Researchers find that stress hormone THP increases anxiety in adolescents by reversing its calming effect, contributing to pubertal angst. The discovery sheds new light on the causes of mood swings during puberty.
SUNY Downstate researchers develop a substance that inhibits the progress of multiple sclerosis in an animal model. The agent, a novel calpain inhibitor, can be administered orally and has shown promise in treating both acute and chronic phases of MS.
Researchers at SUNY Downstate Medical Center have found that PNC-28, a human protein, can destroy pancreatic tumor cells in animals without harming healthy cells. The study's results are encouraging and suggest PNC-28 may be an effective agent in treating cancers, particularly when delivered directly to the tumor.
Scientists at SUNY Downstate Medical Center discovered a molecular mechanism maintaining memories in the brain by inhibiting a specific enzyme, protein kinase M zeta. This finding may have applications in treating chronic pain and memory loss conditions such as post-traumatic stress disorder.