Articles tagged with Heart Disease
A study published in European Heart Journal found that between 30-40% of obese patients are metabolically healthy, exhibiting better cardiorespiratory fitness and a lower mortality risk. Health professionals can use lipid profile, BMI, and fitness to assess the risk for heart or cancer disease in obese individuals.
A study published in JAMA found that obese individuals who underwent gastric bypass surgery experienced significant weight loss and reductions in cardiovascular risk factors. The surgery helped improve fitness, quality of life, and even reduced the incidence of diabetes, hypertension, and sleep apnea.
Duc Dong, Ph.D., receives NIH New Innovator Award to explore genetic reprogramming as a means to grow replacement organs. The technology aims to induce new tissue development in zebrafish, allowing for rapid screening of genes and chemicals important for efficient genetic reprogramming.
Huei-Sheng Vincent Chen, PhD, receives $1.58 million CIRM Basic Biology IV award to develop personalized models of inherited heart conditions using stem cells derived from patients' own skin cells. The goal is to develop new therapies for these diseases and better understand their causes.
The study found that women with heart disease can safely go through pregnancy if adequately evaluated, counseled, and receive high-quality care. However, developing countries have poorer outcomes due to limited access to better care, while cardiomyopathy patients face higher mortality rates.
Scientists at Virginia Tech and the University of Texas Southwestern Medical Center found that two mini-molecules called microRNAs can help stem the nation's obesity epidemic. The discovery suggests that treatments targeting these two specific microRNAs may help regulate cellular metabolism and increase energy expenditure, leading to r...
Researchers identified a genetic variant associated with elevated C-reactive protein levels in African American women, linked to higher risk of heart disease, diabetes, and some cancers. The study found that genetic factors specific to African Americans may contribute to the observed differences in inflammation levels.
Researchers propose that certain dietary fats encourage the growth of harmful bacteria, leading to low-level inflammation and chronic disease. Unsaturated fats, like omega-3 fatty acids, have strong antimicrobial properties, weakening bacterial cell membranes.
Researchers found that midlife fitness levels can lower the onset of chronic diseases such as congestive heart failure, Alzheimer's disease, and colon cancer decades later. Fitter individuals aged well with fewer chronic illnesses to impact their quality of life.
Researchers have discovered that archived Guthrie cards hold valuable epigenetic information about newborns, which can be used to predict future health outcomes. The study found that these marks are present at birth and remain stable into early childhood, offering a unique window into the development of diseases.
A recent study published in JAMA found that coronary artery calcium (CAC) scans are superior to other assessment tools in identifying individuals at intermediate risk of cardiovascular disease. The CAC scan uses a CT scan to detect calcium build-up in the arteries, allowing for more precise prediction of heart disease risk.
Scientists found a link between high galectin-3 levels and increased risk of cancer and heart disease. A new blood test can predict disease outcomes, while modified citrus pectin may block galectin-3's negative effects.
A new study found that people with blood types A, B, or AB have a higher risk of coronary heart disease compared to those with blood type O. The study's findings suggest that knowing one's blood type can help physicians better understand who is at risk for developing heart disease.
Researchers have identified CD4 T cells as the key players in an autoimmune response that fuels inflammation in the artery wall, leading to plaque buildup. A potential vaccine could target this response, offering a new approach to preventing heart disease.
A new study published in the Journal of Nutrition found that consuming grapes reduced blood pressure, improved blood flow and decreased inflammation in men with metabolic syndrome. The polyphenols found in grapes are thought to be responsible for these beneficial effects.
Researchers at Sanford-Burnham Medical Research Institute have discovered a molecule that converts stem cells into heart cells, potentially replacing diseased or damaged tissue in heart disease patients. The molecule, ITD-1, blocks TGFϐ signaling, allowing stem cells to differentiate into cardiomyocytes.
A recent study found that only 19% of seniors with lung disease quit smoking within two years, while regular exercise improved were rare. The research suggests intensive efforts are needed to help seniors make lifestyle changes after a chronic diagnosis.
A new study from Harvard School of Public Health found that men with prostate cancer are more likely to die from preventable conditions such as heart disease than the disease itself. The study emphasizes the importance of healthy lifestyle changes in prostate cancer management.
A $4.7 million study aims to investigate why people with diabetes suffer from unusually severe forms of heart disease. The researchers suspect that abnormal lipid metabolism is a key culprit, leading to inflammation and damage to heart cells.
Researchers at Brigham and Women's Hospital discovered that analyzing HDL particle count provides stronger cardio-protection than traditional HDL cholesterol measurement. The study suggests that raising HDL levels through other means may be more effective in preventing coronary heart disease.
A new study suggests adding a modified echo to current screenings to identify student athletes with heart problems that could lead to sudden death. The study found that an abbreviated echo can increase the sensitivity of finding heart defects in competitive athletes.
Researchers at the University of Warwick discovered that strawberry extracts positively activate the Nrf2 protein, decreasing blood lipids and cholesterol levels. This activation reduces the risk of developing heart disease and diabetes by counteracting post-meal blood glucose and low-density lipoprotein.
A prospective cohort study found associations between plasma concentrations of saturated phospholipid fatty acids and increased risk of coronary heart disease. In contrast, n-6 polyunsaturated phospholipid fatty acids showed an inverse association with coronary heart disease risk.
A landmark randomized clinical trial is testing whether earlier treatment can prevent or delay heart damage in people with Duchenne muscular dystrophy. The study uses enhanced cardiac magnetic resonance imaging to detect early changes in heart function and evaluate the effectiveness of an anti-fibrosis drug regimen.
Researchers at Tufts University have developed two surveys, FETCH and CATCH, to evaluate the quality of life for dogs and cats with heart disease. The tools ask owners to rank aspects of their pet's health on a scale of 0-5, allowing veterinarians to assess the animal's perceived quality of life.
Scientists have identified genetic heart conditions as a possible cause of unexplained stillbirths, with up to 8% of cases attributed to cardiac channelopathies. The research, led by Ms Alice Ghidoni, used molecular screening to detect disease-causing variants in stillborn fetuses.
A new study finds that patients with hyperthyroidism are at a greater risk of hospitalization for heart and blood-vessel disease, even years after successful thyroid surgery. The risk is largely due to the disease itself, rather than treatment, and persists for up to two decades.
A new survey found that only 36.5% of coronary heart disease patients in Europe participate in cardiac rehabilitation, despite the American Heart Association's recommendation. The study suggests that smoking, older age, and lower educational attainment are associated with lower attendance rates.
A large-scale Canadian study has found that patients with chronic kidney disease are at comparable risk of future coronary events to those who have previously suffered a heart attack. This could lead to targeted treatment for high-risk individuals, including the use of statins to reduce 'bad' fats in the bloodstream.
Researchers at the Salk Institute found that embryonic stem cells enter a unique, privileged state during early embryo development where specific genes are activated, allowing them to differentiate into any cell type. This discovery may provide insight into how to improve the clinical value of ES cells for therapy.
A new study from Children's National Medical Center found that routine echocardiogram screenings can identify three times as many cases of rheumatic heart disease (RHD) as clinical examinations. The screenings can detect clinically silent RHD in children, allowing for early intervention and prevention of serious complications.
A study found that while improved treatment uptake contributed significantly to reduced death rates from coronary heart disease, socioeconomic disparities persisted. The authors call for evidence-based policies to promote healthier diets and address social gradients in risk factors.
New research from the University of Copenhagen found that even slightly higher blood glucose levels increase the risk of ischemic heart disease. A study of over 80,000 participants revealed a 69% increase in risk with just 1 mmol above normal levels.
A Wayne State University School of Medicine study found that 90.7% of patients with hypertension also had hidden heart disease, emphasizing the need for early detection and treatment. The study's results have significant implications for preventing cardiovascular disease in high-risk populations.
Researchers used echocardiograms to spot early heart disease in rheumatoid arthritis patients. The study found that the condition is often underestimated by traditional risk assessment tools.
A Tel Aviv University researcher found that cardiac patients living in high-pollution areas were 43% more likely to have a second heart attack, and 46% more likely to suffer a stroke. Long-term exposure to air pollution was linked to increased risk of mortality and recurrent vascular events.
The study reveals that tafamidis works by stabilizing the transthyretin (TTR) protein tetramer, preventing it from aggregating into amyloids. This stabilization prevents nerve destruction in polyneuropathy patients and delays disease progression.
A new stem cell technique allows for efficient generation of abundant cardiomyocytes, critical heart muscle cells. This method is more efficient and robust than existing methods, promising a uniform alternative for research and pharmaceutical applications.
A study found that behavioral support from peers and primary care office staff can help patients with poor blood pressure control improve their blood pressure levels by as much as starting a new drug. The intervention reduced systolic pressure by 7.2mmHg in the treatment group compared to 0.8mmHg in the control group.
Obesity affects 62% of Canadian adults, with a significant economic burden and increased risk of related diseases. The 5A model provides an effective approach to counselling patients, combining assess/ask, advise, agree, assist, and arrange steps for successful weight loss and maintenance.
Researchers at Yale University found that short- and long-term mortality decreased in all subgroups of age, sex, and race after mitral valve surgery. Despite this improvement, female and non-white patients still experienced higher mortality rates compared to male and white patients.
Peripartum cardiomyopathy, a life-threatening heart condition, is revealed to be a vascular disease caused by an imbalance of angiogenic proteins in the heart. The study suggests that proangiogenic therapies may be beneficial treatments for this condition.
University of Guelph researchers found the location and effect of abnormal heart proteins that can cause cardiac failure. They discovered three variants affecting heart contractions and three others impacting stability and efficiency, paving the way for targeted therapies.
Researchers found two subclasses of HDL cholesterol: one with apolipoprotein C-III increases heart disease risk, while the other without it is protective. Measuring HDL-apoC-III may be a better gauge of heart disease risk than total HDL.
A study published at the University of Granada found that heart rehabilitation programs significantly improved cardiovascular health in patients with heart disease. The program reduced total cholesterol and plasma triglyceride levels, promoted healthier eating habits, and increased physical activity among participants.
Researchers at UC Irvine found that moderate to severe COPD patients with low heart disease risk had a significantly better prognosis. The study suggests addressing cardiac risk factors can improve outcomes in people with COPD, and highlights the importance of cardiovascular health for lung disease patients.
A Mendelian randomization analysis found a continuous association between increased BMI and risk for ischemic heart disease, with no threshold below which BMI increase has no effect on IHD risk. The study's findings have important implications for public health policy.
A new study challenges traditional risk factors for contrast-induced nephrotoxicity, finding that patients with history of renal disease, hypertension, and heart disease are at greater risk. In contrast, diabetes is not a significant predictor of reduced renal function.
New research published in PLOS Medicine reveals a strong link between body mass index (BMI) and ischemic heart disease (IHD) risk. A significant increase in BMI was found to elevate the risk of developing IHD by 50% on average, highlighting the importance of addressing obesity levels in reducing cardiovascular risk.
Researchers at A*STAR's Institute of Medical Biology found that reducing SUN1 levels in mouse models doubled the life spans of those with progeria and tripled it for those with Emery-Dreifuss muscular dystrophy. This discovery opens up a possibility for therapeutic use of reduced SUN1 levels for other forms of heart disease.
A recent study published in the Journal of Internal Medicine found that city center residents are almost twice as likely to develop coronary artery calcification as those living in less polluted urban and rural areas. The study also discovered that males, older participants, diabetics, and smokers face higher risks.
Scientists at the Salk Institute have identified fibroblast growth factor 1 (FGF1) as a crucial protein in maintaining insulin sensitivity and regulating fat storage. The discovery offers new avenues for treating type 2 diabetes, potentially providing a more natural alternative to existing antidiabetic drugs.
A new study at the World Congress of Cardiology found that women with diagnosed heart disease are more likely to give birth to female babies. The study, which reviewed 200 pregnant women with cardiac disease, found that 75% of their children were female.
A new report highlights significant gaps in public awareness regarding the cardiovascular risks of tobacco use and secondhand smoke. Half of all Chinese smokers and one-third of Indian and Vietnamese smokers are unaware that smoking causes heart disease, with even higher rates among non-smokers.
Patients with rheumatic heart disease in the Middle East are being admitted too late for surgery, highlighting the need for early screening and prevention programs. The World Heart Federation calls for coordinated efforts to prevent progression to severe RHD, which can be prevented with penicillin.
Researchers at the University of Cincinnati have found a cellular pathway linked to obesity-related disorders such as diabetes, heart disease, and fatty liver disease. Deleting the enzyme histone deacetylase 9 (HDAC9) completely protected mice against high-fat feeding's negative health consequences.
A new study has identified left-ventricular hyper-trabeculation as a common feature among black male athletes, with a prevalence of 6.8% compared to 0.4% in non-athletes. This finding raises concerns about the challenges of differentiating between athlete's heart and serious medical conditions in this demographic.
Research suggests that CD36 protein, involved in cellular inflammation, increases harmful effects of LDL cholesterol. Mice infected with gum disease bacteria showed increased fatty plaque accumulation, while those with deleted CD36 gene remained plaque-free.
Research from Duke University Medical Center finds that patients with voice problems experience nearly as many days of short-term disability claim and work productivity losses as those with chronic conditions. The study reveals that up to 40 lost workdays and $3,400 in short-term disability payments occur annually due to dysphonia.
Researchers found that EKG abnormalities in healthy elderly individuals increased the risk of heart attack. The study, which followed 2,192 adults aged 70 and older for eight years, suggests that EKGs could be used to detect heart disease earlier in patients without chest pain or symptoms.