Researchers have identified a gene that may help reactivate insulin-producing beta cells in diabetics. The team, led by Professor Tessem and including four students with Type 1 diabetes, has made significant breakthroughs in understanding the molecular pathways involved.
Scientists have developed a novel PET tracer that can pinpoint thrombi throughout the body with over 97% accuracy. The tracer, Cu-64 FBP8, targets fibrin in blood clots and reflects thrombus age, enabling clinicians to choose more effective treatments.
The formation of the ASEAN Economic Community will likely lead to more deforestation, large-scale commercial monoculture crops, and environmental degradation if nations fail to address gaps in policies and enforcement. The region's agricultural land covers 1.26 million hectares, with forests covering 50% of ASEAN's total area.
Researchers found that genomic mutations in the TP53, APC, and CDKN2A genes were present in 75% of progressors with Barrett's esophagus. This ability to detect mutations in non-neoplastic mucosa can improve early detection and surveillance for patients at heightened risk for esophageal cancer.
Researchers at NYU Langone Health have successfully halted and reversed the growth of certain cancerous white blood cells in T-cell acute lymphoblastic leukemia (T-ALL) by blocking a specific protein receptor called CXCR4.
A study published in Nature Medicine found that enhancing a specific immune response can kill infection-causing fungi, such as Candida albicans, which causes life-threatening bloodstream infections. The researchers discovered that stimulating the transcription factor HIF-1α with L-mimosine led to increased production of natural antibio...
A new study from Australian and Singaporean scientists has discovered that each subtype of dendritic cell has its own unique parent cell. This discovery could lead to more efficient treatments for autoimmune diseases like lupus and rheumatoid arthritis by targeting the progenitor cells that produce these immune cells.
Massey researchers have identified three patterns of lymphocyte recovery following stem cell transplantation that are significantly associated with clinical outcomes. The study found Group B patients experienced the best clinical outcomes, while Groups A and C had poorer survival rates. The discovery builds on previous research into th...
Tropical Storm Blanca weakened before making landfall in Baja California, Mexico, with maximum sustained winds decreasing to near 40 mph. The storm's eye had disappeared by June 7, and it was expected to degenerate into a remnant low by Tuesday.
A five-year phase II clinical trial testing the ability of BCG to clinically improve type 1 diabetes in adults will be conducted at Massachusetts General Hospital. The trial aims to create a lasting therapeutic response and has received $19 million out of $25 million needed for the study.
A new study by engineers at the University of Sheffield has proven conclusively that contaminants can enter pipes through leaks and be transported through the pipe network. Groundwater with harmful contaminants can be sucked in and remain in the pipe, potentially reaching consumers' taps at low concentrations.
A fully renewable energy system featuring high shares of wind and solar energy is economically feasible for Finland by 2050, producing over 166 TWh of electricity annually. The system also includes power-to-gas technology and energy storage solutions, with total annual costs estimated at around 25 billion euros.
A study of 7,000 participants from 75 countries found that most people want access to genes linked to serious conditions and want to be 'forewarned' about their future health risk. Participants also expressed interest in having raw genomic data, despite its limited usefulness for predicting health outcomes.
Townsend's contributions to nuclear medicine have been transformative, introducing 3D PET imaging and the combined PET/CT scanner. His work has improved the signal-to-noise of reconstructed images without increasing detector material cost.
Phelps was recognized for his contributions to nuclear medicine and molecular imaging, including the invention of PET scanners. His work has improved outcomes for patients with cancer, neurological disorders, and cardiovascular disease.
Researchers at Arizona State University identify five foundations of multicellularity that cancer cells bypass to fulfill their selfish needs, leading to disastrous outcomes for the organism. The study provides clues about how to diagnose and treat cancer, a disease with rapid evolution capabilities.
Current mobile contracts are causing significant environmental damage through frequent upgrades and waste. Researchers propose a cloud-based product service system to reduce precious resources needed for mobile devices.
Diabetes research has made significant progress over the past 50 years, transforming treatment options and patient lives. The development of human insulin, improved glucose testing methods, and advanced delivery systems have greatly enhanced management of the condition.
According to a study by the University of the Basque Country, cognitive decline starts at age 20 but may not be noticeable. Episodic memory deteriorates with age, while semantic and procedural memories remain relatively stable or even improve in some cases.
A recent study published in the Journal of Personality and Social Psychology found that anticipating a potential ethical dilemma can lead to improved ethical behavior. Participants who identified similar past incidents and anticipated temptation were more likely to behave honestly than those who didn't.
Researchers at St. Michael's Hospital tested a new drug that prevents blood vessels from leaking into the lungs, reducing mortality rates in mice infected with influenza. The treatment, Vasculotide, was effective against multiple strains of flu and worked when administered days after infection began.
A new national study in the Netherlands reveals that non-invasive prenatal testing (NIPT) is accurate and preferred by pregnant women at high risk of having a baby with Down's syndrome. The TRIDENT study found 89 cases of trisomy 21, 11 of trisomy 18, and ten of trisomy 13, with only nine false positives.
The American Diabetes Association, American Association of Diabetes Educators, and the Academy of Nutrition and Dietetics have released a joint position statement outlining when and how to deliver diabetes self-management education and support (DSME/S) to patients. The guidelines highlight four critical life junctures: diagnosis, annua...
At least 6.5% of de novo genetic mutations now known to arise during post-zygotic development, affecting clinical outcomes and recurrence risk. Better information on mutation origin will enable more informed reproductive choices.
Research reveals that nearly a third of low-risk pregnancies experience unexpected complications requiring non-routine obstetric or neonatal care. The study analyzed data from over 10 million birth certificates and found that women without prenatal risk factors may still face unexpected complications during delivery or postpartum.
A new genetic mutation in the TGFB3 gene has been discovered, linking it to serious aortic disorders. This finding allows for improved diagnostic screening, enabling early identification of patients at risk and potentially preventing aortic aneurysm formation through preventive treatment.
A new study found that coral reefs in Palau's naturally acidic waters are thriving, despite the expected negative impacts of ocean acidification. However, increased bioerosion was observed, threatening the long-term survival of these ecosystems. The research team hopes to better understand how corals adapt to low pH conditions.
A national survey found that most Americans disclose their personal data for discounts because they believe marketers will harvest the data anyway. The study's lead author argues that marketers misrepresent consumers' behaviors as rational acceptance of 'tradeoffs,' which is not true.
Researchers have discovered a rabbit virus that can deliver a one-two punch, killing some kinds of cancer cells while eliminating a common complication of bone marrow transplants. The myxoma virus can quell graft-versus-host disease and destroy cancer cells, offering new hope for patients with blood cancers.
A Swiss Federal Laboratories for Materials Science and Technology (EMPA) project developed an innovative hybrid-electric powertrain for road sweepers, reducing energy consumption by 45% compared to diesel-powered vehicles. The new system also decreases CO2 emissions by 60%, thanks to natural gas's lower carbon content.
Research finds that powerful individuals respond faster to unfair treatment when they're the victims, but slower to notice when others are victimized. This disparity suggests that the powerful are more empathetic towards their own experiences and less so towards others.
A new study suggests that having a stroke can reduce brain function by 8 years, affecting memory and thinking speed equally in black and white patients. The research analyzed data from over 4,900 seniors and found that strokes have serious consequences for cognitive health.
A new study led by Dr. Jinbo Bi at the University of Connecticut School of Engineering aims to find the genetic causes of specific symptoms of substance addiction. The study will use a database of over 11,000 subjects and develop new statistical tools to classify substance dependence more effectively.
A new study found that infants who can resettle themselves after waking up are more likely to sleep for prolonged periods at night. By three months of age, most infants develop this ability, which is associated with longer sleep durations and reduced crying at night.
Rockefeller University scientists have uncovered crucial steps in the nuclear pore complex's dilation and constriction mechanism. Transport factor karyopherin initiates ring dilation by stabilizing Nup58, allowing larger molecules to pass through.
The study highlights seven potential benefits of pairing territorial use rights in fisheries (TURFs) and marine reserves, including increased fish abundance, reduced IUU fishing, and improved conservation. TURFs grant exclusive access to designated areas, promoting local ownership and conservation measures.
Researchers found that autologous bone marrow stem cells significantly reduced cranial pressure and therapeutic intensity in TBI patients, decreasing neurointensive care time by nearly 60%.
Abelardo Colon and Jennifer Gill from the University of Puerto Rico won the top honors with their video explaining a new method for disinfecting drinking water using a nanodiamond powder. The process has promising results, reducing fecal E. coli colonies and increasing density.
Researchers from the UCL Institute of Child Health and Great Ormond Street Hospital found non-invasive prenatal testing to be highly effective and acceptable to parents. Over 2,500 women underwent NIPT for high and medium risk pregnancies with Down's syndrome, showing a sharp decrease in invasive tests and increased detection rates.
Researchers at NHGRI create high-throughput gene editing system in zebrafish, allowing for simultaneous targeting and mutation of multiple genes. This method accelerates discovery of gene function and identification of disease genes in humans.
Researchers have created a nanothermometer capable of measuring temperature fluctuations in cells, achieving unprecedented precision. By combining thermodynamic tools with quantum metrology, they established the smallest possible fluctuation in temperature that can be measured.
Researchers at Hiroshima University have developed a next-generation illumination device using a silicon quantum dot-based hybrid light-emitting diode. The new LED exhibit higher current and optical power densities, and features an active area 40 times larger than traditional commercial LEDs.
Archaeologists have found evidence of a prehistoric gold trade route between the south-west of the UK and Ireland dating back to the early Bronze Age. The study reveals that gold was imported from Cornwall rather than produced locally, suggesting that it was traded for other valuable goods.
A Twin study led by TGen researchers found that a person's environment is more important than their genes in determining nasal bacteria. Some common nasal bacteria may even protect against MRSA colonization, according to the study published in Science Advances.
Researchers found that Non-Invasive Prenatal Testing (NIPT) can detect maternal cancers at an early stage, before symptoms appear. The study identified three different early-stage cancers in three women and showed the potential of NIPT for non-invasive cancer screening.
Research by Thomas Werner and colleagues sheds light on pesticide resistance in Asian fruit flies and links it to cancer-causing genes, providing new insights into human health.
Scientists at ETH Zurich have developed a technique to manipulate domain walls in multiferroic materials, which could lead to new technologies in data storage and electronics. The discovery shows that domain walls can be selectively shifted or altered using electrical fields, paving the way for new applications.
Researchers developed the smallest and most accurate thermometer that can detect tiny fluctuations in microscopic regions, enabling applications in various fields. The study provides a full characterization of temperature estimators with maximum accuracy, shedding light on their margin of error.
The Suomi NPP satellite gathered infrared data on Hurricane Blanca, which was false-colored to show locations of the strongest thunderstorms. The image revealed two areas of coldest cloud top temperatures and strongest storms west-southwest and east-northeast of Blanca's circulation center.
Researchers at Uppsala University have studied the dynamics of active swarms using computer simulations and experiments on unicellular algae. They found that the collective response was only possible when the field was varying slowly, resulting in a more persistent motion.
In silico experiments show that more accurate continuous glucose monitoring (CGM) systems can detect dangerously low blood sugar and reduce the frequency of hypoglycemic episodes. The technology improves glycemic control by providing more precise measurements, enabling better decision-making for individuals with diabetes.
The Genetics Society of America has awarded the DeLill Nasser Award to ten early-career scientists, providing travel grants to attend conferences that enhance their career. The award recognizes excellence in genetics research and supports the professional development of recipients.
The University of California, Davis has awarded a total of $2 million to five interdisciplinary teams to explore high-impact discoveries in brain science. The funding will enable researchers to conduct preliminary experiments and develop compelling data to support applications for Brain Initiative awards.
A daily sugar-sweetened beverage habit may increase the risk for non-alcoholic fatty liver disease (NAFLD), researchers found in a study of over 2,600 adults. Consuming more than one sugar-sweetened beverage per day was associated with a higher prevalence of NAFLD.
Triceratops teeth have five layers of tissue, each with a unique function, allowing them to slice through dense material and vary their diet. The discovery reveals complex dental structures among dinosaurs, inspiring new engineering techniques.
Researchers found that personality traits, particularly Neuroticism, affect brain activity in response to eye contact. Participants who scored low on Neuroticism exhibited approach-associated brain activity when looking at someone making eye contact, while those with high scores showed avoidance-associated patterns.
Research found that ladybird color reveals toxicity to predators, with more conspicuous species being less likely to be attacked. The study used modified cameras and artificial versions of each species to test predation risk, revealing that brighter colors act as warning signals.
Research from Purdue University found that adding eggs to a salad with raw vegetables significantly improves the absorption of carotenoids. This is due to the lipid content in whole eggs, which enhances the absorption of these fat-soluble nutrients.
A new study found that DNA breakage is a natural process that allows the brain to learn and generate memories, but weakens with age. Researchers discovered that DNA damage can lead to increased expression of genes involved in learning and memory, which could be detrimental as we age.
Researchers have identified a validated tool to measure symptoms and impact in eosinophilic esophagitis (EoE), a severe food allergy. The Pediatric Eosinophilic Esophagitis Symptom Score (PEESS) v2.0 questionnaire corresponded with clinical and biologic features of EoE, suggesting that eosinophil activity and mast cells contribute to d...