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Other highlights in the March 6 issue of JNCI

Two new studies published in the Journal of the National Cancer Institute suggest that frequent tomato product consumption may reduce prostate cancer risk. Additionally, researchers found a possible role for the Ras gene in neuroblastoma regression and increased levels of GRP growth factor in head and neck cancers.

Photdynamic therapy: an effective treatment for head and neck cancers

A study of 114 patients with primary head and neck cancers found that photodynamic therapy achieved an overall response rate of 91% after two years, with 85% showing complete tumor elimination. The treatment also produced high one- and two-year overall survival rates of 90% and 81%, respectively.

Hopkins scientists link human papillomavirus (HPV) to head and neck cancer

Researchers found that human papillomavirus (HPV) is associated with a subset of head and neck cancers, particularly those of the oropharynx, which are more likely to be caused by HPV. The study also showed improved survival rates among patients with HPV-positive tumors compared to those with HPV-negative tumors.

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Genetic Alterations Linked To Cancer In Some Blood Samples

A recent study by Johns Hopkins Medicine detected genetic mutations specific to cancer in blood samples of six patients with head and neck cancer. The presence of DNA alterations in the blood was associated with large, advanced tumors and poor outcomes, including increased mortality rates.

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