In an accompanying commentary, Marco Colonna from Washington University discusses the paradoxical role of type 1 interferon in the immune suppression following LCMV infection and the novel way in which this virus not only eludes specific immune surveillance, but actively suppresses the immune response.
TITLE: Viral targeting of hematopoietic progenitors and inhibition of DC maturation as a dual strategy for immune subversion
AUTHOR CONTACT:
Noemi Sevilla
Universidad Autónoma de Madrid, Madrid, Spain.
Phone: 34-91-397-8477
Fax: 34-91-397-4799
E-mail: nsevilla@cbm.uam.eds
View the PDF of this article at: https://www.the-jci.org/press/20243.pdf
ACCOMPANYING COMMENTARY: Viral immunosuppression: disabling the guards
AUTHOR CONTACT:
Marco Colonna
Washington University School of Medicine, St. Louis, Missouri, USA.
Phone: 314-362-0367
Fax: 314-362-4096
E-mail: mcolonna@pathology.wustl.edu
View the PDF of this commentary at: https://www.the-jci.org/press/21166.pdf
Journal of Clinical Investigation