Researchers from Zhejiang University have identified 185 YTH genes across twelve species of Rosaceae, revealing new insights into the regulatory mechanisms of N6-methyladenosine (m6A) and its impact on plant development. The study also highlights the potential role of YTH genes in mitigating chilling injury during cold storage.
Scientists from Chiba University successfully analyzed human chronic myelogenous leukemia cells using a new sample introduction system, achieving accurate elemental composition measurements without damaging the cells. The study expands the potential of ICP-MS technology for mammalian cultured cell analysis.
Scientists discovered a unique movement strategy in free-living corals that helps them navigate and migrate towards optimal light conditions. Pulsed inflation, similar to jellyfish movements, aids in self-righting, sediment rejection, and phototaxis.
A team of researchers at Johns Hopkins Medicine has developed a biomarker algorithm that can detect Barrett’s esophagus and esophageal cancer using a noninvasive method. The algorithm uses methylation patterns in genes to identify biomarkers, achieving an AUC of nearly 0.97 in distinguishing healthy tissue from esophageal cancer.
Researchers used EEG to map brain activity in response to hot and cold temperatures, finding that both invoke similar activity patterns in overlapping brain regions. The study could lead to more objective methods for evaluating thermal comfort and reducing health risks due to ambiguous subjective evaluations.
A recent study published in JAMA Psychiatry found that medically recommended cannabis use is associated with a higher prevalence of cannabis use disorder and more frequent use among US adults. The study suggests that medically recommended cannabis may not be effective in reducing addiction risk compared to nonmedical use.
A study by Professor Jan Peters at the University of Cologne explores how virtual slot machines' design features trigger dopaminergic effects in the brain's reward system, leading to erroneous beliefs and expectations about control over outcomes and chances of winning. This can lead to continued gambling despite high losses.
A University of Barcelona team has identified a molecular mechanism that could lead to new strategies for eliminating senescent cells in cancer patients. By analyzing human senescent cells in a melanoma tumor model, the researchers found that BCL-2 family proteins play a key role in senescence survival.
Researchers at the University of Wisconsin-Madison have developed a technique using therapeutic blood clots activated by messenger RNA to treat osteoarthritis. This approach could potentially offer a more effective option than existing treatments like steroid injections or joint replacement surgeries, with the possibility of being an i...
New research reveals that increasing minimum wages is associated with decreased summer employment and hours worked by college students. Students with limited or no work experience are disproportionately affected. The study provides valuable insights into the impact of rising minimum wages on young workers' job prospects.
Combustion-related isoprene emissions from outdoor biomass burning and residential fuel use contribute substantially to the formation of wintertime secondary organic aerosols. The study found that combustion-derived isoprene accounts for 25-40% of winter SOA in northern regions.
A new study published in Environmental DNA revealed that insecticides and fungicides are the main factors affecting biodiversity in UK waters. The AI technology analyzed water and biofilm samples from 52 freshwater lakes, identifying key links between pollutants and biodiversity loss.
Researchers developed efficient tin-based catalysts for electrochemical CO2 reduction, enabling the production of high-value formic acid with improved selectivity and activity. The study's findings provide critical insights into the reaction mechanism, highlighting the importance of structural and kinetic factors in catalyst design.
A new study from UC Davis reveals a concerning decline in residents applying to pain medicine fellowship programs, with female physicians dropping 27.5%. This could lead to longer wait times and reduced treatment options for patients suffering from chronic pain.
A new study found that people with multiple sclerosis experience a significantly higher risk of perinatal mental illness compared to those with other chronic conditions. Depression and anxiety were the most common conditions reported, with half of people with MS living with a mental illness in the first year postpartum.
A trial published by The BMJ found that combining dapagliflozin with moderate calorie restriction led to higher rates of diabetes remission compared to calorie restriction alone. This study provides a practical strategy for achieving remission in patients with early type 2 diabetes.
A recent study found that long COVID is more prevalent in women than men, and the association was linked to factors such as age, pregnancy, and menopausal status. The research highlights the need for targeted drug development and improved management strategies for long COVID.
The Association for Computing Machinery (ACM) has named 55 Fellows for their transformative contributions to computing science and technology. The inductees represent a diverse range of fields, including cybersecurity, artificial intelligence, human-computer interaction, machine learning, and programming languages.
Researchers at EPFL have developed a compact electro-optic frequency comb generator using lithium tantalate, achieving 450nm spectral coverage with over 2000 comb lines. This breakthrough expands the device's bandwidth and reduces microwave power requirements, enabling practical applications in photonics.
A study by University of Illinois political scientist Rana B. Khoury found that civil organizing persisted in Syria's armed conflict, shifting to 'translocal organizations' operating in rebel-held territory and neighboring countries. These groups combined efforts by local actors with those by refugees and diaspora members.
Research led by University of Arizona researchers found that PTSD and anxiety are associated with lower levels of anti-Müllerian hormone, a marker of ovarian reserve, among women firefighters. The study suggests that mental health conditions can have a negative impact on reproductive health.
Researchers are building a quantum computer that can connect to other quantum computers via a network for secure information transfer. The team will use atoms as qubits in an experiment involving optical tweezers and highly efficient detectors.
A Japanese research team has successfully synthesized inaoside A, an α-D-ribofuranoside-type compound isolated from the edible mushroom Laetiporus cremeiporus. This achievement paves the way for further investigation into its bioactivities and potential applications in pharmaceuticals and functional foods.
UCSF researchers found that when brain cells of female mice express only a maternal X chromosome, their memory and cognitive skills deteriorate faster. This study could explain the variation in brain aging between the sexes and individual women.
A real-world multicenter study found olaparib to be effective in maintaining remission with a 75.2% 1-year progression-free survival rate. The safety profile was consistent with known adverse events, primarily anemia and nausea.
A new study found disparities in access to semaglutide based on insurance plan, job industry, sex, and other factors. Individuals with female identities, preferred provider organization coverage, and antidepressant use were more likely to start taking semaglutide compared to males or those with certain employment industries.
A national survey of 1,008 Americans found that nearly two-thirds use a device to monitor their heart health, but only one in four shares the data with their doctor. This lack of sharing can lead to delayed diagnosis and treatment, emphasizing the importance of proactive communication between patients and healthcare providers.
The study proposes a 'school within a school' approach to enable small changes that can affect entire systems. Researchers highlight the need for transformational changes to better prepare students for the age of Artificial Intelligence.
A University of Maine-led team has developed new socioeconomic indicators to holistically monitor the Maine lobster industry's resilience. The indicators, published in Marine Policy, cover coastal accessibility, operational condition, business investments, and other key components of the industry.
If the Summerville phenomenon is an earthquake light, it might be that shallow earthquakes in the area released water-soluble gases like radon or methane, which were then ignited by static electricity or rock movement. Gas detectors could potentially test this hypothesis.
Researchers at La Jolla Institute for Immunology discovered that tissue-resident memory CD8 T cells rise up to fight infections in the small intestine, using spatial transcriptomics technology. These immune cells are split between villi and crypts, with progenitor-like cells replenishing effector T cells.
Despite decreased aspirin use among adults with low and higher ASCVD risk, many patients with limited benefit to treatment continue taking aspirin. The study highlights the need for better understanding of individual risk factors to improve treatment decisions.
West Virginia University researchers Erin Brock Carlson and Scott Davidson have designed an interdisciplinary program to engage liberal arts faculty in discussions on the social, ethical and technical aspects of artificial intelligence. The program aims to support the creation or redesign of 10 courses incorporating AI, exploring its i...
Researchers found that integrating optometrists into community clinics reduces patient wait times and lower costs for the NHS. Local optician practices handle conditions like nAMD and glaucoma, delivering quality care while optimizing resources.
Researchers explore HER2-low breast cancer, a new clinical subtype that benefits from novel treatments and personalized care. Current testing methods are not always accurate, calling for better detection methods to correctly identify patients who can benefit from these new therapies.
The PUNCH mission will integrate understanding of the Sun's corona and solar wind. The constellation will deploy in polar orbit, enabling scientists to routinely see and understand the solar wind.
Researchers at Stanford University have developed a computational workflow that can design thousands of new enzymes, predict their behavior, and test their performance across multiple chemical reactions using machine learning. This breakthrough accelerates the process of creating new enzymes, which can enhance perfumes, clean laundry, ...
Researchers from Max Planck Institute for Chemistry explain how carbon nanoparticles degrade in vehicle exhaust gases, with temperatures influencing reaction pathways. The study's findings have implications for synthetic fuels production and environmental innovation.
A new tool called EpiScalp uses algorithms trained on dynamic network models to map brainwave patterns and identify hidden signs of epilepsy from a single routine EEG. This tool has ruled out 96% of false positives, cutting potential misdiagnoses among cases by nearly 70%, according to a Johns Hopkins University study.
Establishing a permanent lunar presence will depend on the use of AI, robotics, and 3D printing to adaptively respond to challenges. The moon's natural resources, such as regolith, can also reduce the need for Earth-launched supplies.
Researchers have created a detailed structural map of GABA A receptors in the human brain, revealing how they assemble and interact with drugs. The study provides new insights into treating epilepsy, anxiety, depression, and insomnia, and paves the way for customized therapies.
Limbic-predominant age-related TDP-43 encephalopathy (LATE) is a common memory disorder that can progress slower and cause less impairment of cognitive functions than other types of dementia. The new guidelines provide a first step in advancing clinical trials and treatments for this lesser-known, but common type of memory loss disorder.
Free-living mushroom coral Cycloseris cyclolites exhibits complex phototactic mobility in response to light direction. The coral migrates using rolling, sliding, or pulsing movements to navigate towards blue or white light sources.
The new tool will enhance the DLA's supply chain management capabilities, reduce operational disruptions, and bolster readiness. Quantum Research Sciences' technology will provide predictive capabilities and automate obsolescence management processes.
A groundbreaking AI model developed by researchers at Emory University accurately predicts the likelihood of blood transfusion in non-traumatic ICU patients, addressing longstanding challenges in predicting transfusion needs. The model achieved exceptional performance metrics, including an AUROC of 0.97 and an accuracy rate of 0.93.
The Aging Research and Drug Discovery Meeting (ARDD2025) will feature Nobel laureates Morten Meldal and Michael Levitt. Their groundbreaking discoveries have had a lasting impact on drug development and molecular design, highlighting the conference's pivotal role in advancing healthspan and longevity science.
A new study found that traffic-related air pollution is associated with depression in women, and this association is independent of sociodemographic and health factors. The study also suggests that menstrual cycle characteristics may mediate the relationship between TRAP exposure and depressive symptoms.
The FORSAID project aims to develop a comprehensive framework for early detection of pests and pathogens affecting European forest trees. The project will employ novel technological solutions, including remote sensing, AI modelling, and DNA barcoding, to combat harmful species in forests.
A research team from the University of Minnesota Medical School received a $1.2 million grant to study the use of TMS in addition to CBIT as a treatment for children with Tourette syndrome. The trial found that this new treatment improved brain circuits involved in tics, and the researchers hope it could lead to a future treatment option.
A groundbreaking AI tool called Moscot maps single cells in spatial tissues, enabling the observation of millions of cells simultaneously. This allows researchers to analyze complex cellular processes within entire living organs and organisms, providing new insights into diseases like diabetes.
A team of researchers has developed a theoretical model forecasting the ideal body plan of a fruit fly's early embryo, indicating that evolution might have had many optimal options. The study suggests that optimization is a key driving force in nature, with biological systems often having multiple optimal solutions for the same problem.
A new method can detect tiny amounts of SARS-CoV-2 virus in blood, stool, and saliva from patients with acute COVID-19 infections. The technology has potential for guiding treatment of long COVID and monitoring viral loads for future infectious diseases.
A study by Ohio State University researcher Nima Dahir found that Black immigrants can act as a buffer between Black and white residents, increasing the white population in neighborhoods with a high native-born Black presence. The influx of Black immigrants led to a decrease in native-born Black residents and an increase in non-Hispani...
A new study finds that excess RELMb protein in the intestine disrupts tolerance to triggering foods and increases the risk of food allergy. Inhibiting RELMb may lead to a cure or prevention of food allergy, offering a promising therapeutic approach.
Researchers at KAIST and U of Michigan developed a digital biomarker to predict symptoms of depression using smartwatch data. The technology estimates circadian rhythm disruption, which can lead to depression, anxiety, and other mental health issues.
A study of Australian tennis coaches found that women experience limited opportunities for leadership roles, exclusion within professional networks, and challenges in balancing work-life responsibilities. Only 42% of women coaches reported they would commit to coaching for over 10 years, compared to 55% of men.
A team of researchers re-examined the aftershock sequence of the 2015 Bonin Islands earthquake and found no evidence for a record-breaking deep aftershock in the lower mantle. Instead, they discovered a distribution of aftershocks compatible with a 12-kilometer olivine sliver that sheds light on how deep earthquakes can occur.
A new study led by University of Oxford suggests that plants are more likely to be eavesdroppers than altruists when tapping into underground networks. The study found that it is unlikely that plants would evolve to warn other plants of impending attacks, instead finding that plants may signal dishonestly to harm their neighbors.
Frontiers partners with WEF's Centre for Fourth Industrial Revolution to enhance visibility of scientific research and drive global solutions. Researchers will contribute to flagship reports, participate in policy events, and foster innovative solutions through interdisciplinary networks.
Furan fatty acids have been found to exist in all samples of rubber tree latex, with varying concentrations. The study identifies specific genotypes with high FuFA content, offering potential for enhanced economic value and sustainability.