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The anti-acne medicine isotretinoin, which can cause defects in a developing fetus, is now used by almost 2 in 1,000 girls and women of childbearing age, according to analysis of German database of 25 million

01.25.24 | PLOS

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The anti-acne medicine isotretinoin, which can cause defects in a developing fetus, is now used by almost 2 in 1,000 girls and women of childbearing age, according to analysis of German database of 25 million
Age-specific and age-standardized prevalence with 95% confidence intervals (shaded area) of isotretinoin use per 1,000 girls and women aged 13-49 years between 2004 and 2019 in the German Pharmacoepidemiological Research Database (GePaRD). Credit: Reinold J, et al., 2024, PLOS Medicine, CC-BY 4.0 (https://creativecommons.org/licenses/by/4.0/)

The anti-acne medicine isotretinoin, which can cause defects in a developing fetus, is now used by almost 2 in 1,000 girls and women of childbearing age, according to analysis of German database of 25 million

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In your coverage, please use this URL to provide access to the freely available paper in PLOS Medicine : http://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1004339

Article Title: Use of isotretinoin among girls and women of childbearing age and occurrence of isotretinoin-exposed pregnancies in Germany: A population-based study

Author Countries : Germany

Funding: The study was partly funded by the German Federal Institute for Drugs and Medical Devices, Bonn (BfArM, V-18281/ 68605 / 2019-2020) ( https://www.bfarm.de ). The study proposal was submitted by UH. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

PLOS Medicine

10.1371/journal.pmed.1004339

Competing Interests: see manuscript

Keywords

Data Analysis Databases Dermatology Gender Studies Medications Pharmaceuticals Pregnancy

Article Information

Journal
PLOS Medicine
DOI
10.1371/journal.pmed.1004339
COI Statement
Competing Interests: see manuscript

Contact Information

Claire Turner
PLOS
medicinepress@plos.org

How to Cite This Article

APA:
PLOS. (2024, January 25). The anti-acne medicine isotretinoin, which can cause defects in a developing fetus, is now used by almost 2 in 1,000 girls and women of childbearing age, according to analysis of German database of 25 million. Brightsurf News. https://www.brightsurf.com/news/LN2NKGM1/the-anti-acne-medicine-isotretinoin-which-can-cause-defects-in-a-developing-fetus-is-now-used-by-almost-2-in-1000-girls-and-women-of-childbearing-age-according-to-analysis-of-german-database-of-25-mil.html
MLA:
"The anti-acne medicine isotretinoin, which can cause defects in a developing fetus, is now used by almost 2 in 1,000 girls and women of childbearing age, according to analysis of German database of 25 million." Brightsurf News, Jan. 25 2024, https://www.brightsurf.com/news/LN2NKGM1/the-anti-acne-medicine-isotretinoin-which-can-cause-defects-in-a-developing-fetus-is-now-used-by-almost-2-in-1000-girls-and-women-of-childbearing-age-according-to-analysis-of-german-database-of-25-mil.html.