MATRIX: A USAID Project to Advance the Research and Development of Innovative HIV Prevention Products for Women

Prototypes of a novel vaginal ring design being put to the test in a study that will inform final design of a dual-purpose ring for prevention of both HIV and unplanned pregnancy

Researchers are evaluating two prototype placebo rings in a study to determine their safety and usability for women. The goal is to inform the final design of a dual-purpose ring that can prevent both HIV and unplanned pregnancy for a month at a time.

SourceMATRIX: A USAID Project to Advance the Research and Development of Innovative HIV Prevention Products for Women·TypeRandomized controlled/clinical trial·DateMar 21, 2024

“On-demand” HIV prevention method for women being tested in second early phase trial

The TAF/EVG fast-dissolving vaginal insert is being evaluated in a Phase 1 study to determine its safety and user acceptability. The study aims to assess the product's effectiveness as an on-demand HIV prevention method for women, particularly those who do not want or can't use daily PrEP or long-acting products.

SourceMATRIX: A USAID Project to Advance the Research and Development of Innovative HIV Prevention Products for Women·TypeRandomized controlled/clinical trial·DateDec 7, 2023

Researchers launch first study of a vaginal film that dissolves in 30 days to assess its acceptability as a potential HIV prevention method for women

A vaginal film designed to dissolve in 30 days is being tested for its feasibility and acceptability as a potential HIV prevention method for women. The study will enroll 100 women and assess the comfort, usability, and safety of two prototype films with different shapes.

SourceMATRIX: A USAID Project to Advance the Research and Development of Innovative HIV Prevention Products for Women·TypeRandomized controlled/clinical trial·DateNov 2, 2023