Two new studies published in the Journal of the National Cancer Institute suggest that frequent tomato product consumption may reduce prostate cancer risk. Additionally, researchers found a possible role for the Ras gene in neuroblastoma regression and increased levels of GRP growth factor in head and neck cancers.
A study of 114 patients with primary head and neck cancers found that photodynamic therapy achieved an overall response rate of 91% after two years, with 85% showing complete tumor elimination. The treatment also produced high one- and two-year overall survival rates of 90% and 81%, respectively.
Researchers found that human papillomavirus (HPV) is associated with a subset of head and neck cancers, particularly those of the oropharynx, which are more likely to be caused by HPV. The study also showed improved survival rates among patients with HPV-positive tumors compared to those with HPV-negative tumors.
Scientists at Johns Hopkins have developed a novel approach for detecting cancer based on genetic mutations in mitochondrial DNA. The new test uses bodily fluids such as urine, saliva, and sputum to identify cancer-specific mutations.
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A new study by Duke University Medical Center found that a combination of intensive, twice-daily radiation therapy and simultaneous chemotherapy can control cancer more frequently. The treatment resulted in a significant improvement in disease control and patient survival rates.
In a Phase II study combining ONYX-015 with standard chemotherapy, nine out of ten patients experienced tumor regressions greater than 50 percent, including two complete responses. Thirty percent of patients treated with ONYX-015 alone showed significant tumor regression.
Researchers demonstrate intratumoral delivery of the E1A gene, downregulating HER-2/neu expression and tumor responses. The study shows promise for using E1A gene therapy to treat a broad range of cancers.
Researchers found that genetic variations in enzymes metabolizing drugs contribute to cancer risk, particularly head and neck cancer. Individuals with certain enzyme genotypes or histories of environmental exposures are at increased risk for cancer.
A recent study by Johns Hopkins Medicine detected genetic mutations specific to cancer in blood samples of six patients with head and neck cancer. The presence of DNA alterations in the blood was associated with large, advanced tumors and poor outcomes, including increased mortality rates.
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