Articles tagged with Heart Disease
Researchers found that blocking the action of a signaling protein in cardiac muscle cells halted serious ill effects of high blood pressure on the heart, including enlargement and scar tissue formation. Further tests revealed potential new treatments for heart failure by targeting specific proteins involved in disease progression.
Scientists have developed a new imaging agent using tantalum oxide nanoparticles, which stays in the body long enough to image multiple organs. The material is inexpensive and has shown promising results in laboratory tests, potentially overcoming limitations of existing imaging agents.
A study found that HIV infection is associated with an increased risk of heart failure, even after adjusting for traditional risk factors. Patients with high baseline HIV-1 RNA levels also showed a higher risk of heart failure.
A recent study examining dietary cholesterol, egg intake, and heart disease risk found that saturated fat may be a greater contributor to increased blood cholesterol than previously thought. The study also suggests that egg consumption does not significantly increase blood cholesterol levels, contrary to long-held assumptions.
Researchers found that drinking tart cherry juice daily can significantly reduce inflammation and cardiovascular risk in overweight adults. A cherry diet also reduced atherosclerosis and other heart disease risk factors in mice, with improved cardiovascular health leading to a 65% reduction in early death.
A 17-year study of 37,000 Israeli teenagers found that normal-range adolescent BMI can predict type 2 diabetes and heart disease risk in young adults. Elevated BMI at any age was associated with increased disease risk, especially at ages 17 and 30.
A large cohort study found that normal-range body mass index in adolescence significantly increases the risk of developing type 2 diabetes and coronary heart disease in young adulthood. Elevated BMI was associated with a 10% to 12% increased risk for these diseases.
A new study discovered that specific intestinal microflora metabolize phosphatidyl choline, a common dietary lipid found in animal products, into compounds associated with increased cardiovascular disease risk. The study found that higher levels of these compounds are linked to an increased risk of heart attack, stroke, and death.
The Lancet NCD Action Group and the NCD Alliance recommend five priority interventions: reducing tobacco use, lowering salt intake, improving diets, reducing hazardous alcohol intake, and increasing access to essential drugs. These actions aim to reduce NCD death rates by 2% per year, avoiding an estimated 36 million deaths over 10 years.
A study of nearly 600 patients found that anaemia was frequently found in patients with severe non-inflammatory respiratory diseases. The research team discovered that older patients, those with other health problems and poor nutrition were more likely to have anaemia.
Researchers at the University of Colorado School of Medicine found that people living at high altitudes have a lower chance of dying from ischemic heart disease and tend to live longer than others. Lower oxygen levels may spur genes to create blood vessels, reducing the risk of heart disease deaths.
Patients who have suffered a mini stroke are at twice the risk of heart attack compared to the general population. The study found that the risk of heart attack among TIA patients was about 1 percent per year, double that of people who had never had a TIA.
A study of Yup'ik Eskimos found that high intake of omega-3 fats from fish reduces markers of chronic disease risk in overweight/obese people. Obesity did not increase inflammation and blood triglycerides among participants with high blood levels of omega-3 fats.
Researchers found that only 1 in 4 studies reported on participant ethnicity, with most being superficial in scope. The study highlights the importance of considering ethnicity when conducting research on heart disease and stroke prevention to target prevention strategies effectively.
Researchers from Karolinska Institutet have discovered that specific inflammatory substances called leukotrienes play a crucial role in the development of aortic stenosis. The study found that anti-inflammatory medication may be a promising new treatment for the disease, which affects millions of people worldwide.
Researchers have discovered a molecule, Wnt1, that improves the function of endothelial progenitor cells, increasing blood flow to organs with previously blocked circulation. The finding could enhance clinical trials testing these powerful cells in patients hospitalized with cardiac arrest.
A new collaborative care program has been shown to significantly improve depression, anxiety, and emotional quality of life in heart disease patients. After six and twelve weeks, participants in the program reported improved symptoms and better adherence to healthy activities compared to those receiving usual care.
The Canadian government and Heart and Stroke Foundation have launched three new research initiatives to tackle obesity, focusing on neighbourhood design, physical activity, and access to healthy food options.
A large-scale study led by the University of Leicester has discovered 13 new genes that increase the risk of heart attacks. The research, known as CARDIoGRAM, involved over 140,000 participants and 167 clinicians from around the world.
A new University of Missouri study found that behavior-changing strategies like self-monitoring and goal-setting significantly increased physical activity levels among healthy adults. The research suggests focusing on practical strategies rather than trying to change attitudes or beliefs about exercise.
Patients with serious mental health conditions are at risk of poor physical health due to antipsychotic medication. The Lancet Editorial emphasizes the need for integrated care and training in cardiometabolic disease management. Effective interventions like smoking cessation and weight loss can improve patients' physical health.
Researchers have identified mutations in the MYH7 gene as a contributing factor to Ebstein's anomaly, a rare congenital valvular heart disease. The study found that these mutations can also be associated with left ventricular noncompaction, a condition that increases the risk of sudden cardiac death.
A new study suggests that abnormal heart rate turbulence may be a significant risk factor for heart disease death, even among those considered low-risk. Abnormal heart rate turbulence was found to be an even stronger predictor of heart disease death than elevated C-reactive protein levels in this population.
A new study by St. Michael's Hospital researchers found that Canadians living in high-risk neighborhoods are twice as likely to report poor health, particularly on the Atlantic and Pacific coasts. The study highlights the importance of targeted health policies for specific regions and neighborhoods at greatest risk.
Researchers at St. Michael's Hospital developed an online tool that estimates stroke patient mortality based on risk factors like heart disease, diabetes, and cancer. The tool was validated in a study of 12,262 patients and found to be accurate in predicting death rates 30 days and one year after ischemic stroke.
Researchers create microsponges that capture biomarkers, enabling rapid disease diagnosis with high accuracy. The technology has the potential to replace traditional diagnostic methods at a lower cost.
A multicenter study found that recalled Sprint Fidelis implantable cardioverter-defibrillator (ICD) leads failed at a higher rate in younger patients, women, and individuals with hereditary heart disease. However, the failure was not associated with death or serious injuries.
A study by Purdue University found that diabetes affects not only patients but also their spouses, causing similar distress and depressive symptoms. The research highlights the importance of considering the emotional impact on both individuals in diabetes care.
A recent study published in BMC Public Health found that wounded veterans are more likely to die from coronary heart disease due to war-time stress. The research, conducted by Dr. Seppo Nikkari and his team, surveyed 55-year-old Finnish WW2 veterans and found a significant correlation between physical trauma and an increased risk of CHD.
A cognitive behavioral therapy program focusing on stress management appears to decrease the risk of recurrent heart attacks and cardiovascular events in patients with heart disease. The study found that the program was associated with a 41% lower rate of fatal and non-fatal heart events, as well as fewer recurrent heart attacks.
A University of Manchester scientist has discovered the mechanism behind skin cells' tight binding, which could lead to new treatments for debilitating skin diseases and heart problems. The study found that glue molecules bind specifically to similar molecules on neighboring cells, creating a resilient structure.
Researchers at Sanford-Burnham Medical Research Institute have discovered a genetic mechanism that causes lipotoxic cardiomyopathy independently of a diet high in fat. The study found that an imbalance in cellular fats can lead to heart problems, and targeting the SREBP protein may help prevent these issues.
A European study found that consuming at least eight portions of fruit and vegetables daily reduces the risk of death from ischaemic heart disease by 22% compared to those who consume fewer than three portions. The study analyzed data from over 300,000 participants in eight European countries.
A new Cochrane Systematic Review questions the benefits of statins in people with no previous history of heart disease. Statin use should be prescribed with caution in those at low risk of cardiovascular disease, as the absolute numbers of people who benefit are lower.
A recent study tracked almost 1,900 people over 29 years to uncover the link between larger high-density lipoprotein particles and reduced risk of heart disease. The research found that an increase in HDL2 particles significantly lowered heart disease risk.
A randomized controlled trial found that a team-based primary care intervention called TEAMcare reduced depression and improved blood sugar control, blood pressure, and cholesterol levels in patients with diabetes and heart disease. Patients assigned to the TEAMcare intervention had better quality of life and were more likely to have t...
Adhering to UK dietary guidelines on fruit and vegetable consumption, fibre, fats, and salt could prevent or delay up to 33,000 deaths annually. Reducing these components' intake significantly impacts mortality rates.
A study published in the American Journal of Clinical Nutrition found no link between dairy consumption and increased risk of heart disease, stroke, or total mortality. The research also revealed that drinking three glasses of milk per day may lead to a reduced risk of cardiovascular disease.
A rapidly ageing population in the UK is leading to a surge in degenerative valvular heart disease cases, with over 13% of those aged 75 and above affected. Specialist VHD centres are needed to address the issue, with current treatment provision showing wide variation and inadequate follow-up care.
A French study found that men's smoking rates have decreased by 15% since the mid-1980s, resulting in a predicted decline of 10-15% in coronary heart disease deaths. In contrast, women's smoking rates have increased, leading to a predicted rise of up to 4.9% in heart disease mortality rates.
A recent study has found that high blood pressure is more common among black women in the southeastern US compared to white men. The researchers analyzed data from the Coronary Artery Risk Development in Young Adults (CARDIA) study and discovered significant geographic, racial, and gender differences in hypertension risk.
A recent study found that nearly half of youth with type 1 and type 2 diabetes are current smokers, increasing their risk for heart disease. Aggressive smoking prevention and cessation programs are needed to prevent or delay heart disease in this population.
Researchers discovered that exposure to high levels of air pollution narrows tiny blood vessels in the retina, increasing the risk of heart disease. Exposure to even small amounts of pollution can cause a 3% increase in heart disease risk for women living in polluted areas.
Researchers from Leicester and Cambridge discovered genetic markers that identify people at risk of developing potentially fatal blood clots. This breakthrough advances ways of detecting and treating coronary heart disease, a leading cause of premature death.
Scientists at the University of Strathclyde and Glasgow are using a £1 million grant to investigate the causes of serious diseases like heart disease, stroke, and high blood pressure.
Researchers at the University of Cincinnati found a potential genetic target, miR765, which can down-regulate protein phosphatase 1 inhibitor-1 and reduce cardiac muscle contractility. This micro-RNA may play a role in heart disease development by decreasing or deactivating proteins that help the heart function at full capacity.
Researchers discovered reusing explanted ICDs with sterilized batteries is safe for patients. Shorter sleep duration linked to carotid artery thickening in men, while rapid body cooling improves heart function after CPR. Intravenous iron treatment boosts quality of life and kidney function in some chronic heart failure patients.
A study found that early surgical procedures to open blocked arteries improved blood flow to the heart better than aggressive medical treatment alone. The research showed that revascularization reduced ischemia, a key factor in controlling symptoms.
Cardiac researchers at the University of Cincinnati found a new cellular pathway that could help develop therapeutic treatments for obesity-related disorders, including diabetes and heart disease. The study identified histone deacetylase 9 (HDAC9) as a potential target for intervention.
The Glavy Lab team identified the Werner Helicase Interacting Protein 1 (WHIP), a disease-related protein outside its known range, within nuclear pore complexes. WHIP may play an independent role in maintaining genome stability and detecting genetic damage, offering new avenues for understanding gene repair and expression.
Researchers identified irregular heartbeat in pacemaker recipients as a potential stroke risk factor. Meanwhile, disparities in cardiovascular care persist despite healthcare reform, with African-Americans and those with lower socioeconomic status receiving fewer invasive procedures. Stress tests using exercise electrocardiography and ...
Researchers found that individuals with poor sleep quality had higher levels of inflammatory markers, including C-reactive protein, even after adjusting for known risk factors. Chronic lack of sleep may contribute to cardiovascular mortality, but the exact mechanism remains uncertain.
Research found that women with high job strain have a 40% increased risk of cardiovascular disease, including heart attacks and the need for procedures to open blocked arteries. Job insecurity was also associated with risk factors for cardiovascular disease such as high blood pressure, increased cholesterol, and excess body weight.
A study by the University of Leicester found that undetected high blood pressure is associated with a higher risk of dying from coronary heart disease. The research reveals that areas with greater deprivation, more smokers, and more people with diabetes have a higher mortality rate from coronary heart disease.
A study in England found that coronary heart disease mortality rates vary greatly between local populations due to factors such as low socioeconomic status, white ethnicity, smoking levels, and diabetes. The study suggests that programs to reduce mortality should target population characteristics rather than healthcare services.
A recent study in fruit flies discovered a molecular connection between obesity and heart disease, with the protein TOR playing a key role. Researchers found that manipulating TOR protected the hearts of obese flies from damage caused by high-fat diets.
A landmark study found that a high resting heart rate is associated with a higher risk of death from cardiovascular and all causes, even after adjusting for other risk factors. Patients with heart rates above 78 beats per minute had a 39% increased risk of major vascular events.
Newfoundland researchers have cracked the genetic code of arrhythmogenic right ventricular cardiomyopathy (ARVC), a rare genetic condition causing sudden cardiac death. The team developed an implantable cardiodefibrillator program to prevent fatal arrhythmic events, significantly improving survival rates among high-risk individuals.
Researchers found that participation in cardiac rehab was associated with decreased risk of emergency room visits and hospitalization, as well as lower mortality rates. A new structured home-based cardiac rehab program may help overcome barriers to attendance, particularly for women and the elderly.
Research published in Heart found that men with low testosterone levels were more likely to die prematurely from heart disease and all causes. The study of 930 men with coronary artery heart disease showed that those with low testosterone had nearly twice the risk of death compared to those with normal levels.