Gerd Pluschke (Swiss Tropical Institute, Basel, Switzerland) and colleagues in Cameroon, Ghana, and Switzerland show that eight weeks of antibiotic treatment in patients with Buruli ulcer reverses local immunosuppression and leads to an active inflammatory response in different compartments of the skin. Buruli ulcer is a debilitating ulcerative skin disease caused by Mycobacterium ulcerans involving extensive tissue destruction and suppression of the local immune system.
Citation: Schütte D, Um-Boock A, Mensah-Quainoo E, Itin P, Schmid P, et al. (2007) Development of Highly Organized Lymphoid Structures in Buruli Ulcer Lesions after Treatment with Rifampicin and Streptomycin. PLoS Negl Trop Dis 1(1): e02. doi:10.1371/journal.pntd.0000002
MEDIA CONTACT:
Gerd Pluschke
Swiss Tropical Institute
Molecular Immunology
Socinstr. 57
Basel, CH 4002
Switzerland
Tel 41 61 2848235
gerd.pluschke@unibas.ch
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