A new case report uses longitudinal multi-omics monitoring to detect a precancerous pancreatic tumor in a patient. The study highlights the potential of blood-based LMOM for early detection and personalized medicine, warranting further translational research.
Researchers have identified CAR-T cell therapy as a potential treatment for autoimmune diseases such as rheumatoid arthritis, SLE, and type 1 Diabetes Mellitus. Early studies have shown promising results in reducing disease activity and improving patients' quality of life, but long-term data on safety and efficacy is limited.
Researchers at U of T have mapped the movement of proteins encoded by the yeast genome throughout its cell cycle, identifying patterns of emergence and disappearance or movement to specific areas. The study provides a unique dataset that offers a genome-scale view of molecular changes during cell division.
Research suggests that female physicians have a clinically significant impact on patient outcomes, with lower mortality and readmission rates compared to male doctors. Female patients benefit more significantly from treatment by female physicians, possibly due to better communication and understanding of sensitive health issues.
Researchers have discovered how bella moths, found in eastern North America, Central America, and the Caribbean, use toxic pyrrolizidine alkaloids to guard their eggs and deter predators. The moths' ability to safely consume these toxins is linked to specific genes that may confer immunity.
The study predicts that QAHE can be achieved within a single material system composed of van der Waals coupled Bi and MnBi2Te4 monolayers by applying strain, magnetic field, or twisting the materials. This provides a practical material platform for topological electronics.
The European Union is urged to adopt a balanced, empirically sound approach to regulate substances of human origin. Properly devised rewards increase supply without compromising quality and safety. The EU's new regulation should prioritize self-sufficiency while ensuring safe and accessible supplies for all in need.
A new study by Dr. Ben Hudson from the University of Exeter Law School criticizes the European Court of Human Rights for reversing its principles on protecting asylum seekers. The research finds that the court has become uncertain about what makes an applicant 'sufficiently vulnerable' to receive special protection.
A George Mason University researcher is creating a website to tell the story of the American Indian Science and Engineering Society (AISES) at its 50-year milestone. The website will feature oral history interviews, annotated photographs, and other resources documenting AISES's growth and impact.
A new Spanish study provides the first stratification of the risk of developing dilated cardiomyopathy among symptom-free genetic carriers. Researchers found that nearly 11% of genetic carriers developed the disease within a median follow-up period of 37 months.
A University of Adelaide study found that climate change is helping tropical fish species invade temperate Australian waters. The warming current keeps baby fish warm, increasing their survival chances. As temperatures rise, these tropical fish will eventually grow to their full size and compete with native fish for resources.
Researchers identified four types of family learning environments in Scandinavian families, shaped by parental values and socioeconomic status. The study found that family activities, emotional climate, and everyday organisation play a crucial role in shaping children's learning environments. Four categories were developed: Expansive C...
Researchers have discovered a new class of inorganic liquid crystals with high electric field responsivity, enabled by 2D ferroelectric materials. This breakthrough enables ultra-low operational electric fields and practical applications for electro-optical devices.
A new clinical trial reveals that a novel writing therapy can significantly reduce cancer-related trauma, depression, anxiety, and hopelessness in late-stage cancer patients. By confronting their greatest fears through written exposure-based coping (EASE), participants experience improved mental well-being.
The study introduces pDA-nHA/PEKK composites with high strength and bioactivity, surpassing conventional melt blending techniques. The novel approach mimics the hierarchical structure of cortical bone, resulting in enhanced osteo-inductive abilities and mechanical strength.
Researchers monitored disaster risk caused by unstable coal pillars in multi-coal seam mining, finding that their failure can lead to mine earthquakes and collapse. The study provides insights for assessing stability and risk in residual coal pillar-rock formations, highlighting the need for customized application of findings.
Research reveals correlation between muscle fiber diameter and mtDNA copy number across different fish types, suggesting genetic regulation role in shaping phenotypes. Decrease in muscle mtDNA copy number during winter may contribute to growth heterosis of allotriploid fish.
Astronomers have produced the first high-resolution map of a massive explosion in a nearby galaxy, revealing a gas outflow that would take 20,000 years to travel across the galaxy. The discovery provides important clues on how space between galaxies is polluted with chemical elements.
Researchers discovered that gut bacteria can dynamically reprogram gene expression based on local conditions like inflammation or viral attacks. This adaptation strategy may worsen disease by crippling production of molecules that regulate the immune system and attenuate gut inflammation.
Researchers from Technion Faculty of Biomedical Engineering developed a breakthrough method for bio-printing live cells and tissues using external sound wave irradiation. The innovation enables precise localized delivery of biocompatible materials for various biomedical applications, reducing invasive surgeries and associated risks.
A VACCELERATE Consortium survey study found that 57% of global infectious diseases experts ranked influenza as the top pandemic risk, with Disease X and SARS-CoV-2 also among the most concerning pathogens. The study highlights the need for continued preparedness and surveillance to prevent pandemics.
Researchers have developed a method to quantify entanglement using standard entanglement witness procedure, enabling estimation of lower bounds for various entanglement measures. This approach normalizes the witness operator into a trace distance that characterizes distinguishability between entangled and separable states.
Depletion of axonal mitochondria disrupts autophagy, leading to abnormal protein build-up in neurons. Restoring mitochondrial levels restores autophagy and recovers impaired neuron function.
The conversion of CO2 into chemicals and fuels through direct hydrogenation is a recognized strategy for mitigating climate change. Copper-based catalysts have been investigated for CO2 hydrogenation, but their practical application faces challenges due to reduction and aggregation tendencies.
A new neural network-based system called BONES improves video streaming quality by up to 13% while reducing download size, according to NJIT researcher Jacob Chakareski. The system uses a mathematical function to optimize data transmission and can be applied to various platforms, including popular video conferencing services.
Researchers developed a wearable technology system to monitor surgeons' postures during long surgical procedures, finding that 52.1% of active time was spent in static postures. The study showed potential for improving ergonomics and preventing injuries by providing objective feedback on posture correction.
Astrocyte activity starts approximately 20 seconds before epileptic neuronal hyperactivity, suggesting their role in triggering seizures. Researchers found that blocking metabolic activity of astrocytes reduces the magnitude of epileptic neuronal hyperactivity.
Researchers at CeMM Research Center create 'vpCells' method for simultaneous fluorescent labelling of many proteins, enabling precise tracking and exploration of protein function. The approach opens up new applications in fundamental cell biology and drug discovery.
A study by UBC researchers found that only 40% of coho salmon remained alive three kilometers from release, and fewer than one-quarter reached the Lions Gate Bridge 20 kilometers away. The 'mortality hot-spot' was confirmed in Burrard Inlet, but the research also suggests ways to increase survival rates through changing release locations.
Research identifies tumor deposits as detrimental to CRC and GC patients' survival, emphasizing the need for thorough retrieval and aggressive adjuvant therapy. Preoperative detection methods are being developed using new imaging technologies and AI, aiming to improve early evaluation of tumors.
A study led by the University of Rhode Island found that the American woodcock, a migratory shorebird, overlaps its migration and reproductive periods. The bird was found to nest multiple times during migration, with some females nesting up to six times, allowing them to reduce energy costs.
A review of A-HCC highlights the connection between heavy drinking and the risk of this aggressive form of liver cancer. The study proposes developing better diagnostic tools and treatment options through understanding how alcohol contributes to its development.
Researchers found that weathering in the region leads to an overall CO2 uptake, but near-surface processes only determine the CO2 balance in areas with a thick and cold crust. In contrast, the western side of the Central Apennines is a significant CO2 emitter due to deep-seated outgassing from carbonate rocks.
A new study found that human-induced environmental changes around Antarctica are contributing to sea level rise in the North Atlantic. The research team analyzed two decades of oceanographic data and found a 12% weakening of the Atlantic Meridional Overturning Circulation deep water limb.
Researchers developed a fiber-like electrode material that stores more energy, has greater mechanical strength and conductivity. The material can be mass-produced using wet spinning technology, enabling flexible wearables.
Researchers found that modern weather models can accurately predict satellite movements affected by weather events like tropical cyclones with tall clouds. This understanding enhances satellite tracking and control, improving efficiency and reliability of satellite operations.
A Rutgers study reveals that price is the biggest barrier to a vibrant second-hand EV market, with lower-income buyers often priced out of the market. The study suggests that increasing charging station availability and expanding subsidies could promote greater used EV uptake across income groups.
A new study led by the University of Michigan predicts that climate change will increase the financial benefits of residential rooftop solar panels in the US, with households potentially saving hundreds of dollars annually. The study found that increased cooling demand due to warmer temperatures and rising air conditioning needs will d...
Scientists have developed a new method to efficiently extract information from galaxy surveys, enabling the use of high-order information in future studies. This breakthrough has significant implications for understanding dark energy, dark matter, and gravity.
The project aims to establish a first-of-its-kind lab for neuromorphic imaging and digital twins at George Mason University. This will support research, local organizations, and beyond, with potential applications in fields like Air Force, Space Force, Civil Engineering, Machine Learning.
Researchers at KAIST have developed a hybrid sodium-ion battery with high energy and power density, enabling rapid charging in under a few seconds. The new battery technology has the potential to revolutionize energy storage for electric vehicles and other applications.
Climate scientists predict a 7 in 10 chance of record-breaking temperatures and humidity in the tropics, threatening humanitarian aid and medical care. El Niño's impact on tropical heat and humidity is expected to compound the effects of global warming, leading to extreme humid heat stress.
Researchers identified an enzyme called WEE1 that promotes the generation of more milk-producing cells by halting cell division at just the right time. This process, known as endoreplication, generates cells with double the normal complement of DNA, leading to increased milk production.
Researchers at Gladstone Institutes have identified a blood coagulation protein, fibrin, as the culprit behind toxic inflammation and neuron loss after a major head injury. This finding can inform new treatment strategies for traumatic brain injuries, which often lead to dementia, depression, and difficulty concentrating.
A team of researchers at MIT has developed a new method to model the irrational behavior of humans, which can be used to predict their future actions. By analyzing an agent's previous decisions, the technique infers its computational constraints and adapts to human collaborators' weaknesses.
Researchers at EPFL have developed a comprehensive model of the quantum-mechanical effects behind photoluminescence in thin gold films, which could drive the development of solar fuels and batteries. The study reveals unexpected quantum effects emerging in films as thin as 40 nanometers.
A new method using computer simulations predicts the feasibility of materials suited for ion exchange, allowing for the synthesis of new compounds at relatively low temperatures. This advancement accelerates the development of new materials suitable for improved energy technologies.
The American Association for Thoracic Surgery (AATS) and Cardiovascular Research Foundation (CRF) will collaborate on the development of New York Valves 2024, focusing on advances in surgical approaches and techniques in valve disease. The summit will feature expert discussions, live-case demonstrations, and hands-on training.
A recent study published at the ESCIMD Global Congress found that Black female patients are at higher risk of death from carbapenem-resistant enterobacterales (CRE) bloodstream infections. The study analyzed data from 362 US hospital patients and discovered that Black females had a significantly increased risk of mortality compared to ...
Researchers have made groundbreaking measurements of the electron capture of the artificial isotope holmium-163, which allows them to determine a Q value for the decay process. This enabled them to measure the neutrino mass with unprecedented precision using a super-sensitive scale and detector.
Researchers at University of Texas M. D. Anderson Cancer Center have developed a new method for developing immunotherapy drugs using engineered peptides. The approach improved tumor control and prolonged survival in preclinical models of breast cancer.
In Brazil, around 90% of sugarcane area uses natural enemies like microorganisms and biochemicals for pest control. Researchers have registered over 629 biological products, with a steady increase in use year after year.
Researchers at DGIST developed a method to fixate chemisorbed oxygen molecules via h-BN encapsulation, leading to passivation of 2D semiconductor crystals. This approach can revolutionize the control of defect states in these materials.
Researchers at Aston University discovered that experienced Ordnance Survey mapmakers and novices interpret aerial images differently. The experts rely on stereoscopic cues, while novices focus on lighting cues, leading to improved performance through repeated exposure and perceptual learning.
Researchers at DGIST developed a neural network module called DG-Net, which can accurately extract objects from aerial and satellite imagery. The technology has shown exceptional accuracy in geographic spatial object segmentation, outperforming existing models.
A study by Germans Trias i Pujol Research Institute reveals that people living with HIV who contract COVID-19 face a significant increase in cardiovascular disease risk. The researchers identified several factors associated with this increased risk, including age, previous cardiovascular disease, and chronic conditions.
A study published in ACS' Journal of Agricultural and Food Chemistry found that plant-based steaks and cold cuts have varying levels of protein quality and digestibility. The nutritional value depends on the plants used to create them, with some showing comparable profiles to their meat counterparts.
Researchers discovered that liver cells secrete SAA proteins, which hinder T cell infiltration and attack tumors. Deleting SAA proteins increased survival times and likelihood of cures in mice with pancreatic tumors.
Researchers identified a unique autoantibody signature in approximately 10% of patients with MS, appearing years before symptom onset. This finding could revolutionize patient care and treatment strategies for multiple sclerosis.
A new research scheme addresses the limitations of previous anonymous authentication methods, providing both public linking and tracing capabilities while ensuring access control. The proposed scheme enables accountability without relying on a trusted authority, making it feasible for future multi-authority extensions.