A study published in PLOS ONE found that bovine tuberculosis is prevalent among wild boar, red deer, and fallow deer in Doñana National Park, threatening the health of endangered lynx and domestic cattle. The high prevalence suggests that a feeding ban alone would have limited effect on controlling the disease.
New research reveals that commercial bees are infecting and spreading diseases to wild pollinators, contributing to declining pollinator populations. The study found that commercially produced bumble bees carry a harmful pathogen that can be transmitted to wild bees at flowers.
A recent study published in PLoS Neglected Tropical Diseases found that parasitic worm infections can increase the risk of acquiring HIV/AIDS. The study showed that rhesus macaques with acute schistosomiasis were more susceptible to an HIV-like virus, with higher peak viral loads and memory cell concentrations.
A recent study found that past climate changes and sea level fluctuations may have contributed to the formation of new species in the Amazon. The research, published in PLOS ONE, used leafcutter ants as a model organism to investigate how geography and climate affect species diversity.
Research finds that international malaria financing is insufficient to achieve the goal of halving the global burden of malaria by 2015. Funding commitments are largely tied to stable P. falciparum risk, leaving countries with high but low-risk populations poorly supported.
Researchers from KEMRI-Wellcome Trust Research Programme assess rotavirus diarrhoea in young children, finding over 2% hospital admissions. Meanwhile, PLOS Medicine article discusses evidence-based TB diagnosis, citing the importance of strong evidence backing expenditure on diagnostics.
The new resource allows users to view, store, and edit biological pathway information, leveraging collective expertise to facilitate content collection and curation. WikiPathways provides a wealth of annotated information, maximizing the value of biological data and supporting future hypotheses and discoveries.
A study by David Stuckler and colleagues found that International Monetary Fund loans were associated with a 16.6% rise in death rates from tuberculosis (TB) in the former Soviet Union and Central and Eastern European countries between 1992 and 2002.
A novel computational model illustrates how HIV evades the human immune system through 'escape mutants', which can lead to AIDS progression. The study suggests a new vaccine design approach by reducing viral replicative capacity.
A team of researchers found that the 'trust' hormone oxytocin is released from dendrites in response to suckling, triggering a positive-feedback loop that coordinates intense bursts of release. This discovery sheds light on how mothers form strong bonds with their infants.
Researchers at Washington University School of Medicine have identified MDA-5 as the primary immune sensor that detects norovirus infections. The discovery may lead to the development of a treatment that prevents or reduces infection, particularly for individuals with common genetic variations that make them more susceptible.
Researchers developed computer models of RNA molecules evolving by mutation and natural selection, showing that optimal organisms often require a long sequence of interacting mutations. This challenges the idea that natural selection always leads to the best possible organisms in the long run.
A new study identifies 39 genes differentially expressed between workers with varying Gp-9 genotypes, including those regulating chemical signaling and response. The study also found 91 genes indirectly influenced by social environment, highlighting the genetic complexities of social behavior.
Researchers discovered high levels of ciprofloxacin resistance in Escherichia coli among Amerindians from Guyanese rainforest, despite no reported use of fluoroquinolone antibiotics. Chloroquine treatment for malaria may contribute to bacterial resistance.
Researchers found a negative correlation between dengue hemorrhagic fever and moderate to high mosquito density, with a 40% higher incidence in areas of moderate mosquito density. The study suggests that reducing Aedes mosquitoes may not effectively control the spread of the disease.
Researchers used a computer model to simulate interactions between monkeys and found that females are more dominant in groups with relatively more males. The study suggests that female dominance develops through self-organisation, not inborn traits.
Researchers identified certain genes that enable frogs to develop resistance to harmful bacteria and disease. The discovery may provide new strategies for protecting frog populations in the wild by selectively breeding individuals with known disease-resistance genes.
A 28,000-year-old Cro-Magnoid individual from Southern Italy exhibits anatomical and genetic characteristics similar to those of modern Europeans. The study challenges the long-held assumption that Neandertals are the ancestors of modern Europeans.
A systematic review of 13 observational studies found that diabetes mellitus increases the risk of active tuberculosis by about a factor of three, suggesting a possible role in over 10% of TB cases in India and China.
A new definition for intermediate syndrome (IMS) resulting from organophosphate poisoning has been proposed based on a study of 78 patients. The researchers found that specific changes in nerve transmission occurred before the development of IMS, suggesting that these changes may be an indicator of future poor outcome.
Reduced carbon emissions from tropical deforestation and degradation can be achieved through improved forest management techniques. Studies show that better logging practices can minimize ecological impact by up to 50% and reduce carbon losses by approximately 30%.
A study on leatherback turtle migration patterns reveals that they respond to strong ocean currents with rapid movements to maintain their southern route. The researchers identified specific high-use areas occupied by the turtles, providing crucial information for conservation efforts.
A study published in PLOS Pathogens identifies over 120 viral proteins that disrupt key cellular processes, including gene expression and antiviral responses. Herpesviruses employ multiple strategies to manipulate the host cell nucleus, particularly through disruption of PML bodies.
Common genetic variations in nicotine receptors significantly increase the chance of life-long nicotine addiction among European American youth smokers. A study of 2,827 long-term smokers found that those who began smoking before age 17 with a high-risk haplotype had a 1.6- to 5-fold increased risk of heavy nicotine dependence.
Researchers investigate how humans perceive humanoid robots and attribute mental qualities, finding increased brain activity in the medial prefrontal cortex. Participants enjoyed interactions more when robots displayed human-like features, suggesting a link between human-robot interaction and mentalizing.
Researchers found that songbirds control their songs with superfast muscles that can produce work at frequencies over 100 Hz, a 100 times faster than human blink rate. This discovery suggests these muscles are more common than previously thought and provide precise control of song modulations.
Researchers found that bold birds, who sing from exposed sites, are more likely to be explorers and risk-takers in the wild. These individuals have a higher mating success due to their attractiveness to females.
A University of Sussex-led study found that the brain responds more strongly to piano sonatas played by musicians than by computers. The researchers discovered that the brain's electric activity increases when the music is performed with emotional expression, indicating a deeper understanding of musical meaning.
A new system called HealthMap has been developed to gather, organize, and disseminate online intelligence on disease outbreaks. This can facilitate early outbreak detection, increase public awareness of disease outbreaks prior to formal recognition.
A new approach to archiving human genetic information is introduced through Gene Wiki, an online repository of human genes stored within Wikipedia. This community-annotated system allows for a flexible and organic accumulation of science, enabling all readers to edit and add to the gene wiki pages.
MDR-TB experts recommend new tools for testing, clinical trials of simplified treatments, and improved diagnosis strategies to overcome barriers. Pilot projects show promising results in low-income settings with treatment success rates of 59-83%.
Researchers from Harvard Medical School and Brandeis University used a full-genome RNAi screen to identify genes essential for brain development in neurons. The study revealed unexpected roles for genes involved in signaling, protein trafficking, and cytoskeletal proteins.
A study published in PLOS Medicine found that a public-health approach to HIV treatment in South Africa is equally effective as an individualized approach used in Switzerland. Treatment initiated early greatly reduces HIV levels and viral rebound, but higher mortality rates were observed in South Africa.
Researchers analyzed fecal samples from 25 chimpanzee communities and found a range of SFV infection rates from 44% to 100%. The study highlights the importance of understanding cross-species infections in primates and their potential impact on human health.
Researchers from Leiden University Medical Center used CT scans to compare wood densities of classical and modern violins. The results suggest that the homogeneity in wood density may explain the superior sound production of Cremonese violins.
A study published in PLOS ONE found that editors' expectations for quality reporting have a strong relationship with journal quality. Italian journals, which lack international standards, perform poorly compared to UK journals, indicating the importance of editorial leadership in promoting high-quality research.
A study published in PLOS ONE found that eating broccoli rich in glucosinolates can help men stay healthy and reduce the risk of developing prostate cancer. The research, led by Professor Richard Mithen, showed that relatively low amounts of cruciferous vegetables can have large effects on gene expression.
A study found that children tend to overestimate the relative numbers of certain taxa, such as mammals and birds, while underestimating others, including social insects and annelids. This knowledge is crucial for inspiring future conservationists.
A recent study published in PLOS ONE found that a significant proportion of Chinese consumers admit to purchasing tiger products, despite widespread support for the country's ban on selling these products. The researchers also discovered that 71% of respondents preferred products made from wild tigers over those from farmed tigers.
Researchers analyzed the genetic status of six Adi subgroups using microsatellite markers, finding low genetic differentiation among them. The study also reveals a closer relationship between the Adi tribe and neighboring Tibeto-Burman-speaking tribes in India.
A new study by the HealthEmotions Research Institute found that anxious brains consistently respond more strongly to stress and show signs of anxiety even in safe situations. Anxious monkeys showed higher brain activity in the amygdala, a part of the brain that regulates emotion, which corresponded to higher levels of stress hormones.
The DOT1B enzyme helps epigenetically regulate VSG genes, allowing parasites to switch between coat variants. In its absence, silent genes become active, slowing down the switching process.
Researchers discovered that mammalian clock proteins respond directly to light, similar to plant cryptochromes. In humans and animals, this response affects circadian rhythms differently than in mice, where missing cryptochromes lead to complete loss of rhythm behaviors.
A survey of 17 countries found that 16.2% of US adults have used cocaine in their lifetime, with 42.4% using cannabis. The study suggests that drug use is not simply related to policy and that socioeconomic factors play a significant role.
In a study published in PLOS Biology, researchers found that parietal neurons selectively track target location during visual search tasks. Adding distractors decreased parietal neuron firing rates, reducing target-related response and correlating with increased reaction times.
Researchers Francesco Checchi and Les Roberts argue that an independent body is needed to accurately document death rates during humanitarian emergencies. Such a body could provide a basis for both humanitarian advocacy and political advocacy, and could help prevent the DRC experience from being repeated.
A study published in PLOS ONE estimates that both island species were isolated around the same time, approximately 250,000 years ago. The researchers suggest that a moderate-sized ancestral population could reconcile differences in gene divergence patterns among the species.
Neglected tropical diseases in the US disproportionately affect poverty-stricken communities, particularly minorities. These chronic infections cause significant disability, impaired child development, and adverse pregnancy outcomes.
Currently used pain assessment tools may not accurately reflect the pain experience in infants. A study published in PLOS Medicine found that changes in brain activity correlated with clinical pain scores, but were more strongly linked to behavioral components such as facial expression than physiological components like heart rate. The...
A survey found that many health research reporting guidelines lack funding, leading to poor methodology and findings. The EQUATOR Network aims to harmonize development and promote use of guidelines through training and resources.