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CHICAGO, IL — Since the start of the 21st century, more than 800,000 people in the US have died from firearm-related injuries, and over two million have been injured. These harms stem from homicide, suicide, and unintentional shootings, reverberating through communities and resulting in psychological, social, and economic consequences that go far beyond physical injury.
Amid these persistent challenges, JAMA and JAMA Network convened a JAMA Summit in March 2025, bringing together 60 thought leaders from medicine, public health, law, industry, and community violence intervention, with a singular focus: how to substantially reduce firearm harms. Today, JAMA publishes the JAMA Summit Report on Reducing Firearm Violence and Harms, a blueprint for action featuring experts from across sectors committed to advancing evidence-based solutions to reduce firearm-related injury and death.
The report synthesizes a rich evidence base on policies and interventions that demonstrably reduce firearm violence and deaths, including state laws on handgun purchaser licensing and safe firearm storage, strong domestic violence restraining orders and removal policies, extreme risk protection orders, community violence intervention (CVI) programs, environmental changes (i.e., greening vacant lots and improving street lighting), and collaborative, focused policing.
Authors pinpoint five essential actions to drive progress in the coming years:
1. Invest in community-based initiatives and address upstream drivers like housing, opportunity, and mistrust.
2. Advance technologies such as biometric “smart guns,” passive detection systems, and safety tools driven by artificial intelligence (AI), while strengthening oversight for firearms as consumer products.
3. Shift public and policymaker understanding about the preventability of firearm harms, reframing gun violence as a public health, social, and environmental issue.
4. Support coordinated action at federal, state, and local levels informed by scientific insight and advocacy.
5. Expand research on the effectiveness, scaling, and equity of interventions—from basic science to agent-based modeling and community impact assessment.
The JAMA Summit Report is coauthored by 41 experts. JAMA Media Relations curated the following experts for media interviews based on their contributions to the report and their subject matter expertise.
Community Violence Intervention
Law & History
Public Policy & Political Science
Technology
Sociology
Epidemiology
Clinical Medicine (including surgical and psychological specializations)
Medical Research (including outcomes, prevention, and policy evaluation)
JAMA Summit convenes leaders across disciplines and sectors to propose innovative, actionable steps addressing urgent health challenges. Outcomes include special communications, policy recommendations, and a growing library of multimedia resources designed to catalyze broader discussion and action.
Learn more about past JAMA Summits and read resulting JAMA Summit Reports: AI in Medicine and Clinical Trials .
(doi:10.1001/jama.2025.18076)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations .
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