About The Study: In patients with symptomatic rheumatic heart disease, digoxin reduced the risk of a composite of all-cause death or new-onset or worsening heart failure, with little risk of toxicity. This study is being published to coincide with the European Society of Cardiology Heart Failure 2026 Congress.
Corresponding Author: To contact the corresponding author, Ganesan Karthikeyan, MD, DM, MSc, email karthik2010@gmail.com .
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(doi:10.1001/jama.2026.7335)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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