A new blood-based test has been developed to diagnose autism in young males as early as one to two years old, outperforming existing behavioral and genetic screens. The test uses genomic biomarkers that differentiate ASD toddlers from typically developing children with high accuracy.
Researchers at Penn University developed a new model of sediment transport in rivers, showing that even calm rivers creep forward slowly due to particle interactions. The study improves geologists' ability to predict erosion rates and landscape evolution over time.
Scientists have made a breakthrough in treating patients with sickle cell disease by engineering custom blood cells that can evade the immune system. Lab-grown stem cells were reprogrammed and edited using CRISPR to replace the defective gene, resulting in healthy red blood cells that function just as well as those from unaffected donors.
The Research Data Alliance, CODATA, and WDS form a partnership to improve research data sharing and reuse. The alliance aims to provide safe stewardship and ready access to data through open and ethical sharing practices.
Researchers developed a method to measure electron interactions in high-temperature copper oxide superconductors, finding that these interactions are mediated by the spin of electrons. This breakthrough allows for better understanding of the mechanism enabling superconductivity.
A research group including a UF expert has located and narrowed down genes that play a role in Type 1 diabetes. The findings will help predict who might develop the disease and how to prevent it, leading to more effective treatments.
New research has found significant differences in the body structure of early human ancestors, including facial features and skeletal traits. The discovery of a 1.9 million-year-old pelvis and femur fossil reveals greater diversity in the human family tree than previously thought.
A long-term study on house sparrows found that offspring of older parents produced fewer young. This transgenerational age effect was confirmed by researchers for the first time in free-living animals.
New research analyzed the gut bacteria of queen bees, finding a starkly different microbiome compared to worker bees. The study suggests that modern beekeeping practices may not harm colonies by disrupting the gut microfauna.
Researchers at Scripps Research and Mayo Clinic have identified a new class of senolytic drugs that can slow the aging process. These compounds, dasatinib and quercetin, selectively induce death in senescent cells, leading to improved cardiovascular function, exercise endurance, and extended healthspan.
Individuals with boredom or frustration are more likely to develop skin-picking and other body-focused repetitive behaviors. The study found that these behaviors can satisfy an urge and deliver a form of reward, but also cause significant distress.
Researchers at the University of Pittsburgh have made a groundbreaking discovery in the study of nanomaterials, revealing that tiny tungsten crystals can exhibit deformation twinning, which affects their strength and function. This phenomenon has significant implications for the development of nanostructured metals and alloys.
A study published in Annals of Internal Medicine found that the appropriate use criteria for diagnostic cardiac catheterization may not be reliable for guiding clinical decisions. The researchers evaluated a cohort of 48,336 patients without a history of coronary artery disease and found that obstructive CAD is more likely to be diagno...
Excessive pregnancy weight gain was associated with greater overall and abdominal body fat in children and obesity at age seven. The study found that excessive pre-pregnancy weight gain was linked to a 300% increased risk of childhood obesity.
The Grete Lundbeck European Brain Research Foundation has awarded TUM Prof. Arthur Konnerth the million-euro Brain Prize for his work on two-photon microscopy, enabling detailed images of individual nerve cells and synapses in living brains. His research has improved understanding of brain development, plasticity, and functional circui...
Researchers found that restricting maternal immune cells from the placenta can protect against pregnancy complications during maternal infection and complications not triggered by prenatal infection. Blocking CXCR3 effectively eliminated fetal resorption and restored healthy live offspring to Listeria infected mice.
Researchers at UC Santa Cruz found that methane-rich groundwater contributes to lake emissions, which can exacerbate global warming. The study suggests that future warming in the Arctic could expand the active layer and increase methane transport to lakes.
Researchers at Joint BioEnergy Institute used proteomics to analyze switchgrass, a promising fuel crop candidate, and identified 1,750 unique proteins. This study demonstrates the potential of proteomics in optimizing biofuel production from switchgrass.
A new study by researchers from the Richard L. Roudebush VA Medical Center, the Regenstrief Institute, and Indiana University School of Medicine reports that a stepped-care strategy improved function and decreased pain severity in veterans with chronic musculoskeletal pain, producing at least a 30 percent improvement in pain-related di...
A UCSB ecologist examines how human disturbance affects landscape and wildlife, revealing links between conservation and human health. She finds that land-use change increases plague transmission by moving rodents closer to human habitats, while environmental conditions affect flea infestations.
A Kansas State University chemical engineer has developed a patented process to build better semiconductors, minimizing defects that can degrade device efficiency. The research uses off-axis silicon carbide substrates, which have been shown to have fewer defects than standard substrates.
A novel, fully untethered soft robot capable of repeated jumping has been developed, covering half a meter in a single hop-and-roll motion. The innovative design utilizes a combustion-powered system based on a roly-poly toy, enabling the robot to function over rough terrain.
A study by University of Leicester researchers found that millions of modern Asian men are descended from 11 powerful dynastic leaders who lived up to 4,000 years ago. The genetic link was discovered in the Y chromosomes of over 5,000 Asian men belonging to 127 populations.
A survey of 1200 Canadians found that most valued news of incidental findings, but personal utility depended on the type of findings. Individuals preferred hearing about diseases with lifestyle modifications or treatment available, while those without treatment options saw less value in receiving such information.
Researchers at MIT demonstrate that quantum sensors can outperform classical systems even when entanglement breaks down due to environmental influences. The study shows that correlations between entangled beams remain strong enough to improve signal-to-noise ratio, leading to increased sensitivity.
Researchers at Mayo Clinic and collaborators have identified a new class of senolytic drugs that clearly reduce health problems in mice by targeting senescent cells. These treatments aim to limit the effects of aging and extend patient healthspan.
Researchers discovered that Snai1 protein controls the fate of intestinal stem cells in mice, regulating their survival and differentiation. By reducing Snai1 activity, intestinal stem cells shifted towards secretory roles, impairing regeneration and promoting tumor growth.
Researchers have found that narcolepsy bears the hallmarks of a classic autoimmune disorder, with a particular autoantibody process triggering the loss of orexin neurons. This discovery opens up new avenues for diagnosis and treatment, potentially leading to a better understanding of the disease.
Research shows that eviction from housing can result in multiple negative consequences, including depression, poorer health, and higher levels of stress. Evicted mothers are more likely to experience depression, poor child health, and material hardship, highlighting the need for eviction-prevention initiatives.
Research found that socially engaged middle-aged adults with good mental health are more likely to view their lives as stories of personal redemption. This narrative format is associated with healthy psychosocial adaptation in the midlife years and resonates particularly deeply with African American adults.
A recent study examines reasons people refuse vaccines and highlights the importance of vaccination in preventing measles outbreaks. The study found that vaccine refusal can lead to unnecessary risk to children, with cases reporting complications such as pneumonia and encephalitis.
New research from University College London suggests that people with differing competence give each other's views equal weight, preventing optimal group decisions. This 'equality bias' affects decision-making processes in various contexts, including everyday situations and high-level policy decisions.
Researchers analyzed changes in climate over several decades, finding that the Earth is now entering a period of faster-than-natural warming. The study suggests that decision-makers need to better prepare for the impacts of climate change by understanding how quickly temperatures will rise.
A new study has cast doubt on the theory that ancient tsetse-infested bush stopped African herders in their tracks. The research found extensive grasslands east of Lake Victoria during a nearly 2,000-year-old settlement.
Researchers at Caltech have developed a nickel oxide film that enables record-efficient and stable chemical processes in the production of fuels like hydrogen. The film works well with a membrane to separate oxygen and hydrogen gases, ensuring safety and efficiency in the system.
Researchers at CWRU found that African-American cancer patients with depression often experience different symptoms than white patients, including irritability and social isolation. These findings suggest that culturally sensitive depression measures are needed to accurately diagnose and treat black cancer patients.
A new study has identified two distinct subtypes of childhood leukemia and found that about 13 percent of ALL cases may be successfully treated with targeted drugs. The research developed a simple lab test to determine which patients fall into the less-common subtype, opening up new hope for treatment options.
Researchers found that neurons in our brains react to time-sensitive information by favoring alternating patterns over repeating ones. This biases can impact medical decision-making and machine learning, highlighting the need for smarter programming and interfaces.
A new study found that nearly 86% of Tourette syndrome patients will receive a second psychiatric diagnosis, with 58% receiving two or more. Mood and anxiety disorders are common among TS patients, emerging as early as age 5, and are related to OCD and ADHD diagnoses.
Researchers have discovered how light disrupts biological clocks and propose a two-day recovery time for jet lag. They found that weakening synchronization among neurons governed by circadian patterns enables rapid adaptation to new time zones.
A new study reveals that mucosal-associated invariant T (MAIT) cells are dramatically reduced in individuals with type 2 diabetes and severe obesity, yet abundant in adipose tissue. MAIT cell abnormalities may contribute to obesity-associated metabolic alterations after weight loss restored circulating MAIT cells.
Researchers analyzed data from over 450 men trying to conceive, finding that heavy work-related activity, high blood pressure, and multiple medications may lower sperm counts. The study suggests environmental factors and health status play a significant role in semen quality.
A Review article discusses how existing drugs like Viagra can reduce the activity of a specific chaperone protein, HSPA5/Dna K, which may lead to anti-tumor and anti-Alzheimer's disease effects. The study also reveals potential applications in treating antibiotic-resistant infections and chemotherapy-resistant cancers.
The study introduces a new developed CSELF technique and experimental examples, which can observe not only crustal resistivity but also electromagnetic fields. The technique is found effective for data analysis, e.g., EM spectra and apparent resistivities, using software such as the 'wavelet maxima' method.
Researchers predict a shortage of over 33,000 primary care physicians by 2035 due to demographic changes and insurance expansion. To eliminate this deficit, experts suggest increasing residency production by nearly 2,200 positions by 2020.
Chemists at Scripps Research Institute have developed a broadly useful technique for building new drug molecules and other chemical products by expanding the meta-C-H activation method. The new method enables the attachment of functional groups at the meta position, previously difficult to achieve.
A new compound based on rare earth ions has been developed to measure oxygen concentrations in living tissue with high precision. The compound works by emitting coloured light that varies in colour with the amount of oxygen present, making it possible to measure oxygen using optical microscopes already present in hospitals.
A Dartmouth-led team has identified the GIGANTEA gene as a key factor in enhancing crop plant resilience to harsh conditions. This breakthrough could lead to the development of hardier crops with improved yield, addressing global food security challenges.
Researchers found that combining radiation with ipilimumab shrank tumors in some patients. The team also identified the PD-L1 pathway as a mechanism of resistance, suggesting an ideal third treatment to improve response and immunity.
Researchers have developed a new light therapy that can reach deep tumors using nanoparticles and FDG, producing different kinds of free radicals that overwhelm tumor cells. This treatment shows promise in reducing cancer growth and increasing survival rates with minimal toxic side effects.
Researchers found PET/MR to be superior in diagnosing foot pain causes, providing more diagnostic information and higher certainty than PET/CT. This non-invasive method offers an important tool for sensitive diagnosis of foot pathologies.
A new study found that rural US youth have a nearly double suicide rate compared to urban areas, with a significant increase in hanging as a method. The researchers suggest improving access to mental health care in rural areas through telemedicine and school-based interventions.
A new study published in the Review of Financial Studies suggests that regulating CEO payments and performance bonuses can lead to more profitable companies in the long term. The research found that relying on bonuses can encourage CEOs to pursue short-term gains, leading to poor strategic decisions.
A new brain imaging study has identified a specific brain area, the dorsal posterior insula, directly related to pain intensity. This discovery could help detect pain in people with limited communication abilities.
Researchers at the University of Bonn found that traffic light labels are more effective in helping consumers resist high-calorie foods than traditional nutrition labels. The study participants were willing to pay significantly more for healthy products with green labels and less for unhealthy products with red labels.
Four scientists, Winfried Denk and Arthur Konnerth (Germany), and Karel Svoboda and David Tank (USA), have been awarded the €1m Brain Prize for their invention of two-photon microscopy. This technology enables researchers to study individual nerve cells with high precision, revealing key mechanisms in brain function.
Recent research suggests that irisin, believed to travel from muscle to fat tissue after exercise, may not exist in humans. New tests used in previous studies found antibodies were poorly vetted and nonspecific, leading to false positive results.
Researchers have identified a naturally occurring protein in the brain that can act to suppress binge alcohol drinking. The study found that Neuropeptide Y (NPY) increases inhibition on cells producing corticotropin-releasing factor (CRF), leading to reduced binge drinking.
Researchers have determined the basic structural organization of the dynein-dynactin complex, a molecular motor responsible for cellular activities such as cell division and intracellular transport. The findings shed light on diseases like Alzheimer's, Parkinson's, and ALS, and could lead to new treatments.
The study recommends seeding mixtures with a higher proportion of perennial ryegrass (PRG) to speed initial establishment, while maintaining a balance between PRG and Kentucky bluegrass (KBG). The recommended ratios vary depending on the region's climate and weed pressure, suggesting a more tailored approach for Midwest lawns.