For people who smoke cigarettes, a hospital stay may be an opportunity to quit. New clinical guidelines developed with experts from MUSC Hollings Cancer Center call on hospitals to make tobacco treatment a routine part of care.
The guidelines from the American College of Chest Physicians, or CHEST , recommend an “opt-out” approach: Every hospitalized patient who currently smokes should be proactively offered tobacco treatment. That marks a shift from approaches that offer treatment primarily to patients who say they are ready to quit.
The goal is to keep tobacco use from getting lost among the many other health concerns being addressed during a hospitalization, said Benjamin Toll, Ph.D. , director of the MUSC Health Tobacco Treatment Program and co-director of the Lung Cancer Screening Program . Toll helped to develop the guidelines along with Alana Rojewski, Ph.D. , associate director of the Tobacco Treatment Program.
“Unfortunately, but understandably, tobacco can get overlooked,” Toll said. “Our providers are so busy clinically. There’s a lot to do.”
But a hospital stay can be an important window for intervention. Patients cannot smoke while there, meaning those who regularly smoke may experience nicotine withdrawal. That gives providers an opportunity to treat those symptoms while also opening a conversation about whether the patient might want to stop smoking for good.
“It's important just to have the conversation,” Toll emphasized.
The recommendations are based on an extensive review of the scientific literature. The panel screened more than 9,300 research abstracts and included 142 studies in its evidence base.
The strength of the evidence varied by topic. Rojewski said relatively few studies have directly compared medications or examined questions such as how much counseling patients should receive. Where research was more limited, the multidisciplinary panel drew on members’ clinical expertise and experience treating tobacco use in real-world healthcare settings.
The result is a mix of strong and conditional recommendations that follow patients across the continuum of tobacco treatment – from identifying who should be offered help to providing medication and counseling in the hospital to continued support after discharge.
At the heart of the guidelines is a simple change: A patient’s current smoking status – not whether the person says they are ready to quit – should trigger an offer of tobacco treatment.
That differs from an opt-in approach, in which treatment is offered only to patients who indicate that they are willing or motivated to quit. The distinction matters because readiness to quit is not necessarily a simple yes-or-no decision, Toll said.
“There’s obviously those that are very ready and those that are a hard no,” he said. “But there’s a fairly big middle section of maybes.”
Patients in that middle ground can easily be missed when treatment depends on someone explicitly asking for help. Rojewski pointed out that it is not uncommon for providers to offer treatment to the same person more than once before the answer changes to “yes.” Consistently offering treatment increases the chances that support will be available when a patient is ready to make a quit attempt.
“It really is about planting that seed and being there when they’re ready.”
Building treatment into routine hospital care also reduces reliance on individual clinicians to raise the subject while managing a patient’s hospitalization. Instead, the health system creates a consistent process for reaching anyone identified as currently smoking.
Once a patient is identified, the guidelines address two related goals: managing nicotine withdrawal during the hospital stay and helping patients to stop smoking after they leave.
To manage withdrawal, the panel suggests starting nicotine replacement therapy, or NRT, during hospitalization. NRT supplies nicotine without the harmful chemicals produced by burning cigarettes. Combining a long-acting nicotine patch with a short-acting option such as a nicotine gum or a lozenge can provide steady nicotine levels and reduce breakthrough cravings.
Hospitalization can also be a chance to begin medication that supports a longer-term quit attempt. The guidelines strongly recommend starting varenicline, a prescription medication that reduces nicotine cravings, before patients leave the hospital. That allows treatment to begin in a controlled setting and gives patients a plan before they return home, where cigarettes and smoking triggers may again be part of daily life.
But medication is only half the picture. Counseling is another essential part of treatment.
The guidelines strongly recommend that hospitalized patients who smoke receive at least 15 minutes of tobacco treatment counseling rather than only brief advice. Together with medication, that counseling can support patients before they leave the hospital.
The next challenge is helping patients to maintain that progress once they go home.
The guidelines call for telephone-based counseling after discharge and proactive outreach rather than simply referring patients to a state quitline. Quitlines remain an important, scalable resource, the panel noted, but the evidence showed that follow-up from the health system was more effective than a passive referral alone.
Toll hopes the recommendations encourage more hospitals to build tobacco treatment programs that can reach patients during hospitalization and continue that care after discharge.
“There are not a lot of health systems that are currently doing this,” he said. “I really hope these recommendations encourage a dedicated tobacco program inside hospitals where treatment is offered to all, and there’s also some kind of treatment offered post-discharge.”
Importantly, the guidelines do not proscribe who should provide that care. Depending on the hospital, tobacco treatment could involve nurses, doctors, social workers or other allied health professionals. Rojewski said having a tobacco treatment specialist is ideal, but the larger priority is creating a workable system that ensures patients receive treatment rather than allowing responsibility to fall through the cracks.
Ultimately, Toll and Rojewski hope the guidelines change what patients who smoke can expect from a hospital stay: Not pressure to quit but a routine offer of evidence-based help and continued support if they choose it.
“I really, really hope that this encourages more health systems to create opt-out tobacco treatment programs,” Toll said. “We want that to occur and for more patients to receive lifesaving tobacco treatment.”
Rojewski agreed.
“Hospitals are a place that can help increase the access and reach of tobacco treatment,” she said. “If treatment is built into the health system, patients who might not otherwise receive help with smoking will have another opportunity to access it.”
###
About MUSC Hollings Cancer Center
MUSC Hollings Cancer Center is South Carolina’s only National Cancer Institute-designated cancer center with the largest academic-based cancer research program in the state. With more than 230 faculty cancer scientists from 20 academic departments, it has an annual research funding portfolio of more than $50 million and sponsors more than 200 clinical trials across the state. Hollings specialists include surgeons, medical oncologists, radiation oncologists, radiologists, pathologists, psychologists and other clinical providers equipped to provide the full range of cancer care from diagnosis to survivorship. Hollings offers state-of-the-art cancer screenings, diagnostics, therapies and surgical techniques within its multidisciplinary clinics. Dedicated to preventing and reducing the cancer burden statewide, the Hollings Office of Community Outreach and Engagement works with community organizations to bring cancer education and prevention information to affected populations throughout the state. For more information, visit hollingscancercenter.musc.edu .
CHEST Journal
Commentary/editorial
People
Tobacco Treatment in the Inpatient Setting: An American College of Chest Physicians Clinical Practice Guideline
2-Sep-2026
All panelists were reviewed for their potential conflicts of interest (COI) by the CHEST Professional Standards Committee (Table 1). Nominees without any significant COI’s were approved, and those with potential intellectual and/or financial COI’s that were manageable were “approved with management.” Panelists “approved with management” did not participate in discussions and did not vote on recommendations for which they had COI’s.