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Researchers discover gene that causes deafness

Researchers at the University of Cincinnati have identified a genetic mutation responsible for deafness and hearing loss associated with Usher syndrome type 1. The discovery of the CIB2 protein provides new insights into the mechanism of mechano-electrical transduction, which converts mechanical energy into sound.

SourceUniversity of Cincinnati·JournalNature Genetics·DateSep 30, 2012

Contributions of deaf people to entomology: A hidden legacy

This review paper reveals the achievements of deaf and hard-of-hearing scientists who communicated their discoveries in entomology, including Charles Bonnet and Charles Darwin. The authors highlight the struggles and triumphs of these pioneers in light of their isolation from the Deaf community.

SourceBrill·JournalTerrestrial Arthropod Reviews·DateSep 26, 2012

New clues to human deafness found in mice

The FGF20 gene is required for proper development of the mouse inner ear, and its inactivation leads to a loss of outer hair cells. Researchers found that FGF20 signaling must occur on or before day 14 of embryonic development to produce a normal inner ear.

SourcePLOS·JournalPLOS Biology·DateJan 3, 2012

Critical molecules for hearing and balance discovered

Researchers have identified long-sought genes in sensory hair cells of the inner ear that are essential for converting sound waves into electrical signals. By introducing these genes into deaf mice, scientists were able to restore electrical signals and potentially reverse a type of deafness, paving the way for a gene therapy trial.

SourceBoston Children's Hospital·JournalJournal of Clinical Investigation·DateNov 21, 2011

Helping deaf people to enjoy music again

A two-year project aims to improve music appreciation in cochlear implant users through innovative music workshops and a computer tool kit of listening exercises. Researchers will develop materials and compositions specifically designed for cochlear implant users, aiming to boost self-confidence and enjoyment.

Falling on deaf ears

Researchers at UCL discovered 'inattentional deafness' when participants focused on tasks requiring high concentration. In experiments, only 2 out of 10 participants missed the tone when judging colors, but 8 out of 10 failed to notice it during length-discrimination tasks.

Comparable effectiveness shown for 2 common sudden deafness treatments

A large clinical trial has shown that direct injection of steroids into the middle ear is equally effective as oral steroids in restoring hearing levels in patients with sudden deafness. The study results, published in the Journal of the American Medical Association, have implications for treatment options and cost-effectiveness.

For hearing parts of brain, deafness reorganizes sensory inputs, not behavioral function

A study by researchers at Virginia Commonwealth University finds that deaf animals' brains reorganize sensory inputs to preserve their behavioral functions. The research provides insight into brain reorganization following sensory loss, potentially informing the development of more effective rehabilitative medicine for deaf patients.

SourceVirginia Commonwealth University·JournalProceedings of the National Academy of Sciences·DateMay 10, 2011

Words help people form mathematical concepts

Researchers found that deaf people in Nicaragua who used self-developed gestures, called homesigns, had difficulty understanding the value of large numbers. In contrast, those who acquired conventional sign language as children were able to learn the meaning of large numbers.

SourceUniversity of Chicago·JournalProceedings of the National Academy of Sciences·DateFeb 7, 2011

Researchers reveal function of novel molecule that underlies human deafness

Researchers identified miR-96 as a key regulator of auditory sensory hair cell development. The study revealed that mutations in this microRNA prevent the normal progression of hair cell development, leading to deafness. This breakthrough discovery opens new avenues for developing treatments for progressive hearing loss and deafness.

SourceUniversity of Sheffield·JournalProceedings of the National Academy of Sciences·DateJan 21, 2011

Bone-anchored hearing aids help youth with single-sided deafness

Bone-anchored hearing aids significantly improved scores on both hearing tests and questionnaires for children with single-sided deafness. The complication rate was 17%, but the treatment has been shown to be beneficial in counseling children and their families regarding treatment options.

SourceJAMA Network·JournalArchives of Otolaryngology - Head and Neck Surgery·DateFeb 15, 2010

Active hearing process in mosquitoes

A mathematical model explains how male mosquitoes can hear the faintest beats of a female's wings while resisting loud noises. The model reveals that scolopidia located toward the tip of Johnston's organ contribute to mechanical amplification.

SourceUniversity of Bristol·JournalJournal of The Royal Society Interface·DateNov 19, 2009

Gene discovery reveals a critical protein's function in hearing

Researchers identified a new protein that protects sensory cells in the ear, crucial for maintaining potassium balance and preventing intoxication. The study found mutations in the claudin-9 gene lead to functional defective sensory cells, highlighting the importance of this protein in hearing.

SourcePLOS·JournalPLOS Genetics·DateAug 21, 2009

Found: A gene that may play a role in type 1 diabetes

Scientists at Stanford University have identified a gene variant that may play a role in the development of type 1 diabetes. The study found that cells in the pancreatic lymph nodes produce two forms of the Deaf1 gene, one functional and one nonfunctional. Increased levels of the nonfunctional variant were found in people with type 1 d...

Scaling the wall of deafness

A new study by Prof. Karen Avraham at Tel Aviv University has discovered that microRNAs are involved in the development of deafness, opening up new avenues for treatment and potential cure. The researchers found that microRNAs help regulate cell functions in the ear, and their loss can lead to progressive hearing loss.

SourceAmerican Friends of Tel Aviv University·JournalProceedings of the National Academy of Sciences·DateApr 14, 2009