The company's 3D Predict assay has been validated for predicting responses to temozolomide in glioblastoma patients, with predictive accuracy comparable to its previous results in ovarian cancer. The test identifies future responders and non-responders, enabling personalized treatment strategies.
Researchers from the University of Cambridge identified Yersinia Pestis in individual burials, showing that plague victims received individual care despite the outbreak. This contradicts previous assumptions of mass burials and improves our understanding of past pandemics.
Researchers developed a prototype device that measures placental oxygen levels using near-infrared light, potentially diagnosing common pregnancy complications. The study found that women with anterior placenta and complications had lower placental oxygen levels compared to healthy pregnancies.
Researchers have discovered two distinct groups of trans-Neptunian objects with different surface colors exhibit vastly different orbital patterns. This new information can be compared to models of the solar system to provide fresh insights into its early chemistry and the formation of the Kuiper Belt.
Researchers at Moffitt Cancer Center have developed a non-invasive method to measure PD-L1 biomarker levels in lung cancer patients using PET/CT scan images. This approach uses deep learning to predict checkpoint inhibitor outcomes, which could help determine optimal treatment strategies for patients.
Neutrophils use an internal start-stop system to balance search and destroy phases for efficient pathogen elimination. This system helps prevent excessive inflammation and tissue damage. The study provides new insights into neutrophil biology, essential for immune host defense against bacteria.
A rare parasitic infection is spreading rapidly in Alberta, with over 17 human cases diagnosed between 2013 and 2020. The disease, known as alveolar echinococcosis, causes serious health complications and can be deadly if left untreated.
Experts say current approaches to relocating climate-displaced people are woefully inadequate, leading to worsening societal inequities. A new approach is needed, integrating diverse perspectives, knowledge sources, and strategies to ensure successful relocation and community thriving.
A new nematode species, Cryptaphelenchus abietis, has been discovered inside bark beetles emerging from a dead log in Nagano, Japan. The species is cultivable and may become a useful model for studying the physiological and ecological evolution of nematodes.
A large retrospective study found that convalescent plasma from recovered COVID-19 patients can improve the likelihood of survival among blood cancer patients hospitalized with the virus. The therapy, which involves transfusing plasma rich in antibodies, was associated with a lower death rate compared to those who did not receive it.
Researchers developed a fluorescent probe that binds to activated platelets, enabling clinicians to proactively treat patients before clotting or scarring occurs. The tool uses intravascular catheter-based imaging and has the potential to optimize patient outcomes.
A team of researchers has successfully analyzed over 8,000 proteins in fixed lung cancer tissue samples, providing a detailed understanding of molecular processes in cancer cells. The study aims to help identify the best treatment for each tumor and may lead to new biomarkers and therapeutic targets.
A study published in Nature Communications reveals the unique defect properties of low-dimensional materials particularly Sb2S3, which shows advantages in less dangling bonds and reduced recombination of carriers. Sulphur-rich Sb2S3 films exhibited excellent performance with lower density of defects and improved photovoltaic performance.
A survey study found COVID-19 associated with significant economic security reductions among women at high risk of HIV infection in rural Kenya. Altered sexual behavior may have temporarily decreased their HIV risk.
Researchers from the University of Copenhagen have developed a new technique to store qubits of light at room temperature, a major breakthrough in quantum research. This innovation enables the storage of qubits for milliseconds instead of microseconds, saving power and resources.
A study found that mandatory employee symptom data collection can estimate COVID-19 hospitalizations. Researchers collected daily employee symptom data from a Boston hospital and compared it to actual hospital admissions, revealing a significant correlation between the two.
A Henry Ford Health System study reveals that e-scooter-related head and neck injuries account for nearly 28% of reported riding mishaps. The study's findings highlight the importance of wearing helmets and following safety tips to reduce the risk of injury while using e-scooters.
Research reveals that parrots rely on eavesdropping on vocal interactions to assess unfamiliar individuals. In flock encounters, flocks primarily choose to follow a leader's contact call, indicating the importance of vocal imitation in social interactions.
Dr. Malene Hansen receives the Irving S. Wright Award for her work on cellular recycling and aging, while Dr. Morgan Levine wins the Vincent Cristofalo Rising Star Award for her biomarkers of aging research. Both awards recognize their contributions to advancing healthy aging through biomedical research.
Researchers developed a new computational approach, CancerCellNet, to evaluate research models. The tool uses RNA sequences to compare lab-grown cancer cells with human tumor data, finding that cell lines are genetically inferior to genetically engineered mice and tumoroids in 4 out of 5 tested tumor types.
Researchers from Nara Institute of Science and Technology discovered that an anchoring complex, Msd1-Wdr8, stabilizes microtubule creation sites in plant cells. It then recruits katanin, a key enzyme, to sever new microtubules, enabling cell division and development.
Physicists used attosecond pulses to study tungsten crystals' photoelectron emission dynamics. The results show that electrons from neighboring energy states in the valence band differ by tens of attoseconds in their response times.
A study published in Geophysical Research Letters found that anthropogenic forcing has increased drought risk in Southeast Asia, with more frequent and widespread droughts over the past six decades. The region's biodiversity is also threatened due to water scarcity issues exacerbated by climate change.
Researchers engineered NK cells to resist immune suppression and eliminated glioblastoma stem cells using inhibitors targeting TGF-β receptors. The study suggests a combinatorial approach of NK cell-based immunotherapy with disruption of the TGF-β signaling axis for treating glioblastoma.
A group of women scientists propose changes to the current system, emphasizing equal, diverse, and inclusive mentoring relationships to promote wellbeing and belonging among underrepresented groups. They also advocate for a multidimensional mentorship model that prioritizes mentee wellbeing.
The study found that Black patients hospitalized with COVID-19 face higher mortality rates due to inadequate care at predominantly minority hospitals. The disparity is attributed to systemic issues and unequal access to quality healthcare.
Researchers generated first-of-its-kind data on lightly reinforced concrete walls, which helped revise New Zealand Concrete Structures Standard and U.S. Building Code Requirements. The dataset, published on NHERI DesignSafe cyberinfrastructure, revealed hidden damage in walls that led to improved understanding of earthquake engineering.
A new study by Washington University School of Medicine identifies a protein called Interleukin-22 that may protect babies from necrotizing enterocolitis, a leading cause of death among premature infants. The findings suggest that low levels of IL-22 in the intestine lead to an exaggerated inflammatory response and tissue damage.
Environmental injustices, such as toxic landfills and chemical plants, are often located in predominantly Black, Latinx, and Indigenous neighborhoods, threatening the health of these populations. The Hastings Center Report highlights the need for bioethics to consider environmental injustice in its principles of justice.
Research reveals sacred groves in Kurdistan, Iran, harbor higher taxonomic diversity than neighboring lands, hosting rare plants and threatened animals. Local perceptions prioritize spiritual values, cultural heritage, and biodiversity protection.
University of Rochester researchers produce highly chirped pulses with relatively low-quality equipment, increasing possibilities for high-capacity telecommunication systems and astrophysical calibrations. The new method uses normal dispersion cavities, which are more common and can generate stable pulses despite high energy loss.
Scientists have identified a trigger for human embryo 'head-to-tail' axis development between days 7 and 14 of gestation. The hypoblast cells send a message to the embryo that initiates body axis formation, leading to changes in gene expression.
The Hackensack Meridian Center for Discovery and Innovation has developed the EV-CATCHER methodology, identifying and capturing tiny pieces of genetic material. This technology shows promise in diagnosing and treating diseases such as cancer early on.
Researchers at Texas Biomedical Research Institute are receiving NIH funding to investigate the precise mechanisms of Ebola virus infection, including its ability to hijack immune cells called macrophages. The study aims to understand how the virus spreads in the body and potentially develops targeted treatments.
A new study found that SARS-CoV-2 can infect the testes of infected hamsters, a finding with implications for men's health. The virus was detected in the testes of all infected hamsters during the first week but tapered off over time.
A new paper proposes reconceptualizing the future using managed retreat, which involves moving people, buildings, and assets from areas vulnerable to hazards. This approach can create a wider range of futures by combining options in different ways.
Researchers discover bacteria that can break down toxic chemicals like lindane and HBCD, which have been banned in many countries due to their persistence in the environment. The microbes produce enzymes that can degrade these pollutants, offering a potential solution for cleaning up chemical waste from landfills.
Researchers found that high serum levels of human IL-11 in mice with paracetamol toxicity led to liver cell death. However, blocking IL-11 signalling protected against liver damage and promoted survival. The study suggests a restorative effect when using anti-IL11 therapy.
A RUDN mathematician built a COVID-19 spread model to predict the disease's behavior and forecast subsequent waves. The model accurately predicted the epidemic course in countries without mass vaccination until the vaccination effect began.
A new study found that religious participation increases social trust among both millennials and older adults, with those attending church more likely to donate to charity. The research also shows that younger generations can benefit from intergenerational interactions with their elders, who tend to have more social capital.
Scientists from Rensselaer Polytechnic Institute have successfully created a novel optoelectronic phenomenon in MoS2 by breaking its inversion symmetry using strain gradients. This breakthrough demonstrates the potential for remote thermal sensing and opens up new possibilities for designing high-efficiency optoelectronics.
Researchers from Heidelberg University combined historical images and maps with current data to track glacier changes in the Nanga Parbat Massif. The study shows that the glaciers have been shrinking since the 1930s, but at a slower rate than other Himalayan regions due to avalanche activity and debris cover.
A 10-week lifestyle modification programme improved cardiovascular and mental health in people living with obesity, with significant reductions in anxiety, depression, body weight, blood pressure, and cholesterol levels. The programme's personalized approach, non-judgemental environment, and focus on emotional eating triggers led to su...
Researchers developed unitized regenerative fuel cells with improved hydrophilic and hydrophobic properties, increasing hydrogen generation efficiency by 2-fold and power generation efficiency by 4-fold. The devices can efficiently transport water and gas, improving performance and round-trip efficiency.
Researchers from the University of Jena have developed a hybrid membrane that prevents lithium dendrites and doubles the battery's lifetime. The membrane uses tiny pores to reduce ion transport, preventing dendrite nucleation.
A new study from the University of Pennsylvania School of Medicine found that Black patients die at higher rates than white patients due to unequal hospital quality. The research suggests that if Black patients had access to the same hospitals as white patients, their mortality rate would decrease by a single percentage point.
A single gene mutation can slow down cell division, preventing proper brain development and leading to microcephaly. This process involves the dysregulation of microtubules, which are essential for distributing genetic material between new cells.
A new study found that 1 in 6 privately insured families spent more than $5,000 on maternal and newborn hospitalizations, with some exceeding $10,000 if neonatal intensive care was required. Researchers analyzed data from 12 million enrollees and identified significant cost-sharing driven by deductibles and co-insurance.
Scientists at IBEC successfully controlled neuronal activity in the human brain using a light-responsive molecule named PAI. This breakthrough study demonstrates spatiotemporal control of brain state transitions, opening up new avenues for basic neuroscience research and potential brain therapies.
A study published in Cell revealed that activated Bifidobacterium infantis EVC001 programs immune cells to control inflammation and autoimmune disease risk. Breastfed infants fed this strain experienced reduced systemic inflammation and improved immune system development.
Researchers have built a comprehensive catalogue of human non-coding RNAs using three sequencing methods. The project uncovered thousands of novel non-coding RNA genes and found correlations between RNA abundance and regulatory functions.
A team of researchers has developed a combined imaging and machine learning technique that can measure glycolysis in single endothelial cells, revealing a new mechanism of glucose transport. This breakthrough could lead to better treatments for cancer, vascular diseases, and COVID-19.
Researchers at King Abdullah University of Science & Technology (KAUST) create a biomaterial that supports the growth of bone marrow precursor cells and forms tubular blood vessels, mimicking natural bone tissue architecture. This breakthrough enables the development of 3D disease models for tissue engineering and biomedical research.
Physicists at University of Gothenburg create modern version of classical experiment to directly visualize electron quantization. A single levitated droplet is used to demonstrate the minimum, indivisible amount of charge, making it visible with naked eye.
The Financial Networks discipline analyzes the interconnectedness of financial actors and contracts to understand challenges like financial crises and sustainable finance. Researchers suggest models can inform policymakers and practitioners to mitigate climate-related risks and ensure a competitive economy.
A new study published in JAMA Oncology found that convalescent plasma therapy improved survival rates in COVID-19 patients with blood cancers. The analysis showed a 48% reduced risk of death for these patients, with even greater benefits for those hospitalized in intensive care or requiring mechanical ventilation.
Two University of Arkansas researchers will study how carbon-dioxide ice pits in Mars' polar caps have formed and evolved over time. They aim to better understand the seasonal and long-term cycles of these ice pits and their impact on Martian atmospheric dynamics.
Researchers at the University of Miami argue that managed retreat should be viewed as a proactive option to support communities and livelihoods in the face of climate change. The analysis reviews existing literature on the subject and suggests considering strategic and managed retreat alongside other responses like coastal armoring.
Researchers from Hiroshima University have discovered mutant genes that facilitate genetic transfer between bacteria and other organisms across different kingdoms, including fungi and protists. The study suggests that these genes work together to activate or repress the conjugation mechanism, enabling cross-kingdom transfer.
Researchers at Osaka University have created a new, highly sensitive test for the SARS-CoV-2 virus that uses artificial intelligence and nanopore technology. The test platform achieved a sensitivity of 90% and specificity of 96% for SARS-CoV-2 detection in just five minutes using clinical saliva samples.
Researchers at MIT have cooled a large, human-scale object to close to its motional ground state, enabling the study of gravity's effects on massive quantum objects. The object, comprising nearly 1 octillion atoms, was cooled to 77 nanokelvins using LIGO's precise motion-measuring capabilities.
A new study shows that personalized online coaching can help women improve their lifestyle behaviors before and after pregnancy, particularly in overweight women. The coaching program resulted in significant reductions in smoking and drinking alcohol, as well as increased odds of becoming pregnant.
Researchers developed advanced imaging methods to study the life cycle of liquid foams, revealing that micelles play a crucial role in determining foam stability. The findings could aid in developing new products and improving industrial processes.
A new study validates the Xpert Ultra molecular test as a frontline tool in routine conditions, showing improved sensitivity over its predecessor. The test detects tuberculosis cases with lower bacterial burdens and can identify asymptomatic cases in early stages of the disease.
A study by Bentley University explores how the elderly use smart speaker technology at home, revealing heterogeneous use patterns. The results show that mornings and afternoons are more active, music and news are most prevalent, and simple commands dominate interactions.
Scientists from Shibaura Institute of Technology in Japan have created single-crystalline bulk superconductors that can trap magnetic fields, achieving temperatures above liquid nitrogen's boiling point. This breakthrough enables low-cost production of high-performance materials for various engineering applications.
A study published in Cell found a connection between breast milk, beneficial gut bacteria and the development of the immune system. The researchers discovered that babies whose intestinal flora can break down Human Milk Oligosaccharides have less inflammation in the blood and gut.
A new study by University of Utah Health finds that people with lower back pain injury miss 11 more days of work in a year when only receiving non-recommended treatments compared to those treated according to guidelines. The study suggests that adherence to medical guidelines leads to faster resolution of back pain.
Researchers at Skoltech have designed a labeling system for individual cells using polymer multilayer microcapsules that can be easily reproducible and non-toxic. The system allows for the tracking of single-cell behavior and migration with extreme precision, facilitating studies on cell movement and communication in populations.
A study found that permafrost peatlands in Russia experienced a positive effect on the climate during a cool climate period, causing plant communities to dry up and release stored carbon. This led to increased emissions of carbon dioxide and nitrous oxide, warming the atmosphere further.
A new biosensor developed by Purdue University can record and image tissues and organs simultaneously during surgery, allowing for accurate localization of critical regions. The sensor's unique design and soft bio-inks enable seamless interfacing with the curvilinear surface of organs, making it suitable for various sizes and shapes.
A newly discovered alpine plant, Dionysia tapetodes, produces fibres from tiny holes in its leaves, producing a stable wool-like material. Flavone and flavone derivatives form the complex structure of the wool through hydrogen bonding, allowing it to maintain stability.
Dr. Briana Pobiner will discuss her approach to science education and outreach in communicating about human evolution. Her methods focus on listening, respect, and finding connections with public audiences.
Researchers analyzed over 300 bronze objects to map trade networks for copper in Bronze Age Scandinavia. The study found that metal supplying networks and trade routes changed several times during the Nordic Bronze Age.
Researchers integrate disciplines to chart a roadmap for strategic and managed climate retreat. Effective processes involve diverse responses, local knowledge integration, and public deliberation. Communities can define research approaches to support adaptation strategies in their homelands.
A new study suggests that cooperative strategies for providing emergency power during long-duration outages can cost up to 40 times less than individual generators. The analysis focused on two hypothetical communities in New Hampshire and found that shared generator costs were significantly lower, making collective options more accessi...
Researchers at Nagoya University have developed a simple urine test that can detect brain tumors with high accuracy, using microRNAs as biomarkers. The new device can extract more microRNAs from just a milliliter of urine than conventional methods, and shows promise for early diagnosis and treatment.
Researchers found that fluid flow vortices have high information processing capabilities before transitioning to a Karman vortex street. Virtual physical reservoir computing using numerical simulation revealed the relationship between vortices and info processing capacity.
A new genetic cause, unrelated to OI, has been identified as causing infantile fractures in a child with EDS hypermobility type. The discovery may help prevent misdiagnosis of non-accidental trauma and improve treatment options for children with this condition.
Researchers have identified neural crest stem cells as a key factor in non-genetic drug resistance mechanisms, which can help predict potential resistance routes in patients and develop personalized therapies.
A new study reveals that many patients with high-priority kidney transplants are not being placed on the transplant waiting list, despite having long expected post-transplant survival. African Americans, uninsured individuals, and those living in lower-income communities face significant barriers to expedited waitlist placement.
Researchers found that COVID-19 vaccines pre-prepared in syringes can be safely transported under minor precautions, with messenger RNA remaining stable for at least three hours. The study aims to streamline vaccination processes, particularly in rural and less developed areas.
A new international guidance on HR-pQCT provides an overview of current clinical applications and future directions in adults. The technology holds promise for fracture risk prediction, monitoring anti-osteoporosis therapy response, and assessing metabolic bone disorders.
A new species of Paraceratherium has been discovered in China, shedding light on the dispersal of giant rhinos across Asia. The study found that the giant rhino could disperse freely from the Mongolian Plateau to South Asia along the eastern coast of the Tethys Ocean and perhaps through Tibet.
Researchers found a new treatment approach that targets the body's cellular response to SARS-CoV-2, significantly reducing virus replication. The combination of two drugs reduces virus production in cells by up to 99.5%, making COVID-19 symptoms milder and recovery times faster.
A new method for collecting pure malaria parasites from infected mosquitoes could accelerate the development of new, more potent malaria vaccines. The 'mosquito smoothie' innovation enables rapid purification with fewer contaminants, increasing scalability and efficacy.
A research team from the University of Göttingen uses powerful laser irradiation to study electrical and magnetic properties on surfaces of transparent crystals. They successfully demonstrate control over high harmonic radiation, enabling the investigation of magnetisation at the surface of magnesium oxide.
Maxime Dougados and Josef Smolen are the recipients of the EULAR Meritorious Service Award, which honors their contributions to the field of rheumatology. They have published over 1000 articles and have promoted initiatives such as FOREUM and ACR/EULAR criteria for rheumatoid arthritis.
Researchers found that altered streamside woodlands in arid regions stayed greener longer into the dry season and were less responsive to changes in groundwater levels. This threatens the long-term survival of natural forest communities and ecosystem functions.
A new study suggests that ice sheet thickness and the rate of calved icebergs limit the collapse of marine-terminating glaciers. Understanding this process is crucial for forecasting potential future sea level rise.
Foresight Diagnostics is presenting its proprietary PhasED-Seq technology at ICML for improved minimal residual disease (MRD) detection rates in diffuse large B-cell lymphoma (DLBCL) patients. The technology has been shown to detect relapsing disease 200 days earlier than current methods.
A study found that exposure to natural spaces, both public and private, reduced stress, anxiety, and improved psychological well-being among Spanish and Portuguese citizens during the first COVID-19 lockdown. In Portugal, those who maintained contact with natural spaces showed lower levels of stress and mental disorders.
Extramitochondrial cytochrome C interacts with histone chaperone ANP32B to activate PP2A and facilitate DNA repair. In severe cases of DNA damage, cytochrome C triggers programmed cell death.
Researchers identify mechanisms behind formation of sub-mesoscale eddies in Straits of Florida, which play a crucial role in retaining marine organisms and nutrients. The study reveals that shear instability on the shelf contributes to the formation of these eddies, with barotropic and baroclinic instabilities driving their development.
Coelacanths have been found to live up to 84 years old and take over five years to gestate their offspring. Their slow life history makes them vulnerable to conservation threats, with the African coelacanth assessed as critically endangered.
A team of researchers from Penn State, University of Nebraska--Lincoln, and NIST proposed a six sigma framework of quality control for additive manufacturing. The method involves five steps: defining, measuring, analyzing, improving, and controlling, to eliminate defects and drive profits.
Researchers discovered that sweat bees use patterns in the canopy overhead to navigate, finding their way home even in extremely low light conditions. This unique navigation system has implications for military applications, such as navigation for drones.
Research reveals that epigenetic changes contribute to the development of type 1 diabetes, with DNA methylation and histone modifications playing a crucial role. The study suggests that epigenetic markers could be used to monitor disease progression and identify potential therapeutic targets.
A study published in Hypertension reveals that vasopressin receptor stimulation leads to the short-term secretion of uromodulin into the urine in mice. Higher levels of uromodulin are associated with lower rates of urinary tract infections and kidney stones.
A Washington State University study of twins found that stress and anxiety during the pandemic were associated with decreased sleep quality. The researchers linked self-reported mental health issues to changes in sleep patterns, showing a two-way relationship between disrupted sleep and poor mental health.
A recent study found a direct molecular link between red meat consumption and colorectal cancer development, revealing genetic mutations indicative of DNA damage. High red meat intake was associated with increased cancer-related mortality and poorer patient survival.
Researchers have successfully driven nanoparticles to orbit below light diffraction limit, achieving high orbital rotation speeds of over 1000 r/s and subdiffraction radii of 70 nm. This new mechanism enables efficient spin angular momentum conversion to orbital angular momentum.
A FDA advisory panelist outlines numerous issues with aducanumab's accelerated approval for Alzheimer's disease, including uncertainty regarding its clinical benefits and safety. The approval may lead to a substantial financial burden on American families due to the already substantial cost of the disease.
Research finds that fruit flies use two distinct types of gustatory receptor neurons to discriminate between low and high concentrations of acid, explaining why many animals are attracted to slightly acidic foods but repulsed by highly acidic ones. A key protein, Otopetrin-like, plays a crucial role in attractive sour taste response.
The UC Davis Clinical Translational Science Center has been awarded a $33 million grant renewal from the National Institutes of Health (NIH) for a five-year period. The center will continue to provide critical funding and essential services to advance outstanding research in human health, with a focus on reducing health disparities.
Seiichi Shirai's practice of calligraphy was characterized by four aspects: interest in kanji's primitive aspects, emphasis on utility, asceticism, and rapid writing. His calligraphy reflected the universal potential of objects without being misled by external form or origin.
A new study suggests that when tyrannosaurs rose to dominance, their juvenile counterparts filled the ecological niche of medium-sized carnivores. The research analyzed 60 dinosaur communities and found no decline in prey species diversity, indicating that juvenile tyrannosaurs took over the role of missing middle-sized predators.
A study by researchers at the University of Basel found that excess nitrogen deposited into soils via air pollution endangers butterfly diversity in Switzerland. The team analyzed data on plant and butterfly diversity across 383 plots and discovered a clear link between nitrogen intake and reduced vegetation diversity.
A team of researchers from the University of Freiburg has developed a new technology that enables controlled introduction of target genes into individual selected cells. They achieved this by introducing genetic information with an optical remote control, allowing only cells illuminated with red light to take up desired genes.
CSIC scientists propose a new approach to regulate the signaling cascade of tyrosine kinases, which could lead to the development of more selective tools for research, diagnosis, or treatment of diseases. The new tool is designed to block the molecules on which kinases act, rather than inhibiting the enzymes themselves.
Researchers found that users are motivated by health consciousness, socializing, and customizing their gaming experience. The study also revealed that privacy concerns deter users from frequent engagement.
Researchers have demonstrated cooling a large-scale object to nearly the motional quantum ground state, increasing sensitivity in detecting gravitational waves. The method achieved an average phonon occupation of 10.8, suppressing quantum back-action noise by 11 orders of magnitude.
A reduced dose of gadobutrol was found to be non-inferior to the standard dose of gadoterate for contrast-enhanced brain MRI in patients undergoing multiple examinations. The study demonstrated equivalent efficacy for lesion detection and delineation.
A long-term study on wild chimpanzees found that young orphaned chimps experience high levels of stress when their mothers die, but this stress subsides over time. Adult orphaned chimps are supported by other chimps, which may contribute to their recovery from maternal loss.
A new classification of metastatic testicular cancer enables more targeted treatment, improving survival rates. The study reveals significant improvements in prognosis for patients with testicular cancer, with increased 5-year survival rates across all groups.
A team of researchers has designed an intravaginal ring (IVR) that delivers two medications known to decrease HIV transmission. The IVR, which contains a segmented section that releases hydroxychloroquine (HCQ), targets the first line of defence in reducing immune cell activation and buys time for a gene therapy treatment.
Researchers develop nanodecoys made from human lung spheroid cells that bind to and neutralize SARS-CoV-2, accelerating viral clearance and reducing lung injury. The therapy could be effective against emerging variants of the virus.
A study of over 440,000 U.S. biomedical patents found that all-female inventor teams were 35% more likely to focus on women's health than all-male teams. Female researchers are also more likely to discover female-focused solutions leading to women's health patents.
Researchers discover that twisting liquid bridges breaks them more effectively than stretching, reducing contamination and speeding up the dispensing process. The 'edge fracture' mechanism is identified as the underlying cause of this phenomenon.
The Leopoldina and RNE outline options for societal, political, and business transformations to meet the climate change challenge. They emphasize the importance of a global carbon price, infrastructure expansion, and new climate-friendly technologies.
The fast-food industry's annual ad spending increased by over $400 million since 2012, with children viewing an average of two fast food TV ads per day. The advertisements disproportionately targeted Black and Hispanic youth, groups who already face greater risk for obesity.
A new USC study has found that science denial and partisan views on Twitter can indicate where the next COVID-19 outbreak could occur. The researchers used machine-learning algorithms to analyze over 27 million tweets and found that anti-science attitudes were high in states later hit with deadly COVID-19 surges.
Researchers identified a new class of POLQ inhibitors that specifically kill cancer cells with mutations in the BRCA genes while leaving healthy cells unharmed. The drugs show promise in treating cancers such as breast, ovarian, pancreatic, and prostate cancer with BRCA mutations.
Scientists confirm NGC 1052-DF2 has only a few percent of expected dark matter content. The discovery using Hubble Space Telescope observations suggests that the galaxy formed in an environment with unusual properties, leading to its isolation.
Researchers created a neighborhood-level COVID-19 inequity index to analyze disparities in New York City neighborhoods. The index showed that areas with higher inequity indices had higher subway ridership, implying lower social distancing capacity.
Jin Hu, a physicist at the University of Arkansas, received a prestigious Early Career Research Program award from the US Department of Energy to advance research into novel topological quantum materials. His five-year award will support studies on crystal growth, characterization and various measurements in high field, low temperature...
Researchers have discovered how yeast cells seamlessly incorporate unnatural base pairs into their genetic code, a breakthrough that may lead to more effective next-generation therapeutics.
Researchers found novobiocin selectively killed tumor cells with abnormal BRCA1 or BRCA2 genes. The drug is effective even in tumors resistant to PARP inhibitors, which are a prime therapy for cancers with DNA-repair glitches.
A new algorithm called MolDiscovery uses mass spectrometry data to predict the identity of unknown substances, helping scientists avoid rediscovering known compounds and save time and millions of dollars. The algorithm could accelerate the discovery of novel natural products that could lead to the development of new drugs.
Researchers found significant alterations in serum amino acid profiles in children with ADHD, including lower levels of histidine, glutamine, and proline, as well as higher levels of aspartic acid and hydroxyproline. These findings may help develop new treatment strategies for the disorder.
A research team from Los Alamos National Laboratory and Purdue University developed bio-inks for biosensors that can localize critical regions in tissues and organs during surgery. The new biosensors allow for simultaneous recording and imaging, which could be useful during heart surgery to guide surgical interventions.
A new rapid assessment framework offers a simple tool to facilitate climate-informed conservation and nature-based solutions. The '5Ws' framework helps practitioners consider the what, when, where, why, and who of climate-informed action, enabling them to adapt investments in reforestation, fire management, and habitat protection.
Researchers at Jiangnan University developed a sensing platform to detect microRNA-205, a potential biomarker for radiation-resistant nasopharyngeal carcinoma. The method shows high sensitivity and excellent selectivity, enabling detection of miR-205 with a limit of detection of 4.78 nM.
Researchers at Stanford University have invented a manufacturing technique that yields flexible, atomically thin transistors less than 100 nanometers in length. The technique, detailed in a paper published in Nature Electronics, promises bendable, shapeable, yet energy-efficient computer circuits.
Researchers estimated survival and outcomes of very preterm infants in China discharged from neonatal intensive care units compared to those receiving full treatment. Discharge against medical advice was associated with higher mortality rates among these vulnerable infants.
Researchers investigated the association between convalescent plasma treatment and mortality in hospitalized adults with hematologic cancers and COVID-19. The study found that convalescent plasma therapy was associated with improved survival rates among these patient groups.
Case Western Reserve University researchers have identified structural elements on human prions that drive their replication in the brain. This breakthrough could lead to a new strategy to stop Alzheimer's disease and other neurodegenerative disorders, as scientists explore ways to bind to these sites to block progression.
The Chan Zuckerberg Initiative (CZI) has awarded nearly $28 million in grants to support the development of next-generation electron microscopy techniques for visualizing proteins in cells. The awards will enable researchers to obtain unprecedented views of protein structure, quantity, distribution, and interactions at near-atomic reso...
Researchers at Duke-NUS Medical School have made significant breakthroughs in understanding the transport of omega-3 fatty acids across the blood-brain barrier. The study revealed the structure and function of a protein called MFSD2A, which plays a crucial role in delivering essential fatty acids to the brain.
A study tested over 150 sorghum germplasm lines for resistance to a fungus likely to hamper production. Researchers found sources of resistance to anthracnose leaf blight, including improved lines from various regions. The findings will help develop better recommendations for sorghum growers in Pennsylvania.
A long-term study by the UK Centre for Ecology & Hydrology found that natural regeneration through seed dispersal by birds, mammals, and wind can produce biodiverse and resilient woodlands. The research suggests that incorporating passive rewilding into national planting targets could result in significant cost savings.
Researchers at Lero found that commercial video games could be used as an effective and stigma-free alternative for treating depression and anxiety. The study suggests that these games can be accessed at a low cost or for free, making them a viable option for people with limited access to mental health care.
A UofSC researcher is conducting a four-year study to improve access to alcohol use disorder treatment for vulnerable populations under Medicaid. The study aims to investigate the effectiveness of these programs and provide guidance on structuring coverage and utilization management parameters.
Researchers found that reactions with hydrogen sulfide stabilize carbon compounds, leading to increased organic carbon storage in oxygen-depleted waters. This sulfur-based mechanism could influence ocean chemistry and contribute to long-term removal of carbon dioxide from the atmosphere.
Research reveals distinctive micropillars within the carapace of a flower beetle enhance its strength and toughness while optimizing its brightly colored appearance. The study's findings have potential applications in developing new, effective bio-inspired materials.
The COVID-19 pandemic has had a devastating impact on the economy, leading to a 75 million-person increase in poverty in 2020. The study predicts that economic impacts will persist due to past epidemics' effects, with energy demand and emissions dropping significantly but mostly due to reduced economic activity.
Researchers have developed an improved organic-based, solid-state lithium EV battery by altering the electrode microstructure using ethanol. The new design increases energy density to 300 Wh/kg, a significant improvement over previous batteries with a utilization rate of nearly 98%. This breakthrough aims to reduce reliance on scarce t...
Ajo-Franklin's lab is developing advanced fiber-optic sensors to monitor CO2 storage sites, allowing for the detection of small faults that could lead to leakage. The project aims to enhance safety and security at storage sites using distributed acoustic sensing technology.
Researchers have discovered a link between ADORA2B protein in red blood cells and age-related cognitive decline. The study found that mice lacking ADORA2B exhibited accelerated aging, including poor memory and hearing deficits.
A new study suggests that asymptomatic individuals play a significant role in the transmission of pertussis, with up to 70% of infected mothers displaying no symptoms. The findings challenge traditional approaches to diagnosing and treating patients, highlighting the need for a more nuanced interpretation of qPCR test results.
A team of researchers led by Zili Shen and Pieter van Dokkum used Hubble Space Telescope to measure the distance of ultra-diffuse galaxy NGC1052-DF2, confirming it lacks dark matter. The results are based on 40 orbits of the telescope and provide crucial implications for estimating the physical properties of the galaxy.
Climate warming has diminished the high-elevation flammability barrier, allowing fires to advance uphill in Western mountains. The area burning above 8,200 feet tripled in just over a decade, with rising temperatures extending fire territory to an additional 81,500 square kilometers.
The Society for Laboratory Automation and Screening (SLAS) has announced its transition to a Gold Open Access publishing model with Elsevier. This change aims to increase public access to innovative life sciences research and drive citations for both SLAS Discovery and SLAS Technology journals.
Researchers found that vaccination with an mRNA vaccine induces antibody responses that would protect humans from infection with the gamma/P.1 variant, while hamsters previously infected with earlier strains were also protected nine months later. Previous SARS-CoV-2 infection and vaccines based on earlier strains still provide protecti...
The Quaise approach uses millimeter wave technology to melt rock, creating a strong glass liner that prevents the hole from collapsing. The technology also automatically removes vaporized rock using existing compressor technology, making it economically feasible and practical for widespread adoption.
A study found that exposure to natural spaces, both public and private, had a beneficial effect on the mental health of individuals during the first COVID-19 lockdown. Those who maintained or increased contact with these spaces presented lower levels of stress, psychological distress, and psychosomatic symptoms.
The phase III trial found that adding an immune checkpoint inhibitor to anti-HER2 treatment in breast cancer does not improve pathological complete response rates. The study enrolled 454 patients with high-risk HER2-positive early breast cancer and evaluated the efficacy and safety of neoadjuvant atezolizumab versus placebo.
Researchers designed a new type of molecular motor that can rotate in picoseconds using the power of a single photon. The motor's speed is significantly faster than existing designs, with potential applications in drug delivery, nanotechnology, and controlling biological processes.
A new global fish nutrition database is being made freely available to help combat malnutrition. The database provides vital nutritional data on over 5,000 fresh and marine fish species, which can be used to identify the most nutritious fish and support the protection of local food environments and ecosystems.
A new study found that yellow fever mosquitoes have distinct genetic changes behind permethrin resistance, including mutations in VGSC and cuticle protein genes. These mutations enable the mosquitoes to survive exposure to the pesticide, posing a significant threat to disease control.
The CSEM innovation enables devices to run independently for over a year, reducing installation and maintenance costs. The system's two-tiered data processing approach drastically reduces power requirement, with most applications using only the first accelerator.
A Rutgers-led study found that C-section babies can be restored to healthy bacteria through exposure to maternal vaginal fluids. The study's results suggest a normalization of microbiome development in the first year of life and may offer disease protection against obesity, asthma, and metabolic diseases.