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Science News for June 23, 2010


Ear tubes appear safe in children with cochlear implants, UAB researchers say

Researchers at the University of Alabama at Birmingham found that ear tubes can be safely installed in children with cochlear implants to help clear up infections. The study showed no adverse impact on child health and hearing outcomes, allowing for proper management of ear tubes before cochlear implantation.

SourceUniversity of Alabama at Birmingham·JournalArchives of Otolaryngology - Head and Neck Surgery·DateJun 23, 2010

Early and aggressive arthritis treatment recommended

Researchers found that patients treated with early combination disease-modifying antirheumatic drug therapy had less radiographic damage in small joints, even after 11 years. Early and aggressive treatment achieves excellent results for most patients, especially those who achieve strict remission at 1 year.

SourceBMC (BioMed Central)·JournalArthritis Research & Therapy·DateJun 23, 2010

The language of RNA decoded: Study reveals new function for pseudogenes and noncoding RNAs

A new study reveals that thousands of noncoding RNAs have a regulatory role independent of their protein-coding function, communicating with each other to influence cellular microRNAs. This discovery introduces 'competitive endogenous RNAs' and doubles the size of the functional genome, offering new insights into cancer and human disease.

CIMIT announces $3 million in medical research grants

CIMIT has awarded over $3 million in seed grants to support innovative medical research projects targeting brain injuries, pain management and improving care for wounded warriors. The selected projects aim to accelerate medical innovation and improve patient care through novel approaches and clinical systems.

SourceCIMIT·DateJun 23, 2010

Jetting off without the jet lag

A new study has identified a key role for adrenal glucocorticoids in resetting the internal body clock, a finding that could lead to new treatments for jet lag. The research also highlights the importance of timing and location in regulating circadian rhythms.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateJun 23, 2010

JCI table of contents: June 23, 2010

Researchers have found that modulating the adrenal gland's production of glucocorticoid hormones can regulate the resetting of the internal body clock, providing a new potential therapy for jet lag. This discovery also has implications for those who suffer from rotating shift work and its associated health problems.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateJun 23, 2010

Every fifth scientific article now available openly on the internet

A recent study found that 20.4% of peer-reviewed articles published in 2008 were freely available online, with the highest share in Earth Sciences (33%) and the lowest in Chemistry (13%). The study suggests that author-posted manuscript copies dominate certain fields, while OA journals are more common in Medicine and Biochemistry.

SourcePLOS·JournalPLOS ONE·DateJun 23, 2010

Subchondral bone changes contribute to cartilage damage and loss

A recent study found that subchondral bone mineral density positively predicts cartilage defect development at the medial tibial site, but not cartilage loss. Researchers believe subchondral bone changes and loss of cartilage contribute to osteoarthritis, a condition affecting millions worldwide.

SourceWiley·JournalArthritis & Rheumatism·DateJun 23, 2010

Gap in preventive care exists among Latinos, study shows

Researchers at UCLA found that Latinos from Central and South America and those from Mexico are more likely to experience low levels of preventive care, with lower rates of basic screenings such as colorectal cancer screening and influenza vaccinations. Addressing this gap could help reduce healthcare costs by promoting targeted interv...

SourceUniversity of California - Los Angeles·JournalAmerican Journal of Preventive Medicine·DateJun 23, 2010

Timely technology sees tiny transitions

A new technique developed by Rice University researchers can detect the movement of single molecules over hours using plasmonic properties of nanoparticles. This method is label-free and permanent, enabling the tracking of molecular interactions at the single-molecule limit.

Separation between Neanderthal and Homo sapiens might have occurred 500,000 years earlier

A study analyzing ancient teeth found that it's possible to correctly identify species with a success rate ranging from 60% to 80%. Computer simulation was used to observe the effects of environmental changes on morphology of the teeth. The research suggests that the common ancestor of Neanderthals and Homo sapiens may still be unknown.

SourceUniversity of Granada·JournalJournal of Human Evolution·DateJun 23, 2010

Rice wins $3.7 million for cancer research

Rice University researchers, led by John McDevitt, have been awarded $3.7 million to develop a cost-effective Bio-Nano-Chip that can detect early warning signs of disease. The technology has the potential to cut treatment time and costs, enabling emergency medical technicians to perform tests at home or in an ambulance.

Swiss media likely to twist positive health messages

A study published in BMC Research Notes found that public health campaigns in Swiss media frequently featured negative threats despite a focus on positive, gain-framed messages. Regional newspapers played a crucial role in reporting the campaign, producing more detailed articles than other media outlets.

SourceBMC (BioMed Central)·JournalBMC Research Notes·DateJun 23, 2010

Selective estrogen targeting to protect the heart and blood vessels

Researchers discovered an estrogen-dendrimer conjugate that selectively targets heart-protective pathways in mice, promoting cardiovascular protection without stimulating uterine enlargement or breast cancer growth. The findings pave the way for potential therapeutic interventions targeting non-nuclear estrogen receptors.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateJun 23, 2010