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Science News Archive November 2026


New treatment approach for calcified nodules shown to improve coronary stent expansion in Mount Sinai clinical trial

Researchers at The Mount Sinai Hospital found combining rotational atherectomy and intravascular lithotripsy before coronary stent placement improves stent expansion in patients with calcified coronary nodules. The study, NODULE-SHOCK, showed a 19% increase in stent area compared to IVL alone.

SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalJournal of the American College of Cardiology·TypeRandomized controlled/clinical trial·DateNov 1, 2026

Mechanical thrombectomy linked to lower mortality in intermediate-risk pulmonary embolism

A primary meta-analysis of 4,200 patients found lower short- and long-term mortality with mechanical thrombectomy compared to anticoagulation alone. However, larger randomized trials are necessary to confirm these findings and determine patient benefit.

SourceSociety for Cardiovascular Angiography and Interventions·JournalJournal of the Society for Cardiovascular Angiography & Interventions·TypeMeta-analysis·DateNov 1, 2026