Barcodes
Articles tagged with Barcodes
Pioneering new technique to barcode cells
Scientists have developed a pioneering new technique to barcode individual cells more accurately and efficiently. The method combines artificial intelligence with microfluidics, allowing for real-time analysis of single cells and enabling the efficient sorting and counting of cells.
Johns Hopkins study: Biosensor barcodes identify, detail ‘chatting’ among cancer cells
The study uses a new barcode system to track complex signaling activities in cancer cells and identify key protein interactions. The technique enables real-time analysis and synchronization of protein activity over time.
Taking the guesswork out of genetic engineering
A team of Harvard researchers created an integrated pipeline, STAMPScreen, to help genetic engineers identify target genes and perform screening studies. The protocol combines computational tools with lab experiments to quickly and efficiently test gene function in living cells.
Microscopic imaging without a microscope?
Researchers developed Seq-Scope technology to visualize all gene expression from a tissue sample, offering ultra-high-resolution imaging. The method, using high-throughput sequencing and barcode-based spatial coordinates, enables diagnosis of diseases at the microscopic scale.
Diagramming the brain with colorful connections
Scientists at Cold Spring Harbor Laboratory have created a new tool called BARseq2 that uses genetic tags to label brain cells and trace thousands of brain circuits simultaneously. This allows researchers to examine the complex interactions between neurons, enabling a better understanding of brain function and behavior.
Using CRISPR, new technique makes it easy to map genetic networks
A new CRISPR-based technique allows researchers to profile a cell's entire genome and identify the DNA sequences regulating specific genes. This enables simultaneous testing of thousands of experiments, paving the way for faster discovery of genetic networks and potential therapeutic targets.
Nanoscopic barcodes set a new science limit
The University of Technology Sydney led collaboration created a nanocrystal growth method that produces programmable atomic thin layers, arbitrary barcoded nanorods with morphology uniformity. The result is millions of different kinds of nanobarcodes for future nanoscale sensing applications.
Scientists develop AI-powered 'electronic nose' to sniff out meat freshness
A team of scientists has developed an AI-powered 'electronic nose' to assess meat freshness accurately. The device uses a barcode that changes color over time in response to gases produced by decaying meat, and a smartphone app powered by artificial intelligence.
A DNA-based molecular tagging system that could take the place of printed barcodes
A DNA-based molecular tagging system called Porcupine has been developed by University of Washington and Microsoft researchers. The system uses distinct DNA strands to encode digital tags with high accuracy and security, making it suitable for tracking high-value items and preventing tampering.
Dynamic photonic barcodes record energy transfer at the biointerface
Researchers developed bioresponsive dynamic barcodes using cavity-enhanced radiative energy transfer, converting biomolecular information into distinctive photonic barcodes. The system can detect molecules in a droplet with improved signal-to-noise ratio, enabling real-time intermolecular interaction and biosensing applications.
Why do people respond differently to the same drug?
A comprehensive study of RGS proteins reveals how they modulate cell signaling and explains why people's responses to the same drugs can vary widely. The researchers created a roadmap for how GPCR signals are routed in cells, highlighting the potential for new treatment approaches for various conditions.
How to map brain connections using DNA barcodes
Researchers developed a new method to map brain-wide connections using DNA barcodes, reducing costs compared to traditional methods. The approach generates virtually infinite labels to distinguish individual cells, enabling the creation of accurate anatomical maps.
DNA-barcoded microbial spores can trace origin of objects, agricultural products
Researchers developed a synthetic microbial system to determine the location of origin for objects, using DNA-barcoded spores that can be sprayed onto goods and detected months later. This approach helps determine the source of foodborne illnesses, which affect millions in the US annually.
Using genetically engineered, barcoded microbes to track food contamination and more
Researchers introduce a novel approach using genetically engineered microbes with DNA barcodes to track food contamination and provenance. The system, called barcoded microbial spores (BMS), can persist on surfaces for months and transfer between objects, making it suitable for tracing supply chains.
Genetic barcodes can ensure authentic DNA fingerprints
Researchers propose genetic barcodes to guarantee DNA samples' authenticity before reaching the lab, mitigating cyberbiosecurity threats. The system introduces non-harmful material into samples as they're collected, which acts as a password ensuring their genuineness upon processing.
Structual color barcode micromotors for multiplex biosensing
Researchers at Southeast University have developed a novel kind of microtort with stable structural color for multiplex assays. These micromotors can efficiently accelerate mixing speed and increase probe-target interactions, leading to faster and more sensitive detection. The unique structural color coding allows for simultaneous mult...
Natural ingredients in supplements, nutraceuticals get a new type of barcode
A team of researchers has developed a method to authenticate botanical ingredients by assigning unique chemical barcodes, which can distinguish between different parts of the same plant and detect chemical contaminants. The new barcode system uses nuclear magnetic resonance and statistical analysis to group similar samples together.
Tiny light-up barcodes identify molecules by their twinkling
Researchers have developed a technique using time signals 'temporal barcodes' that can label molecules with distinct flashing patterns. This allows for the detection and identification of any number of molecules, including proteins, at the molecular scale, increasing efficiency and reducing costs compared to traditional methods.
Seafood mislabelling persistent throughout supply chain, study finds
A recent study by University of Guelph researchers found a 32% seafood mislabelling rate, with the problem persisting throughout the supply chain. The mislabelling rate was highest at retailers, indicating the role of distribution and repackaging in the issue.
Sequencing pollen DNA to discover insect migratory routes
A new study reveals that insects can transport pollen from one continent to another, enabling the mixing of plant species across vast distances. By analyzing the DNA sequences in this pollen, researchers were able to identify 157 species of plants from Africa and Europe.
Making a map of the brain
Researchers have created a groundbreaking cellular atlas of the brain, revealing over 70 different types of neurons, their locations, and functions. This breakthrough technology allows for unprecedented insights into brain organization and behavior.
New technology can detect hundreds of proteins in a single sample
A new technology developed by McGill University scientists can detect hundreds of proteins with a single blood sample, improving the analysis of biological markers and providing key information on health. The technique uses multicolour fluorescent dyes to barcode micro-beads, enabling detection of multiple proteins in parallel.
Recording every cell's history in real-time with evolving genetic barcodes
Researchers develop a method to continuously record cells' development using genetic barcodes, allowing them to trace the full developmental lineage of every mature cell. This breakthrough resolves longstanding questions about brain patterning and promises to exponentially increase understanding of cellular growth and disease emergence.
DNA barcodes that reliably work: A game-changer for biomedical research
Researchers developed a new error-correction method for DNA barcodes, reducing errors from 10% to 0.5%, allowing for more ambitious medical research and larger-scale experiments. The FREE method enables accurate tracking of biological molecules, including cancerous tumors and drug candidates.
Robot bloodhound tracks odors on the ground
Researchers developed a robot that can rapidly detect odors from sources on the ground, including footprints. The robot uses a high-speed gas sensor to track invisible odor sources and read binary barcodes deposited on the surface.
Taking CRISPR from clipping scissors to word processor
Researchers developed MAGESTIC to refine gene-editing process, enhancing precision and increasing cell survival rates by sevenfold. The new platform enables precise editing of genetic variants, helping uncover impact on cellular function and disease susceptibility.
Natural barcodes enable better cell tracking
Researchers at Wyss Institute for Biologically Inspired Engineering at Harvard developed a new genetic analysis technique that harnesses natural barcodes in human genomes. This allows for faster, cheaper, and simpler tracking of cell identities across experiments, enabling large pools of cells from multiple people to be analyzed.
Democratizing single-cell analysis
Scientists at Allen Institute and University of Washington developed scalable SPLiT-seq method to characterize RNA in individual cells, enabling identification of various cell types in the brain. The technique significantly lowers the cost barrier for labs that want to perform single-cell profiling.
Building a DNA barcode library for the Canadian flora using herbarium collections
A new study by Dr. Maria Kuzmina provides a vast DNA barcode library for the Canadian flora, covering 98% of vascular plant species, using herbarium specimens. The scale of sampling and quality of curation lend the library taxonomic authority, offering a valuable resource for modern plant sciences.
A genus of European paper wasps revised for the first time using integrative taxonomy
Researchers analyzed over 260 wasp specimens to identify all species and determine their distribution. The study reveals three distinct species within the Polistes gallicus complex and a new species from Morocco, Polistes maroccanus.
Fly hunter has described 30 new species
A Norwegian PhD candidate has discovered 30 new species of non-biting midges, using DNA barcoding to confirm the identities of the insects. The research provides significant contributions to the knowledge of this insect group and highlights the importance of DNA barcoding in understanding biodiversity.
Using barcodes to trace cell development
Researchers at the German Cancer Research Center create a new barcode system to study blood cell development, revealing two major branches that give rise to different cell types. The technology allows for precise tracking of individual cells and has implications for cancer research and other tissue studies.
Food or fraud?
Italian scientists introduce NanoTracer, a simplified assay combining DNA barcoding with nanotechnology to authenticate food with the naked eye. The test detects substitutes and adulterants in products like European perch and saffron powder.
Fighting forgery with paper fingerprints
Researchers from Newcastle University have found an inexpensive and easy way to validate the authenticity of ANY paper document by taking a picture with a standard camera. The unique 'texture' fingerprint for every sheet of paper can be identified and verified with 100% accuracy, making it highly reliable even under rough handling.
Better barcoding: New library of DNA sequences improves plant identification
A new database of genetic information, developed by researchers at Emory University, has improved the accuracy of plant identification using DNA sequencing technologies. The new library uses the rbcL gene, a popular barcode in plants, to identify species from tiny amounts of material, enabling faster and more accurate analysis.
Detection system reads biomolecules in barcoded microgels
Researchers developed a cost-effective system to detect biomolecules in real-time using spectrally encoded microgels, enabling accurate measurements of microRNAs in blood samples. The system achieved a detection limit of 202 femtoMolars and demonstrated specificity for multiplex measurement conditions.
Major urinary proteins do not allow kin recognition in male mice
Researchers from Vetmeduni Vienna analyzed MUP genes and proteins in wild house mice, finding no variation among individuals. The study refutes the 'barcode hypothesis' that MUPs provide individual signatures for kin recognition.
Efficiency of insect biodiversity monitoring via Malaise trap samples and DNA barcoding
The study used DNA barcoding to identify insects from Malaise trap samples, assigning species names to 35% of specimens. The workflow for semi-automated identification was efficient, but coverage gaps remain, particularly for Diptera and Hymenoptera.
Barcodes show the blood family tree
Scientists at Lund University have developed a barcode system to track the development of immune cells, revealing that stem cells undergo different stages of maturation. This discovery has significant implications for understanding leukemia and autoimmune diseases.
Revolutionary method to map brains at single-neuron resolution successfully demonstrated
MAPseq successfully demonstrates a revolutionary new way of mapping the brain at individual neuron resolution. By using RNA sequencing, researchers can rapidly and inexpensively trace the long-range projections of thousands of neurons in a single experiment.
New 'genetic barcode' technique reveals details of cell lineage
A new study introduces a 'genetic barcode' technique that tracks cell lineage using CRISPR gene editing. This method reveals the relationships between cells and accelerates our understanding of cellular processes.
DNA barcodes gone wild
A team of researchers has developed a new technology that can stitch together DNA barcodes inside cells, allowing scientists to search amongst millions of protein pairs for protein interactions. This breakthrough increases the rate of discovery without increasing costs.
Illuminating the broad spectrum of disease
Researchers developed a new method called PRISM to test potential drug compounds on cancer and other cell lines simultaneously, allowing for pooling and testing of multiple cell lines. This approach promises to accelerate the search for targeted therapies by better representing the broad genetic diversity of disease.
The four-letter code: How DNA barcoding can accelerate biodiversity inventories
A new study reveals how DNA barcoding can accelerate biodiversity inventories by using rapid publishing techniques and surveying nature reserves in just four months. The results revealed abundant biodiversity in previously understudied taxa, including the addition of 181 new spider species to the inventory list.
Unknown midge mystery solved
Researchers uncover hidden diversity in minute midges through DNA analysis and type material examination. Two new species were discovered and one misidentified species was corrected, shedding light on the fascinating world of non-biting midges.
Unplanned purchases: Why does that Snickers bar looks better the longer you shop?
A recent study published in the Journal of Marketing found that shoppers' tendency to make unplanned purchases increases as they spend more on planned items. The likelihood of an unplanned purchase can be up to 9.6% higher toward the end of the trip, depending on the shopper's budget.
Invisible inks could help foil counterfeiters of all kinds
Scientists at Northwestern University invented fluorescent inks that can be used as multicolored barcodes to authenticate products. The inks are invisible under normal light but visible under ultraviolet light, making them difficult for counterfeiters to mimic.
Go straight and publish: From Barcode of Life Data Systems to scholarly publishing systems
A recent study leveraged BOLD specimen data to uncover new records of locality, provinces, territories, and states for Nearctic species of Microgastrinae wasps. The novel workflow enables researchers to utilize the vast amount of data stored on BOLD platforms, accelerating publication and dissemination of biodiversity-related research.
Scientists devise a bar code for the bacteria that causes tuberculosis
Researchers have devised a genetic barcode that can identify different types of tuberculosis (TB) bacteria, allowing doctors to track the spread of the disease more effectively. The study found that just 62 mutations are needed to code the global family of strains, making it easier for scientists to map how TB moves around the world.
Genetic 'barcode' for malaria could help contain outbreaks
A new genetic 'barcode' for malaria parasites has been found, enabling the tracking and containment of disease spread. The barcode can identify the geographic origin of infections and monitor the spread of drug-resistant parasites.
RaDAR guides proteins into the nucleus
A Ludwig Cancer Research study has identified a novel pathway by which proteins are actively and specifically shuttled into the nucleus. The discovery reveals a precise molecular barcode that flags proteins for import and describes the biochemical interaction driving this process.
New type of barcode could make counterfeiters' lives more difficult
Scientists have developed a new type of inexpensive barcode that can be added to documents or currency to foil attempts at making forgeries. The barcodes are made from lanthanide-doped upconversion materials and are invisible to the naked eye.
Museum bird DNA 'ready for use' in Naturalis Biodiversity Center
A recent study used DNA barcoding to identify Dutch bird species with high resolution, flagging some for further investigation. The approach was particularly useful in museums, such as the Naturalis Biodiversity Center, where DNA tissue vouchers are already prepared.
Tell me your barcode, and I will tell you what palm you are
A new DNA barcode has been identified for palms, allowing for reliable species recognition and hybrid detection. The study successfully identified eight out of thirteen species and correctly identified over 82% of the individuals screened.
The value of museum collections for development of DNA barcode libraries
Researchers found that both time and body size significantly impact DNA barcode sequencing success. Larger spiders have a longer shelf life for sequencing, while nondestructive extraction techniques can improve chances of obtaining a sequence from smaller species.
Helping cancer researchers make sense of the deluge of genetic data
The Gene Expression Barcode 3.0 tool helps cancer researchers process and analyze massive amounts of genetic data from patients and mice, enabling the development of tailored treatments. The improved algorithm makes it faster and more accessible for researchers to use.
Discovering a diamondback moth: Overlooked diversity in a global pest
A recent study using DNA barcodes identified two distinct species of diamondback moths in Australia, one of which is the well-known pest and the other a newly discovered species named Plutella australiana. The discovery highlights the complexity of this global pest and its ability to evolve resistance to control methods.
Family trees for yeast cells
Researchers have developed a new method to analyse the genomes of yeast families, which is several hundred times faster than current methods. The new method uses barcode-enabled sequencing and allows for the analysis of tetrad relationships between spores, enabling the study of complex traits.
DNA barcoding alone sufficient to detect fraudulent deer products
Scientists from Hong Kong have developed a DNA barcoding method that can detect fraudulent deer products, regardless of their physical state. The method confirms that DNA barcoding alone is sufficient to detect such substitution for deer in all tendon products, except for glue.