Researchers used imaging mass spectrometry to map signaling molecules between organisms, discovering metabolites involved in bacterial cannibalism. SDP and SKF were found to be essential for identifying and killing genetically identical cells.
Researchers at UC San Diego School of Medicine identified a molecular mechanism making omega-3 fatty acids effective against chronic inflammation and insulin resistance in diabetes. Omega-3 fatty acids activate GPR120 receptor on macrophages, resulting in anti-inflammatory effects and improved insulin sensitivity.
Researchers at UC San Diego developed a new chip prototype called GreenDroid, which uses dark silicon to improve performance through specialized processors. The prototype delivers improved efficiency by running heavily used code in Google's Android platform, resulting in up to 7.5 times increased efficiency compared to aggressive mobil...
A team of researchers has developed a simulation to better understand the impact of sound on marine mammals like whales and dolphins. The simulation uses advanced computing and X-ray CT scanners to create a 3D virtual environment, allowing scientists to study the effects of sound on these organisms.
Researchers at UC San Diego and NEI Corporation are designing new types of lithium-ion batteries with exceptional energy density, potentially used in NASA space exploration projects and consumer applications. The goal is to create commercially useable cathode materials with high capacity and structural stability.
A team of UC San Diego researchers has created a novel map of lipid locations in a single cell, providing insights into how lipids influence disease processes. The study identified over 220 individual molecular lipid species and found that numerous lipids change in abundance once a macrophage becomes active.
A study of egg cell division has revealed an 'inside out' mechanism for chromosome separation, which could help explain reproductive problems like Down syndrome and infertility. The researchers used time-lapse microscopy to observe egg cell meiosis with high precision, discovering that chromosomes move apart by being pushed in the middle.
A team of experts is proposing a new approach to deal with the variability in behavior of nano-scale computer components by re-thinking and enhancing the role that software can play. The National Science Foundation has awarded a $10 million grant to explore 'Variability-Aware Software for Efficient Computing with Nanoscale Devices.'
Researchers have identified a new cellular communication mechanism in glioblastoma cells, which could be targeted to slow tumor growth. If blocked, this pathway may significantly reduce GBM malignancy.
A new study found that rising temperatures in Asia will slow rice production, with daily minimum temperature increases cutting yield growth rate by 10-20 percent in several locations. This could lead to food insecurity and poverty for the over three billion people who rely on rice as their staple food.
Researchers developed a proof-of-concept system that removes pedestrians from urban scenes in Google Street View, exploring how computer vision can preserve privacy in public environments. The system replaces pedestrians with an approximation of the actual background behind each pedestrian.
Babenko's fellowship will allow him to attend the European Conference on Computer Vision and work on weakly supervised learning systems for object detection and recognition. His research focuses on tackling computer vision problems with less precise labels, enabling more efficient data collection.
Researchers at UC San Diego School of Medicine identify microRNA miR-132 as the 'gas pedal' controlling uncontrolled blood vessel growth. They develop an anti-miR therapy to restore functionality to the 'brake,' halting disease progression in mouse models of cancer and retinal disorders.
A US-Mexico border program using a 35-minute behavioral intervention significantly reduced the incidence of HIV and STIs among female sex workers. The program, called Mujer Segura or Healthy Woman, was found to be cost-effective, with an estimated expense per intervention of less than $200.
A bioengineered implantable glucose sensor successfully monitored tissue glucose levels in animals for over a year, demonstrating its potential as an alternative to traditional glucose monitoring methods. The device could help people with diabetes adjust their insulin doses and reduce the risk of hypoglycemia.
Electrical activity in developing brain cells influences the choice of neurotransmitter, altering behavior. Researchers found that tweaking genetic signals can change an animal's behavior by changing the transmitters neurons make and use.
Researchers discovered a non-human sialic acid sugar in biotech drugs that can provoke a strong immune response in some individuals, worsening chronic inflammation. A simple modification to the drug-making process could solve this problem by adding human sialic acid.
NOAA has selected Scripps Institution of Oceanography, UC San Diego, to lead a new research partnership, CIMEC, to study climate change and coastal ecosystems. The institute will focus on ecosystem-based management of fisheries and continue the longstanding work of JIMO in climate and ocean sciences.
Researchers at Monash University and Scripps Institution of Oceanography developed a new mathematical scaling theory to explain the global motions of tectonic plates. The theory demonstrates that the velocities of plates and boundaries depend on subduction zone size and presence of subduction zone edges.
Researchers discovered the SRD5A3 gene mutation responsible for congenital disorders of glycosylation (CDG), which affects eye and brain development in infants. A daily dietary supplement containing dolichol, a lipid carrier, may treat the condition, which has no current treatment.
A new study by Scripps Institution of Oceanography reveals that floating glaciers produce larger icebergs than grounded cousins and behave erratically. This is the first detailed observation of a glacier transitioning from grounded to floating.
The University of California, San Diego will lead a seven-year, $9.2 million NIH grant-funded effort to study and understand the complete disease cycle of malaria in the Amazon basin. The goal is to comprehensively address the ongoing public health problem of malaria, which affects over 3 billion people worldwide.
Researchers at UC San Diego identify new signaling pathway critical for embryonic stem cells' self-propagation, finding that inhibiting this pathway reduces teratoma formation. This breakthrough enables a potential solution to the major obstacle in developing human embryonic stem cell therapies.
A landmark study in the US has compared natural orifice translumenal endoscopic surgery (NOTES) to traditional laparoscopic surgery for gallbladder removal. The trial aims to assess safety, efficacy, pain levels, and cosmetic outcomes of NOTES, which may reduce post-operative infection, hernia, scarring, and pain.
Researchers at UC San Diego discovered that the brains of humans and chickens share comparable regions for analyzing auditory inputs. The study found laminated layers of cells linked by narrow columns in both species, indicating that complex cognitive functions may have evolved from ancient vertebrates.
A study by researchers at the University of California, San Diego found that older adults spent three times more time watching TV than younger adults, yet reported lower levels of positive emotion during TV viewing. This suggests a need to increase awareness of alternative activities and reduce barriers to social engagement.
A study published in Neuron reveals that the loss of Nna proteins causes mitochondrial dysfunction, leading to severe cell death in mice and fly models. Researchers believe this discovery could provide insights into human neurodegenerative disorders like Parkinson's disease.
A new software called SleepServer created by UC San Diego computer scientists reduces energy consumption on enterprise PCs by an average of 60 percent. The software maintains connectivity and responds to applications even when the PCs are in low-power sleep mode, enabling them to work while they sleep.
A four-year clinical trial will investigate the effects of weight loss and increased physical activity on quality of life and co-existing medical conditions in overweight breast cancer survivors. The study aims to reduce breast cancer recurrence risk and improve psychosocial problems.
Researchers found that adding nucleic acid testing to HIV screening can detect the presence of HIV earlier, increasing detection yield by 23%. A large majority of study participants received negative test results via automated phone or internet systems. The findings suggest that such programs can help control the HIV epidemic.
Researchers at the University of California, San Diego School of Medicine found that removing three key inhibitory molecules from myelin did not significantly improve axon regeneration in damaged spinal cords. The study suggests that successful regeneration will require a combination of many approaches and techniques.
Fatal medication errors peak in July among new medical residents, especially in counties with teaching hospitals. Increased supervision and education on medication safety may reduce these errors.
Scientists identified a novel enzyme, PEAK1, that regulates cell proliferation, shape and migration. The discovery may provide a new target for future anti-cancer therapies.
Researchers have identified a genetic cause of inherited conditions causing severe fetal abnormalities, potentially leading to treatments for related disorders. The study found that the faulty gene stops cells' 'antennae' from transmitting information.
Researchers found zebrafish possess an enzyme linked to cortisol, which may aid in understanding its function in the human brain. The discovery could provide new avenues for investigating diseases related to cortisol imbalance.
The US Navy has selected Scripps Institution of Oceanography to operate a new scientific research vessel, advancing science and education in the decades ahead. The Ocean Class ship will lead ocean expeditions advancing knowledge on global climate change, submarine warfare, and more.
The American Society for Microbiology will honor Scripps Institution of Oceanography pioneer Claude ZoBell's contributions to marine microbiology. The event, held on May 22, recognizes ZoBell's pioneering research career and his work laying the foundation for the field.
Researchers have developed a tiny silicon chip that can detect specific chemicals and map their location, potentially alerting emergency responders to hazardous situations. The sensor works by manipulating the shape of pores on the silicon flake to respond to specific chemical traits.
Research finds common intestinal bacteria promote tumor growth in genetically susceptible mice, but an inhibiting protein enzyme suppresses growth, increasing survival time. The study's findings could lead to a new form of treatment for familial adenomatous polyposis, a genetic condition that increases the risk of colon cancer.
Researchers identified central, unifying elements of wisdom, including its uniqueness to humans, experiential nature, and personal quality. The study provides insight into the characteristic qualities of wisdom, shedding light on its distinctiveness from intelligence and spirituality.
Researchers discovered that human embryonic stem cells (hESCs) and lineage-committed cells have drastically different epigenomic landscapes. The unique epigenome of each cell type directs the cell to interpret its genetic information differently in response to environmental factors, influencing their development and function.
Researchers propose a multi-faceted approach to avoid exceeding the 2-degree C temperature threshold, including reducing methane, hydrofluorocarbons, and other greenhouse gases. They advocate for aggressive simultaneous pursuit of strategies to stabilize CO2 concentrations and implement warming-neutral pollution laws.
Researchers found that both men and women who had higher depression scores consumed almost 12 servings of chocolate per month. Chocolate consumption was not associated with other antioxidant-rich foods or energy intake.
A study by David Victor finds that fossil-fuel subsidies undermine energy security and worsen the environment. Most subsidies are a waste of money, and their removal could provide $550 billion annually for more beneficial programs.
Researchers at University of California, San Diego developed a new solar concentrator design that minimizes materials, alignment, and assembly costs. The innovative system collects sunlight with thousands of small lenses imprinted on a common sheet, reducing the need for individual photovoltaic cells.
Researchers found that mice lacking the FIH protein process fat differently, resulting in improved health outcomes on a high-fat diet. The lean mice exhibit enhanced insulin sensitivity and lower cholesterol levels compared to their normal littermates.
Researchers discovered a network of genes responsible for initiating and managing primary cilia formation. The study may lead to new therapies for ciliopathies, a group of genetic diseases caused by defects in primary cilia function or structure.
Researchers at the University of California - San Diego developed a smart delivery system capable of delivering lauric-acid-filled nano-scale bombs directly to skin-dwelling bacteria that cause common acne. This treatment has the potential to avoid undesirable side effects associated with current treatments.
Researchers investigating lunar reflector performance report decreased signal strength during full moon, suggesting dust may be a culprit. The issue arises from uneven heating of glass cubes left behind by Apollo astronauts, which distorts the shape of reflected laser pulses.
Researchers found truncated peptides form active ion channels causing cell death and memory loss, contradicting previous effective treatments. A new approach aims to control these ion channels for an effective treatment.