A new Australian study reveals hip fractures are a major public health issue with high morbidity and mortality rates. The research found that individuals with hip fractures were 3.5 times more likely to die within 12 months compared to non-injured counterparts, with excess mortality risk higher in males than females.
A French study found that direct communication with fracture patients through a dedicated case manager increased post-fracture BMD testing rates by 20%. This approach empowered patients to demand testing and care, closing the care gap in osteoporosis treatment.
The International Osteoporosis Foundation has released new position statement guidelines for managing aromatase-inhibitor related bone loss in breast cancer patients. The guidelines recommend regular assessment of fracture risk, calcium/vitamin D supplementation, and bone-directed therapy to prevent fractures and improve bone health.
A systematic review of 37 randomized controlled trials found that exercise had a positive impact on muscle mass and function in healthy older adults, while dietary supplementation showed less consistent benefits. The combined effect of exercise and nutrition intervention varied depending on the individual's baseline health status.
A new review identifies four main themes addressing gaps in osteoporosis care, including public awareness, reimbursement, and epidemiology. The authors stress the need for increased implementation of systematic approaches to prevent secondary fractures and improved management of patients with medicines negatively affecting bone health.
The IOF-ECTS Position Paper proposes measuring specific bone turnover markers to detect low adherence to oral bisphosphonates, a common issue in chronic diseases. This early identification enables discussion and intervention with patients, potentially improving treatment efficacy.
The current approaches to preventing hip fractures have shown limited efficacy, with only a 50% reduction in risk. A new review suggests exploring complementary approaches and surgical interventions for patients at high risk, including prophylactic nailing and bone grafting.
The expert panel concludes that calcium and vitamin D supplements are generally appropriate for those with high risk of insufficiency and in individuals receiving osteoporosis treatment. The evidence favors use of calcium and vitamin D supplements for fracture reduction, particularly in those at greatest risk of insufficiency.
Early and aggressive treatment with biologic drugs may halt progressive bone loss in patients with RA. Biologic therapies targeting specific cytokines and signaling pathways show protective effects on the skeleton.
The International Osteoporosis Foundation presented five researchers with prestigious Young Investigator Research Awards for their notable osteoporosis research. The award winners were selected from 168 abstracts and received a prize of $1000, a certificate, and the opportunity to present their work at a high-profile session.
The implementation of Fracture Liaison Services (FLS) is crucial to identify and treat high-risk patients with osteoporosis, reducing the risk of secondary fractures. Studies have shown that FLS can significantly increase treatment rates and prevent secondary osteoporotic fractures.
Research highlights diabetes as a significant factor in increased fracture risk, with a potential seven-fold higher risk than non-diabetic patients. Current risk factor calculators may not accurately predict fractures in people with diabetes, emphasizing the need for extra vigilance and targeted prevention strategies.
A new report by the International Osteoporosis Foundation identifies 10 major care gaps that are preventing early assessment and treatment of osteoporosis. The report highlights the need for better case finding, communication, and public awareness to tackle the global healthcare crisis arising from fragility fractures.
A recent expert review from the International Osteoporosis Foundation confirms that both type 1 and type 2 diabetes increase the risk of bone fragility. The mechanisms behind this include hyperglycemia, oxidative stress, and microvascular complications, which alter bone turnover and material properties.
A long-term study found that extra physical education classes improved girls' bone mass, structure, and strength. Girls who received 200 minutes of physical education per week showed significant gains in cortical thickness and volumetric bone mineral density compared to controls.
The systematic review concludes that fixed or age-dependent thresholds are more effective in identifying individuals at high risk of fracture than the use of bone mineral density (BMD) values alone. However, intervention thresholds must be country-specific, according to the report.
A new study by University of Toronto researchers found that increased Gαq/11 signaling inhibits the anabolic response to PTH and exercise in mice. This suggests that suppressing Gαq/11 signaling could be a promising target for treating bone loss.
A new review published by the IFCC-IOF Working Group for Standardisation of Bone Marker Assays supports the potential for bone turnover markers to provide clinically useful information. The study highlights the importance of standardization and harmonization of units for reporting serum/plasma CTX and PINP concentrations.
A study found that a twice daily program of assisted range-of-motion exercises significantly improves bone strength in very low birth weight pre-term infants. This could lead to a reduced risk of osteopenia and future fractures.
A consensus report from the International Osteoporosis Foundation Fracture Working Group recommends that patients with recent fractures should start osteoporosis medications as soon as possible. The panel agreed that anabolic agents like teriparatide may have a beneficial effect on fracture healing, while bisphosphonates may delay it.
A large study validates TBS as a standalone predictor of fracture risk, independent of FRAX, with robust results across diverse populations. The combination of TBS and clinical risk factors shows enhanced risk gradients for hip and non-hip fractures.
Professor Serge Ferrari has been recognized with the International Osteoporosis Foundation's 2016 Olof Johnell Science Award for his significant work in bone health, genetics of osteoporosis, and bone remodeling. He is a leading thought leader in the field, known for translating new research findings into improved patient care.
A new study found that the risk of a second major osteoporotic fracture increases by 4% for each year of age and is 41% higher in women than men. The risk of subsequent fractures decreases over time, but remains elevated throughout follow-up.
The IOF-ESCEO 2016 Pierre Meunier Young Scientist Awards were presented to Professors Elaine Dennison and Olivier Bruyère for their exceptional research on musculoskeletal ageing, osteoporosis, and osteoarthritis. The awards recognize their potential to become key opinion leaders in the field.
Dr. Elias Hanna Saba, Chief Executive Director of the Palestinian Osteoporosis Prevention Society, was awarded the International Osteoporosis Foundation's Committee of National Societies Medal for his over 26 years of experience in bone and muscle health and patient education. The medal recognizes his dedication to expanding IOF's mess...
Professor Eugene McCloskey was recognized for his significant advancements in vertebral fracture definition, osteoporosis epidemiology, and non-invasive assessments of bone strength. He has contributed to the development of the FRAX tool and published over 250 peer-reviewed publications.
A study by UK and Swedish researchers found that male Swedish farmers have a significantly lower risk of hip fracture, possibly due to their high levels of physical activity. The researchers analyzed data from Sweden's national registry and found that farming was associated with a 39% lower risk of hip fracture.
The IOF President's Award was presented to eight leading regional osteoporosis experts and advocates for their contributions to global osteoporosis awareness and education. The recipients were recognized for their outstanding work in the field, including Dr Ambrish Mithal, Prof Patricia Clark, and Prof Jorge Cannata Andia.
A recent study reveals that sarcopenia is expected to significantly increase in Europe, affecting up to 19 million seniors. The prevalence of sarcopenia will rise from 11.1% in 2016 to 12.9% by 2045, with women accounting for a majority of cases.
Research shows that patients with total knee replacement due to primary osteoarthritis have a low risk of hip and vertebral fractures before and after surgery. However, the risk increases by 19% for vertebral fracture and 4% for hip fracture in the years following surgery.
A UK study found no link between calcium supplementation, with or without vitamin D, and hospital admissions or mortality due to cardiovascular events. The analysis of the UK Biobank dataset showed that calcium supplementation did not increase the risk of future cardiac events.
Professor René Rizzoli, a leading Swiss investigator, has been awarded the ESCEO-IOF Medal for his groundbreaking work in basic bone science. The medal recognizes his contributions to understanding bone and mineral metabolism, with over 800 publications to his name.
Professor John A. Kanis has made significant contributions to advances in the field of osteoporosis and musculoskeletal disorders. He is the author of over 1200 papers, chapters, and books on bone disease and metabolism.
Researchers have identified new molecular targets for treating musculoskeletal diseases such as sarcopenia and osteoporosis. Several promising treatment options are expected to be available in the near future.
The International Osteoporosis Foundation is urging physicians to individualize treatment decisions based on patients' fracture risk, rather than automatically interrupting or stopping bisphosphonate therapy. The benefits of continued therapy in high-risk patients greatly exceed the risk of rare side effects.
Experts presented research on the complex relationship between diabetes and bone, highlighting increased risk of fragility fractures in people with type 2 diabetes. The studies found that diabetic patients may experience higher BMD but lower bone microstructure quality, leading to an increased risk of wrist fracture.
Research studies presented at the IOF regional meeting found significantly low levels of vitamin D in different population groups across the Middle East. The studies revealed high prevalence of vitamin D deficiency, affecting all age groups, sexes and local/non-local populations.
The IOF Young Investigator Research Award is offered to researchers aged 40 years or younger. The award includes a grant of 1000 USD and the opportunity to present at a special oral session during the Meeting.
A study found that greater neighborhood access to fast-food outlets is associated with poorer bone development in early childhood, while increased exposure to healthy specialty stores is linked to higher bone mass. The research suggests that improving the food environment could optimize childhood bone development.
A new review emphasizes the significance of nutrition throughout life for maintaining a healthy skeleton, particularly in children and seniors who are at risk of osteoporosis. The study finds that adequate intake of calcium, vitamin D, and protein can help prevent premature bone loss and fractures.
A study projects that over 319 million people will be at high risk of fracture by 2040, doubling the current number. This increase is expected in all regions, but particularly marked in Africa and Latin America, with Asia bearing the highest proportion of the global burden.
The Hungarian Osteoporosis Prevention Society has been recognized for its exceptional efforts in promoting osteoporosis awareness and prevention, as well as supporting patients through various initiatives. The award acknowledges the society's commitment to reducing falls and osteoporotic fractures among the Hungarian population.
A special issue of Calcified Tissue International & Musculoskeletal Research explores the relationship between bone material properties and skeletal fragility. The collection of reviews provides a comprehensive overview of the latest findings on mineral, collagen, and water compartments in bone.
A new review by the International Osteoporosis Foundation confirms the success of the Capture the Fracture Best Practice Framework as a single set of quality standards for Fracture Liaison Services globally. The framework helps raise standards, reinforces international guidelines, and identifies common challenges faced by FLS worldwide.
A comprehensive classification of rare genetic metabolic bone disorders has been developed, categorizing them into four major groups based on their metabolic pathway. This taxonomy provides valuable information for diagnosis, genetic testing, and the development of orphan drugs.
Osteoporosis-related fractures in China are expected to double by 2035, with costs rising to approximately US$25.58 billion by 2050. The study also found that women account for 73% of total costs, sustaining three times more fractures than men.
A new study reveals UK hospital costs for hip fractures to be approximately £1.1 billion annually, highlighting the need for preventive measures. Fracture liaison services have been shown to reduce secondary fractures and improve quality of life.
A Canadian study found a significant treatment gap among high-risk patients with prior hip fractures or osteoporosis. The study suggests that those with prior hip fractures are least likely to receive osteoporosis therapy, emphasizing the need for better guidelines and knowledge transfer strategies.
A recent study published in Osteoporosis International found that painful knee osteoarthritis in women is associated with a higher risk of early death compared to unaffected women. The study, which followed middle-aged women for 24 years, also found no link between hand osteoarthritis and excess mortality risk.
A Swedish study shows that implementing Fracture Liaison Services can prevent a significant number of fractures, saving lives and reducing healthcare costs. The model predicts a reduction in fractures by 50% among patients identified with bone mineral testing, resulting in 19 quality-adjusted life years saved.