About The Study: In this qualitative study of patient experiences with glucagon-like peptide-1 receptor agonists (GLP-1 RAs), participants described GLP-1 RA therapy functioning as a facilitator rather than a replacement for lifestyle change, emphasizing the need for behavioral interventions alongside pharmacotherapy to sustain treatment benefits. Quality of care was highly variable; thus, standardized guidelines for patient education and clinical support could improve expectation management around likely adverse effects and long-term management.
Corresponding Author: To contact the corresponding author, Isabella de Vere Hunt, MD, email Isabella.deverehunt@phc.ox.ac.uk .
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(doi:10.1001/jamanetworkopen.2026.16951)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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