Wellcome Trust/ Cancer Research UK Gurdon Institute

Cell-to-cell contacts control liver regeneration

Researchers found a regulatory cell type, mesenchymal cells, control liver regeneration through cell-to-cell contacts. The study suggests that the wrong number of contacts between populations can lead to cancer or chronic liver diseases.

SourceWellcome Trust/ Cancer Research UK Gurdon Institute·JournalCell Stem Cell·TypeExperimental study·DateAug 2, 2021

Cancer drug can rebalance kidney function in a devastating genetic disease

Researchers discover cancer drug improves kidney dysfunction in mouse model of Lowe syndrome and Dent disease 2, offering hope for first disease-modifying treatment. The study suggests that alpelisib could also help alleviate neurological symptoms.

SourceWellcome Trust/ Cancer Research UK Gurdon Institute·JournalKidney International·DateSep 9, 2020