A new study by the University of Michigan estimates that 19 million children under 18 live with a parent who meets the definition for a substance use disorder, with 6 million also having a mental illness. Effective treatment options are available to parents and need to be expanded to support these children.
The study examines energy scenarios that align with the Sustainable Development Goals (SDGs) and the Paris Agreement, finding that sustainable development scenarios significantly reduce extreme poverty. Under these scenarios, the number of people without enough energy to meet basic household needs is projected to decrease by over 90%.
This study identified paravalvular leak (PVL) in 8.1% of surgical aortic valve replacement cases, with the majority being mild in severity. PVL was most frequently observed at the mid-portion of the right coronary cusp and showed significant correlations with calcification sites on the preprocedural aortic valve.
A study of oyster fossils from the Early Cretaceous period reveals significant seasonal temperature fluctuations and periodic glacial melt events, overturning the traditional view of greenhouse climates. The findings suggest that elevated greenhouse gas concentrations may amplify seasonal extremes rather than lead to uniform warming.
A new study suggests that including pork in plant-forward diets makes meals more appealing and just as healthy, offering a higher protein quality score compared to plant-based proteins. The study found that meals with lean pork delivered significantly better results for satisfaction, satiety, and willingness to adopt post-trial.
Researchers discovered that butterflies use body pitch to generate aerodynamic forces and sustain hovering flight. By adjusting their body angle, they counteract gravity and achieve stable flight. This finding could revolutionize the design of stealthy MAVs with low structural demands.
A study analyzing clinical notes found stigmatizing language was more common in Black patients' charts, with 54.9% experiencing bias. Hispanic and Asian/Pacific Islander patients also showed disparities in documentation, highlighting the need for culturally sensitive practices in perinatal care.
A UNIGE team shows that particles can be measured jointly without physical proximity, using quantum entanglement to link separate particles. This breakthrough enables promising applications in quantum communication and computing.
The Boston Children's Therapeutic & Medical Device Accelerator has announced its inaugural awardees, selected for their groundbreaking innovations in pediatric healthcare. The program provides targeted funding, expert mentorship, and strategic collaborations to advance hospital discoveries towards clinical impact.
A new national survey conducted by Ipsos on behalf of The Kids Mental Health Foundation, identifies parents' greatest fears for their children around screen time. Parents' top fears include privacy and safety concerns, exposure to misinformation, and not socializing in person.
Researchers developed a novel CMOS chip-based phased-array receiver that maximizes satellite performance by supporting dual-polarized beams, enabling greater communication flexibility. The innovation doubles the number of controllable beams and improves system capacity, making it crucial for real-world deployments.
The study analyzes 369,161 posts from Reddit's 'AITA?' board, finding that dilemmas concerning relational obligations were the most common type. Violations of trust, such as lying and cheating, were evaluated more negatively than acts of harm, highlighting the importance of trust in moral cognition.
Researchers analyzed online forum conversations to find that incels offer an ideological rationale for not working or studying, often reinforced by peer pressure. The study suggests a need for education and employment support programs addressing alienation and social rejection.
A new study proposes a risk-aware optimal dispatch strategy for resource aggregators, combining probabilistic renewable energy prediction and bi-level building flexibility engagement. The strategy results in cost savings and reduced carbon emissions for both the aggregator and the building cluster.
Zhaoqi Yan, a scientist at Gladstone Institutes, has been awarded the 2025 Warren Alpert Distinguished Scholar fellowship to investigate the molecular mechanisms behind blood-brain barrier dysfunction. His research aims to develop new therapeutic strategies for neurological diseases, including Alzheimer's.
A new AI model can predict protein location in human cells with high accuracy, enabling faster diagnosis of diseases like Alzheimer's and cancer. By combining protein sequence analysis with computer vision, the model can pinpoint proteins' locations at the single-cell level.
A new study published in Nature reveals that maintaining a healthy diet is the most effective way to rebuild a depleted gut microbiome, outperforming fecal transplants. The research shows that a Western-style diet can severely impact the microbiome's ability to defend against pathogens.
Research suggests that physical activity and organized sports participation can help ward off childhood mental ill health, with benefits seen in boys. However, findings indicate sex differences in protective effects, with boys showing stronger associations between physical activity and lower risk of depression, anxiety, and addiction.
Researchers from ETH Zurich have discovered a new class of vulnerabilities in Intel processors that can be exploited to gain unauthorized access to information from other users. The 'BPRC' vulnerability affects all Intel processors and can be triggered by special inputs, allowing attackers to read sensitive information.
Coastal lagoons are becoming increasingly salty due to climate change, affecting microbial life and ecosystem services. Restoration efforts can mitigate the impacts by restoring environmental flows, upgrading wastewater plants, and increasing nutrient retention.
JMIR Mental Health is seeking rigorous research on AI-powered therapy bots and virtual companions for mental health. The journal aims to explore their effectiveness, limitations, and place within broader care models.
A new study by Western University found that passive scrolling is associated with heightened anxiety, depression, aggression, and impulsiveness in adolescents. Exceeding two hours of weekday screen time doubled the odds of clinically elevated anxiety, quadrupling emotional and behavioral difficulties.
Researchers discover certain skin bacteria metabolize cis-urocanic acid using enzyme urocanase, fine-tuning immune response to UV radiation. This finding opens the door to microbiome-aware sun protection, where resident microbes are considered in sun protection strategies.
Preliminary research suggests that long working hours can induce neuroadaptive changes in the brain, particularly in areas associated with emotional regulation and executive function. The study found increased brain volumes in regions such as the middle frontal gyrus, which is involved in attention and problem-solving.
A new study uses explainable machine learning to predict metastasis and mortality in children with medulloblastoma, identifying key immune factors driving risk. The model provides a transparent approach to prognostic accuracy and supports personalized clinical decision-making.
A new analysis of 100 top TikTok videos about food noise found that half reference the use of medications, mainly anti-obesity drugs, to manage constant thoughts about food and eating. The study highlights the potential risks of misinformation on social media platforms like TikTok.
Researchers found that social rank influences vulnerability to drug addiction by altering dopamine pathways. Winning experiences can reshape the brain's dopamine system, reducing drug-seeking behaviors in low-ranking mice.
Researchers at the University of Oklahoma discovered that FGF21 can reverse fatty liver disease in mice by sending signals to both the brain and liver. The study provides valuable insight into the mechanism of action of FGF21, a target for a new class of highly anticipated drugs.
This observational study of the MIMIC-IV database identifies Charlson Comorbidity Index (CCI), red blood cell count (RBC), and red cell distribution width (RDW) as significant predictors of 90-day readmission in heart failure patients. RBC and RDW show linear correlation, while CCI and age display nonlinear correlation.
A study by National Center for Respiratory Medicine identified upper airway cough syndrome (UACS) as a key characteristic of early responders to chronic cough treatment. Higher baseline cough numeric rating scale (NRS) scores were also associated with early response, suggesting shorter treatment durations may be considered.
A new study from the University of Kansas analyzed how professional women soccer players in Europe use social media to promote their personal brand. The research found that when a player's team shared its social media presence with a men's team, it negatively affected women players' following.
A research group at Chuo University has developed an all-printable device fabrication strategy to overcome technical limitations of multi-functional image sensor sheets. The new technique accurately prints carbon nanotube channels and integrates other constituents into single devices, facilitating non-destructive monitoring.
The article reviews current AI applications in chemical product design, process synthesis and design, process control and monitoring, and process safety and hazards. Hybrid AI approaches are being developed to find optimal processing routes and designs, considering sustainability criteria.
A robotic hand developed at EPFL can pick up 24 different objects with human-like movements that emerge spontaneously due to compliant materials and structures. The device uses 'self-organized' grasps that mimic natural human grips with a high success rate, making it suitable for highly unpredictable environments.
Researchers at Washington State University have developed a new 3D printing method for smart fabrics that improve comfort and durability. The technology uses biodegradable materials and a more environmentally friendly process, allowing fabrics to withstand repeated washings and abrasion tests.
Researchers used CT scanning to study decomposing zebrafish without altering the natural decay process, providing unprecedented insights into fossil formation. The non-invasive technique allows scientists to monitor decay in real-time, including the buildup of decomposition gases within internal cavities.
A new data approach using deep learning methods has been developed to improve plant prediction accuracy. The method combines data from four wheat breeding programmes and trial data, resulting in a training set of up to 9,500 genotypes. This allows for more accurate genomic predictions, breaking down data silos across companies.
Researchers at University of Oxford provide key ingredients for finding natural geological hydrogen, essential for a carbon neutral future. The discovery could unlock a commercially competitive, low-carbon hydrogen source, contributing significantly to the global energy transition.
Researchers, Mollie Brewer and Kevin Childs, are exploring how coaches use data and technology to maximize player performance and safety. They found that coaches analyze data from wearable sensors to determine when players need rest or additional training, and that AI-powered analytics can improve team strategy.
Researchers developed an innovative deep-learning-based framework that uses common surveillance cameras to estimate rainfall in real time. The approach achieved high predictive accuracy across various environmental conditions and lighting scenarios, outperforming traditional methods while maintaining low computational costs.
A new study by University of Cincinnati researcher Edson Chipalo found that children who experienced adverse childhood experiences are at a higher risk of homelessness during their childhood. The study highlights the need for prevention and early support to reduce long-term risks associated with childhood trauma.
Researchers found that only a small fraction of proteins have genetic differences between males and females. Instead, lifestyle, education, and access to resources also contribute to the health gaps experienced by men and women.
A study found that state-level abortion policies diverge from public preferences in the US, with Democrat-leaning states having more permissive laws than residents preferred. Republican-leaning states have more restrictive laws in line with resident opinions.
Peiyu Yang will examine how China and Arab world solidarity was framed in official and popular publications from 1949 to 1969. The project aims to understand the role of language and communication in shaping this solidarity.
A study by Incheon National University researchers reveals how audience costs impact US allies' foreign policy decisions, with prevailing pro-US sentiment enhancing credibility of alignment commitments. The study found that citizens who lean towards China tolerate or even reward alignment reversals.
The American College of Medical Genetics and Genomics (ACMG) commends NASEM for its report on sustaining and advancing excellence in newborn screening. The report outlines nine recommendations to improve the program, including national leadership, multistakeholder input, and expanded education and awareness.
Contrasting seismicity in oceanic subduction zones is attributed to varying thermal structures, which control fluid/melt migration and earthquakes. The study reveals that thermal structure, fluid activity, and earthquake mechanisms play a crucial role in shaping the seismic behavior of these zones.
Research reveals rural preschoolers spend more time on screens and engage in less physical activity than their urban counterparts. The study found 24% of rural children have overweight or obesity, compared to 16% in urban areas.
A study published in Nature Neuroscience has uncovered the neural mechanisms by which social rank influences vulnerability to drug addiction. The research found that low-ranking mice exhibit a stronger reward circuit and weaker control circuit, making them more likely to seek drugs.
Researchers found that 'Shall Issue' regulations contribute to a significant increase in handgun purchases, with over 70% driven by repeat gun buyers. In contrast, 'Permitless Carry' policies showed no noticeable effect on gun purchases.
Key findings reveal oxidative stress as a prominent area in COPD studies, with hot topics including air pollution, cigarette smoke extract, and mitochondrial dysfunction. The study highlights the need for targeted antioxidants to effectively treat COPD.
New research from the University of Bath shows that lower taxes on heated tobacco products in Ukraine are benefiting the tobacco industry's bottom lines at the expense of governments and consumers. The study found a significant increase in demand for HTPs, while traditional cigarette sales declined.
Employees who experience negative work experiences cope better when recognized by their colleagues. Research reveals that appreciation from colleagues can help prevent feelings of embitterment, leading to improved mental recovery after work. The study emphasizes the importance of workplace recognition in protecting employees' wellbeing.
A new research study published in Alzheimer's & Dementia found that increased sedentary behavior in aging adults is associated with worse cognition and brain shrinkage. Participants who spent more time sedentary were more likely to experience cognitive decline, even if they exercised regularly.
A cross-sectional study analyzing over 18,000 clinical notes found notable disparities in stigmatizing and positive language documentation across racial and ethnic groups. The study highlights the need for improved documentation practices to reduce stigmatizing language use.
A study at the University of Trento has observed the brain activity of honey bees during sleep and identified similarities with human sleep patterns. The researchers used a combination of optical brain imaging, machine learning analysis, and computational neural modelling to analyze how sleep influences sensory perception in bees.
A breakthrough all-oral treatment for a rare but deadly strain of sleeping sickness is now available, revolutionizing care for patients in endemic countries. Fexinidazole Winthrop has been approved for use in several African countries and is being distributed by WHO, offering a safer alternative to existing treatments.
A new guidebook from Northern Arizona University provides essential support for individuals and communities affected by wildfires in Arizona. The comprehensive resource covers topics such as insurance, erosion control, emotional recovery, financial aid, and more to help residents recover from the aftermath of these devastating events.
A new treatment approach significantly improves survival rates for patients with aggressive, inherited breast cancers. In a trial where cancers were treated with chemotherapy followed by a targeted cancer drug before surgery, 100% of patients survived the critical three-year period post-surgery.
Spearhead Bio's TAHITI technology enables seamless integration of genes into crops, promising faster and cleaner path to crop improvement. The startup aims to generate next-generation improved crops with desired traits, improving speed to market and consumer acceptance.
Researchers developed a tin (Sn)-modified Ce–Nb mixed-oxide catalyst that enhances NOx conversion rates and hydrothermal stability. The study provides a promising solution for diesel vehicle emission control, improving air quality and meeting environmental regulations.
Scientists from Florida Atlantic University have identified a mechanism that enables HIV-1 to hijack human immune cells using circular RNAs, which trap microRNAs to weaken the immune response. The findings reveal a previously hidden layer of HIV biology and offer new possibilities for treatment.
Researchers identify enlarged salience network as first reliable biomarker for depression risk, predicting symptoms before they appear. The network's expansion could enable early identification and intervention, leading to improved quality of life and treatment outcomes.
Researchers at UCL and the Francis Crick Institute have identified the origin of cardiac cells using 3D images of a heart forming in real-time. They found that cardiac cells emerge rapidly during gastrulation and follow distinct paths to form the heart's pumping chambers and atria.
Yōni.Fit demonstrated significant reduction in 12-hour pad weights spanning seven days compared to the control device, highlighting its superior performance. The study showed mild to moderate adverse events, but no serious ones.
This study examines associations between structural and social determinants of health with mortality in Black adults, finding that African genetic ancestry persists as a factor despite adjustment. The findings support the hypothesis that addressing these factors is crucial for eliminating health disparities.
FibroFind's patented Precision Cut Tissue Slice (PCTS) platform preserves the architecture and function of both healthy and diseased human tissue, providing unparalleled translational accuracy. The acquisition is expected to scale FibroFind's reach across therapeutic areas and deepen its impact in pre-clinical drug development.
Prof. Netta Barak-Corren has been selected for the ERC Ambassadors program and received a Starting Grant to launch EmpiriCon, a pioneering project addressing the lack of empirical grounding in constitutional law. Her research aims to improve constitutional decision-making with rigorous, empirical work.
SWORD accelerates robotics development by reducing manual coding required for complex applications, integrating CAD with open-source ROS tools to streamline automation. The software models, plans, and executes automation in a user-friendly environment.
A study published in Behavior Therapy shows that a peer support program provides 'rapid relief of symptoms' and 'significant clinical improvement' to new moms struggling with postpartum depression. The program, Alma, pairs new and expectant moms with trained peers who have experienced similar mental health challenges.
Researchers used massive simulations to study galactic-type turbulence, finding that magnetic fields alter energy cascades and suppress small-scale motions. The findings could reshape our understanding of the Galaxy's turbulent structure and its impact on space weather.
Researchers at the Center for Genomic Regulation discovered a nine-letter microexon in DAAM1 exclusively in neurons that is critical for neuronal development and memory. Deleting this microexon in mice resulted in reduced learning spines and impaired memory function, with animals remembering roughly 40% less in standard memory tasks.
An international team of scientists has mapped the entire genome of a northern white rhino, paving the way for stem cell-based reproduction. The complete genome can be used to analyze the health of previously developed northern white rhinoceros stem cells and may eventually generate sperm and eggs to yield new rhinos.
Researchers discovered that trees close their stomata earlier than previously thought, prioritizing growth over photosynthesis during drought. This finding has implications for carbon sequestration and climate models, suggesting that trees may absorb less CO2 from the atmosphere during droughts.
A recent study published in PNAS Nexus has found that 5G exposure does not alter gene expression and methylation profiles in human skin cells. The researchers used advanced equipment to control for temperature, which was previously cited as a potential cause of adverse effects.
A global survey found a significant disconnect between physicians' and patients' perceptions of obesity causes and treatment goals. Physicians tend to attribute obesity to behavioral causes, while patients cite biological factors as the primary cause.
Professor Chao Xiang has been honoured with the 2025 Croucher Tak Wah Mak Innovation Award for his pioneering research in silicon photonics. His work on integrating lasers for advanced photonic integrated circuits shows significant improvements in sensor accuracy, communication system bandwidth, and energy efficiency.
A new study from the University of Surrey and Université du Québec à Montréal found that controlling coaching styles disrupt athletes' physical and psychological strain. Autonomy-supportive coaches boost mental resilience, while controlling tactics lead to acute stress and burnout.
Researchers found that hormone fluctuations during the mouse estrous cycle impact the shape and behavior of hippocampal neurons. The study suggests that sex hormones influence cognitive functions like memory and learning.
Researchers have identified dynamin 1 (DNM1) as a critical factor driving ovarian cancer metastasis. By inhibiting DNM1, aggressive cancer cells can be reduced in their ability to migrate and spread. The study provides promising new directions for targeted treatment strategies against this aggressive disease.
In C. elegans, researchers found a unique branching of PVD neurons in males that influences their mating behavior. This discovery reveals a previously unknown sex-specific difference in the structure of a single neuron, which also affects male coordination and speed.
Dr. Yehezkel Ben-Ari's Neuroarcheology framework links developmental mechanisms to disorders, offering new hope for previously untreatable conditions. His groundbreaking work has transformed our understanding of brain development and malfunctions.
Researchers find watercourse meeting sub-ice-shelf ocean cavity up close, with temperature and salinity analysis revealing it's a calm body of water primarily fed by sea. The study also reveals that the watercourse fluctuates greatly over time, with flood events occurring approximately every ten years.
A new deep learning model, ENDNet, significantly enhances subgraph matching accuracy by identifying and neutralizing extra nodes that interfere with the matching process. This improves performance in pattern recognition tasks across various fields, including drug discovery and natural language processing.
Five individuals have been recognized for their exceptional dedication to advancing the field of sleep medicine, with a focus on research, education, advocacy, and clinical care. The award recipients include Dr. Carol Rosen, Dr. Reena Mehra, Dr. Ilene Rosen, Dr. Nathaniel Watson, and Dr. Dennis Hwang.
George Mason University's Christan Coogle received funding to support Quality for All events for early childhood educators serving children with disabilities. The events brought together over 150 attendees across the Commonwealth, who valued resources and connections.
A Tel Aviv University study tracked 579 soldiers drafted into an IDF infantry brigade and found a sharp rise in post-traumatic symptoms after discharge, even outside of combat situations. The percentage of soldiers reporting multiple PTSD symptoms increased accordingly as service progressed.
A new computer model simulates magnetism and turbulence in the interstellar medium, providing unprecedented detail on the Milky Way Galaxy's overall magnetic field. The model also helps understand star formation and the propagation of cosmic rays, offering insights into astrophysical phenomenon.
A new study identified six distinct breast tissue patterns associated with an increased risk of invasive breast cancer, particularly among Black women. The radiomic phenotypes may help predict the likelihood of false-negative mammograms or interval cancer diagnoses.
A propensity score matching analysis reveals that video-assisted thoracoscopy with two-lung ventilation and CO2 insufflation in primary spontaneous pneumothorax does not increase the risk of recurrence and instead reduces anesthesia time.
A comprehensive review article synthesizes decades of research on stress hormone systems in primate brains, revealing key differences between rodents and primates. The findings highlight the importance of considering anatomical differences when developing treatments for stress-related psychiatric disorders.
A new study found that a simple oral swab test can increase IVF success rates by identifying the best hormone treatment for each woman based on her genetic profile. The test, developed by researchers at Lund University, shows promise in reducing costs and increasing pregnancies.
A new study published in the European Journal of Preventive Cardiology found that flavan-3-ols in tea and dark chocolate can reduce blood pressure readings. Regular consumption of these compounds was shown to improve blood vessel function, benefiting cardiovascular health.
The USPSTF recommends early, universal screening for syphilis infection during pregnancy to prevent congenital syphilis. Untreated syphilis can cause premature birth, low birth weight, and stillbirth in the fetus.
Researchers found consistent differences in maternal behaviors among wild Sumatran orangutan mothers, even after controlling for environmental factors. These variations impacted how infants learn skills and navigate dense canopies.
Chinese researchers have identified an insect predator using tools to exploit the collective defenses of social insects. The assassin bug, Pahabengkakia piliceps, weaponizes resin from stingless bee nests to lure bees into its optimal hunting position.
GOALL-epitaxy successfully stabilizes artificially designed metastable states in transition metal oxides. The method combines atomic-layer-by-layer deposition and high-intensity oxidation for high-temperature superconductivity, ferromagnetism, and other strongly correlated electronic systems.
Researchers have developed an innovative achromatic metasurface waveguide that eliminates chromatic dispersion and offers improved image clarity. The single-layer design simplifies manufacturing while enhancing system performance compared to traditional multi-layer waveguides.
Scientists create colorful replica of famous statue smaller than human hair using new 3D printing method. The microscale technique uses lasers to cure individual pixels and can produce multiple colors on demand.
The Institute for Nanoscience at NRL hosted its annual proposal planning meeting to foster intellectual curiosity and build connections among researchers, with a focus on building impactful proposals that could lead to breakthroughs. The event showcased successful project outcomes, including publications, patents, and transition efforts.
A new study by Yale researchers found that nasal vaccine boosters can trigger strong immune defenses in the respiratory tract, even without adjuvants. The 'prime and spike' approach jumpstarts immune response in the respiratory system, offering a potential safer alternative to traditional vaccines.
A landmark study by Prof. Yong Sik Ok charts biochar's global market potential as a carbon-negative technology aligned with ESG goals, UN SDGs, and Net Zero pathways. The study provides actionable guidance for governments, industry leaders, and research institutions to integrate biochar into their climate portfolios.
Researchers have discovered a zinc-based metal-organic framework (MOF) that efficiently captures CO2 while resisting interference from water. The study reveals the unique adaptability of CALF-20 under varying conditions, making it a promising solution for industrial carbon capture
HKUMed has developed the TRICH score, a clinical tool that helps physicians identify ICH patients who need early triple anti-hypertensive medication. A separate study investigates the use of telemedicine for hypertension management in ICH patients to enhance patient care.
Researchers developed a method to produce tissues with controlled cellular organization, mimicking human tissue structure. The technique uses light-based 3D printing to create microgels with tailored internal architectures, enabling precise control of cell growth and behavior.
Researchers at the University of Turku developed a simple, eco-friendly approach to fabricate optical microcavities, allowing for precise study of polaritons and potential applications in ultra-efficient lasers and quantum optics. This innovation makes quantum and photonics research more accessible and energy-efficient.
A review of 151 studies found that symptom invalidation can cause emotional states like self-doubt and shame, as well as behavioral changes such as avoiding medical care. The study recommends that healthcare providers validate patients' experiences, even in cases where a clear diagnosis cannot be made.
The University of Texas at Arlington researcher Yunyao Li has been selected by NASA to develop a system that provides early warnings of hazardous air pollution from wildfires. The project aims to enhance wildfire air quality forecasting capabilities and develop tools for decision-making processes related to health management.
A recent study published in Clinical Nutrition has found that including dairy in a veggie diet can help control blood sugar levels better than a plant-only diet. The study, which included 30 participants, showed that those following the lacto-vegetarian diet had lower average blood sugar levels compared to those on the vegan diet.
SYNT-101 successfully redirects nutrient absorption to the lower intestine, promoting satiety and metabolic balance. The study demonstrated strong safety and tolerability profiles, as well as control of hunger and weight loss.
A recent study on plant beetleweed reveals that it can have multiple chromosome complements, known as cytotypes, which previously were thought to be mutually exclusive. This finding challenges the notion that different species with distinct chromosome numbers cannot coexist.
DiffInvex identifies evolutionary shifts in driver gene repertoires during tumorigenesis and chemotherapy, pinpointing mutational escape routes that let cancers resist treatment. The framework reveals which genes may ignite resistance to anticancer drugs, suggesting a core circuitry boosting strategy.
Researchers develop new recycling concept using fatty acids to extract silver from electronic waste, making it financially viable. The process uses light and diluted hydrogen peroxide, resulting in a sustainable separation method.
Researchers found that tirzepatide increases energy expenditure directly after treatment, while semaglutide reduces it. Both drugs aid weight loss by decreasing food intake and enhancing fat oxidation.
The University of Utah is partnering with XPRIZE to improve healthy aging through a 7-year, $101 million global competition. The partnership aims to validate the science of competing teams working towards extending health spans for aging populations.
The research paper proposes a novel motion coordination framework based on multi-task prioritization and null-space projection for physically constrained quadruped manipulators. The framework adapts to different tasks by executing optimal motion while meeting physical constraints and enhancing manipulability.
Researchers have created a library of genetically engineered fruit flies linked to individual neurons in the nerve cord to characterize the circuits controlling wing motion. The study provides a resource for studying motor control of wing movements and courtship behaviors.
A novel needle-free reagent injection method has been developed using electrically induced microbubbles to improve the depth of reagent injection. The system reflects shock waves through microbubble dynamics, resulting in increased perforation ability and deeper wound expansion. This technique holds promise for future optimization and ...
The release of long-read sequencing datasets for two Kids First studies provides a fuller understanding of how genetics contributes to childhood cancers and congenital disorders. The datasets include improved genome assembly capabilities, facilitating variant discovery and potential targeted therapy development.
Researchers explore emerging technologies like Kerecis and NovoSorb BTM, which integrate antimicrobial properties into dermal substitutes. The review highlights the need for integrated antimicrobial agents to reduce antibiotic reliance and promote scarless healing.
Leading LLMs like ChatGPT and DeepSeek consistently produce broader conclusions than original texts, with six models systematically exaggerating claims. Researchers recommend using LLMs with lower 'temperature' and enforcing indirect reporting to improve accuracy.
Researchers found that OA cartilage lacks the normal bivalency of repressive and activating histone marks, leading to excessive activation of hypertrophic genes. This results in cartilage breakdown and degeneration. The study provides a potential therapeutic strategy to halt OA progression by targeting epigenetic enzyme KDM6B.
Researchers developed a dual-laser Brillouin optical correlation-domain reflectometry system that measures strain and temperature along an optical fiber without costly GHz equipment. The setup recorded Brillouin gain spectra at only about 200 MHz, over 50 times lower than the usual 11 GHz band.
Dr. Charney will retire at the end of his current term on June 30; Eric J. Nestler, MD, PhD, appointed interim dean. Under his leadership, the Icahn School of Medicine advanced its reputation as an international leader in biomedical education and research.
Generative AI agents powered by large language models meet three conditions of free will: goal-directed agency, genuine choices, and control over actions. Experts warn that as AI gains more power and freedom, moral responsibility may shift from developers to the AI agents themselves.
Researchers created a new type of insect cyborg that can navigate autonomously using UV light to guide movement, preserving sensory organs and maintaining consistent control. The system outperformed traditional methods in tests, with 94% of cyborg insects escaping a maze-like environment compared to just 24% of normal cockroaches.
Empa researchers have developed a bio-based, biodegradable material from fungal mycelium that avoids chemical processing. The material has versatile functional properties, including emulsification capabilities, and is suitable for various applications. Its biodegradability makes it an attractive alternative to traditional materials.
A new robot designed to physically support the elderly and prevent falls as they move around their homes. The Elderly Bodily Assistance Robot (E-BAR) has a set of robotic handlebars that can be used for support, with airbags that inflate instantly to catch users if they fall.
A global study found that pentoxifylline has no mortality benefit in patients with severe alcohol-associated hepatitis and acute kidney injury. The study, which included 525 patients across 20 centers from eight countries, reaffirmed previous findings that cast doubt on the efficacy of pentoxifylline in alcoholic hepatitis.
Researchers have identified conditions under which ultra-high dose rate carbon ion beams can spare normal cells while maintaining tumor control, opening new possibilities for safer radiotherapy. The study reveals a cell-sparing effect under normoxic conditions using higher linear energy transfer values.
Scientists at UC Santa Barbara and UCSF have developed a new method to design enzymes from scratch, enabling the creation of highly efficient and selective catalysts. The new approach allows for the combination of desirable properties into novel enzymes for various applications, including drug development and materials design.
Researchers developed a nomogram to predict pulmonary embolism (PE) in patients with pulmonary tuberculosis (PTB), showing strong clinical applications. The model's probabilities were close to actual values, indicating improved early diagnosis and timely intervention.
The American College of Lifestyle Medicine has integrated its first set of lifestyle medicine assessment tools into Epic electronic health records, enabling clinicians to assess patient lifestyle behaviors and readiness for change. The new tools will revolutionize team-based primary care, allowing patients to recognize and make healthi...
The University of Texas at Arlington offers pre-health students valuable hands-on experience through an innovative collaboration. Students in SCIE 4304 participate in immersive clinical simulation lab at the UTA Smart Hospital, developing rudimentary clinical skills and overcoming imposter syndrome.
Researchers at NYU Tandon School of Engineering identified a crucial role for the dorsolateral prefrontal cortex in mapping sounds to meaning, shedding light on the neural dynamics underlying word retrieval. The study's findings have significant implications for both neuroscience and clinical interventions.
A new study published in Aging (Aging-US) Volume 17, Issue 4 has found that the drug buthionine sulfoximine (BSO) produces similar reductions in fat mass and weight gain as the sulfur amino acid-restricted diet. BSO may offer a practical alternative to difficult-to-maintain diets for treating obesity.
A prospective clinical study found that early chest tube removal (≤3 days post-insertion) is feasible with comparable complication rates and interventions to late tube removal. The study's results support the implementation of an early removal protocol in high-volume trauma centers.
A new study presents an integrated model that evaluates flood risks to people's life and property in the lower Yellow River under various floodplain management modes. The model accurately simulates highly sediment-laden floods and assesses vulnerability to extreme flooding.
Researchers at Wayne State University are developing a new treatment to prevent diabetic corneal complications, which can lead to vision loss and poor healing. The project combines two naturally occurring peptides to target inflammation, delayed healing, and nerve degeneration.
Breast cancer remains a significant health challenge worldwide, with nanotechnology offering a ray of hope. Nanoparticles improve diagnostic imaging, biomarker detection, and therapy by enhancing drug solubility, stability, and targeted delivery.
Researchers found that x-ray sterilization effectiveness differs depending on dose rate and bacterial nutrient conditions. Long-term low-dose irradiation was more effective in nutrient-poor environments, while short-term high-dose irradiation achieved higher efficiency in nutrient-rich environments.
Researchers have discovered a remarkable new 506-million-year-old predator called Mosura fentoni from the Burgess Shale of Canada. The species has a unique body region made up of multiple segments at its back end, similar to modern groups like horseshoe crabs and insects. The discovery provides key insight into ancestral traits for art...
This study analyzed changes in IMLD disease spectrum and epidemiological characteristics in two Chinese hospitals. The most common IMLD was Wilson’s disease, which remained prevalent across all age groups.
A new study by UOC, UB, and EPFL identifies factors that encourage walking in Barcelona, but finds they can have the opposite effect depending on the neighborhood. The research provides valuable insights into pedestrian mobility and how it can be managed through targeted interventions.
Researchers found that people with multiple chronic conditions are at a significantly greater risk of developing depression. Combinations of cardiometabolic illnesses like diabetes and heart disease can more than double the likelihood of a future depression diagnosis.
This special issue highlights cutting-edge developments in subwavelength optics, including nonlinear meta-devices, chiral optical signals, and hybrid-layer data storage. Researchers explore new phenomena at the subwavelength scale, enabling enhanced imaging, sensing, and communication capabilities.
A study published in Molecular Motabolism found that prolonged water-fasting can increase inflammation and stress on the body, potentially exacerbating existing heart and vascular conditions. However, some benefits were observed, including a reduction in amyloid beta proteins associated with Alzheimer's disease.
A study reveals pharmacy care is perceived differently by diverse populations, with notable gaps in communication for patients with disabilities. The research highlights the importance of effective communication and accessible spaces for pharmacists to provide high-quality care.
A study found that vegetarians reject meat due to a complex emotion of disgust, similar to the aversion felt towards human flesh, faeces, or dog meat. The researchers also discovered that people who reject vegetables they dislike feel 'distaste', whereas those who reject meat do so due to disgust.
Researchers at Fox Chase Cancer Center found that fragmented care does not negatively impact survival outcomes for retroperitoneal sarcoma patients. Despite longer travel distances and delays between diagnosis and treatment, patients receiving nonfragmented care had equivalent overall survival rates as those with non-fragmented care.