A study finds that a noninvasive preimplantation genetic test of cell-free DNA in the culture media of 52 human in vitro fertilization blastocysts did not produce false negatives for aneuploidy, was less prone to errors caused by potential mosaicism in the blastocyst, and was a more reliable test than the current testing method, trophectoderm biopsy.
Article #19-07472: "Noninvasive preimplantation genetic testing for aneuploidy in spent medium may be more reliable than trophectoderm biopsy," by Lei Huang, Berhan Bogale, Yaqiong Tang, Sijia Lu, Xiaoliang Sunney Xie, and Catherine Racowsky.
MEDIA CONTACT: Xiaoliang Sunney Xie, Peking University, Beijing, CHINA; e-mail: sunneyxie@pku.edu.cn
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Proceedings of the National Academy of Sciences