Researchers have identified a new cellular communication mechanism in glioblastoma cells, which could be targeted to slow tumor growth. If blocked, this pathway may significantly reduce GBM malignancy.
A new study found that childhood abuse can lead to a weakened immune system later in life, with participants who experienced adverse experiences showing higher levels of stress markers. Additionally, caregivers who had been abused as children showed significantly shorter telomere length than non-caregivers.
Researchers at SUNY Downstate Medical Center have identified proteins (Ligatin, MCT-1 and DENR) that can enhance the progression of viruses and cancer cells by promoting eIF2-independent translation initiation. This novel mechanism is a potential target for therapeutic inhibition to counteract viral infections.
New research finds that childhood trauma can lead to inflammation and cell aging, shortening lifespan by seven to 15 years. Adults who experienced childhood adversity continue to be at greater risk for health consequences even in later life.
Inflammation-causing cells in fat tissue contribute to the link between obesity and diabetes. Researchers found that macrophages produce cytokines that lead to insulin resistance. Losing weight reduced macrophage presence and risk of complications.
Research shows that childhood poverty and social isolation can lead to heightened reactivity, increasing the risk of heart disease later on. A study examining 212 adolescents found that those from lower socioeconomic status had stiffer arteries and higher blood pressure.
A study by Gail McGuire found that women are disadvantaged in informal networks developed at work, which can hinder future career goals. Women receive more social support from female colleagues, but this has limited career pay-off.