Articles tagged with Covid 19
Researchers have found that a prostate cancer drug called proxalutamide can block SARS-CoV-2 viral entry and reduce inflammation. The compound works by binding to androgen receptors, inhibiting levels of TMPRSS2 and ACE2, and blocking infection.
A long-term study of nearly 2,400 solid organ transplant recipients found that COVID-19 vaccination significantly reduced hospitalization rates, with a 75% decrease in later omicron waves. Despite this, post-vaccination SARS-CoV-2 viral infections remain common, highlighting the importance of vaccination in high-risk populations.
A new study found that individuals exposed to common cold-causing coronaviruses have immune responses that may protect them from future SARS-CoV-2 infections. Researchers hope this insight will inform global infectious disease outbreak preparedness and vaccine development.
A historical analysis of Bern Maternity Hospital data showed a notable surge in low birth weight and stillbirth rates coinciding with the 1918 'Spanish flu' pandemic. Researchers found that mothers exposed to the pandemic had a higher risk of stillbirth, highlighting the potential impact of pandemics on infant health.
A recent study found that despite their high resilience levels, nurses considered leaving nursing at a higher rate during the COVID-19 pandemic. The study also showed that job satisfaction and work demands played significant roles in shaping intentions to leave nursing.
Researchers at Martin-Luther-Universität Halle-Wittenberg have developed a new method for detecting SARS-CoV-2 using MALDI-TOF mass spectrometry, which takes just two hours from swab to result. The approach can also detect other pathogens and is more flexible than existing PCR tests.
A new study found that around one in five people with compromised immune systems have no COVID-19 antibodies after three or more vaccinations. The MELODY study identified specific groups at higher risk of not producing antibodies, highlighting the need for targeted interventions and booster vaccines.
A UCF researcher is developing a new antibiotic to treat tuberculosis and related lung infections. The team aims to create potent antimycobacterial agents that can be administered orally and target drug-resistant strains.
Researchers found that engaging in activities, expanding social networks, and using technology can lower the risk of loneliness among elderly. However, several risk factors including older age, vision impairment, and depression increased loneliness likelihood.
A new study from UC Davis economists shows that immigration to the US did not displace U.S.-born workers in key job sectors. Instead, jobs often filled by migrants remained unfilled, highlighting the need for immigrants to bolster the labor market.
Researchers found that US physicians propagate COVID-19 misinformation about vaccines, treatments, and masks on large social media platforms. A wide reach was observed among the physicians based on their number of followers.
A study found that adolescents from low-income families gained more weight during the pandemic, with girls experiencing accelerated weight gain. The researchers tracked over 400 low-income Hispanic families and compared their weight gain to a cohort of wealthier families.
Scientists have discovered that SARS-CoV-2 can infect cells using multiple entry points beyond ACE2, explaining its ability to jump between species. This finding highlights the need for continued monitoring of coronaviruses and their potential to cause future pandemics.
Researchers found significant increases in body mass index among US youth during the COVID-19 pandemic, with effects most pronounced in low-income youth. The study highlights how preexisting social inequalities were exacerbated by the pandemic, leading to greater weight gain among vulnerable populations.
A Swansea University study explores the rationale behind the UK's COVID-19 shielding policy for clinically vulnerable individuals, finding it was an untested strategy based on risk mitigation rather than evidence-based intervention. The research reveals challenges in implementing the policy and its impact on organizations and populations.
A new UC Berkeley study explores how public psychiatric healthcare workers in metro Johannesburg coped during the COVID-19 pandemic, revealing seven major coping mechanisms that preserved well-being and improved patient outcomes.
A new study reveals that most Canadians now have hybrid immunity against SARS-CoV-2, with infection-acquired seroprevalence rising dramatically after the Omicron variant circulated in Canada. The study found that younger age groups showed faster increases in infection-acquired immunity, reaching over 75% by March 2023.
A panel of genetically diverse mice has been created to accurately model the variable human response to SARS-CoV-2 infection. The mice exhibit different levels of disease severity, ranging from asymptomatic to lethal, and can help scientists discover biomarkers of disease severity and evaluate countermeasures.
A new research case study published in The Lancet highlights the need for greater awareness of the 'blue legs' symptom associated with Long Covid. Acrocyanosis, a venous pooling of blood in the legs, can be a symptom of dysautonomia and postural orthostatic tachycardia syndrome (POTS) in patients with Long Covid.
Researchers found that COVID-19 vaccination generates antibodies in pregnant people that cross the placenta and protect their newborns against severe COVID-19 disease. Booster doses also increase maternal and newborn immune defenses against COVID-19, supporting the use of vaccination during pregnancy.
A new study by Penn Medicine found that the discontinuation of pandemic-related SNAP benefits led to a significant increase in food insufficiency in the US. The study found that households affected by the benefit cuts experienced a 21% relative increase in both food insufficiency and food insufficiency among children, affecting over 2 ...
Pregnant individuals who received a full course of COVID-19 vaccination and a booster have the strongest immune protection from the disease. Boosting after previous infection increases antibody levels in both mothers and newborns, providing maximum possible protection to infants as SARS-CoV-2 evolves.
A new study reveals that patients hospitalized with COVID-19 had a higher in-hospital mortality and persisted at 30 days, 90 days, and 180 days after discharge. The risk of death was nearly twice that observed in those who were discharged alive from an influenza-related hospital admission.
Following the COVID-19 pandemic, gastrointestinal viruses such as norovirus and adenovirus remained at very low levels for nearly 2 years. However, they surged back to pre-pandemic levels in late 2022, with adenovirus F40/41 increasing by two-fold.
A multicenter study found that long COVID symptoms can emerge months after infection and persist for at least a year in about 16% of cases. The study highlights significant impacts the epidemic has had on the US healthcare system and emphasizes the need for further research into post-COVID conditions.
Recent studies have found no link between COVID-19 vaccination and sudden cardiac arrest in athletes. However, a small decrease in VO2 Max has been observed after vaccination, which may be temporary and have minimal clinical relevance.
A team of investigators developed a novel technology to diagnose immunothrombosis, a major cause of morbidity among patients with sepsis or severe COVID-19. By measuring thrombin activity through breath gas, they can provide unprecedented knowledge of key enzymatic activity anywhere in the body.
A new Northwestern Medicine study measures resilience in biomedical scientists during COVID-19, revealing that resiliency did not guarantee career advancement. The study found that women scientists faced greater household responsibilities and social pressure to advance their careers, leading to significant career setbacks.
A study by Children's Hospital of Philadelphia found that COVID-19 affects mitochondrial function in multiple organs beyond the lungs, leading to long-term damage. Mitochondrial gene expression was suppressed in the heart, kidneys, and liver, while recovering in the lungs.
Researchers at TUM develop an RNA agent for a lung spray that slows macrophage activity, reducing lung inflammation and fibrosis. The active substance RCS-21 is delivered via an inhaler through a special sugar molecule, showing promise in treating acute inflammatory lung damage.
Researchers found that modulating type 1 Interferon (IFN-I) signaling reduces SARS-CoV-2 replication and inflammation in rhesus macaques, offering new treatment strategies for COVID-19. The study also showed a significant reduction in viral loads with IFNmod treatment.
The study found that receiving videos or reminders increased consumption of media content about the issue, increased knowledge about available resources, and reported use of some resources in response to violence. However, long-term attitudes towards gender and marital equity remained unchanged.
A large study found that fully vaccinated individuals have lower concentrations of inflammatory markers than unvaccinated participants after symptomatic COVID-19 infection. This suggests that vaccination significantly reduces morbidity and mortality by reducing elevated levels of cytokines and chemokines.
A WVU study found that U.S. cities with new professional sports teams saw increased influenza mortality rates, with the NHL teams causing the largest increase. The researchers analyzed data from 122 cities and controlled for factors like population and temperature to find a significant correlation between team arrival and flu deaths.
A new adjuvanted intranasal vaccine has shown promise in protecting both young and old mice against SARS-CoV-2 infection. The vaccine combines an RNA-based molecule with a nanoemulsion, resulting in a strong immune response.
A Swansea University-led study found that Welsh breastfeeding rates increased during the pandemic, with a significant correlation between mothers' intention to breastfeed and exclusive breastfeeding duration. The study proposes targeted interventions during pregnancy and policies to support families to improve breastfeeding duration.
A new study found an increase in precocious puberty diagnoses among girls during the COVID-19 pandemic due to poor lifestyle changes. Girls with higher body mass index scores were more likely to be diagnosed with early puberty, suggesting a link between rapid weight gain and advanced pubertal development.
A large head-to-head comparison study of the Moderna and Pfizer-BioNTech vaccines found that the Moderna vaccine was associated with a slightly lower risk of adverse events for older adults. The study also showed that the Moderna vaccine was linked to a 4% lower risk of pulmonary embolism and a 15% lower risk of diagnosed COVID-19.
Researchers have discovered two major mechanisms that contribute to the high risk of complications from lung infections in individuals with Down syndrome: poor ciliary function, which impairs the respiratory tract's ability to clear mucus and viral particles, and immune hyper-reactivity, which leads to an overactive immune response. Th...
A study published in PLOS ONE found a significant surge in bird feeding interest worldwide during the pandemic, with countries having higher bird diversity exhibiting more Google search activity. The researchers analyzed data from 115 countries and found an average increase of 511 bird species in countries with higher search interest.
A team at Sandia National Laboratories has created a new way of testing personal protective equipment (PPE) that is faster and more comprehensive. They developed two human models: one for the face and another for the entire head, allowing for more realistic testing of mask performance. The new method also includes automated donning and...
Frequent teamwork is associated with greater effort among women and white men, while other factors vary among genders and ethnoracial groups. Workplace social dynamics are a key condition linked to worker effort, with additional differences seen between white and non-white workers.
Researchers developed a peptoid-based therapy that effectively inactivates three enveloped viruses, including Zika, Rift Valley fever and chikungunya virus, by disrupting their membranes. The approach targets specific lipids, allowing for preferential attack on the invader rather than the host.
A Netherlands cohort study has revealed that healthcare workers who engaged in nose-picking were at a higher risk of contracting SARS-CoV-2 during the pandemic. The study emphasizes the significance of proper hygiene practices among healthcare professionals to prevent COVID-19 transmission.
Researchers found a significant increase in global bird feeding interest during COVID-19 lockdowns, with dramatic increases in search terms like 'bird feeder' and 'bird food' across 115 countries. The study suggests that this trend may have implications for avian communities, migration patterns, and biodiversity.
A recent study found that employees tend to be less productive in the afternoons, especially on Fridays, with increased typing errors and reduced computer activity. Flexible work arrangements like hybrid work or a four-day week may help mitigate this decline in productivity.
A new study by MU researcher Roy Thompson found that immigrant nurses in long-term care facilities often have more 'human capital' than their American-born counterparts, including language skills and additional certifications. This diversity can improve patient health outcomes and create a more equitable workforce.
Biologists argue that building on genomic sequencing momentum is critical in society's response to future pandemics. The technology improved during the COVID-19 pandemic, but gaps remain in global infrastructure and data sharing.
A study from the University of Gothenburg found that even vulnerable people with compromised immune systems achieved good antibody levels after three doses of COVID-19 mRNA vaccine. This is particularly significant for those at risk of severe Covid-19, as they showed catch-up antibody responses and high levels of hybrid immunity.
A new study found a significant decline in early-stage cancer diagnoses in the US during the first year of the COVID-19 pandemic, with the largest decrease seen among stage I cancers. The study suggests that these declines may be due to decreased screening services and delayed medical care during the pandemic.
A study found COVID-19 vaccination coverage was high among healthcare workers and older adults, but low among non-priority recipients. The main reason for wanting to be vaccinated was to prevent self-infection and protect family members.
A global study analyzed data from over 6,600 families with a child with a neurodevelopmental condition to understand how the COVID-19 pandemic impacted their anxiety levels. The results show that anxiety increased for parents and children at the beginning of the pandemic, but decreased for children as they returned to pre-pandemic levels.
The NIH has launched phase 2 clinical trials to evaluate at least four potential treatments for long COVID, including drugs, biologics, and therapies. These trials aim to identify effective treatments swiftly by evaluating multiple treatments simultaneously.
A study of 2,900 participants found that anxiety is a key factor in the mental health impacts of the pandemic, with women coping better when supported by friends and family. Men experience higher psychological stress due to job insecurity and unemployment.
Researchers developed an AI-based system using wastewater data from US counties to predict COVID-19 hospital admissions. The model achieved accurate predictions, allowing public health officials to prepare for and manage pandemic waves.
A new study found that federal government's Paycheck Protection Program (PPP) loans improved staffing levels at nursing homes during the pandemic. Loans reached understaffed facilities, increasing staff hours among certified nursing assistants and licensed practical nurses.
A new study by Texas A&M University researchers found substantial public support for shifting administrative burdens away from individuals and improving communication on Medicaid enrollment procedures. The survey-based study showed that people with experience in Medicaid, political liberalism, and those who struggle with administrative...
Researchers isolated antibodies from a vaccinated SARS patient that can stop nearly all related coronaviruses tested. The most powerful antibody, E7, neutralizes SARS-CoV and Omicron variants, showing a unique mechanism of binding to the virus's spike protein.
Researchers investigated the inactivation efficacy of different UV wavelengths against SARS-CoV-2 Omicron variants, finding similar inactivation properties across various wavelengths. The study highlights the potential of far-UVC light as a safe germicidal option for mitigating airborne virus transmission.
A study analyzing wearable device data from over 190,000 users found that vaccinated individuals experience less severe COVID-19 symptoms and recover faster. Vaccination reduces the risk of severe disease, hospitalization, ICU admission, and death.