Golden Gate method enables rapid, fully-synthetic engineering of therapeutically relevant bacteriophages
Researchers from New England Biolabs and Yale University have developed a first fully synthetic bacteriophage engineering system using the High-Complexity Golden Gate Assembly platform. This method simplifies strain engineering techniques, allowing for rapid creation of tailored therapeutic strains to overcome antibiotic resistance.
SourceNew England Biolabs·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateJan 19, 2026