A new special issue of Calcified Tissue International & Musculoskeletal Research sheds light on sarcopenia's pathogenesis, clinical implications, and therapeutic targets. Researchers have made significant progress in evaluating, managing, and developing interventions for this condition.
A new study has found that most patients with osteoporosis want to receive information on their fracture risk, but only half of them actually get it. Patients prefer visual representations, such as graphs with a colored traffic-light system, to communicate fracture risk and are more likely to take medication if presented in this way.
A new review describes the development and impact of a Latin American mentorship program for Fracture Liaison Services (FLS), resulting in 64 FLSs getting started and providing coverage for over 17,200 patients. The program also supports the establishment of active communities of mentors across Mexico, Brazil, Colombia, and Argentina.
The Capture the Fracture Partnership has successfully driven global Fracture Liaison Services implementation, effectiveness, and sustainability. The partnership's unique approach, including policy, coalitions, mentorship, and scalable solutions, has delivered impactful resources and activities to prioritize secondary fracture prevention.
A new position paper reviews TBS for fracture risk prediction, treatment initiation and monitoring in osteoporosis. The evidence-based guide provides practical guidance for clinicians to integrate TBS into clinical practice.
A comprehensive review of biochemical markers for bone fragility in diabetes identifies low bone turnover and alterations in bone quality as key factors. The study suggests that glycemic control, AGEs, and serum IGF-1 may have predictive value for fracture risk in patients with diabetes.
A new special issue of Calcified Tissue International & Musculoskeletal Research explores how the skeleton functions as both a secretory organ and an endocrine target tissue. Researchers discuss key avenues in this area of research, including deciphering hormone messages encoded in bone cell secretory products.
A global study predicts a significant increase in hip fractures worldwide by 2050, with the number projected to nearly double compared to 2018. The study highlights a post-fracture treatment gap in fracture prevention, particularly for men, leading to increased mortality and dependency.
A new study has defined analytical performance specifications for 24,25-dihydroxyvitamin D examinations, which is essential for developing accurate methods to detect this metabolite. The findings show that the variation of 24,25(OH)2D concentration over time was significantly associated with 25(OH)D concentrations and body mass index.
The new FRAXplus beta version offers a more user-friendly platform to refine risk factor information, allowing clinicians to explore the impact on individual patients. The tool provides helpful features such as saved data and export options to facilitate sharing.
Professor Nicholas Harvey received the prestigious IOF Olof Johnell Science Award for his outstanding scientific contributions to osteoporosis. The award recognizes his work on fracture risk assessment tools and musculoskeletal research.
Dr Germain Honvo, a young investigator, receives the prestigious award for his international contributions to osteoarthritis research and publications on guideline development. He is recognized as a future thought leader in the musculoskeletal field.
Professor Osvaldo Daniel Messina was awarded the 2023 IOF CNS Medal for his significant contributions to osteoporosis prevention. He has expanded IOF's messages and outreach in Argentina and internationally, promoting fracture prevention and healthy mobility.
Professor Bess Dawson-Hughes has been recognized with the 2023 IOF President’s Award for her significant contributions to advancing osteoporosis research and treatment. Her extensive body of work has led to a greater understanding of nutrition's role in age-related bone loss.
The IOF Medal of Achievement is awarded to individuals who significantly advance osteoporosis research and increase awareness of the disease. Professor Jean-Yves Reginster has made major impacts on the field through his original scientific contributions, education, and advocacy.
Bernard Cortet receives ESCEO-IOF Herbert Fleisch Medal for groundbreaking contributions to osteoporosis research, including publications on clinical recommendations and patient outcomes. He is recognized for his leadership roles in French Society of Rheumatology and Osteoporosis Research and Information Group.
The International Osteoporosis Foundation (IOF) has awarded five young investigators grants for their research on nutritional factors and musculoskeletal health. The winners' projects focus on various aspects of diet, exercise, and bone health, with potential to lead to clinical advances or preventative strategies.
Renowned astronaut Samantha Cristoforetti received the International Osteoporosis Foundation President’s Award for her collaboration on the "Lift Off For Bone Health" public awareness campaign. The campaign reached over three million people, with videos viewed close to two million times.
The IOF-ESCEO World Congress on Osteoporosis, Osteoarthritis, and Musculoskeletal Diseases is the largest international scientific event devoted to musculoskeletal disorders. The congress presents new clinical advances and research on osteoporosis, osteoarthritis, sarcopenia, frailty, and rare skeletal disorders.
The Build Better Bones platform provides practical guidance on strengthening bones through targeted exercises and bone-healthy nutrition. The platform also offers helpful information for caregivers, including support with daily tasks and medical specialty knowledge.
A new economic model estimates the health benefits and budget impact of Fracture Liaison Services, showing significant reductions in fragility fractures, hospital bed days, and social care costs. The model suggests that FLS implementation would lead to improved patient outcomes and cost-effectiveness.
Biomarkers of bone turnover are essential for diagnosing and treating metabolic musculoskeletal diseases. The International Osteoporosis Foundation, IFCC, and ESCEO have collaborated to publish authoritative reviews on the use and interpretation of these biomarkers.
The IOF and ESCEO position paper recommends retaining the current WHO diagnostic criteria for osteoporosis, which has served the field well. The paper suggests that distinguishing between diagnostic and intervention thresholds can help improve treatment of patients at high risk of fractures.
The International Osteoporosis Foundation proposes a screening strategy to identify women at high risk of hip fracture, which could lead to a reduction in treatment gaps and improved identification of fractures. The approach combines low-cost assessment with targeted intervention using low-cost generic treatments.
The UK National Osteoporosis Guideline Group has published a new guideline for the prevention and treatment of osteoporosis, which includes updated recommendations for vertebral fracture detection and anabolic treatment options. The guidance aims to improve service provision in both primary and secondary care settings.
A new series of expert reviews explores less common causes of bone loss, including pregnancy-associated osteoporosis and anorexia nervosa-related osteoporosis. The reviews provide comprehensive information on these unusual conditions and their impact on bone health.
Teréza Hough, CEO of the National Osteoporosis Foundation South Africa, has been awarded the IOF CNS Medal for her outstanding contributions to bone health advocacy. Her work in raising awareness and advancing education among the public and healthcare professionals in South Africa is recognized globally.
Dr Nicholas Fuggle, a UK researcher, has been awarded the prestigious ESCEO-IOF Pierre Meunier Young Scientist Award for his significant contributions to research in musculoskeletal ageing. He is recognized for his work on determinants of musculoskeletal ageing and digital healthcare.
The Virtual WCO-IOF-ESCEO 2022 Congress will feature leading experts on osteoporosis, osteoarthritis, and musculoskeletal diseases, with a focus on new clinical research and advances in prevention and patient care. Prestigious awards will also be presented.
Professor Elaine Dennison has been awarded the IOF Olof Johnell Science Award for her significant work in musculoskeletal aging, osteoporosis, and metabolic bone diseases. She is recognized as an internationally renowned clinician, researcher, and educator.
The International Osteoporosis Foundation awarded five young researchers for their groundbreaking work on the role of nutrition in musculoskeletal health. The winners, from Australia, India, and Switzerland, were recognized for their studies on vitamin K1 intake, calcium sources, and dietary inflammatory index.
Professor René Rizzoli has been recognized for his significant and longstanding contribution to the advancement of osteoporosis research through his work on bone metabolism and mineralization. He is a respected researcher, clinician, and leader in the field of osteoporosis, with a strong focus on prevention and treatment.
The International Osteoporosis Foundation awarded Professor Thierry Thomas the IOF Committee of Scientific Advisors (CSA) Medal of Achievement for his outstanding scientific contributions to osteoporosis. The award recognizes his work on secondary fracture prevention and post-fracture care coordination programs.
Professor Antonio Cherubini has made significant contributions to the field of geriatric medicine and musculoskeletal diseases. He is recognized for his work on aging, bone health, and age-related diseases.
The IOF Skeletal Rare Diseases Academy has awarded grants to six young researchers for their outstanding work on rare skeletal disorders. The awards recognize the importance of advancing knowledge and diagnosis for these conditions.
The World Congress on Osteoporosis, Osteoarthritis & Musculoskeletal Diseases (WCO-IOF-ESCEO) 2022 will discuss secondary fracture prevention. Global experts will provide clinical guidance and information on post-fracture care through various sessions.
A new review by the International Osteoporosis Foundation highlights the importance of comprehensive post-fracture care, including exercise, nutrition, physiotherapy, and patient education. The study concludes that individualized exercise approaches can improve recovery and reduce future fracture risk.
A new European report reveals a massive treatment gap and disparities in osteoporosis care, with significant economic burden and projected increases in fragility fractures. The report emphasizes the need for improved service provision and uptake, particularly in countries with high disease burdens.
Recent clinical and experimental data suggest that vascular calcification and bone loss share common pathophysiological mechanisms. The International Osteoporosis Foundation's new review elucidates the key associations between the two disorders.
The HIPGEN study, a multinational trial, investigates the efficacy and safety of allogeneic placenta-expanded adherent stromal cells to improve recovery after hip fracture arthroplasty. The trial aims to combat immobility and associated problems by strengthening periarticular hip musculature.
Chronic kidney disease patients are at high risk of fragility fractures, yet most receive no osteoporosis therapy. A new review provides concise recommendations for clinicians to manage osteoporosis in these patients, outlining diagnosis, risk assessment, and intervention thresholds.
A new international guidance on HR-pQCT provides an overview of current clinical applications and future directions in adults. The technology holds promise for fracture risk prediction, monitoring anti-osteoporosis therapy response, and assessing metabolic bone disorders.
The journal honors the authors of its 10 most oft-cited 2019 papers with certificates of publishing excellence. The papers cover various topics in bone and musculoskeletal research, including muscle function, osteoporosis, and Paget's disease.
A new report by the International Osteoporosis Foundation reveals that fragility fractures result in 4.3 million cases and €56.9 billion in healthcare costs each year in Europe. The report also highlights significant service provision gaps, with only half of women at high fracture risk receiving therapy for osteoporosis.
Professor Cyrus Cooper has been recognized with the European Calcified Tissue Society's (ECTS) Steven Boonen Clinical Research Award for his significant progress and contribution to bone clinical bone disease research. The award honors his work on osteoporosis, metabolic bone disease, and fracture prevention.
The International Osteoporosis Foundation has published a new Executive Summary outlining key guidance for managing osteoporosis in hematologic stem cell transplant recipients. The summary provides expert recommendations for monitoring, evaluation, and treatment of bone loss in HSCT patients, including a helpful management algorithm.
A new special issue of Calcified Tissue International brings together state-of-the-art reviews on key issues in CKD-MBD. The reviews cover topics such as pathogenesis, epidemiology, challenges in management, including after kidney transplantation, and the role of bone biopsy in management.
The IFCC-IOF Committee for Bone Metabolism found significant within- and between-assay variation for ß-CTX measurement, calling for harmonization and the use of EDTA plasma for precise results. The study's recommendations aim to improve bone health globally through standardized assays.
The Covid-19 pandemic has profoundly altered global osteoporosis care, assessment and treatment. Healthcare providers reported delays in DXA scanning, interrupted medication supply, and increased reliance on telemedicine consultations.
Vertebral fractures often remain undetected despite their significance as risk factors for future fractures. Routine use of VFA in fracture liaison services helps physicians detect unrecognized fractures and inform treatment decisions. The IOF position paper emphasizes the potential of improved detection of vertebral fractures within FLS.