Articles tagged with Celiac Disease
A recent study found that most celiac disease patients do not receive adequate medical follow-up, which can lead to non-compliance with a gluten-free diet. The study suggests that gastroenterologists need to improve communication with patients to ensure timely follow-up care and improve outcomes in celiac disease.
A new study found that low rates of small bowel biopsy during endoscopy contribute to the underdiagnosis of celiac disease in the US. The study revealed a significant disparity in biopsy rates among men, women, older patients, African-Americans, and Hispanics.
Researchers developed a gluten-free pasta product from green banana flour, which tasters found more acceptable than regular whole wheat pasta. The product has less fat and is cheaper to produce, making it a potential option for patients with celiac disease.
Researchers at Mayo Clinic discovered an association between Olmesartan and severe gastrointestinal issues. Patients taking the medication exhibited symptoms similar to celiac disease, but without typical test results or response to gluten-free diets.
Researchers found that women with celiac disease experience higher rates of stress, depression, and disordered eating compared to the general population. Despite managing a gluten-free diet, they often struggle with body image, weight, and shape issues.
A new study found that many commercial beers, including some labeled as low-gluten, contain significant levels of gluten. Two beers labeled 'low-gluten' had as much gluten as regular beer, highlighting the need for accurate testing.
A new study reveals that celiac patients may unknowingly expose themselves to gluten through the use of cosmetics, highlighting a significant gap in available information. Researchers found that only two top cosmetic companies provided detailed ingredient information without identifying gluten sources.
A study found a higher prevalence of undiagnosed celiac disease in women with unexplained infertility, which was significantly higher at 5.9%. Dietary changes, specifically a gluten-free diet, improved fertility rates for these women.
A study found that most US patients with celiac disease have insufficient small intestine biopsy samples, affecting diagnosis. The research suggests that taking more than two biopsy samples can increase the correct diagnosis rate sevenfold.
A study found that celiac disease is more common among Massachusetts children born in the spring or summer, suggesting a link between gluten introduction timing and birth season. The study suggests rethinking gluten introduction for some children based on their birth season.
A new study found a strong correlation between income levels and celiac disease diagnosis accuracy, with higher-income individuals more likely to receive accurate diagnoses. The study's authors suggest that socioeconomic factors, including health literacy and access to information, may contribute to this disparity.
A new study has identified interleukin 15 as a key trigger for the development of celiac disease in genetically susceptible individuals. Blocking this molecule could potentially prevent the disease, and its effects on inflammatory intestinal diseases may also offer new insights into treating conditions like acne and rheumatoid arthritis.
Researchers identified four shared genetic risk loci for celiac disease and Crohn's disease, suggesting a common underlying mechanism. The study provides evidence that risk factors shared across related diseases can be identified by combining genetic data from clinically distinct conditions.
Researchers found that hydrolyzed wheat flour baked goods are not toxic to celiac disease patients, with some even developing subtotal atrophy without clinical complaints. The study suggests further research on therapies to reduce gluten toxicity beyond the standard gluten-free diet.
A new study published in ACS' Journal of Proteome Research found that people with symptoms of potential celiac disease may not be 'potential' patients at all. The study suggests that these individuals have the same distinctive metabolic fingerprint as those with full-blown disease who benefit from gluten-free diets.
The University of Maryland School of Medicine will establish a research enterprise dedicated to autoimmune and inflammatory diseases, including celiac disease. The $45 million gift from Ken and Shelia Cafferty will support multidisciplinary research and collaborations with the University of Maryland Institute for Genome Sciences.
Researchers found that celiac disease is on the rise, with increasing cases in the elderly, challenging the common speculation that it develops in childhood. Environmental factors may play a role in developing tolerance to gluten before an autoimmune disease sets in.
Children with celiac disease are at risk for poor bone health, but adding vitamins K and D to their diets can reduce this risk. Incorporating physical activity into daily routines also boosts bone strength and Vitamin D intake through outdoor exercise.
A new diagnostic standard based on serology alone could eliminate the need for intestinal biopsy in diagnosing celiac disease. The study finds that combinations of two serology tests can accurately diagnose or rule out the disorder in over 92% of individuals.
A team of researchers has identified IL-15 as a key player in the development of enteropathy-associated T cell lymphoma, a high-grade invasive lymphoma associated with severe celiac disease. Treatment with an antibody directed at IL-15 successfully wiped out intraepithelial lymphocytes in mice overexpressing human IL-15.
A study published in the Journal of Leukocyte Biology found that manipulating intestinal microbiota with probiotics and prebiotics could improve celiac disease quality of life. The research also discovered that different types of gut bacteria influence inflammation to varying degrees.
A gluten-free diet can rapidly increase bone mineral density in children with celiac disease, leading to complete recovery of bone mineralization. Early diagnosis and a strict gluten-free diet are critical in preventing complications such as reduced bone mineral density and osteoporosis.
Research found a modestly increased risk of death in patients with lesser degrees of celiac disease-related symptoms. The risk was highest in the first year of follow-up, with cardiovascular disease and malignancy being the main causes of death in celiac disease.
Researchers at UM Medical Center have identified haptoglobin 2 precursor as the molecular link to zonulin, a protein associated with inflammatory disorders. This discovery could lead to new treatments and diagnostic tools for celiac disease and other autoimmune conditions.
Anti-glycan antibodies are found to be a common feature of celiac disease at diagnosis, linked to severe malabsorption, and lost after long-term gluten-free diet. The presence of these antibodies is not associated with NOD2/CARD15 mutations.
A Mayo Clinic study found celiac disease has become four times more common, with undiagnosed cases associated with a nearly quadrupled mortality risk. The study suggests increased awareness is needed among physicians and patients to diagnose the condition earlier.
A study of 115 young women with iron deficiency anemia found that serological screening for H. pylori and celiac disease increased gastroscopy compliance rates. The tests were confirmed by gastroscopy, which identified IDA-related GI causes in most cases.
A recent study published in Journal of Insurance Medicine found that the economic impact of undiagnosed celiac disease is significant, resulting in cost savings for the healthcare system after diagnosis. The study suggests that increased awareness and diagnosis of celiac disease can lead to health care costs savings.
Research found that vitamin B6, folate, and vitamin B12 supplements effectively lower plasma homocysteine levels in patients with celiac disease. The study also discovered a protective role of B vitamins against the negative effects of villous atrophy on homocysteine levels.
Researchers found significant correlations between serum levels of anti-tTG IgA and anti-DGP antibodies in untreated celiac disease patients. The study suggests an immune response difference to deamidated gliadin and tissue transglutaminase, supporting the hapten-carrier theory for anti-tTG IgA origin.
Type 1 diabetes and celiac disease share common genetic mechanisms, including autoimmunity-related tissue damage and intolerance to dietary antigens, the study found. Researchers identified seven chromosome regions shared between the two diseases, suggesting a potential link in environmental triggers as well.
Researchers have made significant progress in diagnosing and preventing celiac disease, a condition where gluten triggers an autoimmune response. A new therapy, AT-1001, has shown promising results in improving intestinal permeability and reducing symptoms.
Scientists discovered seven new DNA variations linked to psoriasis, which also increased the risk of four autoimmune diseases. The study found a strong genetic component underlying these conditions, paving the way for targeted treatments.
Researchers have identified immunomodulatory anticancer drugs lenalidomide and pomalidomide as effective therapies for inducing fetal hemoglobin production in sickle-cell disease patients. Additionally, a new compound has been discovered to treat protein-losing enteropathy, a condition causing excessive protein loss from the gut.
A study found that clinicians follow depression treatment guidelines poorly, failing to address key issues like suicide risk and alcohol use. Better clinician adherence is associated with reduced persistent depressive symptoms.
A study of 34 children with autism compared to 34 without autism found no connection between the two conditions. Researchers looked for specific antibodies associated with celiac disease, but none were found in autistic children.
Researchers found a connection between celiac disease and cognitive decline in patients with documented symptoms. Three patients showed reversal of cognitive symptoms after gluten withdrawal, suggesting a potentially reversible form of cognitive impairment.
Researchers at Indiana University School of Medicine found that routine screening for celiac disease in asymptomatic children with Down syndrome can have negative consequences on their quality of life. The study suggests that the cost of screening and treatment may outweigh the potential benefits, making it a less beneficial practice.
A new enzyme, prolyl endoprotease (PEP), has been identified that can efficiently degrade gluten in the human stomach, a process previously impossible. This breakthrough offers potential relief to those with celiac disease, who currently rely on a strict gluten-free diet.
A study found that introducing gluten-containing foods to infants at 1-3 months old significantly increased the risk of developing celiac disease, compared to exposure between 4-6 months. The findings suggest that early exposure to gluten may trigger an immune response in genetically predisposed children.
A recent study suggests that patients with osteoporosis may have coexisting celiac disease, which can lead to impaired calcium and vitamin D absorption. Screening for celiac disease in patients with osteoporosis may be recommended to correct bone loss.
Researchers found that patients with osteoporosis had a significantly higher prevalence of celiac disease than those without osteoporosis. Treatment with a gluten-free diet resulted in improved bone mineral density in individuals with celiac disease and osteoporosis, making serologic screening worthwhile for this population.
A new study on celiac disease over a 52-year span reveals a significant shift in patient demographics and symptom presentation. Fewer patients are diagnosed with diarrhea, while more are discovered through screening, leading to an increase in silent diagnoses.
A recent study published in PLoS Medicine found that oats can cause intolerance in some patients with celiac disease, triggering a similar molecular reaction as wheat, barley, or rye. This means that not all patients with celiac disease may be able to safely include oats in their diet.
Researchers found that IL15 induces a series of biochemical changes in NKG2D signaling pathway converting CTL cells into Lymphokine-Activated Killer Cells. MICA molecules are present in elevated amounts in celiac patients' intestinal cells, providing a target for immune cell attacks
Researchers found a moderate link between celiac disease and schizophrenia, with individuals having celiac disease three times more likely to develop the condition. A gluten-free diet may be beneficial for those genetically prone to celiac disease but undiagnosed, according to lead author Dr. William W. Eaton.
Researchers found that individuals with celiac disease often struggle to maintain a gluten-free diet outside the home, impacting lifestyle and quality of life. Supplement users, particularly women, face challenges in evaluating and selecting dietary supplements due to confusion over dosage directions, labeling, and claims.
Researchers at Zengen discovered that synthetic alpha-Melanocyte-Stimulating Hormone (a-MSH) has an anti-inflammatory effect in celiac mucosa, which may control the inflammatory response and limit epithelial damage. This finding could lead to a medical treatment for Celiac disease, currently managed only with a strict gluten-free diet.
Researchers found that more than 1.5 million Americans suffer from celiac disease, which is triggered by the protein gluten and can cause various gastrointestinal symptoms. The study, published in Archives of Internal Medicine, used a multi-center approach to screen over 13,000 people across 32 states.
Researchers at Stanford University Hospital have discovered a bacterial enzyme that can rapidly degrade toxic fragments of gluten, potentially providing an alternative to a strict gluten-free diet. This breakthrough has the potential to improve the quality of life for millions of Celiac disease patients worldwide.
Researchers at Stanford Medicine identified a protein fragment called gliadin as the cause of gluten intolerance. They also proposed using a dietary enzyme to break down the fragment into harmless bits, offering hope for future treatment.
Celiac disease patients have higher zonulin levels, which contribute to intestinal permeability and immune system modulation. Increased zonulin is also linked to other autoimmune disorders such as diabetes, multiple sclerosis, and rheumatoid arthritis.
A recent study by Wake Forest University Baptist Medical Center reveals that celiac disease is not as rare in the United States as previously believed. The condition affects an estimated 1 in 150-200 people in Europe and can be asymptomatic for many years, then trigger symptoms with exposure to gluten.
A study of 40 newly diagnosed celiac disease patients found that those with total mucosal villous atrophy had lower erythrocyte folate and serum ferritin values, but no significant differences in nutritional status among other groups. After a gluten-free diet, most abnormal biochemical values normalized.
Children and adolescents with celiac disease have significantly lower lumbar spine and whole-body bone mineral density than healthy peers. A gluten-free diet rapidly increases BMD, leading to complete recovery of bone mineralization, emphasizing the need for early diagnosis and treatment.