molecular mechanism involving carbohydrate response-element binding protein (ChREBP) that plays a key role in glucose toxicity and beta-cell death. Increasing expression of an alternate form of ChREBP or activating nuclear factor-erythroid factor 2 can preserve beta-cell mass.
Rice University researchers create a technique to make surfaces superhydrophobic by combining sanding with powder materials, resulting in water-repelling properties. The treatment also exhibits excellent anti-icing properties, slowing down freezing and reducing ice adhesion strength.
Researchers have designed a phage combination therapy that precisely targets and suppresses gut bacteria associated with inflammatory bowel diseases (IBD). The team identified effective phages against IBD-contributing Kp strains, which attenuated inflammation and tissue damage in mice models.
A new study analyzing 72 lakes in four large Neotropical wetlands of Brazil reveals that human impacts on biodiversity compromise wetland multifunctionality. Strong associations between aquatic organism diversity and wetland functioning were found, highlighting the crucial role of species richness in driving ecosystem health.
Researchers at Imperial College London developed a new rapid test called CrisprZyme, which detects biomarkers in the body to diagnose non-infectious diseases like heart attacks and cancers. The test works at room temperature with colorimetric analysis, eliminating the need for amplification and temperature control.
The study suggests that COVID-19's direct mortality effects on children may be comparable to the magnitude of indirect outcomes from gun violence. The authors noted a possible increase in gun-related deaths among children due to factors like psychological and economic strain during the pandemic.
Researchers have developed a low-cost, spongy electrode made from a sugar cube template, offering improved signal detection and reduced noise. The device's micropores provide increased contact area with the skin, enabling it to monitor uterine contractions and other health issues with high quality.
Researchers from TU Delft constructed the smallest flow-driven motors in the world using DNA, converting energy into mechanical work. The achievement opens new perspectives for engineering active robotics at the nanoscale.
Researchers from Tokyo University of Science create a metal–organic framework-based magnesium ion conductor showing superionic conductivity at room temperature, overcoming the limitations of magnesium ion-based energy devices. The novel Mg2+ electrolyte exhibits a high conductivity of 10−3 S cm−1, making it suitable for battery applica...
Researchers found that 41% of schizophrenia patients met the criteria for frontotemporal dementia, a condition characterized by personality changes and behavioral alterations. The study suggests that targeting specific brain regions and neural structures may lead to improved treatment outcomes for this subgroup.
Researchers have constructed a comprehensive map of CLL genetic changes, providing a better understanding of the complex malignancy. The study identifies key genes and subtypes with distinct prognoses, paving the way for more accurate diagnoses and personalized treatments.
A study published in Stem Cell Reports found that manipulating two signaling pathways, MAPK and PI3K-AKT, enhances the maturation of human-induced pluripotent stem cell-derived cardiomyocytes. This breakthrough discovery has significant implications for the development of cell therapy for heart disease.
A new study found that 86.6% of people with opioid use disorder are not receiving life-saving medications like methadone, buprenorphine, and extended-release naltrexone. The researchers recommend expanding treatment access by removing barriers, eliminating stigma, and ensuring evidence-based medications are used.
A Houston Methodist study found that a minimally invasive procedure using temperature-controlled radiofrequency intervention is safe and effective in improving symptoms of chronic rhinitis. After 12 months, patients reported a 57.8% improvement in symptoms, with minor side effects observed in a few individuals.
Researchers discovered distinct genetic mutations in heart failure patients, identifying potential targets for personalized treatment and improving patient care. The study's findings hold enormous potential for rethinking how to treat heart failure by understanding its root causes and the mutations that lead to changes in heart function.
The FDA's longstanding confidentiality practices have prevented data sharing with other regulatory agencies worldwide, particularly in low- and middle-income countries. New transparency policies could promote US scientific and regulatory leadership and advance global health by enabling greater data sharing.
Annual PSA screening associated with reduced risk of prostate cancer-specific mortality among non-Hispanic Black men. The study suggests that annual screening may be particularly important for Black men, reducing their risk compared to less frequent screening.
The University of Illinois School is awarding a grant to explore the use of conversational AI in libraries, aiming to strengthen engagement between libraries and diverse audiences. The project will investigate ways to democratize conversational AI for librarians, enhancing workforce development and community service.
An analysis of European data found a significant link between adenovirus and severe liver inflammation (hepatitis) in children under 5. Most affected were those with adenovirus testing positive, with a notable decline in cases after week 17. The study calls for further investigation into the cause of this syndrome.
Researchers found that adult sea urchins can pass on heatwave resistance to their offspring, but this effect may not last throughout juvenile development. The study suggests that different life stages have varying abilities to cope with thermal stress, and that parental conditioning can help juveniles survive in extreme temperatures.
A large population study found a 14% increased risk of developing Crohn's disease among children born via cesarean section. The study suggests an association between cesarean section and altered gut microbiome, warranting further research.
A study of wild baboons in southern Kenya found that most carry traces of hybridization in their DNA, with about a third of their genetic makeup coming from another species. However, new genetic evidence reveals that some borrowed genes came at a cost, affecting the hybrids' survival and reproduction.
Researchers found that DNMT3A and TET2 genes directly activate expression of a gene involved in mitochondrial inflammatory pathways. This activation leads to increased inflammation, which may exacerbate plaque buildup in atherosclerosis. Blocking these pathways could form the basis for new treatments.
Intrinsically flexible displays rely on key materials and devices such as stretchable electrodes, organic semiconductors, and dielectric materials. Researchers focus on improving mechanical stretchability, electrical conductivity, and biocompatibility while maintaining chemical stability.
Rice University mechanical engineers repurpose deceased spiders as small-scale, naturally derived grippers. The spiders can lift more than 130% of their own body weight and perform tasks like sorting or moving objects around. Future research will focus on testing the concept with smaller spiders.
A case-crossover study in 32 Chinese counties linked short-term PM2.5 exposures to increased non-accidental mortality, particularly from combustion sources. Stronger effects were observed for cardiovascular mortality and varied by sex-age subpopulations.
Research highlights the 'worst of both worlds' for people living in suburban areas, with poor access to natural and built infrastructure. This can result in a lower quality of life compared to urban and rural areas.
Researchers have synthesized novel nitrogen compounds with ring- and spiral-shaped crystal structures under extremely high pressure. The new polynitrides contain planar, symmetrically constructed ring structures and a rare polynitrogenic double helix.
Researchers have created a cheap and energy-efficient way to capture carbon dioxide from smokestacks using porous melamine material. The process is simple to make and requires primarily off-the-shelf melamine powder, making it a promising solution for scaling down carbon emissions from vehicle exhaust or other movable sources.
Researchers at Max Planck Institute for Psycholinguistics found that our brain is a prediction machine continuously making predictions on multiple levels. They analyzed brain activity while people listened to Hemingway or Sherlock Holmes stories and text, finding the brain response was stronger when words were unexpected in context.
Researchers developed a new technology that can detect early-stage hepatocellular carcinoma using nanoparticles, which are released by tumor cells and can be detected in circulation. The technology, called HCC EV SPA, has the potential to enable rapid and affordable detection of the disease, leading to improved survival rates.
A 60-year study found that building mental resilience through education, socializing, and exercise can reduce dementia risk even among those with low childhood cognition or genetic predisposition. Participants with higher cognitive reserve index and reading ability showed slower cognitive decline.
Researchers have constructed the most complete single-cell map of fruit fly embryo development, enabling a continuous view of molecular changes driving embryonic development. This study provides a significant advance in understanding the complex process of embryogenesis and its relationship to gene regulation.
A research group from Osaka Metropolitan University investigates Adiabatic State Preparation (ASP) for efficient electron correlation effects in molecules. They find four key points relevant to ASP's computational conditions, making the method more practical.
A new study based in Africa reveals hidden selection against interspecies breeding in wild baboon species. The findings highlight the crucial role of other living primates as models for understanding human evolution, particularly for phenomena that are impossible to study in our lineage alone.
A four-year project funded by the US Department of Education will investigate academic outcomes for adolescent immigrant English learners in Texas schools. The study aims to develop reading interventions to accelerate literacy among these students, who face unique challenges due to their linguistic and cultural backgrounds.
Researchers have discovered a novel strategy for preventing and treating parasites and allergies by harnessing the power of adenosine, a molecule released by injured cells. This breakthrough could lead to the development of vaccines and treatments that target this 'danger signal', which is released when cells are damaged.
Holocentric chromosomes have been found to promote rapid genome evolution by allowing the formation of new species through chromosome fusions. This non-classical mode of chromosome organization also stabilizes chromosomal fragments and facilitates DNA gene swapping, making it an exciting area for plant breeding.
Scientists discover guanylate-binding proteins that can directly kill specific types of bacteria, offering new treatment options for drug-resistant infections. These proteins can also be used in combination with existing antibiotics to enhance treatment effectiveness.
A study co-authored by Rotman School professor Partha Mohanram has received the 2022 Notable Contributions to Accounting Literature Award. The research used textual analysis techniques to predict firm-level earnings and stock returns based on Twitter activity, demonstrating significant predictive power.
Researchers developed a flexible, stretchable computing chip that processes information like a human brain to analyze health data. The device aims to change the way health data is processed, enabling continuous tracking of health without sending data wirelessly.
A study led by Drs. Wei Song and Xue-Yan Liu found that microbial nitrogen oxide emissions account for 24% of global NOx emissions, equivalent to fossil fuel emissions. The research uses new nitrogen isotope methods to constrain ocean and land NOx emissions from microbial N cycle.
Robert Reinhart's work utilizes noninvasive neuromodulation technology to develop personalized treatments for cognitive brain disorders. His research shows significant improvements in age-related memory function and compulsive behaviors with high-definition transcranial alternating current stimulation.
Grasses supply crucial ecosystem services, including food for humans and animal habitats, but are threatened by land-use conversion and climate change. Research highlights the need to better understand their functions to inform policy and management.
Researchers developed a new tool to measure moral distress in pandemic nursing care, capturing COVID-19-specific sources of nurses' moral distress. The COVID-MDS has promise to address urgent questions and advance efforts to prevent or mitigate moral distress.
Researchers successfully taught microrobots to swim via deep reinforcement learning, allowing them to adapt to changing conditions and perform complex maneuvers. The AI-powered swimmers can navigate toward any target location on their own, showcasing their robust performance in fluid flows and uncontrolled environments.
Researchers used single-nucleus RNA-sequencing to study heart tissue from patients with cardiomyopathies and found distinct cell types involved in pathogenesis. Genotype-associated pathways were also identified, providing evidence that genotype influences pathological remodeling of the heart.
Scientists at UC San Diego and Salk Institute discover link between mitochondrial function, inflammation, and DNMT3A and TET2 genes in atherosclerosis. Abnormal inflammatory signaling is triggered by low levels of these genes, leading to excessive plaque buildup.
A recent study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that vegan participants who engaged in regular resistance training had stronger bones than those who did not. The study also showed that vegans and omnivores who performed resistance training had similar bone structure.
Argonne researchers develop a new way to calculate the environmental impact of ammonia production, evaluating two promising methods: carbon capture and water electrolysis. The study aims to reduce greenhouse gas emissions and fossil fuel use in fertilizer production.
A new study is providing training to mothers of infants at the Linda Ray Intervention Center, equipping them with a critical caregiving skill. The program focuses on infant-directed singing, which has been shown to help babies regulate their emotions and develop self-regulation skills.
A study by Durham University researchers found that bonobos produce specific 'baby-like' signals to express emotional distress and increase the chances of receiving comfort from others. These signals, such as pouting and whimpering, can also reduce the likelihood of re-attack after a conflict.
Researchers at Stanford University have developed Unified Many-Worlds Browsing, a new approach to refine the search process for physics-based animations. By allowing animators to create queries to narrow down options, this framework can potentially reduce thousands of possible outcomes to a handful that are interesting to the user.
Researchers developed a ligand exchange strategy to create atomically thin 2D cuprate layers with active periodic copper single sites, which catalyze efficient Chan-Lam coupling. These 2D-CuSSs show advantages over traditional homogeneous counterparts due to their large open surface and abundant undercoordinated Cu single sites.
A large Dutch study found that 12.7% of adults infected with SARS-CoV-2 experience long-term symptoms, including breathing problems and fatigue, three to five months after infection. The study suggests that these symptoms can be used to distinguish between post-COVID-19 condition and non-COVID-19-related symptoms.
Researchers at KAIST have developed a method to produce lutein in E. coli bacteria using glycerol as a cheap carbon source. The production process involves systems metabolic engineering and substrate channeling to overcome bottleneck enzymes that inhibit lutein biosynthesis.
Researchers from Aarhus University are developing a new approach to turbulence modelling using physics-constrained machine learning to accurately simulate complex turbulent systems. The goal is to reduce computational costs while maintaining accuracy, enabling more efficient designs and predictions in various fields.
ARID1A-deficient bladder cancers are sensitive to combination therapies with the EZH2 inhibitor GSK-126 and inhibitors of PI3K, acting synergistically. The research found that tumors deficient in ARID1A protein have elevated levels of PIK3R3 and phosphoAKT.
A Swedish study of over 4,000 adults found that those with high prostasin blood levels were 76% more likely to develop diabetes and 43% more likely to die from cancer. Prostasin may be an indicator of disease occurrence or causally relevant, raising the possibility of targeting this protein for future treatments.
The new database offers improved estimations of Potential Evapotranspiration and Aridity Index for the entire world at a high spatial resolution. This allows for a finer description of water needs in different regions, enabling better resource management and land-use planning.
A research team led by Prof. Dr. Birte Höcker applied a computer-based natural language processing model to protein research, creating new proteins capable of stable folding and defined functions. The ProtGPT2 model generates proteins with differentiated structures, eliminating the need for functionalization processes.
A new study on parabiosis found that young mice exposed to old blood experienced a significant decrease in lifespan. The research suggests that aging factors in older blood can induce aging in younger animals, challenging the idea that 'young' blood holds anti-aging properties.
Scientists have identified a previously unknown plant mechanism driving gene expression during meiosis, enabling germ cell and pollen differentiation. This discovery holds potential for developing more resilient crops adapted to harsher environmental conditions.
Researchers have developed a novel approach to engineering live bacterial therapeutics by using native microbes that can survive in the gut. This method overcomes previous limitations of introducing engineered bacteria into the gut, demonstrating potential for long-term therapy and reversal of disease pathologies in mouse models.
A new study from Tokyo Institute of Technology introduces a novel crystal engineering strategy to design ultrabright fluorescent solid dyes. This approach allows for monomeric emission and suppressed intermolecular interactions, enabling the creation of highly dense crystalline structures with controlled electronic properties.
A Phase 1 clinical trial found a monoclonal antibody to be highly protective against malaria in US adults. L9LS was administered subcutaneously and fully protected 88% of participants from infection.
A new water-resistant gas sensor can detect nitrogen dioxide in breath, indicating potential pulmonary diseases. The sensor's semi-permeable membrane allows it to block moisture while permitting gas molecule permeation.
A study found eight classes of health conditions common among pediatric obese patients, including respiratory and sleep disorders. The researchers used a pattern mining algorithm on electronic health records of 49,694 patients to identify clinically similar subtypes.
Researchers developed a new method to synthesize polyimidazolium organic cages that can encapsulate metal nanoparticles, leading to improved catalytic performance. The new catalysts show superior activity in various reactions, with tunable NHC sites enhancing interactions between the shell and the metal nanoparticles.
Researchers tracing nitrogen pollution affecting the Mesoamerican Reef Region reveal that agricultural operations are responsible for the vast majority of nitrogen pollution. The study highlights the need for tailored management strategies to mitigate nutrient input and protect coral reef and seagrass health.
Researchers at Queen's University Belfast have secured a £228,900 grant to develop an mRNA vaccine targeting protein p53 in triple negative breast cancer. The project aims to improve treatment options for patients with this aggressive form of the disease.
A new scientific statement from the American Heart Association finds that social isolation and loneliness are associated with a 30% increased risk of heart attack or stroke. Younger adults, including Gen Z, experience increased social isolation and loneliness due to higher social media use and less in-person engagement.
A new study published in Cochrane Reviews found that tocolytics, or preterm delay treatments, are beneficial for women worldwide. The researchers reviewed 122 clinical trials and concluded that the benefits of these drugs outweigh any risks associated with side effects.
Researchers, led by TUM's Senthold Asseng, are exploring ways to close the genetic yield gap of 51% in wheat to meet increasing global demand. Utilizing advanced breeding techniques and interdisciplinary approaches combining genetics, soil, and climate science can lead to richer harvests.
TCT 2022 will feature late-breaking clinical science presenting the safety and effectiveness of minimally invasive techniques, pharmaceuticals, technologies, and devices for treating or preventing cardiovascular disease. The event takes place September 16-19 in Boston at the Boston Convention and Exhibition Center.
Research finds that grassland biodiversity and resilience are the result of a slow process over hundreds of years, not rapid recovery. Ancient grasslands have unique characteristics that develop over time and can be conserved to maintain ecosystem functions.
The NIH has launched an experimental science rigor initiative to improve the quality of research funded by the National Institutes of Health. The initiative provides a comprehensive, modular, and adaptable platform to host educational content on rigorous research, supporting the development of courses in experimental rigor.
The NCI-backed Molecular Targets Platform streamlines and catalyzes drug development by integrating pediatric cancer targets and pathways. This platform empowers researchers, pharmaceutical companies, and advocacy groups to accelerate the pace of drug development for pediatric cancer.
A study by UT Southwestern researchers found an 'infodemic' of misinformation and disinformation on Twitter using #scamdemic and #plandemic hashtags, with 80% of users left to post false information. The work aims to combat echo chambers and promote accurate health messaging on social media.
Microglia that express the APOE4 gene cannot metabolize lipids normally, leading to a buildup of excess lipids that interferes with nearby neurons' ability to communicate. Restoring normal lipid metabolism in microglia may help treat some symptoms of Alzheimer's disease.
A new Oregon State University study found significant differences in hop aroma profiles between Oregon and Washington-grown hops, affecting beer flavor. The research suggests that regional identity, similar to terroir in wine, can be attributed to specific growing environments.
Researchers examine voting decisions when favored candidates commit moral transgressions, identifying key factors affecting support. Strong ideological identity and severity of transgression influence voter loyalty, with significant differences between conservatives and liberals.
Researchers at Dartmouth Cancer Center developed a new approach for detecting and quantifying tumor heterogeneity in breast cancer. High levels of heterogeneity are linked to poor patient outcomes, while specific proteins regulate its extent. The study aims to utilize this approach in therapeutic decision-making.
Researchers have developed a novel dual-atom catalyst design that can reduce the environmental impact of ammonia production. The new design uses a hybrid of iron and molybdenum to activate dinitrogen, resulting in a more efficient and eco-friendly method for ammonia synthesis.
Researchers developed a monoclonal antibody that binds E-cadherin, strengthening cell adhesion and preventing cancer metastasis. The antibody, 19A11, has two binding modes that increase adhesive strength through salt bridge formation.
Researchers developed a method to produce generic CAR T cells from induced pluripotent stem cells (iPS cells), which could be produced at scale for multiple patients. The new cells showed enhanced anti-tumor activity and comparable efficacy to current clinical-grade cells.
Researchers successfully engineered E. coli collected from human and mice gut microbiomes, showing potential to treat diseases such as diabetes. The engineered bacteria retain their activity for the entire lifetime of the host and positively influence diabetes progression in mice.
New research suggests that plant-based beef alternatives could reduce US carbon footprint by 2.5-13.5%, mostly by decreasing cow numbers. However, this shift could disrupt the agricultural workforce, threatening up to 1.5 million industry jobs and exacerbating issues like fair wages and health equity.
Researchers have developed a new chip-based beam steering device that eliminates aliasing errors, enabling high-quality beam steering over large fields of view. The device, published in Optica, has the potential to revolutionize lidar applications in autonomous driving, virtual reality, and biomedical sensing.
A recent study from the University of Geneva suggests that ketamine's therapeutic use may be safe due to its limited impact on dopamine levels and neuronal communication. The research found that ketamine triggers a short increase in dopamine, but also inhibits a specific receptor that prevents addiction progression.
New research reveals that only 1 in 5 Syrian children living in refugee camps exhibit resilience to mental health problems. The study found that factors such as the child's environment, caregiver interactions, and access to resources significantly impact their ability to recover from war trauma.
A recent study published by the German Cancer Research Center found that inflammation in early life leads to a permanent decline in functional blood stem cells, suppressing their ability to regenerate. Mice exposed to inflammatory challenges developed clinically relevant features of aging, including anemia and decreased number of cells...
A new study reveals that droughts in the Amazon rainforest can lead to a ripple effect, causing widespread damage and biodiversity loss. The research team used network analysis to understand the complex workings of the forest's moisture recycling system.
The study investigated the effects of combined endocrine-disrupting chemicals (EDCs) on liver function and metabolic homeostasis in mice models. Significant changes were observed at high EDC exposure levels, including liver weight increase, lipid buildup, and elevated blood glucose levels.
A recent study published in Science reveals that hyaluronic acid plays a key role in controlling muscle repair. The natural compound awakens stem cells to start the repair process after a 40-hour cleanup job by immune cells is complete.
Scientists have identified a critical source of essential molecules that enables the intestine's self-renewal and regeneration after injury. The study reveals that lymphatic endothelial cells play a key role in maintaining stem cell activity and tissues in the intestine.
A computational modeling study explores the relationship between desire for more and happiness, finding a potential bias in our pursuit of pleasure. The research suggests that this bias can lead to unhappiness, highlighting the importance of balance and moderation.
Scientists at KAUST have successfully created a semiconductor material with multiple exciton generation, resulting in a photocurrent quantum efficiency of over 100%. This breakthrough could lead to improved solar cells and light-harvesting applications.