Articles tagged with Pain
A team of researchers has solved a rare, debilitating disease by identifying a genetic mutation as its cause. The disease, Pyrin Associated Autoinflammation with Neutrphilic Dermatosis (PAAND), affects half of the children of patients who have the condition.
A study found that half of patients visiting their GP with dental problems were prescribed unnecessary antibiotics, despite these not providing a definitive treatment. This has raised concerns about the impact on long-term dental health and potential contributions to antibiotic resistance.
Researchers propose a new theory that pain is a complex interaction of multiple elements, including sensory processes and emotional responses. A study found that the brain processes both general and specific components of pain in parallel, allowing for efficient processing of unpleasant experiences.
Women experiencing suspected heart disease exhibit similar classic symptoms to men, including chest pain and shortness of breath, but differ in diagnosis and risk assessment. The study found that women have more risk factors for heart disease than men, yet are often assessed as lower risk.
TeamStudy, an iPhone research app built using ResearchKit, allows former NFL players and the public to engage in the study of athlete health. The app enables researchers to capture data from participants across the nation, providing insights into everyday experiences of former NFL players.
A recent study by University of Kent researchers refutes the use of traditional pain measurement methods in exercise experiments. They found that people who are ready to engage in greater amounts of pain perform better in exercise activities. The researchers suggest measuring EIP tolerance as a more accurate predictor of performance.
Sylentis presents positive Phase II results with SYL1001 for treating ocular discomfort, achieving primary and secondary endpoints in reducing ocular pain and conjunctival hyperaemia. The trials also confirm a favorable safety profile of SYL1001.
A study published in The Journal of Craniofacial Surgery found that ultrasonic piezosurgery equipment reduces trauma, pain, and swelling after genioplasty. Patients undergoing genioplasty using piezosurgery had lower pain scores and reduced swelling compared to traditional surgical drills.
Researchers at Duke University have identified a potential drug target in the skin for treating short-term itch. By targeting a specific ion channel protein called TRPV4, scientists hope to develop topical treatments that can suppress itch and inflammation.
A spider toxin analogue, PnPP-19, has shown promise in relieving pain by targeting nervous system receptors similar to opioids and cannabis. The compound is also being studied for erectile dysfunction treatment.
Two studies at Hospital for Special Surgery found that cartilage restoration procedures relieve pain and improve function in patients with articular cartilage damage. The procedures using different types of cartilage plugs showed a high degree of satisfaction among patients.
A new pain management technique, called an adductor canal block, provides effective pain relief while preserving muscle strength in ACL knee surgery patients. The study found a significant reduction in muscle weakness and falls compared to the current standard method.
A University of Alberta study found PRP injections to be effective in improving tissue healing, reducing pain, and increasing mobility in patients with chronically sore shoulders. The treatment involves injecting platelet-rich plasma into the affected area to augment the body's natural healing response.
A new study published by Hospital for Special Surgery recommends patients wait at least three months after a steroid injection to avoid an increased infection risk before undergoing hip replacement surgery. Researchers found that the immune system is weakened by corticosteroids, contributing to a higher risk of surgical site infections.
Takotsubo syndrome, also known as broken heart syndrome, can be triggered by both sad and happy emotional events. Researchers found that 20 patients developed the condition after a happy event, while 465 had occurred after sad and stressful events.
Patients aged under 45 and 75 years and older report greater pain and lower activity levels following TKR surgery. Despite comparable range of motion improvements across all age groups, these patients experience more challenges with daily activities.
A study from the University of Eastern Finland found that balloon angioplasty can successfully treat acute mesenteric ischemia (AMI), a condition often misdiagnosed in older patients. The procedure led to a significant improvement in mortality rates compared to earlier treatments.
Research reveals a direct link between economic insecurity and physical pain, with feelings of lack of control exacerbating the issue. The study found that individuals who experience financial stress report more physical pain and have reduced pain tolerance.
New evidence suggests that people feel less responsible for their actions when coerced into doing something. The study found that coercion leads to a small but significant increase in the perceived time interval between action and outcome.
Using human ligament samples and polarized-light-based imaging, the Penn team has identified microscopic features that prefigure where failure occurs. This insight could lead to new diagnostic techniques or therapies for sub-failure injuries.
A retrospective study found that freezing nerves before knee replacement surgery significantly improves patient outcomes, with shorter hospital stays and reduced opioid use. The treatment group had fewer knee symptoms and better local pain control, allowing patients to walk and function well enough to go home sooner.
Researchers found a significant increase in blood vessel and pain receptor growth among patients with calcific tendinitis, leading to chronic inflammation and severe pain. The study suggests new ways to manage the associated pain and may provide insights into other tendon disorders and diseases.
Cognitive developmental influences on preschool-age children's pain self-reporting are limited by factors such as memory, knowledge of magnitude, and language ability. Modifications for simplifying pain assessments, including using tools with few response options and considering past pain experiences, can improve accuracy.
Studies using advanced imaging techniques reveal changes in brain and spinal cord structure and function associated with diabetic peripheral neuropathy. Researchers believe that CNS factors contribute to the development of painful symptoms, providing new insights into the nature of DPN.
Researchers found that patients with two copies of a different allele showed more pain variability and more pain at the end of the day after physical activity. This study suggests tailored behavioral programs could be used sensitive to a person's genotype to increase physical activity and manage arthritis.
Researchers from KU Leuven identified histamine as a cause of abdominal pain in IBS patients, discovering that it makes the pain receptor TRPV1 hypersensitive. A pilot clinical study found that ebastine, an existing hay fever medicine, significantly reduced abdominal pain in IBS patients.
A study found that nations with higher prevalence of the A allele in the fatty acid amide hydrolase (FAAH) gene variant are also reported as happier. This allele helps prevent pain and enhances sensory pleasure. Climate, economics, and politics did not significantly influence happiness levels.
A study published in JAMA Surgery found that nearly one-third of patients who underwent Roux-en-Y gastric bypass surgery experienced hospitalization due to symptoms such as abdominal pain and fatigue. The risk of symptoms was higher among women, younger patients, smokers, unemployed individuals, and those with surgical symptoms before ...
A 33-year-old professional goalkeeper suffered an extremely rare complete rupture of his teres major muscle while playing a football match. He recovered after conservative treatment and physiotherapy, eventually returning to competition level without pain or limitation.
A 17-year-old woman contracted rat-bite fever from her pet rodents, a rare condition that can be treated. The case highlights the risk of infection from pet animals and the importance of proper hygiene.
Researchers at the University of Zurich found that a handful of positive experiences with strangers can increase empathy by triggering a learning effect in the brain. This leads to stronger empathic brain responses towards out-group members, driving more compassionate behavior.
A new study published in JAMA Internal Medicine found that while specialty prescribers concentrated opioid prescriptions, general practitioners wrote the most total prescriptions among Medicare prescribers. The authors analyzed 2013 Medicare data and focused on opioid prescriptions containing over 20 different opioids.
Researchers found that hip x-rays are unreliable for diagnosing hip osteoarthritis in most cases, potentially delaying treatment and missing affected individuals. The study suggests that patients with suspected hip OA should be treated regardless of x-ray confirmation.
A new study found that periarticular injections reduced postoperative hospital stay and number of inpatient physical therapy sessions after total knee replacement surgery. Patients who received these injections recovered quicker due to maintaining control over the quadriceps muscles, allowing for faster walking independently.
A new review of 45 years of medical literature found relatively few cases of meperidine-associated seizures, with coexisting conditions often contributing to the increased risk. The study concludes that meperidine's role as an effective anti-shivering agent should continue to be explored.
Researchers have investigated high-frequency repetitive sensory stimulation as a therapeutic approach for Complex Regional Pain Syndrome (CRPS) patients. The study showed significant improvement in tactile performance after stimulation, with individual patients reporting substantial pain relief.
A blood test can predict how quickly patients recover from surgery by identifying their unique immune state before the procedure, according to a new study. This simple test may help personalize recovery approaches and have a significant impact on perioperative medicine.
A nationwide study found that minorities are less likely to receive analgesic medications for abdominal pain at US emergency departments. Black and Hispanic patients experience prolonged ED lengths of stay and were less likely to be hospitalized for their ailments.
Researchers at WashU Medicine have created flexible, implantable devices that can activate and potentially block pain signals in the body before they reach the brain. The devices contain microLED lights that can stimulate specific nerve cells to alleviate pain.
Research from Hospital for Special Surgery found that community poverty significantly increases risk of pain and poor function following knee replacement surgery. Black patients with lower education levels are disproportionately affected, highlighting the need to address socioeconomic disparities in post-surgical outcomes.
A low-impact exercise program at senior centers in New York City's Chinatown and Flushing, Queens communities has helped decrease participants' pain and improve mobility. The program, led by bilingual instructors, reduced musculoskeletal pain by 32% and improved function in activities such as climbing stairs and lifting groceries.
A study of over 2,200 obese patients found that bariatric surgery leads to significant improvements in bodily pain, physical function, and walking speed. However, patient age, income level, depressive symptoms, and pre-existing medical conditions can affect the likelihood of improvement.
Researchers at Toyohashi University of Technology found that humans can empathize with humanoid robots in perceived pain. However, the beginning of the top-down process of empathy is weaker for robots than for humans. This study contributes to the development of human-friendly robots whom we feel sympathy for and comfortable with.
Researchers found that acupuncture and Alexander Technique lessons significantly reduced chronic neck pain by 32% and 31%, respectively, at 12 months. These interventions provided clinically relevant reductions in pain levels without medication use, offering new hope for patients with chronic neck pain.
A randomized, controlled trial found both acupuncture and the Alexander Technique led to significant long-term reductions in neck pain and associated disability compared with usual care. The interventions also showed high acceptability rates and greater adherence, leading to improved self-efficacy and outcomes.
A recent study found that stopping breastfeeding due to pain or physical difficulties increases the risk of postnatal depression. The study suggests investing in support systems to enable women to breastfeed successfully.
A pooled analysis of available evidence suggests that high levels of total cholesterol are associated with an increased risk of tendon abnormalities and pain. Chronic low-level inflammation, prompted by cholesterol build-up in immune cells, may be a key factor contributing to this link.
An expert argues that home is not always the best or preferred place to die, and that hospitals should be given more attention and resources for providing excellent end-of-life care. Dr. Kristian Pollock highlights the need for improved pain control and support services in both home and hospital settings.
Research reveals women with knee osteoarthritis have greater sensitivity to pain stimuli, such as heat and cold, and widespread pain. This study's findings may inform treatment strategies for both men and women.
Researchers at Temple University School of Medicine are testing the effectiveness of mirror therapy in reducing pain and improving mobility in combat veterans with complex orthopedic injuries or nerve damage. The study aims to assess whether this technique can help alleviate symptoms and improve quality of life for these individuals.
Researchers found that manipulating self-experienced pain affects empathy for pain in others through the endogenous opioid system. The study suggests empathy relies on simulation and is grounded in our own experiences, which may explain why feelings of others can affect us so immediately.
Researchers at Sahlgrenska Academy found that the Fugl-Meyer assessment scale can predict stroke patients who will develop upper limb spasticity within one year. This allows for early treatment to minimize pain, impaired function, and other repercussions of spasticity.
Newborns in clinical trials are often denied analgesia for minor painful procedures, despite international guidelines. A recent review found that up to 70% of control group babies received no pain treatment.
A randomized trial found that yoga improved physical health, pain, energy, mood, and daily activities in people with arthritis. The study also showed long-term improvements in physical function and walking speed.
A study published in JAMA Pediatrics found racial disparities in pain management among children with appendicitis in emergency departments, with black children receiving less pain medication and opioids. The study analyzed data from 2003 to 2010 and suggested that more research is needed to understand why such disparities exist.
A retrospective case series found specific epidural steroid injections to be effective in treating short-term pain from lumbar spinal stenosis. The study contradicts a previous NEJM study and suggests future trials using interlaminar injection with long-acting steroids.
A study published in Annals of Emergency Medicine found that children with broken bones or joint dislocations in northern Israel received equal pain relief, regardless of their ethnicity. The study, which lasted four years, including an 11-week period of armed conflict, showed that opioid therapy was administered to nearly all children...
A recent study found that depression is strongly associated with the frequency of chest pain in adults with and without underlying coronary artery disease. Patients with depression were three times more likely to experience more frequent chest pain than those without depression.
A new protein (C5orf30) has been identified as a genetic marker that can help regulate the severity of tissue damage caused by rheumatoid arthritis. This discovery enables early identification of patients at risk of severe joint damage, allowing for fast-tracked treatment with more aggressive therapies.
A new algorithm using a highly sensitive troponin I assay can reduce mortality and cut triage times to one hour for patients with suspected acute myocardial infarction. The algorithm allows for safe discharge or rapid treatment initiation, enabling better resource utilization.