Articles tagged with Heart Disease
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Researchers at Adelaide University have uncovered a crucial new mechanism controlling heart development by regulating key growth signals. Neural crest cells fine-tune Wnt signalling to ensure proper heart formation, and disruptions lead to serious congenital heart defects.
Researchers found that patients seen by cardiologists had lower mortality rates and fewer serious heart problems, including heart attack, sudden failure, or irregular heartbeat. The study suggests close teamwork between surgical and heart teams can improve outcomes after major surgery.
Middle-aged and older adults who were more active in the evenings had poorer cardiovascular health compared to their peers who were more active during the day. This study, published in the Journal of the American Heart Association, found that evening chronotypes are associated with behaviors that can affect cardiovascular health, such ...
A recent study from Penn State College of Medicine researchers found that helper T cells, typically involved in fighting infections, become overly activated in failing human hearts, causing damage. The activation of these T cells highlights the impact of inflammation and immune dysfunction in heart failure.
Researchers found structural and functional differences between mitral annular calcification and rheumatic mitral stenosis, which may lead to inaccurate diagnoses and treatment. The study suggests using disease-specific diagnostic criteria and management guidelines for patients with MAC-related stenosis.
A new study using satellite data confirms that California's shift to electric vehicles is making measurable differences in air quality and public health. For every 200 ZEVs added, nitrogen dioxide levels dropped 1.1%.
A multi-institutional study found that living in urban areas with visible trees is associated with a lower incidence of cardiovascular disease, with a 4% decrease. In contrast, higher percentages of visible grass were linked to a 6% increase in cardiovascular diseases.
Researchers identify circulating extracellular vesicles produced in diseased kidneys as the culprit behind toxicity in the heart. The discovery could lead to the development of a blood test to identify patients at high risk for serious heart problems and novel treatments to prevent and treat heart failure.
Researchers have shown that human hearts can regrow muscle cells after a heart attack, paving the way for new treatments to reverse heart failure. The discovery was made possible by pioneering techniques that use living tissue samples taken from patients during bypass surgery.
Researchers developed a highly sensitive blood test that can detect initial thrombin generation, a key trigger in blood clot formation. The test distinguishes between pathway-specific clotting abnormalities and suggests personalized treatment strategies, potentially predicting clinical outcomes.
An 18-week study found that maintaining grip strength and chair-rise performance alongside weight loss was possible without a prescribed strength-training program, alongside improvements in biomarkers linked to metabolic and cognitive aging. A plant-forward diet featuring fresh lean pork supported healthy-aging markers in older adults.
A Korea University study successfully mimics heart mechanics in organoids using three-dimensional magnetic torque, enhancing cardiac differentiation, maturation, and vascularization. This breakthrough could improve drug safety testing by providing more accurate human-relevant models for cardiotoxicity screening.
A new study found that choosing ARB drugs from the start can lead to better adherence and improved cardiovascular health. The study, which analyzed data from 340,000 patients, showed that ARB treatment resulted in fewer side effects and higher persistence rates compared to other drug classes.
A large study found that women who underwent bypass surgery had a lower risk of major cardiovascular events and mortality compared to those who received stenting. However, women who underwent stenting had a slightly lower stroke risk.
A new study by Mass General Brigham researchers found that patients with depression are at higher risk of cardiovascular disease due to stress-related brain activity, nervous system dysregulation, and chronic inflammation. The study also suggests that addressing chronic stress, anxiety, or depression is crucial for heart health.
A new study published in the Canadian Journal of Cardiology suggests that strong and supportive relationships can improve heart health for individuals with cardiovascular disease. The review highlights the need to include intimate partners in cardiac rehabilitation programs to support long-term heart health and quality of life.
New research from the American Heart Association finds a strong association between gum disease and increased risk of heart attack, stroke, atrial fibrillation, heart failure, and cardiometabolic health conditions. The study suggests that effective prevention and treatment of gum disease could potentially decrease the burden of cardiov...
Researchers developed an AI model that can detect coronary microvascular dysfunction using a common electrocardiogram, outperforming previous models in diagnostic tasks. The model can accurately identify a condition often missed in emergency department visits, providing a cost-effective and non-invasive way to diagnose serious heart co...
A $25M study will enroll 18,000 adults at high risk of heart disease and track their progress using smartphone fitness trackers. The trial aims to prove that increasing physical activity can prevent heart attacks and strokes.
Researchers have discovered a small RNA molecule that plays a key role in controlling cholesterol production and the development of heart disease. The molecule, tsRNA-Glu-CTC, was found to boost SREBP2 activity, leading to higher cholesterol levels and increased risk of atherosclerosis.
Researchers identified a way to suppress daily fluctuations in immune cells' activity, which may prevent tissue damage during daylight hours. A drug that targets neutrophils was found to alleviate inflammation and protect against infections.
A new study found that calcium accumulation in breast arteries and its progression on mammograms can predict future cardiovascular disease. Women with more severe calcification and those whose calcification worsened over time had a higher risk of heart-related events, such as heart attack, stroke, and death.
A new study published in the Journal of the American Heart Association has found that women with uterine fibroids are at an elevated risk of heart disease. The research, which analyzed data from over 450,000 women, suggests that fibroids may serve as a marker for identifying women at increased cardiovascular risk.
A new study from the University of Gothenburg has found that high teenage BMI and poor physical fitness are associated with a higher risk of developing severe bacterial infections in adulthood. The study, which followed over 44,000 men for three decades, shows that even at high normal weight, individuals are already at increased risk.
Researchers at Penn State are developing a small, durable ventricular assist device (VAD) specifically designed for young children with heart failure. The PSU Child VAD aims to provide long-term support while waiting for a heart transplant, improving quality of life and outcomes.
A new study published in JAMA Pediatrics suggests that early normalization of weight can protect the heart from childhood overweight. Researchers found that individuals who had normal weight in young adulthood after being overweight as children had a lower risk of heart attack compared to those who remained overweight.
In-flight cardiac arrest is a rare yet catastrophic event that claims up to 86% of air fatalities. Implementing automated external defibrillators (AEDs) on board could significantly boost survival rates from 6% to up to 70%. The authors recommend standardized CPR protocols training, telemedicine integration, and mandatory AED placement.
A recent study published in the American Journal of Preventive Cardiology found that only 13% of US adults with cardiovascular disease met optimal LDL-C management, highlighting significant gaps between guideline recommendations and clinical care. The study suggests actionable steps to improve adherence, including increased use of non-...
A large study found that people with type 1 and type 2 diabetes have a higher risk of sudden cardiac death, particularly in younger adults. The research also showed that sudden cardiac death contributes to shorter life expectancy for those with diabetes.
A study found that individuals with childhood overweight had a similar risk of coronary heart disease as those with normal weight throughout childhood and young adulthood. This has significant implications for public health planning, emphasizing early detection and treatment of childhood obesity.
A new 10-minute PET-CT scan reveals overactivity in adrenal glands, allowing for precise targeting of treatment. The test has huge potential to completely change the way high blood pressure is diagnosed and treated.
A recent study published in BMC Medicine found that people who consume polyphenol-rich foods and drinks, such as tea, coffee, and berries, may have lower predicted cardiovascular disease (CVD) risk. Higher adherence to polyphenol-rich dietary patterns was associated with healthier blood pressure and cholesterol profiles.
This study found a high in-hospital mortality rate of 7.24% among Indian patients undergoing heart valve replacements, with older and female patients facing higher risks. The results suggest that delayed surgeries may contribute to elevated mortality rates in this population.
Researchers have identified a distinct type of frailty in younger people driven by cardiovascular and metabolic illnesses, leading to poor outcomes and premature death. The study calls for routine frailty assessments in all heart attack patients, regardless of age.
A recent USF study found that smoking cannabis and consuming omega-6 enriched processed foods compromises the immune system, leading to weakened heart function and increased inflammation. The combination can weaken the body's defense mechanism, making it harder for the heart to repair damage caused by inhaling cannabis.
A mouse study by University of California, Riverside scientists suggests microplastic exposure may accelerate the development of atherosclerosis in males. The study found microplastics dramatically worsened plaque buildup in male mice, but not females.
Researchers found that eating a Mediterranean diet with moderate portions of lean beef did not increase blood levels of trimethylamine N-oxide (TMAO), an emerging indicator of cardiovascular disease risk. This suggests that dietary quality is more important than the amount of beef eaten in relation to heart health.
Dental teams can identify hypertension and cardiovascular disease risk through blood pressure screenings in routine care visits. The American Heart Association's Healthy Smiles, Healthy Hearts initiative provides standard blood pressure screening and referral guides, empowering dentists to connect patients with primary care.
Researchers found that a plant-based diet prevented the development of coronary microvascular dysfunction (CMD) and reversed established CMD in hypertensive rats. The diet improved function of blood vessel cells, counteracting the damaging effects of hypertension.
A Cochrane review found that low-dose colchicine reduced heart attacks and strokes in people with a history of heart disease or stroke. The study involved nearly 23,000 participants and showed that taking colchicine could prevent about two of each heart attack and stroke among those with cardiovascular disease.
A new genetic risk score combines rare and common gene variants with non-coding genome information to predict arrhythmia risk. This comprehensive framework can be applied to other genetically influenced diseases like cancer and Parkinson's Disease.
A recent study found that adults with heart disease who took vitamin D doses tailored to their individual needs reduced their risk of another heart attack by more than half. The study also showed that supplementation appeared beneficial for preventing heart attack specifically.
Sanjay Rajagopalan, a leading expert in cardiovascular medicine, has been recognized for his pioneering work on the impact of environmental risk factors on heart health. His research has informed public health policies worldwide and led to new understanding of how air pollution affects cardiovascular health.
A new study found that adding a PCSK9 inhibitor to a high-intensity cholesterol-lowering regimen reduced the risk of a first major cardiovascular event among adults with ASCVD or diabetes. The study suggests long-term lowering with PCSK9 inhibitors can improve cardiovascular morbidity and mortality over time.
A new study found that a polypill combining medications for heart failure improved heart function, symptoms, and quality of life. Adults with reduced ejection fraction heart failure who took the combined medication had fewer hospitalizations and greater medication adherence than those taking individual pills.
A new study found that providing healthy, medically tailored meals and fresh produce boxes along with nutrition counseling can improve the quality of life for people with heart failure. The 90-day trial showed significant benefits compared to dietary counseling without food delivery.
Using stress cardiac MRI testing to measure blood flow around the heart appears to improve diagnosis and patient quality of life for people with suspected angina. The test can help identify small vessel problems that may be causing chest pain, which are often under-recognized in women and other groups.
A study of 40,000 patients found that those with no coronary artery calcium have lower risk of death from all causes, including non-cardiac medical conditions. Patients with any level of CAC are 2-3 times more likely to die than those without CAC.
The American College of Cardiology and OpenEvidence are collaborating to integrate AI technology into clinical workflows, enhancing patient care and outcomes. The partnership aims to translate scientific discovery into clinical implementation, providing clinicians with timely and accurate medical evidence.
A new study reveals that a large gap between two common kidney function tests may indicate future disease, particularly among older adults. The research found that over a third of hospitalized participants had a significant difference in their creatinine and cystatin C readings, which can predict serious health problems.
A new study estimates that about 14% of adults worldwide have chronic kidney disease, with 1.5 million deaths in 2023. Early detection and treatment are crucial to prevent severe interventions like dialysis and transplantation.
A recent study found that fewer than half of young adults with severely high cholesterol levels start taking a statin within five years of first high LDL-C measurement. The study highlights significant care gaps in lipid management among adults aged 18-39, particularly those at high risk for premature atherosclerotic cardiovascular dis...
Researchers identified 15 bacterial species linked to CAD, including strains of friendly bacteria that can turn harmful. The study suggests that microbes play a critical role in the development and progression of CAD through inflammation, metabolic imbalance, and other pathways.
A study published in the Chinese Medical Journal identified GSTP1 as a key regulator that blocks JNK-driven ferroptosis, providing protection against DOX-induced cardiomyopathy. Overexpression of GSTP1 inhibited ferroptosis and improved DOX-induced heart injury.
The American Heart Association has named five finalists in its Health Tech Competition to present innovative solutions for cardiovascular conditions. The selected companies will showcase their technologies during the 2025 Scientific Sessions, where a panel of expert judges will evaluate their presentations.
Researchers developed an AI algorithm that accurately diagnosed multiple structural heart diseases from single-lead ECG sensors on smartwatches. The algorithm was trained on over 266,000 12-lead ECG recordings and prospectively validated in a real-world setting.
A preliminary study found that low-dose aspirin use was associated with a lower risk of major cardiovascular events, including heart attacks and strokes, among adults with Type 2 diabetes. The analysis of 11,500 individuals over 10 years showed that consistent aspirin use led to significant reductions in cardiovascular event rates.
A study found a nearly linear relationship between nighttime light exposure and an increased risk of heart disease. The research suggests that reducing exposure to excessive artificial light at night can counteract the effects and may be a public health concern.
Researchers found that combining three biomarkers – lipoprotein(a), remnant cholesterol, and high-sensitivity C-reactive protein – can reveal a nearly three-fold increase in heart attack risk. This combination approach may aid health care professionals in identifying individuals with high-risk profiles earlier.
Cardiac rehabilitation significantly improves short and long-term recovery for heart surgery patients, but women participate less than men due to barriers such as lower referral rates, clinician bias, and caregiving responsibilities. The American Heart Association scientific statement calls for targeted interventions to improve enrollm...