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Harvard researchers publish MRI images of genes in action in the living brain

Researchers at Harvard have developed gene probe eye drops that enable non-invasive monitoring of brain activity in living organisms. The technology uses MRI to detect tissue repair and has potential applications in treating neurological diseases, diagnosing conditions, and delivering therapeutic agents to the brain.

MRI: A window to genetic properties of brain tumors

Researchers have shown that MRI can non-invasively characterize brain tumors and determine which are responsive to specific treatments based on their molecular properties. The study identified five distinct MRI features linked with particular gene expression patterns, including those associated with tumor proliferation and growth.

SourceUniversity of California - San Diego·JournalProceedings of the National Academy of Sciences·DateMar 24, 2008

MRI/PET scanner combo

The combined scanner uses a new technology to eliminate interference between MRI and PET systems, enabling simultaneous acquisition of structural and functional information. This innovation allows researchers to correlate tumor structure with functional information, providing deeper insights into cancer research.

SourceUniversity of California - Davis·JournalProceedings of the National Academy of Sciences·DateMar 6, 2008

MRE could provide a definitive diagnosis for people with muscle pain, Mayo Clinic study shows

Researchers at Mayo Clinic have developed a new imaging technology called magnetic resonance elastography (MRE) that can provide images of affected muscles with greater clarity than traditional MRI. This technology measures tissue elasticity and can detect abnormal hardening of tissues, which is a hallmark of myofascial pain syndrome.

SourceMayo Clinic·JournalArchives of Physical Medicine and Rehabilitation·DateNov 29, 2007

Research at Rice may help explain aspects of synesthesia

A Rice University research team has found that damage to the ventrolateral nucleus (VL) of the thalamus can lead to cross-wiring in the brain, resulting in synesthesia. The study, led by Tony Ro, used neuroimaging and behavioral studies on a patient with a rare stroke to demonstrate the VL's role in sensory processing.

SourceRice University·JournalAnnals of Neurology·DateSep 25, 2007

MRI finds breast cancer before it becomes dangerous

Researchers at the University of Bonn found that MRI is substantially more accurate than mammography in detecting very early stages of breast cancer, including preinvasive DCIS. The study detected 167 cases of early breast cancer, with MRI identifying 152 cases and mammography detecting only 93 cases.

SourceUniversity of Bonn·JournalThe Lancet·DateAug 10, 2007

Live broadcasts

Researchers have developed a genetically modified mouse model using the ferritin reporter gene, enabling live cell imaging via magnetic resonance imaging (MRI) without additional substances. This breakthrough overcomes limitations in detecting signal changes in tissues, such as fetal development and the central nervous system.

SourceWeizmann Institute of Science·JournalNature Medicine·DateJul 26, 2007

'Virtual' mouse brains now available online

Researchers at Duke University have developed a new method for creating ultra-high resolution 3D images of tiny mouse brains using magnetic resonance imaging. The technology allows for the detailed visualization of brain structures and their relationship to genetics, enabling scientists to study gene-brain connections.

SourceDuke University·JournalNeuroImage·DateJul 9, 2007

3-D ultrasound scanner provides in-depth view of the brain

A new 3D ultrasound scanner developed by Duke University researchers enables better brain tumor detection and minimally invasive surgery guidance. The device, inserted through a small hole in the skull, produces high-quality images of brain structures, overcoming limitations of traditional MRI and CT scans.

SourceDuke University·JournalUltrasound in Medicine & Biology·DateJun 20, 2007

Better insight into brain anatomical structures

Researchers have developed a new, biocompatible MRI contrast agent using manganese oxide nanoparticles that produces clear images of mouse brains. The agent allows for high-contrast views of brain anatomy and has potential applications in diagnosing brain diseases such as Alzheimer's and Parkinson's.

SourceWiley·DateMay 30, 2007