A study by researchers at UCSF Medical Center found that the electrocardiogram is highly inaccurate for patients with left bundle-branch block (LBBB), leading to under-treatment. This affects approximately 100,000 Americans with LBBB who experience myocardial infarction every year.
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A new study found that clot-busting drugs can save legs as effectively as invasive surgery, reducing the need for open surgical procedures by over 30%. The experimental drug, recombinant urokinase, showed no significant difference in death or amputation rates between surgical and non-surgical patients.
Researchers at Johns Hopkins Medicine have identified a unique molecular defect responsible for polycythemia vera, a blood disorder that can be difficult to diagnose. The finding may lead to the development of a definitive test for the condition, which could potentially increase patient lifespan.
Researchers found that a vitamin supplement with folic acid, B-6, and B-12 reduced homocysteine levels and improved biochemical markers in the blood of 27 patients who had suffered a stroke. The study suggests that lowering homocysteine may have multiple biological effects on endothelial cells.
Researchers found that low-frequency ultrasound enhances the effectiveness of thrombolytic drugs in dissolving blood clots deep within the brain. This combination therapy may reduce the duration and doses of medication needed, minimizing risks of bleeding and other complications associated with stroke treatment.
A new ultrasound contrast agent, Levovist, has been used to treat an ischemic stroke in a German patient. The agent revealed the blocked artery and allowed doctors to dissolve the clot with thrombolytic rTPA, restoring blood flow to the brain within 40 minutes of admission.
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Researchers developed CLOTSIM, a computer model simulating blood clot dissolution, to provide critical information on thrombolytic agents. The program helps predict clinical outcomes and tailor therapies to reduce patient risks.