Researchers found that immature neutrophils migrate into inflamed tissues upon stimulation by interferon-γ, suppressing inflammation and reducing tissue damage. In humans, these cells also produce interleukin-10, which increases in the blood of COVID-19 patients.
A new study from La Trobe University found that knee crepitus, a common symptom of grinding or clicking sounds in the knee joint, does not predict joint damage over time. In fact, those with knee crepitus showed more severe symptoms early on but did not experience worsening pain and function in the long term.
Researchers from The University of Osaka discovered that macrophages can directly engulf and digest damaged mitochondria through a process called microautophagy. This process allows lysosome-like compartments in macrophages to take in broken cell components directly, bypassing the need for digestion.
Researchers found that chronic stress triggers the release of immune cells in the brain's protective layer, contributing to depression symptoms. Blocking these cells' signaling pathway shows promise for improving behavior and alleviating depressive symptoms.
A team of researchers developed a scalable biological signal-processing framework that uses synthetic operational amplifiers to convert mixed cellular inputs into clean, orthogonal outputs. This enables precise, predictable control of complex biological systems, with applications in biomanufacturing and signal decomposition.
A recent study found that menin promotes bladder cancer malignancy by enhancing TFAP2C/β-catenin signaling, suggesting its potential as a therapeutic target and prognostic marker. Menin upregulates TFAP2C expression, which regulates β-catenin gene transcription via binding to its proximal promoter.
Researchers are collecting faeces from exotic animals at Dudley Zoo and West Midlands Safari Park to search for phages that can fight bacterial infections. The goal is to create a bio-bank of these phages to develop alternative treatments for life-threatening infections.
A team of researchers from China cloned the heat-stable RKN-resistant gene Mi-9 from Solanum arcunum accession LA2157, showing it confers heat-stable resistance to root-knot nematodes. The study demonstrates a roadmap for rapid characterization of resistance genes through comparative genomics and genome editing.
Researchers at Kaunas University of Technology (KTU) have developed new generation polymers made from renewable raw materials, with unique properties such as self-healing, shape memory, and antimicrobial effects. These sustainable solutions can be applied in various fields including medicine, electronics, and optics.
The journal, led by Professor SUN Jiaguang, has enhanced its academic impact through dedicated development, attracting international submissions from over 130 countries. Tsinghua Science and Technology will uphold its commitment to highlighting cutting-edge research and emerging trends in information science.
This lecture examines how Philippine Sinophone poet Grace Hsieh-Hsing developed a unique poetics that transforms the archipelago into a metaphor for artistic creation and cultural identity. Her work celebrates multiplicity, fluidity, and cross-cultural pollination.
A new study finds that tropical cyclone clusters are becoming less frequent in the Northwestern Pacific and more common in the North Atlantic. The shift is attributed to climate change, highlighting the need for strengthened coastal infrastructure and emergency response systems.
Scientists create nanoscale magnetic thin films with embedded functionality by controlling atomic spacing on flexible substrates. This breakthrough opens doors to novel materials and applications in electronics, healthcare, and energy efficiency.
A new study by Bournemouth University confirms that red squirrel populations across Europe are resilient to the effects of climate change, but highlights the need for conservation efforts to protect their habitat. The study found that temperature changes and low rainfall do not directly affect the survivability of red squirrels.
A new study has developed advanced, non-destructive models to measure the aboveground biomass and volume of Populus euphratica, a keystone tree in desert riparian forests. These models reduce errors by nearly half compared to traditional equations, providing new tools for forest conservation and carbon storage assessment.
Researchers capture unprecedented 130-year evolution of Planetary Nebula IC418, revealing significant changes in emission lines and implications for stellar evolution. The study offers unique evidence of how PN central stars evolve, prompting a rethink of existing models of stellar life cycles.
A new series published in The BMJ highlights the role of the arms industry in perpetuating conflict, injuries, and death, and argues that it should be seen as a commercial determinant of health. Health professionals are urged to advocate for a reorientation away from profit-driven design and deployment towards global priorities of heal...
A groundbreaking biography of Æthelstan highlights his overlooked achievements and the significance of his reign in shaping modern England. Woodman argues that Æthelstan created England in 927AD, citing evidence from original diplomas, literary records, and archaeological sites.
A study reveals significant global disparities in cancer research funding, with lower-income countries struggling to keep pace. Cancer surgery and radiotherapy research are particularly underfunded, urging a strong case for increased investment.
A randomized controlled trial found that personalized risk messages failed to increase colorectal cancer screening participation. Despite the lack of improvement, researchers emphasize the importance of continued research and potential improvements for uptake, effectiveness, and efficiency of CRC screening.
Researchers at UCLA have developed a wearable noninvasive brain-computer interface system that utilizes AI to interpret user intent, allowing participants to complete tasks significantly faster with assistance. The system demonstrates promising results for technology to assist individuals with limited physical capabilities.
Shrews lose up to 9% of their brains during winter but remain alive and even regrow cells, unlike humans who die from similar water loss. Researchers identify key molecule aquaporin 4 involved in this phenomenon, which may offer insights into treating Alzheimer's and Parkinson's.
Researchers at the University of British Columbia have created a theoretical model for vacuum tunnelling in a 2D superfluid, where vortex pairs appear spontaneously. This work has significant implications for our understanding of quantum mechanics, phase transitions, and superfluids.
Scientists from the Smithsonian Tropical Research Institute recorded that Panama's Pacific upwelling did not occur in 2025, leading to diminished temperature drops and productivity spikes. The researchers attribute this event to a significant reduction in wind patterns, highlighting the vulnerability of tropical upwelling systems.
Researchers developed an AI model that makes individualized treatment recommendations for atrial fibrillation patients, potentially revolutionizing stroke and bleeding prevention. The model reclassified up to half of AF patients from receiving anticoagulants under current guidelines.
Researchers at Northwestern University have developed a new CRISPR delivery system that triples efficiency using DNA-wrapped nanoparticles, improving safety and effectiveness. The new system, called LNP-SNAs, targets specific cells and tissues, reducing toxicity and boosting gene-editing efficiency by threefold.
A secondary analysis of the AZALEA-TIMI 71 trial found abelacimab consistently reduces bleeding risk compared to rivaroxaban regardless of kidney function. Larger studies are needed to characterize abelacimab's efficacy in stroke prevention for atrial fibrillation patients with chronic kidney disease.
Researchers found that individuals with more severe depressive symptoms had difficulty learning to actively avoid aversive sounds, but their ability improved once they mastered the task. The study suggests that depressive symptoms may specifically interfere with learning to avoid unpleasant events rather than avoidance in general.
A recent study from Radboud University Medical Center shows that AI can rapidly assess coronary arteries for vulnerable spots, allowing for more accurate prediction of recurrent heart attacks. This breakthrough could lead to tailored medication or preventive stents, improving patient outcomes.
A study has identified KPC-type carbapenemase-producing bacteria in Chilean wastewater, raising concerns about environmental circulation of microorganisms with high antibiotic resistance levels. The finding emphasizes the need for surveillance within the framework of
Research uncovers how glutamate regulates pediatric brain tumor growth, suggesting novel approaches to treating these cancers. Inhibiting glutamate receptors has been shown to reduce human pediatric brain tumor growth in mice.
A study by Northwestern University found that Black adults are hospitalized for heart failure at age 60.1, while white adults are hospitalized at age 73.6. The gap is largely attributed to differences in insurance, unemployment, and education levels.
The merged institution offers over 320 highly competitive degrees and certificates, with academic programs ranked among the top 3% worldwide. UT San Antonio's Health Science Center is a global leader in biomedical discovery and innovation.
Routine H pylori screening after acute myocardial infarction does not significantly reduce the risk of upper gastrointestinal bleeding. The study found no notable benefit in screening for this condition, contradicting previous expectations.
The European Space Agency-led Solar Orbiter mission has split energetic particles into two groups, tracing them back to distinct solar outbursts. Researchers found that one type of particle is connected to intense solar flares and the other to larger coronal mass ejections.
Researchers analyzed blood samples from 56 ME/CFS patients and 52 healthy controls, revealing disruptions in metabolic processes and immune dysregulation. The study suggests specific intracellular pathways correlate with symptoms, leading to potential biomarkers for targeted interventions.
A new telescope shape, a one-by-20 meter rectangle, could separate stars from exoplanets and find half of all existing Earth-like planets within 30 light-years in less than three years. This design requires minimal technological development compared to other leading ideas.
A new GaN-based e-beam technology has been developed through joint research between Photo electron Soul and Nagoya University, enabling non-contact electrical inspection and metrology during semiconductor manufacturing. The technology is expected to improve yield and defect detection, leading to increased efficiency in the industry.