Researchers discovered a novel interaction between the SARS-CoV-2 Spike protein and human Estrogen Receptor Alpha, which may contribute to severe coagulopathy in COVID-19 patients. The study suggests that modulating ER signaling could mitigate rare vaccine side effects.
A new study developed a traveling-wave amplifier based on a photonic integrated circuit operating in the continuous regime, providing 7 dB net gain on-chip and 2 dB net gain fiber-to-fiber. This achievement enables unlimited application areas for LiDAR and other optical sensing applications.
A low-cost prenatal intervention benefits mothers’ mental health up to eight years later. The eight-week class intervention supported healthier stress responses in their children, and cut their short-term risk of depression and diabetes.
Astronomers have discovered a mysterious bright flash emanating from a relativistic jet of matter streaking out from a supermassive black hole. The signal, AT 2022cmc, is the brightest TDE ever detected and originates from a black hole that suddenly began devouring a nearby star, releasing an enormous amount of energy.
The FDA ban on flavored e-cigarettes did not lead to a significant decrease in adult vaping rates. In fact, many users switched to other flavored e-cigs or tobacco products. The study suggests that policy loopholes and the availability of newer products contributed to the failure of the ban.
A new study published in Clinical Infectious Diseases found that severe undernutrition before and during TB treatment significantly increases the risk of death, treatment failure, and relapse. Researchers from Boston University School of Medicine followed nearly 3,000 persons with TB disease for two years and recorded data on demograph...
A recent study highlights the importance of addressing negative human histories in shaping conservation practices. The authors propose a three-step approach to overcome social-ecological landscapes of fear, which constrain research and hinder ecological inquiry. By recognizing past injustices and engaging with local communities, scient...
Researchers from Children's Hospital of Philadelphia identified several genetic variants associated with increased cancer risk in children with non-chromosomal birth defects. The study found that these variants were more commonly found in genes related to birth defects and cancer, suggesting a potential basis for early detection.
Researchers found that female rhesus macaques become increasingly selective in their social interactions as they get older, focusing on relatives and established friendships. This trend suggests that females play an active role in shaping their social networks, rather than being shunned by society.
Researchers at VCU Massey Cancer Center discovered the inactivation of NF1 as a potential genetic driver for pancreatic cancer. The study suggests that targeting NF1 could create vulnerabilities for therapeutic advantage in mutant KRAS-bearing tumors.
The Eurasian Ice Sheet sculpted Europe's landscape through extreme erosion over the last 100,000 years, with climate and geology playing key roles. The study reveals vast networks of subglacial rivers, promoting faster ice flow and sediment transport, with significant implications for marine carbon sinks and coastal communities.
A small study funded by NIH found that a simulated driving program can reduce crashes and near-crashes among teens with attention-deficit/hyperactivity disorder (ADHD) by nearly 40%. The program, called FOCAL+, teaches teens to avoid long glances away from the roadway.
A team of Oregon State University scientists used biophysical techniques to study the malfunctioning motor protein dynein, which is associated with neurodegenerative diseases like ALS and Alzheimer's. The study sheds light on how dynein's transport machinery fails in these disorders, leading to the accumulation of misfolded proteins.
A new study reveals that microfibers in the Mediterranean Sea are home to over 2,600 bacterial species, including Vibrio parahaemolyticus, a potentially deadly bacterium. The presence of these bacteria poses a significant threat to human health and aquatic ecosystems.
Astronomers have made the first-ever discovery of a rare cosmic 'lunch' involving a black hole devouring a nearby star and releasing relativistic jets further out into the universe. The event, AT2022cmc, was detected using a novel data-crunching method that quickly identified it in ZTF survey data.
The Fannie and John Hertz Foundation has announced a new $5 million fellowship in honor of Dr. Nathan Myhrvold, a renowned inventor and entrepreneur. The fellowship program supports the doctoral education of students in applied physical and biological sciences, mathematics, or engineering.
A team of scientists has identified three new biomarkers for detecting the consumption of emerging synthetic cannabinoids like OXIZID. These biomarkers will facilitate work by drug enforcement agencies worldwide in monitoring OXIZID abuse, enabling more accurate identification of abusers and potentially preventing overdoses.
A new serological test, PepSeq, allows scientists to quickly test antibody binding against hundreds of thousands of protein targets, helping prepare for and respond to pandemics. The technology identifies specific antibodies that provide protection against infection, holding promise for developing effective vaccines and treatments.
A new study published in Drones found that drones emit more noise than visual impact, causing behavioral changes in large terrestrial mammals. The Asian elephant was particularly sensitive to low-frequency sounds, highlighting the need for drone safety regulations.
Researchers developed an approach to connect Spanish-speaking smokers with tobacco treatment delivered by state Quitlines, leading to improved treatment enrollment and smoking cessation outcomes. Patients who received treatment in Spanish completed more counseling calls and were more likely to report abstinence from smoking than those ...
The study found that the Erfurt Jewish community was more genetically diverse than modern-day Ashkenazi Jews, with at least two distinct groups. The research team discovered that the founder event, which makes all Ashkenazi Jews today descendants of a small population, happened before the 14th century.
The European Union's H2020 SHOWCASE project has launched an open access collection in the Research Ideas and Outcomes journal, providing a comprehensive overview of its work and development. The collection showcases the project's synergy between agriculture, biodiversity, and ecosystem services, highlighting its contributions to transp...
Researchers link fentanyl to sodium pockets in nerve cell receptors, blocking harmful side effects while reducing pain. The study offers promise for safer painkillers and potential improvements for addressing the nation's crisis of addiction and overdose.
A recent survey of adults found that several medical phrases are frequently misinterpreted, leading to incorrect treatment and care. The study highlights the need for clear communication between healthcare providers and patients to avoid misunderstandings.
Researchers have developed a hybrid plasma accelerator that combines two methods for electron acceleration, achieving better stability and higher particle density than single-accelerator systems. This innovation opens up new possibilities for precision X-ray generation and novel applications in fields like medical imaging and ultrafast...
Researchers have uncovered a new mechanism of antibiotic resistance in Group A Streptococcus bacteria, making antibiotics ineffective and potentially leading to poor outcomes. The discovery highlights the complexity of understanding AMR and emphasizes the need for rapid diagnostic tools and therapeutics.
A pilot study found that nearly half of patients treated with aflibercept could safely stop eye injections without vision loss, while only 17% of those on bevacizumab were able to do so. The findings suggest that matching patients with the right therapy may reduce the need for lifelong treatment.
Research on Fanconi anemia reveals its link to aggressive head-and-neck tumors due to gene-copy chaos, increasing the need for new treatments. The study also highlights a connection between smoking and drinking and elevated cancer risk.
Researchers found that buprenorphine use was associated with better outcomes for the baby, including lower risk of preterm birth, small size for gestational age, and low birth weight. The study suggests increasing access to buprenorphine treatment among pregnant individuals with opioid-use disorder.
A study published in Neurology found that people with higher scores for subjective cognitive decline were more likely to develop dementia. The study, which followed participants over five years, found that every additional point on the scale increased dementia risk by 8.5%.
Researchers identify POLQ's vital role in responding to DNA replication stress and its potential as a cancer target. Inhibiting POLQ may limit mutation diversity and cancer evolution, offering new hope for cancer treatment.
Researchers have enabled remote tuning of coupled Dirac plasmon excitations in graphene by designing an additional damping pathway through adjusting the Fermi energy level. The results provide fresh concepts for active control of other quasiparticle lifetimes and applications in nanophotonics.
Researchers at UC challenge current timeline for mammoth extinction, citing limitations in dating environmental DNA. The team suggests that the slow decomposition of animals in arctic regions could explain how mammoth DNA is showing up thousands of years later than expected.
The UMass Lowell-led team aims to understand how proteins affect biting function in animals, with potential applications in treating diseases like muscular dystrophy. The research will involve studying molecular properties of myosin, a fibrous motor protein, and its impact on muscle force and velocity.
A study published in Nature Communications suggests that small asteroids are probably young because of their loose internal structure and low cohesion. This finding has important implications for understanding the geological development of asteroids.
The new monochromator optics increase photon flux in the tender X-ray range by a factor of 100, allowing highly sensitive spectromicroscopic measurements with high resolutions. This enables data collection on nanoscale materials, such as catalytically active nanoparticles and modern microchip structures, for the first time.
Researchers analyzed observational data from a major field campaign in 2020 and found that trade-wind clouds' contribution to climate warming has been overestimated. The study shows that the clouds are more resilient to global warming than previously thought, which can improve the accuracy of future climate projections.
Researchers at Karolinska Institutet found that internet-delivered anonymous cognitive behavioural therapy (CBT) significantly reduced the viewing of child sexual abuse material. The study, published in Internet Interventions, shows promise for a feasible and effective treatment approach.
The study examines the role of halide ions in enhancing CO2 conversion efficiency and highlights three areas for further research: designing model systems, developing advanced in-situ characterization tools, and exploring new halide-based catalyst architectures.
Researchers have discovered that nanodiamonds can emit solvated electrons in water when exposed to visible light, a crucial step towards using them as photocatalysts. This discovery could lead to the development of inexpensive and metal-free processes for converting CO2 into valuable hydrocarbons or converting N2 into ammonia.
Research highlights the need for high-quality studies on tropical cyclones in low- and middle-income countries to understand long-term consequences. The public health impact extends beyond injuries and cardiovascular diseases, affecting neuropsychiatric conditions and infectious diseases.
A new EU-funded research project aims to improve understanding of mental health by combining biological and social factors, focusing on four critical life stages: early life, puberty, peripartum, and old age. The project seeks to develop personalized preventive and therapeutic measures and reduce stigma associated with mental illness.
Researchers used AI to design and test thousands of functional group patterns on a carbon nanotube pore, finding optimal arrangements that can filter out contaminants. The study demonstrates AI's potential in developing new types of water purification membranes.
Researchers from Japan Advanced Institute of Science and Technology have developed a sustainable, eco-friendly compound to stabilize high-energy density lithium-ion batteries. The microbially synthesized pyrazine diamine compound significantly improves battery performance, reducing degradation and increasing operating potential.
A new study found that around a third of genetic variants associated with autoimmune and allergic disorders were under natural selection, indicating their importance for human adaptation. The research suggests that these genes may have been selected to combat pathogens but now contribute to disease pathology.
Researchers found that stimulating estrogen receptor beta alters dozens of cancer-related genes, slowing the growth and metastasis of triple-negative breast cancers. Higher levels of ER beta expression are associated with longer survival rates in TNBC patients.
A recent human study published in Antioxidants found that consuming grapes protected against ultraviolet (UV) damage to the skin. The study showed increased resistance to sunburn and unique microbiomic and metabolomic profiles in subjects who consumed whole grape powder, suggesting a correlation between the gut and skin.
A study found that Antarctic ice-free areas will create new habitats for some species, but also increase competition and risk of invasion by non-native species. The research highlights the need to address key questions about the impacts of these changes on biodiversity.
Researchers from Okinawa Institute of Science and Technology (OIST) have developed a machine learning-based method to discover non-intuitive pulse sequences that can cool mechanical objects to ultracold temperatures faster than traditional methods. This breakthrough showcases the utility of artificial intelligence in quantum technologies.
A new visual scale called Matches Measure can quickly assess job burnout, reducing participant fatigue and increasing understanding. The scale is comparable to existing burnout measures and relates to known predictors and consequences of job burnout.
Researchers have developed a quantum experiment that allows them to probe connections between theoretical wormholes and quantum physics. The study demonstrates the equivalence of wormholes with quantum teleportation, a process experimentally demonstrated over long distances.
A new study found that when there are more females than males in colonies of orb-weaving spiders, males fight less with each other and females exhibit less aggression. The researchers also observed cooperation among spiders in constructing their webs and wrapping prey in silk.
A minimally invasive treatment for carpal tunnel syndrome provides complete and long-term relief to patients. Ultrasound-guided hydrodissection effectively treats nerve entrapments without surgery or corticosteroids.
The UNC School of Medicine lab, led by Bryan L. Roth, MD, PhD, solved the high-resolution structures of drug-like compounds bound to designer brain cell receptors, paving the way for more effective therapeutics for neuropsychiatric illnesses.
A team led by University of Maryland astronomer Igor Andreoni discovered a bright optical flare caused by a dying star's encounter with a supermassive black hole. The event, AT2022cmc, is extremely rare and was found using a novel data pipeline that analyzed the Zwicky Transient Facility survey.
A study funded by the American Academy of Neurology found that only a small percentage of people with neurologic conditions are being treated with new medications, despite their higher costs. The study also revealed that out-of-pocket costs for new drugs are highly variable and unpredictable compared to existing medications.
Researchers found that antibiotic treatment led to significant changes in Candida albicans populations, varying by individual's microbiota. The degree of fungal overgrowth depended on the activity of beta-lactamase enzyme produced by endogenous bacteria.
A new gene therapy approach has been developed to boost the expression of the beta-3 adrenergic receptor in heart cells, improving mitochondrial function and preventing or reversing heart failure in a mouse model of aortic stenosis. This could potentially provide new therapeutic options for patients with this condition.
Researchers created a stretchable film that can distinguish between different types of sugar using fluorescent signals. The film changes color when stretched, producing a kaleidoscope effect and enhancing the unique shifts in fluorescence intensity of sugars tagged with a dye.
Researchers found a way to use phthalates in plasticizers as mediator for chemical reaction, allowing for electrochemical recycling without heat. The process reduces hydrochloric acid release and improves efficiency.
A new diapsid reptile species has been discovered in Oklahoma with evidence of dental pathology, providing insights into its biology and evolution. The fossil, dated to the early Permian period, was analyzed using neutron tomography and revealed abnormalities in its teeth.
Researchers analyzed GPS tracks of 46 wandering albatrosses to understand their airspeed increases with wind speed up to 20 m/s. The birds limit their airspeed by adjusting turn angles to maintain wing strength, while exploiting updrafts over waves in low winds.
A study found that concerns about colonoscopy, lack of opportunity to discuss next steps with a medical provider, and assumptions about personal risk are common reasons patients don't follow up after a positive at-home test. Researchers also developed two simple risk measurement tools to predict COVID-19 mortality rates, which could he...
Researchers found that a gene mutation in mice resulted in increased plaque deposits and larger clumps, suggesting the gene plays a critical role in immune defenses. The study may lead to new therapies targeting this gene mutation to slow progression of Alzheimer's disease.
Scientists have developed a detailed 'atlas' of human fetal brain development, revealing the origin of aggressive medulloblastomas. The study identifies a collection of progenitor cells that give rise to these tumors and provides potential targets for therapy.
A new study finds that different definitions of whole-grain foods yield varying results on American consumers' intake, highlighting the need for a standardized consensus. While overall consumption has increased, it remains below recommended levels, with discrepancies among racial/ethnic groups and across institutions.
Great gray owls have a broad disc-like face that acts as radar to find food, while their facial features help correct for sonic distortions caused by snow. The owls' ability to hover above prey allows them to pinpoint location and avoid acoustic mirages created by the snow.
A recent study found that carbon dioxide changes the way macronutrients are stored and reallocated in the body of bumblebee queens. The researchers discovered that carbon dioxide induces a change in metabolism, which then triggers secondary effects on reproduction, contrary to previous hypotheses.
A new study by UC Davis suggests that online learning during the COVID-19 pandemic was detrimental to teens' mental health, school satisfaction, and performance. Teens who attended school in-person reported more social inclusion and fewer mental health issues than those learning online.
A team of researchers has discovered how pore space geometry affects the transport of substances through complex porous media. By studying microchips with varying obstruction geometries, they found that branching and junctions play a crucial role in controlling the direction and speed of fluid flow.
A new study from Brigham Young University found that most people on social media self-censor their comments to avoid conflict, while those on the margins fuel online dialogue. The study suggests a shift towards polarized conversations and encourages users to focus on solutions rather than defending identities.
A team of scientists analyzed ancient DNA from medieval German Jews and found that the Ashkenazi Jewish community was more genetically diverse than modern-day Jews. The study suggests that the founder event occurred before the 14th century, with a small population giving rise to the modern Ashkenazi Jewish population.
A new study explores how teenage boys are taught about consent in schools and how they interpret educational messages. The research highlights the need for a more nuanced approach to consent education, addressing ambivalence, ambiguity, and uncertainty.
Researchers are developing new male birth control options that could provide a safer and more effective alternative to hormonal methods. Non-hormonal approaches targeting proteins essential for sperm production are showing promise in clinical trials with minimal side effects.
A new species of ancient bird, Janavis finalidens, has been found with a mobile beak, challenging the long-held assumption that modern birds evolved from a 'ancient jaw' group. The fossil shows a fused palate bone, similar to those of ostriches and their relatives.
The study found that earthquake-accelerated landslides (EALs) can maintain accelerated motion for a long time after the earthquake, causing particularly serious human casualties in seismically active areas. Satellite radar observations detected and investigated EALs in Central Italy, leading to the first ever complete EAL inventory.
A global Phase 2/3 clinical trial found that vaccination with SCB-2019 reduced the risk of transmitting SARS-CoV-2 infection to household members. The study showed a significant reduction in symptomatic cases among vaccinated household contacts and indicated that vaccines can play an important role in controlling future outbreaks.
Researchers found a strong association between hotter weather, more sunshine, and higher volumes of polytrauma CT scans. The study used machine learning algorithms to forecast daily polytrauma CT occurrence, predicting 73% of high-demand days and 83% of low-demand days.
Researchers at Osaka Metropolitan University have successfully created the smallest mobile lifeform, a synthetic bacterium named syn3, capable of swimming. By introducing seven proteins, they were able to reconstitute a minimal motility system based on Spiroplasma swimming, revealing that only two proteins were necessary for movement.
A new PET imaging method is more effective than angiograms in determining the need for coronary stents or bypass surgery, according to UTHealth Houston researchers. The study confirms that PET threshold of severity at which stents and bypass surgery improve survival compared to medical treatment alone.
Research reveals that individuals with autism have normal pain thresholds but increased sensitivity to painful stimuli. This study's findings suggest the need for increased awareness and early treatment to improve quality of life for autistic individuals.
A study published in Nature reveals that cancer stem cells' miscommunication with their environment can trigger a self-perpetuating series of events leading to malignancy. Leptin signaling plays a surprising role in this process, which could be blocked to prevent tumor progression.
Researchers identify INPP5D as a key player in the inflammation process contributing to Alzheimer's disease, which may offer new potential targets for therapies. The study found that mice with inactivated INPP5D gene had more plaques covered by microglia, suggesting unexpected results when modulating inflammation genes.
Researchers at Pusan National University have developed a new, energy-efficient process to control the orientation of filler particles in thermally conductive polymer composites. This allows for improved heat dissipation in electronics and batteries, reducing energy costs and extending device lifespan.
Researchers at IRB Barcelona have developed a new tool to block protein-protein interactions, a potential therapeutic approach for diseases such as prostate cancer. The synthetic molecules mimic the binding surface of proteins, offering high versatility and stability.
A new study found that only 37% of participants with limited English proficiency were offered a choice of language support, highlighting the need for improved interpreting services. The study also identified barriers such as difficulties in requesting an interpreter and waiting times over a week for availability.
Researchers at Chalmers University have developed an optical hydrogen sensor that can detect extremely low levels of hydrogen, allowing for early detection and alarm. The sensor uses AI technology to optimize particle arrangement and geometry, achieving sensitivity in the parts per billion range.
Researchers at Case Western Reserve University are developing a new treatment for Candida auris, a multidrug-resistant yeast that causes serious infection and death. The five-year NIH grant will enhance an antifungal drug developed by SCYNEXIS to prevent the spread of the fungus.
A large US study found that excess oxygen during surgery is associated with a higher risk of kidney, heart, and lung injury. The study of over 350,000 patients suggests that liberal use of oxygen may be harmful to the body's cells and tissues.
A recent research study led by David Almeida found that daily stressors and people's reactivity to them decrease with age. As younger individuals juggle multiple roles, their social roles and motivations change as they age, leading to fewer stressors.
Researchers at UCI discovered that removing cilia from the striatum region impairs time perception and judgment, affecting motor responses and decision-making. This finding may lead to new therapeutic targets for schizophrenia, Parkinson's disease, and other conditions.
Researchers discovered that ant pupae secrete a fluid that is consumed by both adults and larvae, highlighting the interconnectedness of different developmental stages within an ant colony. The fluid, derived from molting, is rich in nutrients and psychoactive substances, essential for larval growth and adult metabolism.
A new study has shed light on the lost medieval chapel of St Erasmus at Westminster Abbey, revealing its role as a royal burial site and its connection to the cult of a disembowelled saint. The chapel, demolished in 1502, is believed to have held relics, including a single tooth, and featured gruesome images of the saint's martyrdom.
Researchers at University of Pennsylvania School of Engineering and Applied Science developed a new electrostatically controlled clutch that enables soft robotic hands to hold 4 pounds, 40 times more than before. The clutch uses a fracture-mechanics-based model to achieve this feat while requiring only 125 volts of electricity.
A survey by UCI MIND found that media coverage of the FDA's decision made people less willing to volunteer for Alzheimer's pharmaceutical trials. The study highlights the powerful influence of media coverage on scientific research and emphasizes the need for diverse populations in clinical trials.
Astronomers have detected the most distant black hole swallowing a star, with the event occurring one-third of its current age. The discovery was made using ESO's Very Large Telescope (VLT) and provides new insights into these extreme events.
Researchers find that heat stress drastically reduces red coral larvae survival, while white gorgonian larvae show higher tolerance but limited dispersal. This could compromise coral populations' ability to cope with climate change.
The study uses 3D electron microscopy and live cell imaging to observe molecular tethers between organelles. These dynamic structures are constantly binding and unbinding, altering contact site configuration in response to cellular changes.
A new study by Anglia Ruskin University found significant disparities in job application outcomes based on age, gender, and race. The research revealed that younger candidates were more likely to receive job interviews and higher salaries compared to older workers from diverse backgrounds.
Researchers investigate how voice technology affects consumers' willingness to disclose personal info, with potential benefits for marketers and policymakers. The study reveals that voice technology can both increase and decrease disclosure, depending on the context.
A recent study published in Psychological Science found that women are less likely to participate in Q&A sessions at academic conferences due to anxiety about receiving professional backlash. Despite this, men were also found to hold back questions, but for different reasons, highlighting the need for structural changes to create a mor...
A Finnish study found that cumulative adverse psychosocial factors in childhood are associated with poorer learning and memory in midlife. Specifically, poor self-regulatory behavior and social adjustment in childhood linked to poorer learning ability and memory decades later.
Researchers at The Forsyth Institute have made two breakthrough discoveries that could lead to new treatments for cartilage injuries and degeneration. They found that β-catenin, a multifaceted protein, plays a role in skeletal cell fate determination and ectopic chondrogenesis.
CHOP researchers identified a gain-of-function variant in SCN1A that leads to an earlier onset of epilepsy, with clinical features distinct from other epilepsies. The study found that patients with this recurrent variant responded favorably to oxcarbazepine, a readily available anti-seizure medication.
Researchers developed a new method to detect lung cancer using machine learning and statistical techniques, identifying 7 specific volatile organic compounds in breath samples. This breakthrough could lead to earlier diagnosis and improved treatment outcomes for patients.
A comprehensive analysis of quality improvement initiatives in operating rooms reveals that sustainability interventions can significantly reduce costs and decrease carbon footprint. The study identified effective strategies such as powering down lights and equipment, reducing waste, and implementing recycling programs.
Researchers analyzed metal ingots from a 14th century B.C. shipwreck to understand the origins of copper and tin used in bronze production. The study found that two-thirds of the tin came from Turkey, contradicting previous assumptions about its source.
Researchers found a strong association between rare tandem repeats in genes crucial for brain function and the development of schizophrenia. The study used whole-genome sequencing and machine learning techniques to analyze the genomes of 2,100 individuals, including those with and without schizophrenia.
Researchers at MIT have discovered that the adult brain contains millions of silent synapses, which may explain how the brain forms new memories without modifying existing connections. These inactive connections can be recruited to help form new memories when important new information is presented.
A Texas A&M team will leverage single-cell sequencing technology to improve cancer diagnosis, treatment, and prevention. The project aims to develop novel statistical methods for analyzing single-cell RNA-sequencing data to reveal medically important information about cancer.
Researchers developed a novel 3D printing technique to fabricate complex metal–plastic composite structures with arbitrarily complex shapes. The process, called MM-DLP3DP, allows for the creation of precise metal patterns and high-quality metal coatings, enabling the development of highly integrated and customizable microelectronics.
A team of researchers from Cornell University has developed a method to study delayed earthquake triggering in laboratory settings. They found that the speed and strength of 'creep fronts' are sensitive to fault stress levels from previous earthquakes, which could potentially serve as local stress meters for predicting seismic events.
Researchers identified formic acid as a sensitive urinary biomarker for early-stage Alzheimer's disease, which could lead to large-scale screening programs. The study found that formic acid levels correlate with cognitive decline and can predict disease stage when combined with blood-based biomarkers.
A study by researchers at Boyce Thompson Institute has identified genes that can help plant breeders develop fruit crops that can adapt to drought conditions. The research found that water stress triggers physiological disorders and fruit loss, but also has positive effects such as increasing lycopene levels in ripe fruit.
Physicists at Google Quantum AI have produced quantum states that exhibit special symmetries, protecting them from environmental noise. The researchers used superconducting qubits to realize symmetry-protected Majorana edge modes, which last longer than other quantum states.
Research finds that crowding on public transit makes time seem to pass more slowly, with rushed commutes feeling significantly longer. The study used virtual reality simulations of subway rides and found that crowded trips took around 10% longer than less crowded ones.
A new study from the University of East Anglia found that overweight women are more likely to experience symptoms of long Covid. The research also shows that people with long Covid are much more likely to need additional and lasting NHS care than those who make a swift recovery.
A new AI method has analyzed substance use trends among Canadian high schoolers, identifying factors such as large weekly allowances and low physical activity that increase the risk of transitioning to multiple substance use. The study found that once students start using substances, it is rare for them to stop, highlighting the need f...
The Wuhan University research team has developed a powerful model called FingerDTA, which uses convolutional neural networks to predict drug-target binding affinity. This can help identify potential novel drug candidates and reduce costs and time in traditional drug discovery methods.
Researchers believe a black hole suddenly began devouring a nearby star, releasing energy and creating the brightest ever recorded TDE. The jet's direction may be pointing towards Earth, causing Doppler boosting, and could reveal insights into how supermassive black holes grow.
Researchers argue that cognitive transformations are crucial in understanding desistance from crime. Individuals' cognitive shifts, such as attitudes and intentions, serve as foundations for social development, including behavioral changes related to criminal behavior.
A large study from Argentina found that COVID-19 vaccines remain effective in preventing death in children and adolescents, regardless of the predominant circulating variant. The study's results show that vaccinated children had a 67% reduced risk of death related to COVID-19 infection during the omicron period.
Researchers at the University of Illinois created an experimental data set to validate models of supersonic flows around a cantilever plate. The data set reveals complex fluid-structure interactions, including three-dimensional flow in the re-circulation region under the plate.
Researchers used large-scale data analysis to study Alzheimer's disease, revealing patterns that can be targeted for tailored intervention. The findings outline a multilevel biological classification system that predicts disease severity and future neurological symptoms.
Researchers developed a lightweight, ultra-shock-absorbing foam that outperforms existing materials in mitigating concussions. The new material exhibits superior mechanical properties and can remain robustly shock-absorbing across various temperatures.
Researchers found shared genetic factors that contribute to severe COVID-19 risk and blood analyte levels. High triglyceride levels were strongly linked to increased risk of severe disease, supporting the use of lipid-lowering drugs against severe COVID-19.
A nationwide data set of 59,000 full-time undergraduate students revealed that fully online courses were associated with increased levels of psychological distress. Students in mixed online-in-person classes showed lower distress levels compared to those attending solely online classes.
The Phase II/III study found that acoziborole has an 18-month treatment success rate of 95% for late-stage patients and 100% for early-stage patients, with no significant safety concerns reported. This breakthrough could lead to the elimination of sleeping sickness through a simplified 'screen-and-treat' approach.
Researchers found increased wasteosomes in the brain, a manifestation of chronic glymphatic insufficiency. The finding suggests that this condition may be associated with ageing, cardiovascular disorders, and poor sleep quality.
A new non-hormonal gel blocks sperm by reinforcing cervical mucus barrier, demonstrating high effectiveness in reducing uterine sperm numbers. The gel has shown a 98% average decrease in sperm numbers compared to untreated control animals, making it a promising alternative to existing contraceptives.
A study by UTHealth Houston reveals a unique fibrotic gene signature in non-resolvable COVID-19 patients, who experience prolonged pulmonary effects following infection. Lung transplantation is often required for survival due to the rapid progression of damage to lung tissue.
Observing the five Buddhist precepts appears to reduce the influence of perceived stress on depression. High levels of neuroticism and stress may be less likely to develop depressive symptoms if followers closely adhere to these moral practices.
Chronic social defeat stress impairs brain reward function, leading to severe social avoidance. A subset of susceptible mice exhibit heightened activity of lateral septum neurotensin neurons, which inhibit centers encoding social rewards.
Scientists have successfully demonstrated light-induced locomotion in a nonliquid environment using antimony telluride plates. The new type of motion, driven by thermal effects, enables efficient actuation in vacuum systems, opening up possibilities for mobile photonic modulation and multimode micro robots.
Researchers analyzed a child's genetic data to identify novel mutations in the GTF3A gene, which impair the innate immune response. The study found that these mutations make cells more susceptible to HSV-1 infection and loss of antiviral immune response.
Researchers investigate Earth's oldest evidence of life in ancient stromatolites, while also studying strike-slip faulting and its connection to climate. Additionally, scientists explore the potential for finding life on Mars by analyzing rare earth elements and geological features.
A post-pandemic outbreak of a drug-resistant fungus in Brazil was linked to the misuse of medications and full ICUs. The study found that 90% of infected patients had strains resistant to fluconazole and echinocandins, leading to high mortality rates.
A team of scientists found that small communities in Central Asia produced and supplied one-third of the tin found on a 3,000-year-old shipwreck. The tin was then traded to markets around the Mediterranean to make bronze metal.
Researchers studied the strong nuclear force using nickel-64 nuclei, discovering that they change shapes under high-energy conditions. The team used advanced detectors to analyze gamma rays and particle direction, revealing two possible shapes for the nucleus: oblate and prolate.