Articles tagged with Covid 19
Researchers developed artificial lymphoid organ-chips to recreate human immune system's response to booster vaccines. The technology could potentially be used to evaluate the likely effectiveness of new protein and mRNA-based booster vaccines for COVID-19 and other infectious diseases.
Researchers developed a monoclonal antibody called SC27 that targets multiple parts of the SARS-CoV-2 spike protein, including conserved sections. The antibody shows promise against various COVID-19 variants and related coronaviruses, potentially benefiting immunocompromised patients
A new framework from a global team of scientists aims to overcome translational hurdles in nanomedicine development. The DELIVER guidelines provide early-stage recommendations for maximizing clinical translation and enabling the successful development of new nanomedicine treatments.
The COVID-19 pandemic has led to a decrease in cancer diagnosis rates in the US, according to a new study. Despite improved trends in 2021, the rates remain lower than expected, exacerbating the existing deficit of diagnosed cases from 2020.
A study by the University of Notre Dame found that virtual learning led to a significant increase in chronic absenteeism, particularly in school districts with higher poverty rates. This resulted in lower test scores, reduced social interactions, and decreased high school graduation rates. The research suggests that students from vulne...
Researchers will analyze hMPV infection rates among infants and young children to understand its impact across different age groups. The study aims to provide critical insights into changing landscape of pediatric respiratory infections.
A new study by Mass General Brigham has found that obesity may be an important risk factor for infection from the virus that causes COVID-19. Individuals with obesity were 34% more likely to become COVID positive after reported exposure than those without obesity, indicating a possible link between obesity and increased transmission risk.
A team of researchers from Osaka University has pinpointed the B cells responsible for boosting COVID-19 immunity after vaccination. They found that activated atypical B cells are the main responders to mRNA vaccines, providing a new way to assess vaccine response and underlying biology.
A recent study suggests that starting antiviral treatment as late as 14 days after COVID-19 infection can still provide benefits for immunocompromised patients. The research found that drugs like paxlovid and molnupiravir can inhibit virus replication, even if initiated up to 14 days after infection.
Researchers at UT Austin have developed a broadly neutralizing plasma antibody called SC27 that can neutralize all known COVID-19 variants. This discovery was made possible by the technology of Ig-Seq, which provides a closer look at the antibody response to infection and vaccination.
A recent systematic review and meta-analysis of 28 studies with 1.2 million participants found that wearable technology can accurately detect conditions such as heart rate variability, blood pressure, oxygen levels, sleep quality, skin temperature, hydration, and stress levels. The study suggests that wearable activity trackers could r...
A study analyzing 47 fatal COVID-19 cases reveals two distinct disease pathways: one characterized by high viral load and low inflammation, the other by exacerbated lung inflammation. The findings suggest that understanding these molecular mechanisms can inform treatment decisions for critical cases.
This study found modestly increased risks of inflammatory bowel disease and bullous skin disorders in hospitalized patients infected with the Omicron variant. Booster vaccination mitigated long-term autoimmune sequelae risk.
A recent study led by Brigham and Women's Hospital found that semaglutide reduced deaths from cardiovascular disease and infections, including COVID-19, in obese and overweight patients. The study involved over 17,000 participants and showed a 19% lower overall death rate compared to placebo.
A new study from Tulane University found that state-level COVID-19 vaccination mandates increased vaccine rates among health care workers by 3-4%, with improvements seen in states that required vaccinations without opt-outs. The policy was particularly effective among health care workers between the ages of 25-49 years.
New studies show semaglutide reduces all-cause death, CV death, and non-CV death in people with overweight or obesity and established cardiovascular disease. The medication also improves heart failure symptoms and physical limitations in those with obesity-related HFpEF, regardless of sex.
A new substudy of the SELECT Trial found that semaglutide reduced rates of all-cause death, CV death, and non-CV death, including death from COVID-19, in patients with overweight or obesity and established cardiovascular disease without diabetes. Semaglutide also showed protective effects against COVID-19-related adverse events.
A new smart mask prototype, EBCare, analyzes chemicals in exhaled breath in real-time, offering personalized health monitoring for respiratory ailments like asthma and COPD. The device's self-cooling system allows for daily wear, while its low cost makes it a promising tool for remote health assessments.
A study analyzed news reports on scientific evidence, sources of authority, and limitations for three unproven therapeutics. It found that experts' opinions were often cited over scientific publications, and non-experts made claims about safety and efficacy.
A new study by the University of Leeds has found that British Muslims faced significant challenges accessing palliative care services during the COVID-19 pandemic. The research highlighted the need for culturally aware healthcare policies and greater inclusion of minority groups in decision-making processes to address these inequities.
Researchers in China used a scenario experiment to test messaging strategies on COVID-19 vaccine uptake. The study found that emphasizing personal risk rather than personal gain or community benefits was most effective in persuading people to get vaccinated.
Researchers discovered that the blood coagulation protein fibrin causes unusual clotting and inflammation in COVID-19, suppressing the body's ability to clear the virus. A promising therapeutic strategy has been identified, targeting fibrin to combat these deleterious effects.
A new study analyzing maternal mortality data finds that COVID-19, not restrictive abortion laws, drove a decline in maternal deaths after the Dobbs decision. The researchers adjusted for statistical artifacts from the pandemic to reveal a more accurate picture of maternal mortality trends.
A new NIH-funded study found minor changes in youth mental health overall, but significant variations depending on age, race, gender, and pre-existing mental health. Children with clinically significant problems before the pandemic improved, while others experienced declines or no change.
A recent study analyzing electronic medical records found obese individuals have a 34% increased odds of SARS-CoV-2 positivity. The research highlights obesity as a significant transmission risk factor for the virus among exposed individuals, regardless of age or sex.
A recent study by University of Missouri researchers found that giving nurses massages during their shifts can reduce physical aches and pains while improving mental rejuvenation. The study's lead researcher aims to create a healthier work environment where nurses are excited to remain in the profession long-term.
A longitudinal cohort study found differential susceptibility and resilience for mental health problems during the pandemic associated with prepandemic mental health and sociodemographic characteristics. The study's findings have implications for recovery and may provide novel insights into causes of youth mental health problems.
Patients with post-COVID-19 mRNA vaccination myocarditis show lower cardiovascular complications at 18 months compared to those with conventional myocarditis. However, affected patients may require medical management for several months after hospital discharge.
Researchers found a specific deletion in the spike protein that enhances the virus' ability to infect brains of mice, which could help understand 'long COVID' and develop treatments. The study suggests viruses with this deletion can traffic from the lung to the brain, leading to neurological symptoms.
Researchers found that intensive outpatient group- and family-based CBT that integrates telehealth can lead to significant improvements in pediatric anxiety and OCD symptoms. The hybrid model showed lasting gains for children even after treatment ended, with most families continuing to meet with clinicians after discharge.
New evidence suggests masks can reduce transmission, but behaviors like avoiding crowds also play a role. Experts emphasize the need for multi-measure approaches to public health.
The Wake Forest Institute for Regenerative Medicine is part of a new $18 million NSF initiative, COMPASS, aimed at enhancing global pandemic prediction and prevention capabilities. The collaboration will focus on understanding pathogen emergence and training the next generation of scientists to tackle this critical challenge.
A new study of 18 million people reveals a higher incidence of mental illnesses for up to a year following severe COVID-19, particularly in unvaccinated individuals. Vaccination appeared to mitigate the negative effects of COVID-19 on mental health.
A study published in the Journal of the American Medical Association identified the most common long COVID symptoms in school-age children and adolescents. The researchers created indices to guide research and diagnosis, highlighting differences between boys and girls in symptom profiles.
A recent study found that the COVID-19 pandemic exacerbated the gap in life expectancies between Black and white men, with homicide rates contributing significantly to this disparity. The analysis revealed that homicides carried a disproportionate impact on life expectancy among young men, particularly Black men.
A cohort study found elevated depression and anxiety levels in unvaccinated people with COVID-19 diagnosis compared to before or without the virus. Vaccination was associated with lower incidence of mental illnesses after hospitalization for COVID-19.
The study identified common symptoms for school-age children (headache, trouble sleeping) and adolescents (daytime tiredness/sleepiness, body pain), with 14 overlapping symptoms between the age groups. The research indexes provide a framework for studying long COVID in youth.
A recent study by New York University reveals that nearly 90% of NYC transit workers have experienced harassment or assault, with women facing higher rates. The survey found that public-facing transit workers, including bus and subway staff, are disproportionately targeted.
Researchers developed a tool to identify high-risk children and adolescents with pediatric postacute sequelae of SARS-CoV-2 infection (PASC), also known as long COVID. The study found that symptoms differed by age group, with some similarities but distinct patterns across childhood ages.
A cross-sectional study found that school districts using virtual learning during the pandemic had substantially higher chronic absenteeism rates compared to those with in-person learning. The study highlights the need for policymakers to develop strategies to reduce chronic absenteeism and utilize virtual learning effectively.
A systematic review suggests a Mediterranean diet may lower COVID-19 infection risk. The study found no evidence that the diet affects symptom severity or illness outcomes.
A comprehensive national study on long COVID in children found that the virus causes tangible and pervasive symptoms, with some children experiencing severe disabilities. The study analyzed data from over 5,000 children and found significant differences in symptoms between infected and uninfected kids.
A new measure identifies school-age children and adolescents with the highest chances of having Long COVID based on long-term symptoms. Researchers found that prolonged symptoms affect almost every organ system, with distinct patterns in children and teens, highlighting the need for further study and monitoring.
Researchers developed a new 'pan-pathogen' deep sequencing approach to capture multiple bacterial strains simultaneously. This method enables faster and more comprehensive tracking of antibiotic-resistant bacteria, potentially preventing and managing common hospital infections quicker.
A study by Texas A&M University found that Americans want their state governments to reduce Medicaid's administrative burden, allowing more people to enroll. The survey, which assessed burden tolerance during the pandemic, showed broad support for burden reduction, with bipartisan agreement on the need for easier enrollment processes.
A new study explores how older adults in a South Florida retirement community coped with the pandemic, finding they grew stronger and more resilient. Participants discovered new interests, deepened relationships, and used technology to adapt, leading to increased confidence and life appreciation.
SARS-CoV-2 uses machinery of defense cells to induce expression of unproductive isoforms of key antiviral genes, disrupting normal protein production and immune response. The study provides fundamental information on potential targets for antiviral medications and immunomodulatory interventions.
Researchers found that COVID-19 proteins can lower cortisol levels in the brain, leading to a heightened stress response and inflammation. The study suggests that this phenomenon may contribute to the neurological symptoms of Long COVID, including fatigue, depression, and memory problems.
The study found that parents experienced significant stress due to the transition to virtual learning, with many reporting difficulties in monitoring their children's work and managing their own schedules. However, some parents reported positive experiences with virtual learning, particularly for students with special needs, highlighti...
Researchers at Rice University and Northeastern University have made a discovery in the fight against COVID-19, uncovering new insights into how the virus infects human cells and can be neutralized. They found that antibodies targeting a specific part of the spike protein can bind to it and prevent the virus from entering human cells.
A new study by Yale researchers suggests that long COVID has caused extensive work time loss for many Americans, with nearly 14% not returning to work within three months. The study also found that participants experiencing five or more symptoms were twice as likely to be out of work.
A study reveals that memories of the COVID-19 pandemic lockdowns predict declines in psychological well-being among children and adolescents. The research found that adolescent females fared the worst, with memories containing more factual information about COVID-19 predicting more robust declines in mental health.
Researchers have discovered a new regulator affecting immune cells, which could lead to treatments reducing inflammation in diseases such as arthritis and severe COVID-19. The study found that the regulator, MICL, plays a key role in regulating inflammation in these diseases.
A new study provides first-of-its-kind data on the pharmacokinetics and safety of intravenous remdesivir in treating SARS-CoV-2 coronavirus in pregnant women. The research reveals that no dose adjustments are necessary for remdesivir when used in pregnant women, with no safety concerns or adverse pregnancy outcomes identified.
A computer algorithm has achieved a 98% accuracy in predicting different diseases by analyzing the color of the human tongue. The proposed imaging system can diagnose various health conditions, including diabetes, stroke, and COVID-19, using a simple and affordable method.
A recent NIH-supported study found that standard lab tests may not effectively diagnose long COVID due to the lack of validated clinical biomarkers. Researchers suggest the development of novel laboratory-based tests to better understand the pathophysiology of the condition.
A new study reveals that Black mental health professionals experience high rates of burnout and racial trauma, with higher levels of social support and resilient coping predicting lower levels of these negative impacts. The researchers suggest recruiting more Black persons into the mental health professions as a way to build trust with...
A new study found that routine laboratory tests are not reliable for diagnosing Long COVID, with no biomarker among 25 clinical laboratory values providing a clinically useful diagnosis. The researchers suggest treating symptoms rather than relying on lab results to diagnose the condition.
The study analyzed 21,031 vascular surgeries and found that the number of procedures has continued to decrease, particularly for younger and minority patients. The drop in vascular surgeries has been attributed to various factors, including elective surgery cancellations and resource scarcity during the pandemic.
A new study published in Andrology has found that patients with lower testosterone levels tend to have short little fingers, which is associated with an increased risk of severe Covid-19. The research suggests that testosterone may reduce inflammation in the lungs and other organs, providing a protective effect against severe illness.