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Hastings Center Report, July-August 2023 Issue

Experts discuss the moral implications of telemedicine on the patient-physician relationship. Telemedicine can improve care for certain patients but may also raise questions about the nature of this encounter and the importance of touch in medical interactions. The Hastings Center Report explores the complex ethical issues surrounding ...

SourceThe Hastings Center·JournalThe Hastings Center Report·TypeCommentary/editorial·DateAug 15, 2023

Game-changing potential for drug testing and cardiovascular disease treatments - Tiny Heart Model Carries Massive Implications

A miniature human heart model, approximately half a grain of rice in size, has been developed to transform drug testing and cardiovascular research. This self-paced, multi-chambered model provides real-time measurements of essential parameters, enabling unprecedented insights into heart function and diseases.

SourceThe Hebrew University of Jerusalem·JournalNature Biomedical Engineering·TypeExperimental study·DateAug 7, 2023

Fiber-infused ink enables 3D-printed heart muscle to beat

Researchers at Harvard developed a fiber-infused ink that allows 3D-printed heart muscle cells to align and contract like human heart cells, enabling the creation of functional heart ventricles. The innovation can be used to build life-like heart tissues with thicker muscle walls, paving the way for regenerative therapeutics.

A quick look inside a human being

A team of physicists and medical doctors developed a portable Magnetic Particle Imaging (MPI) scanner that can visualize dynamic processes in the human body, such as blood flow, without using radiation. The scanner is designed for real-time endovascular interventions and has the potential to change the field of intervention.

SourceUniversity of Würzburg·JournalScientific Reports·TypeExperimental study·DateJul 26, 2023

WVU researchers capture atomic view of synthetic DNA, revealing ‘molecular scissors’ that could treat disease

Researchers at WVU have developed a way to view synthetic DNA at the atomic level, enabling them to understand how to change its structure for enhanced scissor-like function. This breakthrough could lead to new technology for medical diagnoses and treatments, including potential therapies for diseases like retinal degeneration and cancer.

SourceWest Virginia University·JournalCommunications Chemistry·DateJul 24, 2023

Efficient boron neutron capture therapy for brain tumor with novel boron carrier

Researchers at Tokyo Institute of Technology developed a novel boron agent that selectively accumulates in brain tumor cells, exhibits enhanced blood retention, and can be administered at low doses. The agent, PBC-IP, shows promising results in preclinical studies, highlighting its potential for radiotherapy in treating glioblastoma.

SourceTokyo Institute of Technology·JournalJournal of Controlled Release·TypeExperimental study·DateJul 13, 2023

Updating pulse oximeters

Researchers are studying ways to update pulse oximeter technology to address limitations including overestimation in patients with darker skin tones and motion artifact. The goal is to improve the accuracy of oxygen saturation readings, particularly for diverse groups and in multiple settings.

DNA test could broaden access to cervical cancer screening

Rice University engineers developed a low-cost, point-of-care DNA test for HPV infections that can be used to screen for cervical cancer. The test, which requires just two pieces of equipment and delivers results in 45 minutes, has the potential to make cervical cancer screening more accessible in low- and middle-income countries.

SourceRice University·JournalScience Translational Medicine·TypeExperimental study·DateJun 21, 2023

Creating artificially engineered organs could become quicker and easier

Researchers have developed a new manufacturing pipeline to simplify and advance high-value manufacturing of tissue-compatible organs, reducing costs and increasing efficiency. This breakthrough aims to address the dire need for artificially engineered organs and tissue grafts, potentially saving thousands of lives in the UK.

SourceUniversity of Huddersfield·JournalAdvanced Healthcare Materials·TypeImaging analysis·DateJun 12, 2023

A Chinese Neurosurgical Journal study presents consensus on the management of aneurysmal subarachnoid hemorrhage-related hydrocephalus

Aneurysmal subarachnoid hemorrhage-related hydrocephalus is a complex syndrome that can lead to cognitive impairment and neurological damage. The new consensus guideline recommends standard-of-care approaches, including history review, head CT scans, and medications or surgical interventions to manage excessive intracranial pressure.

SourceCactus Communications·JournalChinese Neurosurgical Journal·TypeLiterature review·DateJun 12, 2023

Technology advance lays groundwork for OCT eye imaging at home

Researchers have developed a custom OCT setup that incorporates a vertical cavity surface emitting laser (VCSEL) diode, which could increase access to OCT imaging and help catch eye problems early. The system performed well in imaging the eye of a healthy volunteer and showed potential for use in biometric eye scanner systems.

SourceOptica·JournalOptics Letters·DateJun 1, 2023

New liver dialysis device shows potential to resolve liver failure in patients with acute-on-chronic liver failure

A clinical trial using DIALIVE, a novel liver dialysis device, demonstrated significant improvements in all main underlying pathophysiological mechanisms of acute-on-chronic liver failure. Treatment resulted in accelerated resolution of ACLF and sustained improvement in biomarkers.

SourceElsevier·JournalJournal of Hepatology·TypeRandomized controlled/clinical trial·DateMay 31, 2023

New framework for super-resolution ultrasound

Researchers at the Beckman Institute for Advanced Science and Technology have developed a new framework for super-resolution ultrasound using deep learning, reducing processing speeds from minutes to seconds. The new technology enables real-time blood flow visualization, overcoming challenges faced by conventional methods.

SourceBeckman Institute for Advanced Science and Technology·JournalIEEE Transactions on Medical Imaging·TypeImaging analysis·DateMay 25, 2023

Enhancing patient care by improving electronic health records: Plan outlines 3 'essential' steps

The University of Virginia Health System has developed a plan to improve the use of electronic health records, reduce clinician workload, and enhance patient care. The plan outlines three 'essential' steps for improving electronic health reforms, including implementing unique personal safety identifiers to streamline operations.

Primary care clinicians report benefits and challenges in using telemedicine during COVID-19 pandemic

A study of primary care clinicians reveals benefits and challenges of telemedicine, including ease of adoption depending on prior experiences, unclear visit triage rules, and positive impacts on physicians and patients. The technology also presents challenges such as conducting physical exams and diagnostic testing.

SourceAmerican Academy of Family Physicians·JournalThe Annals of Family Medicine·DateMay 23, 2023

New study shows noninvasive brain imaging can distinguish among hand gestures

A new study from UC San Diego shows that noninvasive brain imaging can distinguish among hand gestures with more than 85% accuracy. The research uses magnetoencephalography (MEG) to detect magnetic fields produced by neuronal electric currents, offering a safe and accurate option for developing brain-computer interfaces.

SourceUniversity of California - San Diego·JournalCerebral Cortex·TypeExperimental study·DateMay 19, 2023

Insight into brain’s waste clearing system may shed light on brain diseases

Researchers at Washington University in St. Louis have found a way to enhance glymphatic transport using focused ultrasound with microbubbles, opening new opportunities for studying brain diseases and function. The non-invasive method shows promise for potentially mitigating neurodegenerative diseases like Alzheimer's and Parkinson's.

SourceWashington University in St. Louis·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateMay 16, 2023

Gwangju Institute of Science and Technology researchers develop injectable bioelectrodes with tunable lifetimes

Researchers from GIST have developed graphene-based conductive hydrogels that are injectable, degradable, and highly compatible with biological systems. The novel electrodes outperform traditional metal electrodes in signal transmission and stability, offering promising solutions for long-term medical monitoring and treatment.

SourceGIST (Gwangju Institute of Science and Technology)·JournalSmall·TypeExperimental study·DateMay 10, 2023

Researchers overcome stem cell delivery barrier, paving the way for regenerative medicine

Scientists have developed a new method to deliver genetic information to stem cells using nanoparticles coated with a specific polymer, enabling more efficient control over cellular differentiation. This innovation has the potential to improve the efficiency and effectiveness of regenerative medicine treatments.

SourceXi'an Jiaotong-Liverpool University·JournalNano Letters·TypeExperimental study·DateMay 8, 2023

Study unlocks potential breakthrough in Type 1 diabetes treatment

Rice University scientists developed a screening technique to identify high-performing biomaterials for encapsulating insulin-secreting cells, providing long-term blood sugar level control in diabetic mice. The study's findings have the potential to open the door to a more sustainable and self-regulating way to treat Type 1 diabetes.

SourceRice University·JournalNature Biomedical Engineering·TypeExperimental study·DateApr 27, 2023

Ingestible electroceutical capsule shows promise for treating gastrointestinal conditions

Researchers from Brigham and Women's Hospital developed an ingestible capsule, known as the FLASH system, which electronically stimulates key hunger hormone ghrelin in pigs. The system has potential applications for treating gastrointestinal disorders and is a promising alternative to traditional treatments.

SourceBrigham and Women's Hospital·JournalScience Robotics·TypeObservational study·DateApr 26, 2023