In an accompanying commentary, Jonathan Makielski from the University of Wisconsin writes, "These findings provide an excellent illustration of a causal relationship between the interaction of the environment and genetic background in SIDS. For families of SIDS victims, a clear delineation of risk factors, both genetic and environmental, will be instrumental in identifying children who may benefit from therapeutic intervention."
TITLE: A common cardiac sodium channel variant associated with sudden infant death in African Americans, SCN5A S1103Y
AUTHOR CONTACT:
Steve A.N. Goldstein
Pritzker School of Medicine, University of Chicago, Chicago, Illinois, USA
Phone: (773) 702-6205; Fax:(773) 702-4523; E-mail: sangoldstein@uchicago.edu
View the PDF of this article at: https://www.the-jci.org/article.php?id=25618
ACCOMPANYING COMMENTARY: TITLE: SIDS: genetic and environmental influences may cause arrhythmia in this silent killer
Jonathan C. Makielski
University of Wisconsin, Madison, Wisconsin, USA
Phone: 608-263-9648; Fax: 608-263-0405; E-mail: jcm@medicine.wisc.edu
View the PDF of this article at: https://www.the-jci.org/article.php?id=27689
Journal of Clinical Investigation