Articles tagged with Drug Costs
Patients treated first with metformin were less likely to require treatment intensification compared to those who started with sulfonylureas, thiazolidinediones, or DPP-4 inhibitors. Metformin also reduced the need for added insulin and was not associated with increased rates of hypoglycemia or cardiovascular events.
Researchers found that generic aromatase inhibitors increased treatment adherence by 50% compared to brand-name counterparts, while also decreasing co-payment costs. The study highlights the critical need to address medication non-adherence, particularly in the context of costly oral cancer therapies.
Researchers found that treating inmates with sofosbuvir is cost-effective compared to other treatments approved by the FDA. The study suggests that the treatment can add up to 2.1 quality-adjusted life years and save healthcare programs from paying out more in the future.
A cost-value review of specialty versus traditional drugs found that specialty drugs offered greater gains for patients despite higher costs. Specialty drug coupons helped reduce patient out-of-pocket costs but may decrease insurers' ability to manage drugs.
The study will evaluate the benefits of genetic testing to guide medication decisions for patients with depression or schizophrenia, including clinical outcomes and cost benefits. The research aims to provide personalized treatment recommendations tailored to individual patient genetics.
The number of antibiotics available for clinical use has declined to 96 from a peak of 113 in 2000, with the rate of withdrawals being double the rate of new introductions. Pharmaceutical companies are leaving the antibiotic space due to financial constraints and patent law, forcing research universities to step in.
A study published in Journal of Clinical Oncology found that the 2005 Medicare law had no significant impact on reducing chemotherapy drug costs, contradicting economists' expectations. Instead, cancer care costs skyrocketed during the decade after the law passed.
The use of generic discount drug programs (GDDPs) has grown significantly since their introduction in 2006, with a notable increase in racial/ethnic minorities. GDDPs can help reduce medication costs and improve access to drug therapy for vulnerable populations.
The American College of Physicians recommends Kegel exercises, bladder training, and weight loss as effective treatments for stress and urgency urinary incontinence. Non-surgical treatment options are recommended over medication to minimize side effects and costs.
The American College of Physicians (ACP) recommends Kegel exercises, bladder training, and weight loss as effective nonsurgical treatment options for women with urinary incontinence. Generic statins are also shown to improve adherence to medication and clinical outcomes compared to brand-name drugs. Chiropractic care coupled with exerc...
Researchers found that patients taking generic statins were more likely to adhere to their medication and had a significantly lower rate of cardiovascular events and death. Generic statins were also associated with improved clinical outcomes due to lower out-of-pocket costs.
A recent study suggests that treating mildly elevated blood pressure in low-risk individuals may not be effective in reducing cardiovascular disease or death. Experts urge clinicians to re-examine the threshold for treatment and promote lifestyle changes, such as weight loss and increased exercise, instead of relying on medication.
A collaborative study estimated long-term costs and health outcomes of depression-related absence compared to working employees with depression. Researchers found that continuing to work while experiencing a depressive illness may offer certain health benefits.
A Penn researcher and CVS Health physician suggest an alternative payment model for gene therapy, which would replace single large payments with annuity payments over a defined period. This approach could help ensure sufficient investments in expensive gene therapies by spreading out payments and linking them to evidence of continued e...
A three-year study led by the University of Liverpool will investigate the effectiveness of two Behçet's syndrome treatments, potentially saving the NHS £500k. The research aims to identify factors that make medicine work for some patients but not others, allowing doctors to prescribe evidence-based treatment.
A commentary calls for physicians to carefully review older patients' medication lists and consider their anticipated life expectancy, goals of care, and treatment targets. This approach can help reduce the number of unnecessary prescriptions and minimize harm from medications in older adults.
A recent study published in JAMA Internal Medicine found that patients with advanced dementia are still being prescribed medications with little to no proven benefit. The study analyzed data from over 5,400 nursing home residents and found that nearly 54% received at least one questionable medication.
The FOCUS Study found that patients taking a polypill had higher adherence rates compared to those receiving individual medications. The study identified factors contributing to non-adherence, including age, depression, and complexity of treatment.
A new study found that 27% of rheumatoid arthritis patients in the UK failed to take their expensive anti-TNF therapy as prescribed. Non-adherence to medication reduced its effectiveness and worsened disease outcomes, highlighting a significant concern for healthcare resources.
Women seek anti-aging clinicians to treat menopausal symptoms, valuing personalized attention and perceived safety of bioidentical hormones. The study found that these women prioritize relieving symptoms, feeling energized, and avoiding chronic illnesses associated with aging.
The 340B program is facing critical issues such as eligibility definition, compliance, and transparency. RAND researchers estimate that the program accounts for $6 billion in outpatient drug spending and provides savings of $1.6 billion for eligible safety net providers.
A study led by the University of Pittsburgh School of Pharmacy found that community pharmacist interventions can significantly boost drug adherence rates. The project showed a 3-4% increase in medication adherence across five common medication classes, resulting in substantial cost savings for healthcare systems. By leveraging pharmaci...
A combination pill taking key medications for heart disease prevention may reduce costs and improve adherence to medication recommendations. The polypill has been proposed as a low-cost strategy to improve secondary prevention in nations with limited resources.
Researchers will use radioactive labelling to track where key materials used in nanomedicines accumulate in the body. This study aims to inform regulation and development of safer nanomedicine options for chronic conditions.
A medication called ferric citrate may reduce the need for dialysis patients to take multiple drugs that treat complications related to kidney disease. Ferric citrate binds phosphorus, increases iron stores, and decreases the need for iron and anemia medications, leading to fewer hospitalizations.
A new assay developed by Oregon State University can detect counterfeit malaria drugs at a cost of a few cents, saving thousands of lives annually. The technology uses paper-based microfluidics to verify the presence and level of artesunate, a crucial drug for treating serious malaria cases.
Using an expensive agent to prevent blood clots in kidney failure patients' dialysis catheters may reduce overall medical complications and lower healthcare costs. A recent clinical trial found that the increased cost of this medication was partially offset by lower costs for managing complications.
A new methodology tracks wholesale powdered cocaine prices in 112 cities to identify city-to-city links for the transit of the drug. Cities in the southern U.S. and along the west coast are source cities, while those in the north and northeast are destination cities.
Researchers found that if all eye doctors prescribed the less expensive bevacizumab instead of ranibizumab for treating common eye diseases, Medicare could save $18 billion over a decade. This would also result in patients saving $4.6 billion in co-pays and the private healthcare system saving an additional $29 billion.
Researchers propose reassigning low-income Medicare beneficiaries to their most affordable medication plans. The change could result in $5 billion in savings and fewer prescription restrictions for eligible individuals.
A recent study published in the Journal of Clinical Psychiatry found that letting patients choose their PTSD treatment can lead to significant cost savings and a higher quality of life. The study showed that patients who were allowed to select their own treatment spent an average of $1,622 less per year compared to those who were assig...
Two studies in JAMA Ophthalmology investigated glaucoma medication adherence, finding that a sizable number of patients struggle to use prescribed eye drops. Electronic monitoring revealed that 82.8% of patients took their medication correctly on at least 75% of days, highlighting the need for risk calculators to identify nonadherent p...
University of Houston pharmacy students earned statewide awards for excellence in leadership, professional service and clinical skills. Two teams won the second- and fourth-year Pharmacy Doctorate student divisions in the clinical skills competition.
Researchers found extended-release Naltrexone to be more effective than other medications in reducing substance abuse and hospital admissions. The medication offers significant savings due to lower healthcare utilization costs.
The NHS prescription charge is outdated and unfair, say the Drug and Therapeutics Bulletin. Many exemptions are illogical and adding to the tax on medicines, it argues. Several alternative arrangements have been suggested, including a dispensing fee for patients.
A comprehensive analysis of over 120 studies reveals that medications like acamprosate and oral naltrexone show promise in decreasing alcohol consumption, with an average number needed to treat (NNT) of 12 for both. These findings highlight the potential benefits of medication-assisted treatment for adults with alcohol use disorders.
Two medications, acamprosate and oral naltrexone, have shown promise in reducing return to drinking and improving other drinking outcomes. The study provides additional options for clinicians to address alcohol use disorders, a global concern associated with many health problems.
A recent review warns of the dangers of smart drugs on young people's developing brains, highlighting the potential for long-term impairments and decreased brain plasticity. Methylphenidate and modafinil, two popular smart drugs, have been found to cause these effects in young brains.
A new study found that Orlistat patients attribute weight loss failure to side effects or ineffective medication. Patients described barriers such as psychological and physical health issues, relationships, and alternative methods of weight loss, emphasizing the need for better patient support and dietary education.
Research finds that lowering copayments for cardiovascular medications following a heart attack significantly improves adherence and reduces adverse events among nonwhite patients. Providing full drug coverage increased medication adherence and reduced major vascular events by 35% and healthcare spending by 70%.
Researchers at the Lunenfeld-Tanenbaum Research Institute used baker's yeast to study drug interactions, finding that one-fifth of combinations suppress each other's effectiveness and increasing the risk of adverse reactions. The study's findings have implications for personalized medicine and optimization of combination therapies.
The report highlights the importance of sharing prescription monitoring data with third-party payers to detect inappropriate prescribing and dispensing, ultimately reducing opioid abuse and deaths. The recommendations aim to enhance insurer capabilities in monitoring prescribing patterns and improving patient safety.
A study found that free medication samples in dermatology offices change prescribing practices for acne and rosacea. Branded drugs accounted for 79% of prescriptions, while generic alternatives were less common. This may lead to higher prescription costs.
A study by Stanford researchers found that dermatologists with access to free drug samples prescribe more expensive brand-name drugs, despite some benefits of the samples in helping uninsured patients. The study suggests that physicians may not be aware of cost differences between brand-name and generic drugs.
A study led by Purdue University found that medication therapy management by phone reduced hospitalizations by 86% in low-risk Medicare patients, who were three times less likely to be hospitalized. However, the intervention had no significant impact on higher-risk patients, highlighting the need for tailored strategies.
Researchers from Universidad Carlos III de Madrid find that price controls can increase efficiency and lower prices for generic medicines. The study suggests alternative instruments to direct regulation, promoting competition and transparency.
A new device simulates the human gut and its pH gradients to test drug absorption, reducing clinical trial costs. This breakthrough could lead to more affordable medicines with reduced development costs passed on to customers.
A new study reveals that one in seven critically ill patients who received mechanical ventilation experience anxiety, depression, and insomnia. The research highlights the need for improved prevention and treatment of psychological problems in these patients.
A new method for purifying peptide-based drugs has been developed by a chemist at Michigan Technological University, separating perfect peptides from those that don't make the grade in just two hours. The process reduces waste and is cheaper than existing methods, offering a promising alternative for treating diseases like cancer and HIV.
A new MIT robot developed by Hermano Igo Krebs can help pharmaceutical companies speed up drug development for stroke medications. By using the robot's measurements, companies may only need to test 240 patients to determine whether a drug works, reducing time and cost by 70%.
A study of 230 bipolar I disorder patients found that nearly a third were taking four or more psychiatric medications, with an average of six different drugs. Women were significantly more likely to experience complex polypharmacy, taking 68% of these high medication burden cases.
A new study finds that heart attack survivors, particularly black and Hispanic women, are less likely to adhere to prescribed medications. The researchers highlight the need for targeted interventions to improve long-term adherence and optimal outcomes.
Research at the University of North Carolina found that patients with higher co-payments were 70% more likely to stop taking their cancer treatment and 42% more likely to skip doses. The cost of many new pharmaceuticals can exceed $100,000 per year.
The DTB suggests that England should reject new drugs if pharmaceutical companies fail to provide supporting evidence, reducing duplication of effort and postcode availability. This follows the example of Scotland and Wales, where such decisions are made by a single UK appraisal service.
Couples undergoing fertility treatment face significant out-of-pocket expenses, with IVF cycles costing up to $19,234, while medication-only treatments cost around $912. The study's findings aim to inform couples and physicians about the true costs of infertility care.
A new study shows that telemedicine consultations can effectively manage Parkinson's symptoms and improve quality of life. Virtual house calls enable individuals with the condition to live independently while receiving specialized care.
A study found that medication and individual psychotherapy are effective treatments for alcohol dependence, particularly when patients commit to the treatment. The stepped-care approach, which escalates services as needed, also showed promise in reducing heavy drinking and relapse rates.
Scientists have made a breakthrough in understanding the regulation of PDE3A enzymes, which regulate cardiac contractility. The discovery of individual isoforms and their interactions with different proteins suggests that developing targeted drugs could reduce sudden cardiac death risk.
A study found that patients who received personalized attention from a pharmacist improved their medication adherence rates, with 89.3% adherent in the intervention group compared to 73.9% in usual care. However, there was no significant difference in achieving blood pressure and low-density lipoprotein cholesterol level targets.
The 'Path to 2025' Alzheimer's Disease Summit highlights the need for streamlined drug development to tackle the disease. The report estimates that current total cost of bringing an effective Alzheimer's treatment to market approaches $6 billion, nearly three times the industry average.