Articles tagged with Fibrosis
Researchers found that a specific adult stem cell travels to the lung through the bloodstream and produces collagen, leading to scar tissue formation. Blocking this mechanism may reduce pulmonary fibrosis, offering new treatments for related disorders like rheumatoid arthritis.
Researchers have discovered that bone marrow-derived stem cells are present in the lungs of mice with pulmonary fibrosis. This finding suggests a new approach to treating the disease using stem cell therapy. Understanding how these stem cells engraft and interact with the lung tissue could lead to improved treatment outcomes.
Researchers at Yale University demonstrate that OspC is critical for Borrelia burgdorferi's ability to invade tick salivary glands and be transmitted to humans. Meanwhile, studies on hereditary spastic paraplegia and idiopathic pulmonary fibrosis reveal potential new targets for treatment.
Researchers developed a new composite score combining CT imaging and pulmonary function testing to assess treatment effects in young cystic fibrosis patients. A new test was also developed to predict increased mortality risk in idiopathic interstitial pneumonia patients with significant decline in pulmonary function.
A new Composite Physiologic Index (CPI) effectively tracks pulmonary fibrosis in patients and provides a more accurate prognostic indicator for interstitial pneumonia. Additionally, researchers explore the potential of stem cells to treat acute lung injury and its severe form, ARDS.
A randomized controlled trial found that sildenafil reduced pulmonary blood resistance, a key indicator of pulmonary hypertension. The study suggests sildenafil could be a promising candidate for long-term treatment of secondary pulmonary hypertension in lung fibrosis. Controlled trials are needed to confirm the findings.