Despite its increasing prevalence, a painful condition called bladder pain syndrome, or interstitial cystitis, remains understudied with limited treatment options. In a new eNeuro paper, Min-Zhi Su and colleagues, from Sun Yat Sen University, used a rat model of bladder pain syndrome to explore if electroacupuncture can alleviate pain and improve bladder function. Electroacupuncture nerve stimulation therapy has shown promise in treating conditions like Huntington’s disease and Amyotrophic Lateral Sclerosis, but researchers have not explored its utility in this context. The researchers discovered that this kind of therapy can reduce neuropathic pain, promote urinary function, and decrease neuroinflammation. They also discovered a mechanism through which electroacupuncture may work. According to the authors, these findings suggest that electroacupuncture may be a promising treatment strategy for bladder pain syndrome, though future work in more advanced animal models—and eventually in people—is needed.
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About eNeuro
eNeuro is an online, open-access journal published by the Society for Neuroscience. Established in 2014, eNeuro publishes a wide variety of content, including research articles, short reports, reviews, commentaries and opinions.
About The Society for Neuroscience
The Society for Neuroscience is the world's largest organization of scientists and physicians devoted to understanding the brain and nervous system. The nonprofit organization, founded in 1969, now has nearly 35,000 members in more than 95 countries.
eNeuro
Electroacupuncture Neural Stimulation Mitigates Bladder Dysfunction and Mechanical Allodynia through Downregulation of the BDNF-TrkB Signaling Pathway
10-Mar-2025
The authors declare no actual or apparent commercial interest in the material presented in this paper.