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Science News for September 11, 2025


Academia Sinica researchers engineer synthetic carbon fixation cycle to boost photosynthesis efficiency in plants

Researchers at Academia Sinica have engineered a synthetic carbon fixation cycle to improve photosynthetic performance and accelerate plant growth and lipid biosynthesis. The McG cycle pathway achieves a 50% increase in carbon fixation efficiency, along with enhanced biomass accumulation and lipid content.

SourceAcademia Sinica·JournalScience·TypeExperimental study·DateSep 11, 2025

Colorectal cancer cells drive collagen production in cancer-associated fibroblasts via TGF-β1-induced de novo glycine synthesis: PHGDH as a promising therapeutic target

Researchers found that colorectal cancer cells stimulate cancer-associated fibroblasts to produce collagen through TGF-β1-induced de novo glycine synthesis. PHGDH is identified as a potential therapeutic target for treating colorectal cancer.

Cu2+-coordinated NLG919: A drug delivery nanoplatform to activate antitumor immunity via inducing immunogenic cell death and inhibiting indoleamine 2,3-dioxygenase-1

The Cu2+-coordinated NLG919 nanoplatform induces immunogenic cell death and inhibits indoleamine 2,3-dioxygenase-1 to activate antitumor immunity. It also reverses the tumor microenvironment by blocking IDO1 inhibition.

SourceSichuan International Medical Exchange and Promotion Association·JournalMedComm – Biomaterials and Applications·DateSep 11, 2025

Artificial intelligence‑assisted conductive hydrogel dressings for refractory wounds monitoring

Researchers developed AI-assisted conductive hydrogel dressings for intelligent wound monitoring, combining real-time physiological signal detection with artificial intelligence. The smart dressings offer personalized wound care and have the potential to bring hope to millions suffering from chronic wounds.

SourceShanghai Jiao Tong University Journal Center·JournalNano-Micro Letters·TypeExperimental study·DateSep 11, 2025

Scalable fabrication of methylammonium‑free wide‑bandgap perovskite solar cells by blade coating in ambient air

Researchers have developed a novel, MA-free ink that enables the scalable fabrication of wide-bandgap perovskite solar cells using blade coating in ambient air. The resulting cells achieve certified 23% efficiency, one of the highest values reported for an MA-free film.

SourceShanghai Jiao Tong University Journal Center·JournalNano-Micro Letters·TypeExperimental study·DateSep 11, 2025

US COVID-19 school closures were not cost-effective, but other non-pharmaceutical interventions were, new study finds

A new study found that US school closures imposed significant economic losses while other measures like mask mandates and testing proved more effective at controlling the virus. The research suggests rapid deployment of these interventions could have saved over 100,000 lives and cut total US impact from £3.7 trillion to £1.5 trillion.

SourceUniversity of Oxford·JournalBMC Global and Public Health·TypeData/statistical analysis·DateSep 11, 2025

Cataract surgery on both eyes can be carried out safely and effectively in one go

Two new studies show that cataract surgery on both eyes can be safe and effective for most patients to perform immediately after surgery, with high rates of independence and minimal need for assistance. Patients receiving multifocal lenses achieved the best visual outcomes, with over 85% achieving 20/20 vision or better.

AI tools fall short in predicting suicide, study finds

A systematic review of 53 studies found that machine learning algorithms for predicting suicidal behavior have low accuracy. The algorithms were poor at identifying individuals who would later self-harm or die by suicide, while exceling in detecting those who would not.

SourcePLOS·JournalPLOS Medicine·TypeSystematic review·DateSep 11, 2025

Recyclable luminescent solar concentrator from lead-free perovskite derivative

Scientists have developed a recyclable luminescent solar concentrator (LSC) using a lead-free perovskite derivative, which absorbs sunlight and emits fluorescence to generate electricity. The LSC exhibits high power conversion and optical efficiencies, as well as self-healing and reversible transition properties.

Turbulence with a twist

UC San Diego researchers Guru K. Jayasingh and Nigel Goldenfeld have predicted that a pipe's curvature can lead to a discontinuous turbulent transition beyond a critical flow velocity. This phenomenon is mathematically equivalent to the freezing of water, leveraging tricritical directed percolation theory.

SourceUniversity of California - San Diego·JournalPhysical Review Letters·TypeData/statistical analysis·DateSep 11, 2025

City of Hope Research Spotlight, August 2025

Researchers at City of Hope have made significant breakthroughs in understanding genetic mutations, identifying a potential new treatment for acute myeloid leukemia, and uncovering the role of DNA methylation in preventing tangle-prone sequences that can lead to aging and cancer. The study's findings hold promise for developing new dia...

Cellular quality control in humans decoded

Researchers have developed a system to selectively switch off the key molecule of NMD, allowing them to observe its function in human cells with unprecedented precision. The study reveals that NMD not only prevents errors but also acts as an important regulator of gene activity.

SourceUniversity of Cologne·JournalMolecular Cell·TypeExperimental study·DateSep 11, 2025

Lasker Foundation announces 2025 Lasker Award winners

The Lasker Foundation has announced the 2025 Lasker Award winners, recognizing Dirk Görlich and Steven L. McKnight for their discovery of low-complexity domains within protein sequences. Michael J. Welsh, Jesús González, and Paul A. Negulescu have also been honored for developing a novel triple-drug combination therapy for cystic fibro...

Multifaceted benefits of ginseng and its extracts: a brief review of immunomodulation, quality of life improvement, and antitumor potential

Ginseng exhibits multifaceted benefits through its immunomodulatory properties, improving quality of life by alleviating chronic fatigue and cognitive decline. Its extracts also show promise in inhibiting tumor growth and metastasis, suggesting potential as an adjunct therapy in oncology.

SourceXia & He Publishing Inc.·JournalFuture Integrative Medicine·DateSep 11, 2025

Ohio State scientists advance focus on nuclear propulsion

Researchers at Ohio State University are developing a new nuclear thermal propulsion system, called the centrifugal nuclear thermal rocket (CNTR), which could potentially double an engine's efficiency. The CNTR concept aims to improve rocket performance while minimizing risk and enabling faster travel times to distant destinations.

SourceOhio State University·JournalActa Astronautica·DateSep 11, 2025

Adolescent ADHD symptoms affect adult income indirectly through education and mental health

A study by the University of Oulu found that adolescent ADHD symptoms affect adult income indirectly, through education and other psychiatric disorders. The study revealed a 25% decrease in incomes among individuals with both ADHD and ODD, highlighting the importance of preventive services and investments in education and mental health.

SourceUniversity of Oulu, Finland·JournalEuropean Child & Adolescent Psychiatry·DateSep 11, 2025

The percentage of women who went without a Pap smear for cervical cancer screening increased following the COVID-19 pandemic, from 19% in 2019 to 26% in 2022

A significant increase in Pap smear avoidance was observed among US women following the COVID-19 pandemic, with 26% of women going without screening in 2022 compared to 19% in 2019. This trend was particularly pronounced among African American women, highlighting the need for targeted health interventions.

SourcePLOS·JournalPLOS Global Public Health·DateSep 11, 2025

NEW STUDY: Across eight Amazon countries, forests on Indigenous lands reduce spread of 27 diseases – From respiratory ailments to illnesses spread by insects, animals

Research reveals that municipalities near healthy forests face lower risk from cardiovascular and respiratory diseases. The study, led by the International Union for Conservation of Nature, found that Indigenous forests bring health benefits to millions and can prevent millions of cases of respiratory and cardiovascular infections each...

SourceInternational Union for Conservation of Nature·JournalCommunications Earth & Environment·TypeData/statistical analysis·DateSep 11, 2025

Creating user personas to represent the needs of dementia caregivers supporting medication management at home

A recent study developed three distinct caregiver personas: Checklist Cheryl, Social Sam, and Responsive Rhonda. These personas embody different approaches to medication management, varying in organization, technology use, collaboration, and response to challenges. The study found that caregivers employ diverse strategies blending tech...

SourceRegenstrief Institute·JournalJMIR Aging·DateSep 11, 2025

A practical tool to support harmonization and quality improvement in vitamin D testing

A new study published in Clinical Chemistry and Laboratory Medicine has developed a practical tool to support harmonization and quality improvement in vitamin D testing. The multicentre study evaluates the measurement uncertainty of various 25-(OH)D assays and their ability to detect physiologically relevant changes over time.

SourceInternational Osteoporosis Foundation·JournalClinical Chemistry and Laboratory Medicine (CCLM)·TypeExperimental study·DateSep 11, 2025

Study reveals new evidence, cost savings for common treatments for opioid use disorder in mothers and infants

The study found that buprenorphine produced the greatest health gains and cost savings for mothers and infants compared to alternative treatments. Buprenorphine was shown to be protective against critical outcomes such as preterm birth and low birth weight, despite its association with neonatal opioid withdrawal syndrome.

SourceVanderbilt University Medical Center·JournalJAMA Pediatrics·DateSep 11, 2025

Researchers revive the pinhole camera for next-gen infrared imaging

Researchers have developed a high-performance mid-infrared imaging system without lenses, capturing clear pictures over large distances and in low light. The system uses an optical pinhole inside a nonlinear crystal to form an image, which is then converted into visible light, allowing for distortion-free and large-depth imaging.

SourceOptica·JournalOptica·DateSep 11, 2025

Volcanic emissions of reactive sulfur gases may have shaped early mars climate, making it more hospitable to life

A new study suggests that volcanic activity on early Mars emitted sulfur gases, creating a greenhouse effect and making the planet's climate more hospitable to life. The research found high concentrations of chemically reduced forms of sulfur, which are highly reactive and could have induced a hazy environment.

SourceUniversity of Texas at Austin·JournalScience Advances·DateSep 11, 2025

Invasive plants are rapidly changing the tropics

A study led by Danish researchers highlights the rapid spread of invasive plant species in tropical regions, altering food chains and damaging traditional ecosystem services. The phenomenon is exacerbated by climate change, leading to widespread ecosystem collapse and degradation.

SourceAarhus University·TypeSystematic review·DateSep 11, 2025

Portable light-based brain monitor shows promise for dementia diagnosis

Researchers have demonstrated a portable, noninvasive technology that can detect metabolic changes linked to Alzheimer's disease by measuring cytochrome c oxidase activity. The study found that including oxCCO measures improved the ability of the brain-monitoring tool to capture clinically relevant brain changes.

SourceSPIE--International Society for Optics and Photonics·JournalJournal of Biomedical Optics·DateSep 11, 2025

Key diagnostic system for ITER reactor nears completion

A sophisticated neutron flux diagnostic system will gather knowledge of plasma and power released in nuclear reactions at ITER. The High Resolution Neutron Spectrometer (HRNS) measures both neutron number and energies, providing information on fuel composition, ion temperature, and combustion quality.

Research exposes far-reaching toll of financial hardship on patients with cancer

Researchers found a significant association between financial toxicity and worse emotional and physical well-being among cancer patients. Financial toxicity, which includes stress, expense, and instability caused by healthcare costs, can have far-reaching consequences, including psychological distress and lower quality of life.

SourceUniversity of Chicago Medical Center·JournalJCO Oncology Practice·TypeSurvey·DateSep 11, 2025

Who benefits from digital well-being apps? – New study sheds light on potential user archetypes

A new study found that individuals with lower life satisfaction and daily challenges were more likely to use digital well-being apps, but app engagement was highest among those with higher life satisfaction. The study identified three user archetypes: thriving nonactive users, struggling nonactive users, and active users.

SourceUniversity of Eastern Finland·JournalJournal of Medical Internet Research·DateSep 11, 2025

How nations balanced health and economy in the COVID-19 pandemic: A global review

Researchers analyzed multiple countries' performance in achieving infection control and economic recovery, highlighting the impact of risk attitudes, patience, and trust on policy decisions. Countries with high levels of trust and patience managed to limit deaths and resuming production, while those with low trust and higher risk toler...

SourceShinshu University·JournalJournal of Policy Modeling·TypeData/statistical analysis·DateSep 11, 2025

Peer-reviewed study validates Mentavi’s online ADHD diagnostic evaluation in the Journal of Clinical Psychiatry

A peer-reviewed study published in the Journal of Clinical Psychiatry validates Mentavi's online ADHD diagnostic evaluation, demonstrating its accuracy and reliability compared to traditional face-to-face clinical interviews. The study provides evidence-based support for telehealth access for adults with ADHD, addressing gaps in care c...

SourceMentavi Health·JournalJournal of Clinical Psychiatry·TypeObservational study·DateSep 11, 2025

Durham University scientists play key role in testing superconducting materials for world’s largest fusion energy project

Durham University scientists have completed one of the largest quality verification programmes on superconducting materials for the world's biggest fusion energy experiment ITER. Their findings shed light on the quality of wires and how to test them, providing crucial knowledge for scientists to make fusion energy a reality. The resear...

SourceDurham University·JournalSuperconductor Science and Technology·DateSep 11, 2025

Machine embroidery encodes skin-like tension lines in textiles, enabling mass-customizable wearables

Researchers created a machine embroidery technique that encodes fabric stretchability, allowing for unique stretch patterns and mimicking the mechanics of skin. The approach enables mass-customization at industrial scale, enabling garments to conform to individual body shapes and reduce injury risk.

SourceEstonian Research Council·JournalAdvanced Materials·TypeExperimental study·DateSep 11, 2025