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Children’s Hospital of Philadelphia researchers identify key genetic differences between pediatric and adult forms of immune-mediated inflammatory diseases

Researchers from Children's Hospital of Philadelphia have found distinct genetic architecture in pediatric-onset rheumatic and inflammatory diseases compared to adults. The study identified 39 genome-wide significant variants associated with immune responses, including previously unreported variants.

SourceChildren's Hospital of Philadelphia·JournalAnnals of the Rheumatic Diseases·TypeExperimental study·DateAug 12, 2026
SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

Exploring idiopathic inflammatory myopathies

A population-based cohort study found that IIM subtypes differ in incidence, particularly by sex and ethnicity. Automated quantitative nailfold videocapillaroscopy (NVC) model shows superior discriminative capacity for predicting disease activity compared to traditional serum biomarkers.

SourceEuropean Alliance of Associations for Rheumatology (EULAR)·DateJun 5, 2026

The power of patient organization

A multidisciplinary patient organisation provides accessible, person-centred support through professional counselling, offering a non-clinical setting to discuss everyday challenges and work-related issues. The service also offers unique insights into unmet needs, such as medication shortages and administrative barriers.

SourceEuropean Alliance of Associations for Rheumatology (EULAR)·DateJun 5, 2026

Modern imaging with AI

New AI algorithms demonstrate improved accuracy in evaluating radiographic data and assessing joint inflammation. These innovations include the RADAR algorithm, ADMIRA, and thermography-based systems, offering promising alternatives to traditional imaging methods.

SourceEuropean Alliance of Associations for Rheumatology (EULAR)·DateJun 5, 2026
Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Patient education, support, and access to care

A new approach to managing fatigue in inflammatory arthritis combines physical activity and cognitive behavioral techniques. Digital patient education is shown to be cost-effective and efficient in improving patient outcomes. Caregiver-focused interventions are also crucial in supporting daily functioning and disease management.

SourceEuropean Alliance of Associations for Rheumatology (EULAR)·DateJun 5, 2026

Novel approaches to improve outcomes in PsA

Researchers present findings on a novel therapeutic strategy for PsA, using synovial biopsy-driven treatment with biologics targeting IL-17/23 axis. A separate study evaluates the effectiveness of personalized dietary interventions in improving clinical outcomes.

SourceEuropean Alliance of Associations for Rheumatology (EULAR)·DateJun 5, 2026

New: Classification criteria and recommendations in SpA

The updated ASAS-SPARTAN revised classification criteria for axSpA prioritize MRI of the sacroiliac joints and incorporate a focused set of clinical variables. The new recommendations also emphasize the role of imaging in diagnosing and managing both axial and peripheral SpA.

SourceEuropean Alliance of Associations for Rheumatology (EULAR)·DateJun 5, 2026

Improving understanding in SSc

A new study presented at EULAR 2026 highlights the importance of structured cardiac evaluation in systemic sclerosis, particularly for patients with multi-system disease. The research also identified PDE4B as a promising therapeutic target across various tissues and cell subsets, offering potential benefits for patients with early dise...

SourceEuropean Alliance of Associations for Rheumatology (EULAR)·DateJun 5, 2026
Rigol DP832 Triple-Output Bench Power Supply

Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.

Vasculitis updates: Glucorticoid use in AAV and GCA

A new study suggests that adding low-dose glucocorticoids to maintenance treatment for ANCA-associated vasculitis (AAV) does not reduce the risk of major flares, but is associated with an increased risk of chronic damage and hospitalization. In contrast, rituximab use was linked to a lower risk of major flares.

SourceEuropean Alliance of Associations for Rheumatology (EULAR)·DateJun 4, 2026

Outcome measures and the importance of (early) disease activity monitoring in SSc

A new study using the EUSTAR database found that patients with active disease at baseline had higher cumulative incidence rates of organ and multi-system involvement. Early disease activity monitoring is crucial for identifying patients at risk, guiding treatment decisions, and improving patient outcomes.

SourceEuropean Alliance of Associations for Rheumatology (EULAR)·DateJun 4, 2026

Updates in SLE and APS

Researchers have developed operational definitions of srSLE based on disease activity and treatment exposure, showing strong predictive performance. A novel autoantibody signature has also been identified to predict atherosclerosis progression in juvenile-onset systemic lupus erythematosus

SourceEuropean Alliance of Associations for Rheumatology (EULAR)·DateJun 4, 2026

Understanding comorbidities in RMD

Comorbidities such as cardiovascular disease, cognitive impairment, and osteoporotic fractures are common in RMD patients. Systemic autoimmune diseases increase the risk of cardiac arrhythmias and mortality. PPI use is linked to a higher risk of major osteoporotic fractures, while JAKi therapy may pose a risk of venous thromboembolism.

SourceEuropean Alliance of Associations for Rheumatology (EULAR)·DateJun 4, 2026

Digital platforms and AI

The study evaluated digital platforms and AI chatbots for improving health literacy in patients with RMDs. The results showed high usability, perceived usefulness, and trust among participants, suggesting a promising approach to patient education.

SourceEuropean Alliance of Associations for Rheumatology (EULAR)·DateJun 4, 2026
Nikon Monarch 5 8x42 Binoculars

Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.

Real-world evidence in rheumatology

Research studies reveal suboptimal adherence to treat-to-target strategies in rheumatoid arthritis, with lower rates among spondyloarthritis patients. Additionally, data from registries show the potential benefits of glucagon-like peptide-1 receptor agonists for weight loss and disease activity management in RMD.

SourceEuropean Alliance of Associations for Rheumatology (EULAR)·DateJun 3, 2026

CAR-T cell therapies in refractory RMD

Researchers present results from Phase 1 trials of CAR-T cell therapies in patients with refractory rheumatoid arthritis and systemic sclerosis, showing improved disease activity and clinical remission. The findings suggest an immunological 'reset' strategy may offer true curative potential for these severe diseases.

SourceEuropean Alliance of Associations for Rheumatology (EULAR)·DateJun 3, 2026

New insights in gout clinical management

A study found that patients continuing ULT remained flare-free for longer over 24 months, with a cumulative flare incidence of 12.3% compared to 31.8% in the ULT discontinuation attempt group. Effective weight management and exercise are key to managing gout and rheumatoid arthritis.

SourceEuropean Alliance of Associations for Rheumatology (EULAR)·DateJun 3, 2026

Severe asthma patients often battle multiple health conditions, study finds

A major new study has found that severe asthma patients are often battling other health conditions, with nearly all suffering from at least one major issue. The study identified three distinct profiles linked to how well asthma is controlled and the treatments needed, offering potential breakthroughs for improving care.

SourceUniversity of Southampton·JournalThe Lancet·TypeMeta-analysis·DateMay 19, 2026
Creality K1 Max 3D Printer

Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.

Ultrasound has potential to alter how the brain responds to pain

A new study suggests that ultrasound stimulation can bring about functionally meaningful changes in pain perception and brain connectivity. The research found a delayed analgesic effect, with participants reporting reduced pain intensity after 28-55 minutes following TUS application.

SourceUniversity of Plymouth·JournalNature Communications·TypeExperimental study·DateMay 13, 2026

Digoxin in patients with symptomatic rheumatic heart disease

In patients with symptomatic rheumatic heart disease, digoxin significantly reduced the risk of a composite of all-cause death or new-onset or worsening heart failure. The treatment had little risk of toxicity, making it a promising therapeutic option for these patients.

SourceJAMA Network·JournalJAMA·DateMay 10, 2026

2025 update for Behçet’s syndrome

The EULAR recommends a multidisciplinary approach to managing Behçet's syndrome, aiming to prevent irreversible organ damage and maximize quality of life. The updated guidelines prioritize monoclonal TNFi for patients with eye, vascular, or nervous system involvement, promoting earlier recognition and more consistent care.

SourceEuropean Alliance of Associations for Rheumatology (EULAR)·DateMar 23, 2026
Apple iPad Pro 11-inch (M4)

Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.

New: Points to Consider in AOSD

The European Alliance of Associations for Rheumatology (EULAR) has introduced three overarching principles and 11 points to consider for assessing disease activity in AOSD. The guidelines emphasize the importance of adopting a valid, reliable, and easily transferable definition of disease activity, which includes fever, skin rash, arth...

SourceEuropean Alliance of Associations for Rheumatology (EULAR)·JournalEULAR Rheumatology Open·DateDec 11, 2025

New disease activity score for APS

The European Alliance of Associations for Rheumatology has developed a new disease activity score (EAPSDAS) to assess clinical manifestations in antiphospholipid syndrome (APS). The score evaluates thrombotic, obstetric, microvascular, and non-thrombotic symptoms, providing insights into disease activity and treatment response.

SourceEuropean Alliance of Associations for Rheumatology (EULAR)·DateNov 19, 2025
Aranet4 Home CO2 Monitor

Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.

New antibodies developed that can inhibit inflammation in autoimmune diseases

Two first-in-class antibodies, C01 and C04, have been developed to inhibit inflammation in autoimmune diseases by blocking the high-affinity IgG receptor FcγRI. The antibodies were discovered using a unique immunization method and exhibit higher affinity for FcγRI than human IgG.

SourceUniversity Medical Center Utrecht·JournalNature Communications·TypeExperimental study·DateNov 19, 2025

Global experts outline path to long-term remission and cure in gout

A new review provides simplified criteria for defining gout remission and proposes integrated management strategies for sustained disease control. The authors highlight the importance of individualized urate-lowering therapy and proactive flare prevention, using imaging to show patients visual proof of crystal dissolution.

SourceChinese Medical Journals Publishing House Co., Ltd.·JournalRheumatology & Autoimmunity·TypeLiterature review·DateNov 13, 2025
Davis Instruments Vantage Pro2 Weather Station

Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.

New: Classification criteria for haemochromatosis arthropathy

Researchers developed a points-based classification model using eight variables to assess joint pain, genetic mutations, and iron loading. The criteria show promise in diagnosing haemochromatosis arthropathy with high specificity and sensitivity, paving the way for new treatment options.

SourceEuropean Alliance of Associations for Rheumatology (EULAR)·JournalAnnals of the Rheumatic Diseases·DateNov 5, 2025

Press registration now open for the EULAR 2026 Congress in London

The European Alliance of Associations for Rheumatology (EULAR) is hosting the EULAR 2026 Congress in London, featuring a scientific program with new clinical data and updated treatment guidelines. The congress will also provide exclusive media opportunities, including a press conference and one-on-one interviews with expert panelists.

SourceEuropean Alliance of Associations for Rheumatology (EULAR)·DateNov 3, 2025

New points to consider in psoriatic arthritis

EULAR has established new points to consider and consensus definitions for managing difficult-to-treat psoriatic arthritis, aiming to improve treatment options and care for patients. The guidelines focus on identifying the biology behind treatment non-response and promote personalized treatment approaches.

SourceEuropean Alliance of Associations for Rheumatology (EULAR)·DateOct 30, 2025

Gene linked to rheumatic disease controls cell movement

A recent study from Karolinska Institutet reveals how a gene associated with several rheumatic diseases affects cell movement. The researchers discovered that the DIORA1 gene regulates cell movement by interacting with MRCK kinases, which are important for the cell's skeleton and ability to move.

SourceKarolinska Institutet·JournalProceedings of the National Academy of Sciences·DateSep 29, 2025
Kestrel 3000 Pocket Weather Meter

Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.

Making an impact

The European Alliance of Associations for Rheumatology (EULAR) journal Annals of the Rheumatic Diseases (ARD) has achieved a notable increase in its impact factor to 20.6, surpassing 58 other titles in rheumatology and reaffirming its status as the leading journal for original research in both basic and clinical fields. This recognitio...

SourceEuropean Alliance of Associations for Rheumatology (EULAR)·DateJun 26, 2025

Zoster vaccine for people with inflammatory RMD

The recombinant zoster vaccine was found to be well-tolerated in patients with inflammatory rheumatic musculoskeletal diseases, with only a few reports of flare and serious AEs. The majority of patients tolerated the vaccine without significant adverse events.

SourceEuropean Alliance of Associations for Rheumatology (EULAR)·DateJun 11, 2025

Psoriatic arthritis: Hit hard and early

Recent studies suggest that early biologics in severe psoriatic arthritis may not significantly benefit patients compared to standard step-up care with methotrexate. However, a study found that intensive therapy with early biologics or combination csDMARDs can rapidly control disease activity and maintain better outcomes at 1 year.

SourceEuropean Alliance of Associations for Rheumatology (EULAR)·DateJun 11, 2025

Malfunctions in mitochondria influence skeletal ageing

Research discovers mitochondrial respiration impairment accelerates skeletal ageing by altering cell metabolism and reducing regenerative abilities. The study highlights the role of mitochondria in skeletal health and potential therapeutic avenues.

SourceUniversity of Cologne·JournalScience Advances·TypeExperimental study·DateApr 24, 2025
CalDigit TS4 Thunderbolt 4 Dock

CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.

Infertility linked to onset of systemic autoimmune rheumatic disease after childbirth

Women with infertility are at higher risk of developing SARD, including lupus and Sjögren's syndrome, even after accounting for pre-eclampsia and other pregnancy complications. Infertility treatments do not appear to increase this risk, suggesting that women may be undiagnosed or untreated.

SourceEuropean Society of Human Reproduction and Embryology·JournalHuman Reproduction·TypeObservational study·DateDec 4, 2024

Inflammatory myopathies and autoimmune gluten-related disorders

A scoping review found associations between myositis disease activity and gluten exposure in patients with inflammatory myopathies and celiac disease. The study suggests that gluten may act as an exogenous antigen driving myositis in genetically predisposed patients.

SourceBentham Science Publishers·JournalRecent Advances in Inflammation & Allergy Drug Discovery·DateDec 3, 2024
Celestron NexStar 8SE Computerized Telescope

Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.

Altered blood markers detected in individuals with periodontitis

Researchers at Umeå University have identified unique inflammatory protein profiles in the blood of individuals with severe periodontitis, which is associated with lower levels of EGF and OLR-1 proteins. The study provides a promising lead for developing biomarkers and treatments for the disease.

SourceUmea University·JournalJournal of Dental Research·TypeObservational study·DateSep 6, 2024

Synthetic plugs offer alternative to total knee replacements

Dr. Melissa Grunlan's team creates regenerative osteochondral plugs, a potential off-the-shelf device to treat OCDs and avoid total knee replacement surgery. The technology offers an alternative to autografting or total knee replacement, providing immediate support for joint function and potentially reducing post-operative complications.

SourceTexas A&M University·DateMay 31, 2024

Rheumatism: Taking cortisone with antacids can diminish bone density

A Charité study found that taking proton pump inhibitors (PPIs) simultaneously with cortisone preparations is associated with a higher risk of osteoporosis in patients with inflammatory rheumatic conditions. The study analyzed the bone health of over 1,500 patients and found that PPI use led to significantly lower bone density.

SourceCharité - Universitätsmedizin Berlin·JournalMayo Clinic Proceedings·TypeObservational study·DateMay 16, 2024

Professor Leith Zakraoui is awarded the 2024 IOF CNS Medal

Professor Leith Zakraoui was awarded the 2024 IOF CNS Medal for his dedicated work in advancing musculoskeletal health at both national and international levels. He has been a key figure in strengthening IOF activities in Africa and promoting education and awareness within the region.

SourceInternational Osteoporosis Foundation·DateApr 15, 2024
Apple MacBook Pro 14-inch (M4 Pro)

Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.

Treating gum disease after heart rhythm ablation reduced risk of AFib recurrence

A new study published in the Journal of the American Heart Association suggests that treating gum disease after a heart rhythm ablation procedure can lower oral inflammation and reduce the risk of AFib recurrence. Researchers found that an index measuring the severity of gum inflammation was associated with the return of AFib, highligh...

SourceAmerican Heart Association·JournalJournal of the American Heart Association·DateApr 10, 2024

Rheumatic diseases associated with childbearing problems

Women with selected rheumatic diseases experience a higher prevalence of childlessness, while risks for pre-eclampsia, low birth weight, and preterm delivery are increased for many conditions. Men with rheumatic conditions also face a higher risk of childlessness, although the impact on fertility varies among different diseases.

SourceOxford University Press USA·JournalRheumatology·TypeObservational study·DateMar 20, 2024

New: Fatigue in inflammatory RMD

The European Alliance of Associations for Rheumatology (EULAR) has developed new recommendations for managing fatigue in people with inflammatory rheumatic and musculoskeletal diseases. The guidelines emphasize the importance of monitoring fatigue and offering management options based on a shared decision between patients and healthcar...

SourceEuropean Alliance of Associations for Rheumatology (EULAR)·JournalAnnals of the Rheumatic Diseases·DateDec 8, 2023
AmScope B120C-5M Compound Microscope

AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.

Updated: SLE management

The updated EULAR recommendations for managing SLE emphasize individualized, multidisciplinary care and consider patient education and societal costs. Non-pharmacological interventions and careful drug selection based on disease type and severity are also key to improving long-term outcomes.

SourceEuropean Alliance of Associations for Rheumatology (EULAR)·JournalAnnals of the Rheumatic Diseases·DateDec 8, 2023

Does stem cell transplantation benefit patients with knee osteoarthritis?

A systematic review and meta-analysis of 16 studies involving 875 patients with knee osteoarthritis found significant reductions in patient-reported pain from the third month onwards. Stem cell treatment was most effective when using patient's own fat-derived stem cells, leading to better pain alleviation and recovery of joint function.

SourceWiley·JournalJournal of Orthopaedic Research®·DateNov 22, 2023

Disturbances in sensory neurons may alter transient pain into chronic pain

A recent study found that transient inflammatory pain causes persistent mitochondrial and metabolic disturbances in sensory neurons, leading to failure in pain resolution. Targeting the cellular redox balance prevents and treats chronic inflammatory pain in rodents.

SourceUniversity Medical Center Utrecht·JournalCell Reports Medicine·TypeExperimental study·DateNov 8, 2023
Garmin GPSMAP 67i with inReach

Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.

BU researchers suggest new approach for testing treatments for osteoarthritis

Researchers propose a new approach to testing treatments for osteoarthritis by focusing on individuals who sustain knee trauma, such as ACL tears. This approach identifies a high-risk group of patients with early disease, allowing for targeted treatment and prevention strategies.

SourceBoston University School of Medicine·JournalAnnals of the Rheumatic Diseases·TypeData/statistical analysis·DateOct 12, 2023

Cell therapy can reduce risk of death from COVID-19 by 60%, study shows

A systematic review and meta-analysis of 195 clinical trials found that cell therapy can reduce the risk of death from COVID-19 by 60%. The studies, conducted in 30 countries between January 2020 and December 2021, used various types of cells, including mesenchymal stem cells and natural killer cells.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalFrontiers in Immunology·DateSep 18, 2023