STATINS FOR THE TREATMENT OF MULTIPLE SCLEROSIS
In a Reflection & Reaction article, John Greenwood and colleagues discuss the evidence supporting a role for statins--such as lovastatin and atorvastatin--in the treatment of multiple sclerosis by the prevention of CNS leucocyte accumulation. Since the mechanism of action of statins differs from that of currently approved treatments, there may be some benefit in a combination approach.
MILD COGNITIVE IMPAIRMENT
Mild cognitive impairment is a recently adopted term to describe the transition between healthy ageing and dementia. In a review article, Charles DeCarli discusses the prevalence, pathophysiology, prognosis, and possibilities for the treatment of this condition. "Current estimates suggest that many people have various cognitive impairments that will substantially increase their risk of developing dementia, hence the urgent need to identify and treat these disorders", he writes.
OTHER REVIEWS:
The Lancet Neurology