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Mammograms may detect some cancers that would have otherwise regressed

A study found breast cancer rates increased in women screened every two years compared to those screened once, suggesting some cancers may spontaneously regress. The findings raise concerns about the value of mammography and highlight the need for further research into breast cancer's natural history.

New technology could revolutionize breast cancer screening

A new radar breast imaging system has been developed at the University of Bristol, which uses radio waves to create a 3D image of the breast without radiation risk. The system has been trialled at North Bristol NHS Trust and shows promise in detecting abnormalities earlier than current methods.

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New tool for early diagnosis of breast cancer

Scientists have developed a new X-ray technique called Analyzer-Based X-ray Imaging (ABI) for early breast cancer detection, offering high spatial resolution and sensitivity. The technique has shown promising results in distinguishing microcalcifications and improving the definition of tumor shapes and margins.

Over-the-counter anesthetic gel puts the squeeze on mammogram pain

A new study finds that a topical application of 4% lidocaine gel significantly reduces breast discomfort during mammography. Women who received the gel reported less pain and were more likely to undergo regular screening, with 88% indicating they would definitely get a mammogram the following year.

Mammography facility characteristics associated with accuracy of screening

A study found that certain mammography facility characteristics, such as breast imaging specialists and screening/diagnostic services, are associated with improved interpretive accuracy. The analysis of 44 facilities performed over 484,463 screenings revealed variations in cancer detection rates between locations.

Adding ultrasound screening to mammography brings benefits, risks

A clinical trial found that adding ultrasound screening to mammography increases the detection of breast cancer, but also raises the risk of false positive findings and unnecessary biopsies. The study suggests that women at high risk of breast cancer may benefit from supplemental ultrasound screening.

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Mammography may be beneficial to all women, regardless of age

Researchers found that regular mammograms significantly reduce the risk of being diagnosed with advanced stage breast cancer in women over 80. Women who received mammograms were more likely to be diagnosed with early-stage disease and had a higher five-year survival rate compared to non-users.

Screening mammography in elderly patients beneficial

Elderly patients over 70 years old benefit from frequent mammograms, which can detect breast cancers earlier and reduce surgical procedures. The study found that 19 of 24 cases of breast malignancy were initially identified on screening mammography.

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Other highlights in the Feb. 26 JNCI

A large randomized trial of personalized interventions found that two behavioral interventions did not significantly increase regular mammograms in female veterans. The study's findings support the generalizability to the US female population, which has seen a decline in mammography rates. Meanwhile, another study suggests that viral D...

Hormone therapy increases frequency of abnormal mammograms, breast biopsies

A study of post-menopausal women found that hormone therapy increased the risk of abnormal mammograms and breast biopsies, while also decreasing the effectiveness of these methods for detecting breast cancer. The therapy may delay diagnosis and increase breast density, which can lead to a higher risk of breast cancer.

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Digital mammography superior to film mammography in some cases

A new study published in Radiology found that digital mammography is more accurate than film mammography for women under 50 with dense breasts. The Digital Mammographic Imaging Screening Trial (DMIST) compared the accuracy of both methods in different subgroups, confirming improved diagnostic accuracy for digital mammography in pre- an...

Health insurance co-payments deter mammography use

A study by Brown University and Harvard Medical School found that health insurance co-payments significantly reduce mammography use among women. The researchers analyzed data from Medicare managed-care plans and found a 8-11% decrease in breast cancer screening rates among women with co-payments, compared to those with full coverage.

Annals of Internal Medicine tip sheet for Jan. 1, 2008, issue

A study found that targeted digital mammography screening can be cost-effective for younger women with dense breasts, while conventional film mammography may be more effective for older women. Additionally, labeling epinephrine as a dose or ratio affected dosing errors among doctors.

Cone-Beam CT faster, potentially more accurate than conventional mammography

Researchers discovered that cone-beam breast CT provides exceptional tissue contrast and can reduce examination time with comparable radiation dose to conventional 2D mammography. The study found well-resolved images of skin, adipose, and glandular regions, as well as clear detection of microcalcifications within cancers.

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Diagnostic mammogram readings vary extensively by radiologist

A study published in the Journal of the National Cancer Institute found that diagnostic mammogram readings vary extensively by radiologist, with no explanation for the variation. Radiologists' performance was influenced by their experience, affiliation, and time spent interpreting mammograms.

Accuracy of diagnostic mammograms varies by radiologist

A nationwide study found that diagnostic mammogram accuracy depends on the radiologist reading it, with varying sensitivity and false-positive rates. Radiologists based at academic medical centers or spending most time on breast imaging performed more accurately.

'Stereo' mammography takes breast imaging to a new dimension

Stereo mammography has been shown to reduce false positives by 49% compared to standard digital mammography, potentially cutting the number of women recalled for additional tests. The technology produces three-dimensional views of breast tissue, allowing radiologists to better interpret images and detect cancer earlier.

New mammography technology improves cancer detection

A new radiological diagnostic tool called stereo mammography reduces false-positive findings by 49% and missed lesions by 40%. The technology cuts the number of women recalled for additional tests in half, eliminating anxiety for patients and their loved ones.

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City-dwelling women at greater risk for breast cancer

A study by Nicholas M. Perry found that urban women have denser breasts and are nearly four times more likely to develop breast cancer than rural women. Regular breast screening with digital mammography is advised for all women, especially those with dense breast tissue.

MRI finds breast cancer before it becomes dangerous

Researchers at the University of Bonn found that MRI is substantially more accurate than mammography in detecting very early stages of breast cancer, including preinvasive DCIS. The study detected 167 cases of early breast cancer, with MRI identifying 152 cases and mammography detecting only 93 cases.

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Additional mammogram readers improve breast cancer detection

A study published in the Journal of the National Cancer Institute found that adding readings by non-physician technologists to standard mammograms read by two radiologists increased breast cancer detection rates by 6.8%. This improvement was achieved with a minimal increase in false positives.

Breast cancer and hormone therapy -- A looking-glass mirror?

A new Kaiser Permanente study suggests a possible link between breast cancer incidence and postmenopausal hormone therapy (HT) use, but concludes that the association is complex and influenced by various factors, including mammography screening rates. Long-term HT may slightly increase breast cancer risk, particularly in younger women.

Yearly mammograms protect breast cancer survivors

A study by the Cancer Research Network found that regular post-therapy surveillance lowers the rate of death from breast cancer in older women. The researchers examined nearly 2,000 patients age 65 and older with stage I and II breast cancer and found that annual mammograms can decrease death rates.

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Mammography rates declining in the United States

A new study reveals that mammography rates have declined significantly in the US between 2000 and 2005, with a notable decrease among women aged 50-64 and higher socioeconomic levels. The decline in screening rates coincides with a reduction in reported breast cancer incidence, raising concerns about potential impact on mortality rates.

New hereditary breast cancer gene discovered

Scientists have found a new hereditary breast cancer gene, TWIST1, linked to Saethre-Chotzen syndrome, increasing breast cancer risk by nearly twenty times. Early mammograms are now recommended for young women with the syndrome to detect breast cancer at an early stage.

Annals of Internal Medicine tip sheet for April 3, 2007

The American College of Physicians released a guideline for mammography screening in women between ages 40 and 49, emphasizing the need for individualized decision-making based on risk factors. The guidelines also highlight the uncertainty surrounding long-term effects of false-positive screening results on women's behavior.

New guideline for screening mammography for women 40 to 49 years of age

The American College of Physicians recommends that clinicians assess each woman's breast cancer risk profile before making a decision about screening mammography. Women between 40-49 years old should weigh the potential benefits and harms of screening, discussing their concerns with their doctor to make an informed choice.

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Mammograms for women in their 40s should be based on individual

The American College of Physicians recommends that mammography screening decisions be made on a case-by-case basis, considering each woman's individual cancer risk and preference. The new guidelines acknowledge the benefits and harms of screening, recommending periodic assessment of breast cancer risk to inform decision-making.

Computerized reminders boost mammography screening rates

A Mayo Clinic study found that using computerized reminders can increase mammography screening rates, with 64.3% of women in the intervention group getting a yearly mammogram compared to 55.3% in the control group. The program has expanded beyond mammograms to include other preventive services.

Contrast agent puts new light on diagnosing breast cancer

Researchers have developed a new contrast agent that selectively targets and highlights malignant micro-calcifications in the breast, while ignoring similar calcifications found in benign breast conditions. This technique has the potential to improve breast cancer diagnosis by reducing false positives and increasing detection rates.

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Access to prior mammograms helps radiologists detect breast cancer

A study found that viewing prior mammograms alongside current mammograms significantly improves radiologist performance and reduces unnecessary recalls. The use of prior mammograms recorded on film in comparison with digital mammograms poses a challenge, but limiting their availability may balance medical benefits with effort.

Advances in breast imaging

Researchers at Mayo Clinic have developed a new gamma camera technique that can detect breast tumors as tiny as one-fifth of an inch in diameter with 88% accuracy. The device is sensitive enough to identify small cancers that were not found by mammography, and may be more comfortable for women due to less pressure needed during imaging.

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Health benefits, risks weighed for mammography in 40-something women

A study of 160,000 women screened in their 40s compared to those in their 50s found little change in estimated overall survival. The authors conclude that the benefits of early detection may outweigh the risks of radiation-induced breast cancer, but the uncertainty remains too great to make a definitive recommendation.

Technology can't replace doctors' judgment in reading mammograms

A recent study by Group Health Research Institute shows that computer-assisted detection (CAD) technology improves mammographic specificity by 3%, allowing 30 women to avoid further evaluation. However, CAD does not affect overall sensitivity and may lead to deferral of radiologists' own judgment.

Mobile mammography brings screening to more Native American women

A new project delivers mobile digital mammography services to remote reservations, transmitting images via satellite for real-time interpretation. The initiative aims to improve breast cancer screening and care for rural American Indian women, who face high mortality rates.

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New breast CT scanner rivals mammography

The Cone Beam Breast Computed Tomography (CBBCT) scanner produces three-dimensional pictures of breast anatomy to distinguish benign lesions from tiny cancers. The pilot study showed promising results, with one case demonstrating a cancer that was hard to detect on a mammogram.

Big bias in who gets screened for breast cancer

A study found that elderly women, those with public health insurance, and those who don't visit obstetricians regularly are less likely to receive clinical breast exams and mammogram recommendations. Regular clinical breast exams can detect breast cancer at an early stage, making them comparable to yearly mammograms.