Research on the tests that detect and monitor disease. Covers blood tests, cancer monitoring, emergency diagnostics, and new patent-pending assays.
A new study demonstrates that pooling treatment recommendations from multiple prescribers using the 'wisdom of crowds' concept can improve decisions on antibiotic prescribing and reduce overuse. Using international survey data, researchers found that groups of three or more prescribers showed significant benefits in guideline compliance.
A clinical trial is underway to test the safety and feasibility of intrapleural liposomal curcumins as an alternative to chemotherapy for malignant mesothelioma. The researchers aim to reduce toxic side-effects and facilitate early diagnosis with a special lung fluid test.
Engineers at Monash University developed a portable and cheap diagnostic that measures fibrinogen concentration in blood. This simple test can diagnose hypofibrinogenemia in critically bleeding patients anywhere in the world, reducing treatment time by up to five times.
Neural interface electrodes play a crucial role in studying the nervous system and developing potential treatments for diseases. A new set of guidelines has been established to standardize the testing of these electrodes, enabling transparent reporting and promoting an efficient scientific process.
A Dartmouth study found that involving pediatric practices in promoting private well water testing can significantly influence parental compliance. The study, which tested two interventions, showed that providing both parents and clinic access to results and follow-up reminders increased testing completion rates.
A new DNA test developed by Flinders University can accurately determine the legal status of seized ivory samples, even in highly degraded state. The technique has shown 100% identification accuracy and correct assignment in the legal status of 227 highly degraded ivories.
A Mayo Clinic study analyzed Google web searches for keywords related to COVID-19, finding strong correlations with outbreaks in parts of the US up to 16 days prior. The study's findings suggest that analyzing internet surveillance data can help predict and respond to hot spots in a pandemic.
Two new research projects will explore the use of drones for medical delivery purposes in the UK, aiming to facilitate faster and more efficient movements of medical items. The projects, funded by Innovate UK, will focus on creating standard operational procedures for drone-enabled delivery operations.
Researchers have identified phosphorus-containing compounds as markers for thyroid hormone action in tissue using non-invasive magnetic resonance spectroscopy. This allows for the measurement of hormone action in different areas of the body, potentially improving care for patients with thyroid dysfunction.
Researchers at the University of Sydney have developed a new method to predict speech perception for individual recipients, enabling personalized cochlear implant configurations. This study aims to further improve the performance of cochlear implants in noisy environments.
Researchers at McMaster University have developed a prototype for a hand-held device that can read the levels of a cancer biomarker, similar to a blood-sugar monitor. The device simplifies cancer testing by allowing patients to collect samples at home and providing accurate results in minutes.
Researchers found that a D-dimer blood test alone can accurately identify patients at risk of deep vein thrombosis (DVT), allowing for targeted follow-up with ultrasound examinations. The study suggests this simplified approach could reduce unnecessary tests and improve diagnosis accuracy.
A new test developed by Johns Hopkins University can accurately pinpoint and capture the deadliest cells in glioblastoma, a type of fatal brain cancer. The method's accuracy in predicting patient outcomes varies from 86% to 100%, suggesting its potential for developing targeted therapeutics.
Researchers have developed a new statistical model that accurately analyzes electrodermal activity (EDA) signals, providing insights into internal cognitive states and physiological processes. The inverse Gaussian model matches the physiology of sweat production and offers a principled approach to modeling EDA signals.
Researchers at University of Reading and Newcastle University found planaria can be used as a reliable alternative for testing topical skin products without harming animals. The use of fluorescent dye mixed with potential skin products shows accurate interaction with living tissue.
A new study published in JAMA Cardiology found that 30,000 out of every 100,000 stress tests performed each year were unnecessary for patients undergoing knee and hip replacement surgeries. Despite a decrease in overall stress testing since 2006, the study highlights the need for educational initiatives to improve the utilization of me...
A collection of articles reviews the literature on using isokinetic testing to measure muscle strength in older adults with conditions such as COPD and stroke. The studies provide evidence for the validity and reliability of isokinetic strength testing, but highlight limitations in responsiveness and practicality.
Researchers evaluated COVID-19 testing and positive case rates among Seattle residents with varying language backgrounds, finding significant disparities. The study suggests that language use can be used as a proxy for immigrant status to identify populations at higher risk of COVID-19 infection.
Researchers have identified 11 critical cyber vulnerabilities in SweynTooth technology, which affects at least 32 medical devices in Singapore. The Greyhound framework was designed to systematically sniff out security lapses in Bluetooth-enabled devices, with 90% of affected device manufacturers implementing preventive measures.
A new CRISPR-based diagnostic method has been developed to detect four species of the malarial parasite Plasmodium. The test uses a nucleic acid detection platform called SHERLOCK and is optimized for field conditions, with a cost of $0.61 per test.
A study of 200,000 UK Biobank blood samples found over 2,000 undiagnosed cases of type 2 diabetes, with patients waiting on average 2.3 years for a clinical diagnosis. Population-level screening using HbA1c testing could identify cases earlier and reduce complications.
Researchers are testing a digital therapeutic device that uses music and sensors to help individuals recover from stroke-induced mobility loss. The study aims to improve walking speed and community ambulation in participants, offering new hope for those affected by stroke.
Researchers have developed a painless and biodegradable patch using microneedles to diagnose conditions like prediabetes. The patch combines porous microneedles with paper-based sensors for accurate glucose monitoring.
A new study provides a framework for guideline developers to offer specific guidance on right-sizing care, including when to start and stop treatments or screening. The recommendations are tailored for adult primary care and aim to reduce unnecessary testing and treatment, improving patient outcomes and quality of life.
Researchers at the University of Turku developed a rapid point-of-care diagnostic test to detect ovarian cancer from blood samples in 30 minutes. The new test shows improved sensitivity and accuracy compared to conventional CA125 diagnostics.
Researchers found that shorter rest periods, such as zero, two, and five minutes, yield the same results when measuring blood pressure. This discovery could help improve the efficiency of blood pressure assessments in busy clinical settings.
A new study of NCAA football players has found that the age they first started playing tackle football may not affect their recovery after a concussion. The study, which involved 621 athletes, tested their symptom severity and performance on thinking and memory tests after experiencing a recent concussion.
Researchers tested using wild crop relatives in breeding programs to improve crop resilience. The results showed that these relatives provided increased resistance to heat, drought, and some diseases, making them a promising approach to address climate change adaptation. However, breeders must also consider the potential impact on indu...
A team of researchers developed an individual biocontainment unit using negative pressure to filter out viral particles, preventing environmental contamination. The device was tested with over 99.99% of virus-sized aerosols trapped, making it safer for healthcare workers.
A study found that individuals with declining kidney function starting at age 30 performed like those nine years older on certain cognitive tests 20 years later. This suggests that preserving kidney function in young adulthood may be crucial for maintaining thinking skills in midlife.
Researchers report the first effective therapy for fainting, which is caused by a fall in blood pressure and/or number of heart beats. The new treatment involves pacemaker therapy, showing a 77% relative risk reduction of fainting over two years.
A new palliative care model, known as Short-Term Integrated Palliative Care (SIPC), has been shown to improve quality of life for patients with long-term neurological conditions while reducing costs. The study found no significant difference in patient-reported outcomes between SIPC and standard care.
A new physiological test for diagnosing autism spectrum disorder (ASD) has shown promise, accurately identifying 124 of 131 children with ASD regardless of co-occurring medical conditions. The test measures metabolites in a blood sample and predicts diagnosis with minimal impact from other health issues.
Paleontologists used a new approach to estimate sexual variation in dinosaur fossils, finding patterns in size differences between males and females. The study suggests that using effect size statistics can produce accurate estimates of sexual dimorphism even with limited fossil data.
A new study from Lund University reveals a significant link between cognitive impairment and increased risk of rehospitalization and death in heart failure patients. The study, which examined 281 patients, shows that those with impaired cognitive function are more likely to experience poor outcomes.
Researchers have identified a non-invasive and targeted treatment to correct nerve damage and address the pervasive problem of fecal incontinence. Magnetic stimulation of nerves regulating muscles in the anus and rectum improves function and reduces episodes of fecal incontinence in patients.
A new device developed by Dartmouth engineers has the potential to improve patient outcomes for prostate cancer patients who undergo radical prostatectomy. The device, which uses microendoscopic electrical impedance sensing probe technology, aims to detect positive surgical margins and prevent disease recurrence.
An observational study found COVID-19 case rates increased significantly among incarcerated individuals and staff in Massachusetts jails and prisons following decarceration. Testing rates were also lower during this period, contributing to the spread of the virus.
A study by Duke University researchers found that individuals who identify with groups tend to discriminate against those outside their groups, even in non-political settings. In contrast, those who do not identify with groups are less prone to bias and make decisions faster.
A new technology allows scientists to study the role of gut bacteria in health by taking samples anywhere in the gastrointestinal tract. The non-invasive tool, a drug-like capsule, can collect intestinal fluid containing bacteria and protect it for analysis.
Researchers at Babylon have developed a new approach to AI diagnosis using causal machine learning, which enables the algorithm to consider alternative realities and improve accuracy for written test cases. This technology has the potential to augment the work of clinicians and drive better healthcare outcomes.
A non-fasting blood test, hemoglobin A1c (HbA1c), can accurately identify youth at risk for type 2 diabetes and heart disease. The study suggests using HbA1c more frequently to screen youth for diabetes and related health risks.
Research published in the American Journal of Obstetrics and Gynecology found that women who consume alcohol during early pregnancy face a higher risk of miscarriage. The study analyzed data from over 5,500 women and found an incremental 8% increase in miscarriage risk each week of alcohol use.
A new combined approach improves prediction of type 1 diabetes in high-risk children, allowing better risk counselling and early intervention. The test doubles the efficiency of newborn screening programmes to prevent life-threatening ketoacidosis.
A new DNA test can accurately identify individuals whose gonorrhea is curable with a single dose of oral ciprofloxacin, providing an alternative treatment option. The study found that all 106 subjects identified as having the wild-type gyrA serine strain were cured with the antibiotic.
A new method, nanoproteomics, captures and measures various forms of cardiac troponin I, a biomarker of heart damage. This effective test could one day provide doctors with a better ability to diagnose heart disease, the leading cause of death in the U.S.
A novel, rapid carcinogen detection method using stem cells has been developed by scientists at Okayama University. The method, which takes only one week to yield results, involves testing chemicals on healthy stem cells to see if they convert into cancerous stem cells.
A new, efficient method to detect toxic heavy metals like arsenic, cadmium, and chromium in vegetables and drinking water has been developed by researchers at the University of Johannesburg. The technique combines established methods with automation and can test for multiple metals simultaneously.
Researchers developed a blood test that can identify babies at risk of serious neurodisabilities like cerebral palsy and epilepsy just hours after birth. The test looks for specific genes being switched on or off, which may provide new targets for treating brain damage before it becomes permanent.
A new model of screening combines better risk assessment, noninvasive testing options, and targeted referrals for colonoscopy to save more lives. The American Gastroenterological Association proposes a universal approach to screening that reaches more people and offers alternatives to colonoscopy.
The study defines SARS-CoV-2 testing performance standards for safe student return to US residential campuses. It sets criteria for test accuracy and interpretation to minimize COVID-19 transmission risk.
A study published by the American Academy of Neurology found that drivers who have had a concussion take longer to regain complex reaction times, crucial for driving situations. The research suggests that traditional reaction time tests may not be the best measure of driving responsiveness and readiness.
A team of researchers has developed a multi-analyte test strip to monitor various biomarkers continuously, enabling personalized medicine. The technology combines big-data analysis with wearable sensors and minimally invasive methods.
Researchers discovered that a urine test of bicarbonate can measure CFTR function in patients with cystic fibrosis. This test may predict the effectiveness of new treatments for the disease.
A non-invasive blood test, PanSeer, can detect five common types of cancers four years before conventional diagnosis methods. The test detected cancer in 91% of asymptomatic samples and accurately identified cancer-free samples 95% of the time.
Children with low cardiorespiratory fitness are at risk for premature heart disease, type 2 diabetes, and high blood pressure. Improving CRF through regular physical activity, such as sports or high-intensity interval training, can lead to better academic achievement, mental health, and overall health.
Scientists have developed a simple clinical test, the 'enhanced paper grip test,' to assess lower limb strength and predict falls. The test shows reliability and validity in detecting muscle weakness in patients with diabetes.
A study of 449 older adults found that individuals with subjective felt memory problems also exhibited measurable cognitive deficits associated with Alzheimer's disease. The findings suggest that early diagnosis and therapy development could benefit from these results.
A new male fertility test, Cap-Score, has been developed to predict which men need treatment and which couples might have success with different forms of assisted reproduction. The test quantifies sperm capacitation ability, enabling doctors and couples to make informed decisions about their fertility.
The American Thoracic Society has published a guidance document to help clinicians restore elective in-person pulmonary and sleep services. The guidance provides recommendations for resuming services, prioritizing patients, and implementing infection control measures to mitigate the risk of viral transmission.